| Debus, Jürgen |
CyberChallenge, NCT05378633: The Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases? |
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| Recruiting | 2 | 190 | Europe | SRS, Whole Brain Radiotherapy | University Hospital Heidelberg | Brain Metastases, Nsclc | 02/25 | 02/26 | | |
| Active, not recruiting | 2 | 180 | Europe | Chemotherapy, all brands of 5-fluorouracil (5-FU) are allowed, all brands of Mitomycin C (MMC) are allowed, Radiation, Durvalumab, PD-L1 inhibitor | Goethe University, German Cancer Aid, AstraZeneca | Anal Cancer, Anal Carcinoma, Anal Cancer Stage III, Anal Cancer Stage II | 12/26 | 03/27 | | |
PRESTO, NCT05713838: Organ Preservation With Durvalumab-based Immunotherapy in Combination With Chemoradiation as Definitive Therapy for Early Stage Esophageal Adenocarcinoma With Indication for Radical Surgery |
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| Recruiting | 2 | 32 | Europe | Durvalumab, IMFINZI, FLOT, mFOLFOX-6, Radiotherapy | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | Esophagus Adenocarcinoma | 12/25 | 12/28 | | |
| Not yet recruiting | 2 | 276 | Europe | dose-escalated radiochemotherapy, dose-escalated radiochemotherapy with carbon ion boost, standard radiochemotherapy | Technische Universität Dresden | Head and Neck Squamous Cell Carcinoma | 09/25 | 09/27 | | |
Radcav, NCT05871307: Neoadjuvant vs. Intraoperative vs. Adjuvant Resection Cavity Radiotherapy of Brain Metastases |
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| Recruiting | 2 | 90 | Europe | Preoperative Radiotherapy, Intraoperative Radiation, Postoperative Radiotherapy | University Hospital Heidelberg | Brain Metastases, Radiotherapy | 05/26 | 05/28 | | |
MAGELLAN, NCT04925583: Magnetic Resonance Guided Adaptive Stereotactic Body Radiotherapy for Lung Tumors in Ultracentral Location |
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| Recruiting | 1 | 38 | Europe | Stereotactic body radiotherapy (SBRT) | University Hospital Heidelberg | Lung Cancer | 11/25 | 11/26 | | |
| Recruiting | N/A | 202 | Europe | intraoperative radiotherapy, IORT, whole breast irradiation, WBI | University Hospital Heidelberg | Breast Cancer | 09/24 | 05/30 | | |
NCT04437030: Multiparametric Photoacoustic Imaging in the Course of Radiation Therapy of Malignant Head and Neck Tumors |
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| Completed | N/A | 30 | Europe | MSOT Acuity Echo device | University Hospital Heidelberg | Head and Neck Cancer | 01/22 | 07/23 | | |
DILANA, NCT04094454: Intrafractional Vaginal Dilation in Anal Cancer Patients Undergoing Pelvic Radiotherapy |
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| Recruiting | N/A | 60 | Europe | special tampon with a diameter of 28mm, standard tampon with a diameter of 12-13mm | Juergen Debus | Anal Cancer | 10/24 | 10/25 | | |
CARE, NCT04185974: Carbon Ion Re-Radiotherapy in Patients With Recurrent or Progressive Locally Advanced Head-and-Neck Cancer |
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| Recruiting | N/A | 72 | Europe | C12 re-irradiation, Photon re-irradiation | University Hospital Heidelberg | Locally Advanced Head-and-Neck Cancer | 11/24 | 11/24 | | |
DELPHI, NCT03396718: De-escalation of Adjuvant Radio (chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas |
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| Recruiting | N/A | 304 | Europe | De-escalation radio(chemo)therapy - Level 1, De-escalation radio(chemo)therapy - Level 2, Standard radio(chemotherapy) | Technische Universität Dresden, German Cancer Research Center, National Center for Tumor Diseases (NCT) Dresden, National Center for Tumor Diseases, Heidelberg, Radiation Oncology Working Group of the German Cancer Society | Head-and-neck Squamous Cell Carcinoma | 11/29 | 11/32 | | |
