Lucile Packard Children's Hospital
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 33 Trials 
75 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Hammer, Gregory
ANA01, NCT03427736: Anesthetics and Analgesics in Children

Recruiting
N/A
460
Canada, US
Ketorolac Tromethamine, Toradol, Hydromorphone, Hydromorphone hydrochloride, Dilaudid, Ketamine, Ketamine Hydrochloride, Oxycodone, Oxycodone Hydrochloride, Morphine, Morphine Sulfate
Kanecia Obie Zimmerman, The Emmes Company, LLC
Anesthesia, Pain
06/25
06/25
Lee, Christine H
DPPOS, NCT00038727: Diabetes Prevention Program Outcomes Study

Active, not recruiting
3
2779
US
DPPOS Group Lifestyle, Metformin, Glucophage, DPPOS Boost Lifestyle, Intensive Lifestyle Group Session, Intensive lifestyle session (ILS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Aging (NIA), National Institute on Minority Health and Health Disparities (NIMHD), National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI), National Eye Institute (NEI), National Center for Research Resources (NCRR), Office of Research on Women's Health (ORWH), Centers for Disease Control and Prevention, American Diabetes Association, Indian Health Service, General Clinical Research Program, US Department of Veterans Affairs
Diabetes Mellitus, Cancer, CVD
10/24
01/25
ENGOT-EN20, NCT05611931 / 2022-002540-42: Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

Jul 2024 - Dec 2024: Top-line data from XPORT-EC trial in participants with TP53 wild type endometrial cancer
Recruiting
3
220
Europe, Canada, US, RoW
Selinexor, KPT-330, Matching Placebo for selinexor
Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group
Endometrial Cancer
01/25
01/28
RAMP 301, NCT06072781: A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Recruiting
3
270
Europe, Canada, US, RoW
avutometinib, avutometinib (VS-6766), Defactinib, defactinib (VS-6063), Pegylated liposomal doxorubicin, Caelyx, Doxil, Lipodox, Paclitaxel, Nov-Onxol, Onxol, Navaplus, Taxol, Letrozole, Femara, Anastrozole, Arimidex
Verastem, Inc., GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Australia New Zealand Gynaecological Oncology Group, Korean Gynecologic Oncology Group
Low Grade Serous Ovarian Cancer
10/28
02/31
REFRaME-O1, NCT05870748: A Study to Investigate the Efficacy and Safety of Luveltamab Tazevibulin Versus Investigator's Choice (IC) Chemotherapy in Women With Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing FOLR1

Recruiting
2/3
600
Canada, US, RoW
Luveltamab tazevibulin, STRO-002, Luvelta, Pegfilgrastim, Neulasta, Gemcitabine, Paclitaxel, Pegylated liposomal doxorubicin, Topotecan
Sutro Biopharma, Inc., GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Asia-Pacific Gynecologic Oncology Trials Group (APGOT)
Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, Platinum-resistant Ovarian Cancer
08/27
02/28
TETON, NCT04814108: A Study of ZN-c3 in Women With Recurrent or Persistent Uterine Serous Carcinoma

Recruiting
2
76
Canada, US, RoW
ZN-c3, azenosertib, KP-2638
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Uterine Serous Carcinoma
11/24
05/25
PROFECTA-II, NCT04374630: Study with Afuresertib and Paclitaxel in Platinum Resistant Ovarian

Completed
2
150
US, RoW
Paclitaxel, Afuresertib, LAE002
Laekna Limited
Platinum-resistant Ovarian Cancer
07/23
06/24
PICCOLO, NCT05041257: Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers

Hourglass Oct 2024 - Dec 2024 : Approval for 2L+ FRα +ve PROC
Hourglass Jan 2024 - Jun 2024 : FDA action date for approval for ovarian cancer with high FRAC
Hourglass Jan 2024 - Jun 2024 : sBLA approval for ovarian cancer
Hourglass Jan 2023 - Dec 2023 : ORR data from PICCOLO trial for platinum sensitive ovarian cancer
Completed
2
79
Europe, Canada, US, RoW
Mirvetuximab soravtansine, MIRV, IMGN853
AbbVie
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
01/24
12/24
ENGOT-ov60, NCT04625270 / 2020-004264-26: A Study of Avutometinib (VS-6766) V. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer with and Without a KRAS Mutation

Active, not recruiting
2
225
Europe, Canada, US
avutometinib (VS-6766), avutometinib (VS-6766) and defactinib, avutometinib (VS-6766) and VS-6063
Verastem, Inc., European Network of Gynaecological Oncological Trial Groups (ENGOT), GOG Foundation
Low Grade Ovarian Serous Adenocarcinoma, Ovarian Cancer
11/24
12/26
NCT04202211: FMT for Remission of Active Ulcerative Colitis in Adults

Withdrawn
2
145
Canada
FMT oral, FMT enema, Placebo oral, Placebo enema
University of British Columbia, Crohn's and Colitis Canada
Ulcerative Colitis, Inflammatory Bowel Diseases
12/24
12/28
PRESERVE-004, NCT05446298: ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer

Active, not recruiting
2
58
US
ONC-392, A humanized anti-CTLA4 IgG1 monoclonal antibody made by OncoC4, Inc., Pembrolizumab, MK3475, Keytruda
OncoC4, Inc., Merck Sharp & Dohme LLC, GOG Foundation
Ovarian Cancer, High Grade Serous Adenocarcinoma of Ovary, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
06/25
06/26
UTMOST2, NCT06999798: An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The Trial

Not yet recruiting
2
20
US
Diagnostic Mammography, diagnostic mammogram, Resection, Surgical Resection, Ultrasound Imaging, 2-Dimensional Grayscale Ultrasound Imaging, 2-Dimensional Ultrasound Imaging, 2D-US, Ultrasonography, Ultrasound, Ultrasound Test, Ultrasound, Medical, US, Twinkling Marker Placement, Twinkle Marker, Mayo Twinkle Marker, Biopsy Twinkle Marker, Biopsy Twinkling Marker, Mayo-designed Twinkling Marker
Mayo Clinic, National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Locally Advanced Breast Carcinoma
07/26
07/26
NCT03806803: Multicentre Blinded Comparison of Lyophilized Sterile Fecal Filtrate to Lyophilized Fecal Microbiota Transplant in Recurrent Clostridioides Difficile Infection

Completed
2
138
Canada
Lyophilized fecal microbiota transplant, Lyophilized sterile fecal filtrate
University of Alberta, University of British Columbia, University of Calgary, McGill University
Clostridia Difficile Colitis, Clostridium Difficile Diarrhea
03/24
03/24
CASTLE, NCT05613946: Contrast-Enhanced Ultrasound and Shear Wave Elastography for the Treatment of Lymphedema

Completed
1
26
US
Lumason, sulfur hexafluoride lipid-type A microspheres, Optison, perflutren protein-type A microspheres, Definity, perflutren lipid microsphere
Mayo Clinic
Lymphedema Arm
06/24
06/24
AMPS, NCT04213846: Alcohol & Mobile Phone Study to Reduce High-risk Alcohol Use and Consequences

Completed
N/A
408
US
Experimental: Mobile Alcohol Expectancy Intervention
University of Washington, National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol; Use, Problem
04/22
04/22
NCT06441188: Sonography of the Nipple Areolar Complex

Completed
N/A
20
US
Thin layer conventional ultrasound coupling gel, Thick layer of conventional ultrasound coupling gel, Thin conventional ultrasound coupling gel pad, Thick conventional ultrasound coupling gel pad
Mayo Clinic
Healthy
10/24
10/24
NCT05547347: Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients with Locally Advanced Breast Cancer

Enrolling by invitation
N/A
15
US
Magnetic Resonance Imaging, Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, Mammogram, Ultrasound, Ultrasound-Guided Biopsy, Ultrasound Guided Biopsy, Twinkle marker
Mayo Clinic, National Cancer Institute (NCI)
Anatomic Stage III Breast Cancer AJCC V8, Locally Advanced Breast Carcinoma, Resectable Breast Carcinoma
12/25
12/25
NCT04692818: 3D Ultrasound Breast Imaging

Recruiting
N/A
125
US
GE Logiq E10 clinical ultrasound scanner, Verasonics research scanner
Mayo Clinic, United States Department of Defense
Breast Tumor
12/25
12/26
NCT06873802: ZTE MRI Pulse Sequence Use for Visualization of Bone Cement, Breast Biopsy Markers

Recruiting
N/A
20
US
Non-Interventional Study
Mayo Clinic, National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Breast Carcinoma
12/25
12/25
FETO, NCT05461222: Fetal Endoscopic Tracheal Occlusion () for Severe Congenital Diaphragmatic Hernia

Recruiting
N/A
15
US
Balt "Goldballoon"
Yair Blumenfeld
Congenital Diaphragmatic Hernia
08/25
08/27
NCT07011615: Feasibility/Acceptability of a Brief Motivational Intervention for Frequent/High-Intensity Cannabis Use

Not yet recruiting
N/A
120
NA
Brief Motivational Mobile Health (mHealth) Intervention, Psychoeducational Attention Control (AC)
University of Washington, National Institute on Drug Abuse (NIDA)
Cannabis Use
09/26
09/26
ROCC, NCT04831580: A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

Recruiting
N/A
840
Canada, US
da Vinci, open surgery
GOG Foundation, Intuitive Foundation
Cervical Cancer
08/28
08/29
Shew, Stephen B
NCT03730454: Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair

Active, not recruiting
N/A
142
US
Transanastomotic Tube (5FR), No Transanastomotic Tube
Phoenix Children's Hospital
Esophageal Atresia, Tracheoesophageal Fistula
02/25
02/26
Newton, Peter
NCT04058561: Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals

Active, not recruiting
N/A
210
Europe, Canada, US, RoW
MAGEC® Spinal Bracing And Distraction System
Pediatric Spine Foundation, Columbia University
Early-Onset Scoliosis Deformity of Spine
12/27
12/27
NCT01661959: Adolescent Idiopathic Scoliosis Outcomes Database Registry

Enrolling by invitation
N/A
10000
Canada, US
Setting Scoliosis Straight Foundation, DePuy Spine, NuVasive
Adolescent Idiopathic Scoliosis
12/25
12/25
PCPS, NCT00680264: Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy

Recruiting
N/A
402
Canada, US
Setting Scoliosis Straight Foundation, K2M, Inc.
Cerebral Palsy, Scoliosis
12/25
12/25
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
NCT04505579: The Tether™ - Vertebral Body Tethering System Post Approval Study

Recruiting
N/A
200
US
Anterior Vertebral Body Tethering, AVBT
ZimVie, Setting Scoliosis Straight Foundation, Exponent, Inc.
Scoliosis Idiopathic
08/27
12/27
NCT02434003: Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis

Recruiting
N/A
1200
Europe, Canada, Japan, US, RoW
St. Justine's Hospital, Queen Mary Hospital, Hong Kong, The Meijo Hospital, Nagoya, Japan, National University of Singapore, Hopital Universitaire Robert-Debre, Alfred I. duPont Hospital for Children, Nicklaus Children's Hospital f/k/a Miami Children's Hospital, Rady Children's Hospital, San Diego
Scoliosis
12/27
12/27
Carvalho, Brendan
NCT05488457: Oxytocin Pharmacokinetics and Pharmacodynamics

Recruiting
2
100
US
deuterated oxytocin (d5OT), Deuterium-labeled oxytocin
University of Chicago, Stanford University
Post Partum Hemorrhage, Cesarean Section Complications, Blood Loss
09/25
12/25
NCT04749043: Virtual Reality Compared to Nitrous Oxide for Labor Analgesia

Completed
N/A
20
US
Oculus Quest 2 Virtual Reality Device, Nitrous oxide
Brendan Carvalho
Labor Pain
12/23
12/23
NCT03975660: Evaluation of Objective Pain Measurement Device

Completed
N/A
130
US
Pain Measurement Device
Stanford University
Pain, Analgesia, Labor Pain
10/23
10/23
NCT06030063: The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

Recruiting
N/A
5000
Canada, US
Yale University
Cesarean Delivery, General Anesthesia
09/28
09/29
Sultan, Pervez
NCT05065203: Evaluation of Inpatient Sleep and Activity Following Childbirth

Completed
N/A
78
US
planned or unplanned Cesarean, operative, or non operative delivery
Stanford University
Sleep
09/22
01/23
NCT04358757: Immune and Physical Recovery Following Cesarean Delivery

Completed
N/A
60
US
Elective cesarean delivery
Stanford University
Cesarean Delivery
09/23
12/23
Daldrup-Link, Heike
NCT02893293: Imaging of Osteonecrosis With Ferumoxytol-Enhanced MRI

Completed
4
14
US
Ferumoxytol-enhanced magnetic resonance imaging, Magentic Resonance Imaging, MRI
Stanford University
Osteonecrosis
10/23
10/23
NCT01336803: Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI

Completed
2
32
US
Feraheme, ferumoxytol, Magnetic Resonance Imaging (MRI) scan, Magnetic Resonance (MR) scan
Heike E Daldrup-Link
Bone Cancer, Chondrosarcoma, Ewing's Sarcoma, Osteosarcoma, Rhabdomyosarcoma, Bone Necrosis, Bone Sarcoma, Osteomyelitis
07/14
10/23
NCT01542879: Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer

Recruiting
1/2
75
US
WB-DW-MR scan, Whole Body Diffusion Weighted MR scan, 18-F-FDG PET scan, Fludeoxyglucose PET scan, Ferumoxytol, feraheme, 18-F-FDG PET/MR scan
Heike E Daldrup-Link
Cancer
10/25
12/26
NCT03458520: Pediatric PET/MR Image Registry

Recruiting
N/A
100
US
PET/MR imaging, positron emission tomography, MR imaging, magnetic resonance imaging, PET/CT imaging, computed tomography
Stanford University, National Cancer Institute (NCI)
Soft Tissue, Lymphoma, Osteosarcoma
09/25
09/25
Enns, Gregory M
NCT05099640 / 2021-000474-29: A Study of PTC923 in Participants With Phenylketonuria

Completed
3
157
Europe, Canada, US, RoW
PTC923, Placebo
PTC Therapeutics
Phenylketonuria
04/23
05/23
SYNPHENY-3, NCT05764239: Efficacy and Safety of SYNB1934 in Patients With PKU

Terminated
3
35
Canada, US, RoW
SYNB1934v1, Placebo
Synlogic
Phenylketonuria
03/24
03/24
NCT05166161 / 2021-000497-28: A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria

Recruiting
3
200
Europe, Canada, Japan, US, RoW
PTC923, Sepiapterin
PTC Therapeutics
Phenylketonuria
04/26
04/26
NCT01370447: EPI-743 for Mitochondrial Respiratory Chain Diseases

No Longer Available
2
94
US
EPI-743, Vincerinone, Vatiquinone
PTC Therapeutics
Mitochondrial Diseases
 
 
NCT00237315: Longitudinal Study of Urea Cycle Disorders

Recruiting
N/A
1500
Europe, Canada, US
Andrea Gropman, National Center for Research Resources (NCRR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Rare Diseases Clinical Research Network
Brain Diseases, Metabolic, Inborn, Amino Acid Metabolism, Inborn Errors, Urea Cycle Disorders
07/25
07/26
NAMDC, NCT01694940: North American Mitochondrial Disease Consortium Patient Registry and Biorepository

Recruiting
N/A
1000
Canada, US
Columbia University, National Institute of Neurological Disorders and Stroke (NINDS)
Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
12/25
12/25
NCT03115086: The REPLACE Registry for Cholbam® (Cholic Acid)

Active, not recruiting
N/A
55
US
Cholbam
Mirum Pharmaceuticals, Inc.
Bile Acid Synthesis Disorders
07/38
07/39
Naviaux, Robert
NAMDC, NCT01694940: North American Mitochondrial Disease Consortium Patient Registry and Biorepository

Recruiting
N/A
1000
Canada, US
Columbia University, National Institute of Neurological Disorders and Stroke (NINDS)
Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
12/25
12/25
Muehe, Anne
NCT01542879: Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer

Recruiting
1/2
75
US
WB-DW-MR scan, Whole Body Diffusion Weighted MR scan, 18-F-FDG PET scan, Fludeoxyglucose PET scan, Ferumoxytol, feraheme, 18-F-FDG PET/MR scan
Heike E Daldrup-Link
Cancer
10/25
12/26
NCT03458520: Pediatric PET/MR Image Registry

Recruiting
N/A
100
US
PET/MR imaging, positron emission tomography, MR imaging, magnetic resonance imaging, PET/CT imaging, computed tomography
Stanford University, National Cancer Institute (NCI)
Soft Tissue, Lymphoma, Osteosarcoma
09/25
09/25
Blumenfeld, Yair
RAFT, NCT03101891: Renal Anhydramnios Fetal Therapy

Active, not recruiting
1
70
US
Serial amnioinfusions with isotonic fluid, Renal Anhydramnios Fetal Therapy (RAFT), Spinal needle, Obstetrics and gynecology needle, Isotonic fluid, Normal saline, Lactated ringers solution
Johns Hopkins University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Anhydramnios, Potter Syndrome, Lung Hypoplasia, Multicystic Dysplastic Kidney, Multicystic Renal Dysplasia, Bilateral, Lower Urinary Tract Obstructive Syndrome, Fetal Renal Anomaly
03/25
02/30
FETO, NCT05461222: Fetal Endoscopic Tracheal Occlusion () for Severe Congenital Diaphragmatic Hernia

Recruiting
N/A
15
US
Balt "Goldballoon"
Yair Blumenfeld
Congenital Diaphragmatic Hernia
08/25
08/27
NCT02774746: Gastroschisis Outcomes of Delivery (GOOD) Study

Recruiting
N/A
800
US
35-week delivery, 38-week delivery
Medical College of Wisconsin
Gastroschisis
03/27
03/27
Chao, Stephanie D
REACT-AF, NCT05836987: The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Recruiting
3
5350
US
AFSW Guided DOAC, Apple Watch, Continuous DOAC therapy, Oral Anticoagulation therapy
Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI)
Atrial Fibrillation
07/29
07/29
NCT05608460: Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study

Recruiting
N/A
15700
US
University of Utah
Cervical Spine Fracture
08/25
08/25
Meyer, Marisa
ANA01, NCT03427736: Anesthetics and Analgesics in Children

Recruiting
N/A
460
Canada, US
Ketorolac Tromethamine, Toradol, Hydromorphone, Hydromorphone hydrochloride, Dilaudid, Ketamine, Ketamine Hydrochloride, Oxycodone, Oxycodone Hydrochloride, Morphine, Morphine Sulfate
Kanecia Obie Zimmerman, The Emmes Company, LLC
Anesthesia, Pain
06/25
06/25
ASCEND, NCT05388708: ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment

Recruiting
N/A
550
Europe, Canada, US, RoW
ECMO support, PROSpect protocolized therapies
University of Michigan, National Heart, Lung, and Blood Institute (NHLBI)
Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
09/27
09/27
Kelley-Quon, Lorriane
NCT03730454: Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair

Active, not recruiting
N/A
142
US
Transanastomotic Tube (5FR), No Transanastomotic Tube
Phoenix Children's Hospital
Esophageal Atresia, Tracheoesophageal Fistula
02/25
02/26
Mueller, Claudia
NCT05227599: BRAVE: Building Resilience and Values Through E-health

Completed
N/A
56
US
Online survey questionnaire
Stanford University
Survivorship
03/22
03/22
NCT03730454: Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair

Active, not recruiting
N/A
142
US
Transanastomotic Tube (5FR), No Transanastomotic Tube
Phoenix Children's Hospital
Esophageal Atresia, Tracheoesophageal Fistula
02/25
02/26
Datoc, Imee
RAFT, NCT03101891: Renal Anhydramnios Fetal Therapy

Active, not recruiting
1
70
US
Serial amnioinfusions with isotonic fluid, Renal Anhydramnios Fetal Therapy (RAFT), Spinal needle, Obstetrics and gynecology needle, Isotonic fluid, Normal saline, Lactated ringers solution
Johns Hopkins University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Anhydramnios, Potter Syndrome, Lung Hypoplasia, Multicystic Dysplastic Kidney, Multicystic Renal Dysplasia, Bilateral, Lower Urinary Tract Obstructive Syndrome, Fetal Renal Anomaly
03/25
02/30
Javier, Nadine
DINER, NCT04678219: A Pilot Study Examining Diet in Primary Sclerosing Cholangitis

Recruiting
N/A
20
US
Dietary Intervention
Brigham and Women's Hospital, University of California, Davis, Massachusetts General Hospital
Primary Sclerosing Cholangitis
08/21
12/21
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Bennett, Dave
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Rinsky, Larry
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Vorhies, John
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Imrie, Meghan
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Tileston, Kali
NCT06035952: Study of 3D Scanning for Adolescent Scoliosis

Recruiting
N/A
70
US
3D topographical scan
NSite Medical
Scoliosis
10/23
12/23
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
NCT05697939: 3D Body Surface Modeling for Scoliosis Monitoring

Recruiting
N/A
13
US
NSite 3D Scanning
Stanford University
Adolescent Idiopathic Scoliosis
01/30
01/30
Policy, James
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Ansari, Jessica
CALBLOC, NCT05027048: Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery

Completed
3
120
US
Calcium chloride, Saline placebo
Stanford University, Foundation for Anesthesia Education and Research, Society for Obstetric Anesthesia and Perinatology
Uterine Atony, Uterine Atony With Hemorrhage, Postpartum Hemorrhage, Cesarean Section Complications
03/23
04/23
NCT05973747: Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients

Completed
1
34
US
Calcium Gluconate, Calcium chloride
Stanford University
Postpartum Hemorrhage, Pregnancy Related, Hypocalcemia, Parturition Complication
12/23
12/23
NCT06650930: Pharmacokinetics of Oral Calcium Carbonate in Parturients

Not yet recruiting
1
60
US
Oral calcium carbonate
Stanford University
Pregnancy, Pharmacokinetics, Postpartum Hemorrhage
08/25
10/25
Balili, Rachelle
NCT05608460: Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study

Recruiting
N/A
15700
US
University of Utah
Cervical Spine Fracture
08/25
08/25
Bryson, Xochitl
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Hammer, Gregory
ANA01, NCT03427736: Anesthetics and Analgesics in Children

Recruiting
N/A
460
Canada, US
Ketorolac Tromethamine, Toradol, Hydromorphone, Hydromorphone hydrochloride, Dilaudid, Ketamine, Ketamine Hydrochloride, Oxycodone, Oxycodone Hydrochloride, Morphine, Morphine Sulfate
Kanecia Obie Zimmerman, The Emmes Company, LLC
Anesthesia, Pain
06/25
06/25
Lee, Christine H
DPPOS, NCT00038727: Diabetes Prevention Program Outcomes Study

Active, not recruiting
3
2779
US
DPPOS Group Lifestyle, Metformin, Glucophage, DPPOS Boost Lifestyle, Intensive Lifestyle Group Session, Intensive lifestyle session (ILS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Aging (NIA), National Institute on Minority Health and Health Disparities (NIMHD), National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI), National Eye Institute (NEI), National Center for Research Resources (NCRR), Office of Research on Women's Health (ORWH), Centers for Disease Control and Prevention, American Diabetes Association, Indian Health Service, General Clinical Research Program, US Department of Veterans Affairs
Diabetes Mellitus, Cancer, CVD
10/24
01/25
ENGOT-EN20, NCT05611931 / 2022-002540-42: Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

Jul 2024 - Dec 2024: Top-line data from XPORT-EC trial in participants with TP53 wild type endometrial cancer
Recruiting
3
220
Europe, Canada, US, RoW
Selinexor, KPT-330, Matching Placebo for selinexor
Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group
Endometrial Cancer
01/25
01/28
RAMP 301, NCT06072781: A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Recruiting
3
270
Europe, Canada, US, RoW
avutometinib, avutometinib (VS-6766), Defactinib, defactinib (VS-6063), Pegylated liposomal doxorubicin, Caelyx, Doxil, Lipodox, Paclitaxel, Nov-Onxol, Onxol, Navaplus, Taxol, Letrozole, Femara, Anastrozole, Arimidex
Verastem, Inc., GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Australia New Zealand Gynaecological Oncology Group, Korean Gynecologic Oncology Group
Low Grade Serous Ovarian Cancer
10/28
02/31
REFRaME-O1, NCT05870748: A Study to Investigate the Efficacy and Safety of Luveltamab Tazevibulin Versus Investigator's Choice (IC) Chemotherapy in Women With Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing FOLR1

Recruiting
2/3
600
Canada, US, RoW
Luveltamab tazevibulin, STRO-002, Luvelta, Pegfilgrastim, Neulasta, Gemcitabine, Paclitaxel, Pegylated liposomal doxorubicin, Topotecan
Sutro Biopharma, Inc., GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Asia-Pacific Gynecologic Oncology Trials Group (APGOT)
Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, Platinum-resistant Ovarian Cancer
08/27
02/28
TETON, NCT04814108: A Study of ZN-c3 in Women With Recurrent or Persistent Uterine Serous Carcinoma

Recruiting
2
76
Canada, US, RoW
ZN-c3, azenosertib, KP-2638
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Uterine Serous Carcinoma
11/24
05/25
PROFECTA-II, NCT04374630: Study with Afuresertib and Paclitaxel in Platinum Resistant Ovarian

Completed
2
150
US, RoW
Paclitaxel, Afuresertib, LAE002
Laekna Limited
Platinum-resistant Ovarian Cancer
07/23
06/24
PICCOLO, NCT05041257: Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers

Hourglass Oct 2024 - Dec 2024 : Approval for 2L+ FRα +ve PROC
Hourglass Jan 2024 - Jun 2024 : FDA action date for approval for ovarian cancer with high FRAC
Hourglass Jan 2024 - Jun 2024 : sBLA approval for ovarian cancer
Hourglass Jan 2023 - Dec 2023 : ORR data from PICCOLO trial for platinum sensitive ovarian cancer
Completed
2
79
Europe, Canada, US, RoW
Mirvetuximab soravtansine, MIRV, IMGN853
AbbVie
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
01/24
12/24
ENGOT-ov60, NCT04625270 / 2020-004264-26: A Study of Avutometinib (VS-6766) V. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer with and Without a KRAS Mutation

Active, not recruiting
2
225
Europe, Canada, US
avutometinib (VS-6766), avutometinib (VS-6766) and defactinib, avutometinib (VS-6766) and VS-6063
Verastem, Inc., European Network of Gynaecological Oncological Trial Groups (ENGOT), GOG Foundation
Low Grade Ovarian Serous Adenocarcinoma, Ovarian Cancer
11/24
12/26
NCT04202211: FMT for Remission of Active Ulcerative Colitis in Adults

Withdrawn
2
145
Canada
FMT oral, FMT enema, Placebo oral, Placebo enema
University of British Columbia, Crohn's and Colitis Canada
Ulcerative Colitis, Inflammatory Bowel Diseases
12/24
12/28
PRESERVE-004, NCT05446298: ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer

Active, not recruiting
2
58
US
ONC-392, A humanized anti-CTLA4 IgG1 monoclonal antibody made by OncoC4, Inc., Pembrolizumab, MK3475, Keytruda
OncoC4, Inc., Merck Sharp & Dohme LLC, GOG Foundation
Ovarian Cancer, High Grade Serous Adenocarcinoma of Ovary, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
06/25
06/26
UTMOST2, NCT06999798: An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The Trial

Not yet recruiting
2
20
US
Diagnostic Mammography, diagnostic mammogram, Resection, Surgical Resection, Ultrasound Imaging, 2-Dimensional Grayscale Ultrasound Imaging, 2-Dimensional Ultrasound Imaging, 2D-US, Ultrasonography, Ultrasound, Ultrasound Test, Ultrasound, Medical, US, Twinkling Marker Placement, Twinkle Marker, Mayo Twinkle Marker, Biopsy Twinkle Marker, Biopsy Twinkling Marker, Mayo-designed Twinkling Marker
Mayo Clinic, National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Locally Advanced Breast Carcinoma
07/26
07/26
NCT03806803: Multicentre Blinded Comparison of Lyophilized Sterile Fecal Filtrate to Lyophilized Fecal Microbiota Transplant in Recurrent Clostridioides Difficile Infection

Completed
2
138
Canada
Lyophilized fecal microbiota transplant, Lyophilized sterile fecal filtrate
University of Alberta, University of British Columbia, University of Calgary, McGill University
Clostridia Difficile Colitis, Clostridium Difficile Diarrhea
03/24
03/24
CASTLE, NCT05613946: Contrast-Enhanced Ultrasound and Shear Wave Elastography for the Treatment of Lymphedema

Completed
1
26
US
Lumason, sulfur hexafluoride lipid-type A microspheres, Optison, perflutren protein-type A microspheres, Definity, perflutren lipid microsphere
Mayo Clinic
Lymphedema Arm
06/24
06/24
AMPS, NCT04213846: Alcohol & Mobile Phone Study to Reduce High-risk Alcohol Use and Consequences

Completed
N/A
408
US
Experimental: Mobile Alcohol Expectancy Intervention
University of Washington, National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol; Use, Problem
04/22
04/22
NCT06441188: Sonography of the Nipple Areolar Complex

Completed
N/A
20
US
Thin layer conventional ultrasound coupling gel, Thick layer of conventional ultrasound coupling gel, Thin conventional ultrasound coupling gel pad, Thick conventional ultrasound coupling gel pad
Mayo Clinic
Healthy
10/24
10/24
NCT05547347: Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients with Locally Advanced Breast Cancer

Enrolling by invitation
N/A
15
US
Magnetic Resonance Imaging, Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, Mammogram, Ultrasound, Ultrasound-Guided Biopsy, Ultrasound Guided Biopsy, Twinkle marker
Mayo Clinic, National Cancer Institute (NCI)
Anatomic Stage III Breast Cancer AJCC V8, Locally Advanced Breast Carcinoma, Resectable Breast Carcinoma
12/25
12/25
NCT04692818: 3D Ultrasound Breast Imaging

Recruiting
N/A
125
US
GE Logiq E10 clinical ultrasound scanner, Verasonics research scanner
Mayo Clinic, United States Department of Defense
Breast Tumor
12/25
12/26
NCT06873802: ZTE MRI Pulse Sequence Use for Visualization of Bone Cement, Breast Biopsy Markers

Recruiting
N/A
20
US
Non-Interventional Study
Mayo Clinic, National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Breast Carcinoma
12/25
12/25
FETO, NCT05461222: Fetal Endoscopic Tracheal Occlusion () for Severe Congenital Diaphragmatic Hernia

Recruiting
N/A
15
US
Balt "Goldballoon"
Yair Blumenfeld
Congenital Diaphragmatic Hernia
08/25
08/27
NCT07011615: Feasibility/Acceptability of a Brief Motivational Intervention for Frequent/High-Intensity Cannabis Use

Not yet recruiting
N/A
120
NA
Brief Motivational Mobile Health (mHealth) Intervention, Psychoeducational Attention Control (AC)
University of Washington, National Institute on Drug Abuse (NIDA)
Cannabis Use
09/26
09/26
ROCC, NCT04831580: A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

Recruiting
N/A
840
Canada, US
da Vinci, open surgery
GOG Foundation, Intuitive Foundation
Cervical Cancer
08/28
08/29
Shew, Stephen B
NCT03730454: Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair

Active, not recruiting
N/A
142
US
Transanastomotic Tube (5FR), No Transanastomotic Tube
Phoenix Children's Hospital
Esophageal Atresia, Tracheoesophageal Fistula
02/25
02/26
Newton, Peter
NCT04058561: Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals

Active, not recruiting
N/A
210
Europe, Canada, US, RoW
MAGEC® Spinal Bracing And Distraction System
Pediatric Spine Foundation, Columbia University
Early-Onset Scoliosis Deformity of Spine
12/27
12/27
NCT01661959: Adolescent Idiopathic Scoliosis Outcomes Database Registry

Enrolling by invitation
N/A
10000
Canada, US
Setting Scoliosis Straight Foundation, DePuy Spine, NuVasive
Adolescent Idiopathic Scoliosis
12/25
12/25
PCPS, NCT00680264: Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy

Recruiting
N/A
402
Canada, US
Setting Scoliosis Straight Foundation, K2M, Inc.
Cerebral Palsy, Scoliosis
12/25
12/25
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
NCT04505579: The Tether™ - Vertebral Body Tethering System Post Approval Study

Recruiting
N/A
200
US
Anterior Vertebral Body Tethering, AVBT
ZimVie, Setting Scoliosis Straight Foundation, Exponent, Inc.
Scoliosis Idiopathic
08/27
12/27
NCT02434003: Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis

Recruiting
N/A
1200
Europe, Canada, Japan, US, RoW
St. Justine's Hospital, Queen Mary Hospital, Hong Kong, The Meijo Hospital, Nagoya, Japan, National University of Singapore, Hopital Universitaire Robert-Debre, Alfred I. duPont Hospital for Children, Nicklaus Children's Hospital f/k/a Miami Children's Hospital, Rady Children's Hospital, San Diego
Scoliosis
12/27
12/27
Carvalho, Brendan
NCT05488457: Oxytocin Pharmacokinetics and Pharmacodynamics

Recruiting
2
100
US
deuterated oxytocin (d5OT), Deuterium-labeled oxytocin
University of Chicago, Stanford University
Post Partum Hemorrhage, Cesarean Section Complications, Blood Loss
09/25
12/25
NCT04749043: Virtual Reality Compared to Nitrous Oxide for Labor Analgesia

Completed
N/A
20
US
Oculus Quest 2 Virtual Reality Device, Nitrous oxide
Brendan Carvalho
Labor Pain
12/23
12/23
NCT03975660: Evaluation of Objective Pain Measurement Device

Completed
N/A
130
US
Pain Measurement Device
Stanford University
Pain, Analgesia, Labor Pain
10/23
10/23
NCT06030063: The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

Recruiting
N/A
5000
Canada, US
Yale University
Cesarean Delivery, General Anesthesia
09/28
09/29
Sultan, Pervez
NCT05065203: Evaluation of Inpatient Sleep and Activity Following Childbirth

Completed
N/A
78
US
planned or unplanned Cesarean, operative, or non operative delivery
Stanford University
Sleep
09/22
01/23
NCT04358757: Immune and Physical Recovery Following Cesarean Delivery

Completed
N/A
60
US
Elective cesarean delivery
Stanford University
Cesarean Delivery
09/23
12/23
Daldrup-Link, Heike
NCT02893293: Imaging of Osteonecrosis With Ferumoxytol-Enhanced MRI

Completed
4
14
US
Ferumoxytol-enhanced magnetic resonance imaging, Magentic Resonance Imaging, MRI
Stanford University
Osteonecrosis
10/23
10/23
NCT01336803: Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI

Completed
2
32
US
Feraheme, ferumoxytol, Magnetic Resonance Imaging (MRI) scan, Magnetic Resonance (MR) scan
Heike E Daldrup-Link
Bone Cancer, Chondrosarcoma, Ewing's Sarcoma, Osteosarcoma, Rhabdomyosarcoma, Bone Necrosis, Bone Sarcoma, Osteomyelitis
07/14
10/23
NCT01542879: Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer

Recruiting
1/2
75
US
WB-DW-MR scan, Whole Body Diffusion Weighted MR scan, 18-F-FDG PET scan, Fludeoxyglucose PET scan, Ferumoxytol, feraheme, 18-F-FDG PET/MR scan
Heike E Daldrup-Link
Cancer
10/25
12/26
NCT03458520: Pediatric PET/MR Image Registry

Recruiting
N/A
100
US
PET/MR imaging, positron emission tomography, MR imaging, magnetic resonance imaging, PET/CT imaging, computed tomography
Stanford University, National Cancer Institute (NCI)
Soft Tissue, Lymphoma, Osteosarcoma
09/25
09/25
Enns, Gregory M
NCT05099640 / 2021-000474-29: A Study of PTC923 in Participants With Phenylketonuria

Completed
3
157
Europe, Canada, US, RoW
PTC923, Placebo
PTC Therapeutics
Phenylketonuria
04/23
05/23
SYNPHENY-3, NCT05764239: Efficacy and Safety of SYNB1934 in Patients With PKU

Terminated
3
35
Canada, US, RoW
SYNB1934v1, Placebo
Synlogic
Phenylketonuria
03/24
03/24
NCT05166161 / 2021-000497-28: A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria

Recruiting
3
200
Europe, Canada, Japan, US, RoW
PTC923, Sepiapterin
PTC Therapeutics
Phenylketonuria
04/26
04/26
NCT01370447: EPI-743 for Mitochondrial Respiratory Chain Diseases

No Longer Available
2
94
US
EPI-743, Vincerinone, Vatiquinone
PTC Therapeutics
Mitochondrial Diseases
 
 
NCT00237315: Longitudinal Study of Urea Cycle Disorders

Recruiting
N/A
1500
Europe, Canada, US
Andrea Gropman, National Center for Research Resources (NCRR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Rare Diseases Clinical Research Network
Brain Diseases, Metabolic, Inborn, Amino Acid Metabolism, Inborn Errors, Urea Cycle Disorders
07/25
07/26
NAMDC, NCT01694940: North American Mitochondrial Disease Consortium Patient Registry and Biorepository

Recruiting
N/A
1000
Canada, US
Columbia University, National Institute of Neurological Disorders and Stroke (NINDS)
Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
12/25
12/25
NCT03115086: The REPLACE Registry for Cholbam® (Cholic Acid)

Active, not recruiting
N/A
55
US
Cholbam
Mirum Pharmaceuticals, Inc.
Bile Acid Synthesis Disorders
07/38
07/39
Naviaux, Robert
NAMDC, NCT01694940: North American Mitochondrial Disease Consortium Patient Registry and Biorepository

Recruiting
N/A
1000
Canada, US
Columbia University, National Institute of Neurological Disorders and Stroke (NINDS)
Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
12/25
12/25
Muehe, Anne
NCT01542879: Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer

Recruiting
1/2
75
US
WB-DW-MR scan, Whole Body Diffusion Weighted MR scan, 18-F-FDG PET scan, Fludeoxyglucose PET scan, Ferumoxytol, feraheme, 18-F-FDG PET/MR scan
Heike E Daldrup-Link
Cancer
10/25
12/26
NCT03458520: Pediatric PET/MR Image Registry

Recruiting
N/A
100
US
PET/MR imaging, positron emission tomography, MR imaging, magnetic resonance imaging, PET/CT imaging, computed tomography
Stanford University, National Cancer Institute (NCI)
Soft Tissue, Lymphoma, Osteosarcoma
09/25
09/25
Blumenfeld, Yair
RAFT, NCT03101891: Renal Anhydramnios Fetal Therapy

Active, not recruiting
1
70
US
Serial amnioinfusions with isotonic fluid, Renal Anhydramnios Fetal Therapy (RAFT), Spinal needle, Obstetrics and gynecology needle, Isotonic fluid, Normal saline, Lactated ringers solution
Johns Hopkins University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Anhydramnios, Potter Syndrome, Lung Hypoplasia, Multicystic Dysplastic Kidney, Multicystic Renal Dysplasia, Bilateral, Lower Urinary Tract Obstructive Syndrome, Fetal Renal Anomaly
03/25
02/30
FETO, NCT05461222: Fetal Endoscopic Tracheal Occlusion () for Severe Congenital Diaphragmatic Hernia

Recruiting
N/A
15
US
Balt "Goldballoon"
Yair Blumenfeld
Congenital Diaphragmatic Hernia
08/25
08/27
NCT02774746: Gastroschisis Outcomes of Delivery (GOOD) Study

Recruiting
N/A
800
US
35-week delivery, 38-week delivery
Medical College of Wisconsin
Gastroschisis
03/27
03/27
Chao, Stephanie D
REACT-AF, NCT05836987: The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Recruiting
3
5350
US
AFSW Guided DOAC, Apple Watch, Continuous DOAC therapy, Oral Anticoagulation therapy
Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI)
Atrial Fibrillation
07/29
07/29
NCT05608460: Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study

Recruiting
N/A
15700
US
University of Utah
Cervical Spine Fracture
08/25
08/25
Meyer, Marisa
ANA01, NCT03427736: Anesthetics and Analgesics in Children

Recruiting
N/A
460
Canada, US
Ketorolac Tromethamine, Toradol, Hydromorphone, Hydromorphone hydrochloride, Dilaudid, Ketamine, Ketamine Hydrochloride, Oxycodone, Oxycodone Hydrochloride, Morphine, Morphine Sulfate
Kanecia Obie Zimmerman, The Emmes Company, LLC
Anesthesia, Pain
06/25
06/25
ASCEND, NCT05388708: ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment

Recruiting
N/A
550
Europe, Canada, US, RoW
ECMO support, PROSpect protocolized therapies
University of Michigan, National Heart, Lung, and Blood Institute (NHLBI)
Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
09/27
09/27
Kelley-Quon, Lorriane
NCT03730454: Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair

Active, not recruiting
N/A
142
US
Transanastomotic Tube (5FR), No Transanastomotic Tube
Phoenix Children's Hospital
Esophageal Atresia, Tracheoesophageal Fistula
02/25
02/26
Mueller, Claudia
NCT05227599: BRAVE: Building Resilience and Values Through E-health

Completed
N/A
56
US
Online survey questionnaire
Stanford University
Survivorship
03/22
03/22
NCT03730454: Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair

Active, not recruiting
N/A
142
US
Transanastomotic Tube (5FR), No Transanastomotic Tube
Phoenix Children's Hospital
Esophageal Atresia, Tracheoesophageal Fistula
02/25
02/26
Datoc, Imee
RAFT, NCT03101891: Renal Anhydramnios Fetal Therapy

Active, not recruiting
1
70
US
Serial amnioinfusions with isotonic fluid, Renal Anhydramnios Fetal Therapy (RAFT), Spinal needle, Obstetrics and gynecology needle, Isotonic fluid, Normal saline, Lactated ringers solution
Johns Hopkins University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Anhydramnios, Potter Syndrome, Lung Hypoplasia, Multicystic Dysplastic Kidney, Multicystic Renal Dysplasia, Bilateral, Lower Urinary Tract Obstructive Syndrome, Fetal Renal Anomaly
03/25
02/30
Javier, Nadine
DINER, NCT04678219: A Pilot Study Examining Diet in Primary Sclerosing Cholangitis

Recruiting
N/A
20
US
Dietary Intervention
Brigham and Women's Hospital, University of California, Davis, Massachusetts General Hospital
Primary Sclerosing Cholangitis
08/21
12/21
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Bennett, Dave
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Rinsky, Larry
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Vorhies, John
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Imrie, Meghan
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Tileston, Kali
NCT06035952: Study of 3D Scanning for Adolescent Scoliosis

Recruiting
N/A
70
US
3D topographical scan
NSite Medical
Scoliosis
10/23
12/23
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
NCT05697939: 3D Body Surface Modeling for Scoliosis Monitoring

Recruiting
N/A
13
US
NSite 3D Scanning
Stanford University
Adolescent Idiopathic Scoliosis
01/30
01/30
Policy, James
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30
Ansari, Jessica
CALBLOC, NCT05027048: Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery

Completed
3
120
US
Calcium chloride, Saline placebo
Stanford University, Foundation for Anesthesia Education and Research, Society for Obstetric Anesthesia and Perinatology
Uterine Atony, Uterine Atony With Hemorrhage, Postpartum Hemorrhage, Cesarean Section Complications
03/23
04/23
NCT05973747: Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients

Completed
1
34
US
Calcium Gluconate, Calcium chloride
Stanford University
Postpartum Hemorrhage, Pregnancy Related, Hypocalcemia, Parturition Complication
12/23
12/23
NCT06650930: Pharmacokinetics of Oral Calcium Carbonate in Parturients

Not yet recruiting
1
60
US
Oral calcium carbonate
Stanford University
Pregnancy, Pharmacokinetics, Postpartum Hemorrhage
08/25
10/25
Balili, Rachelle
NCT05608460: Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study

Recruiting
N/A
15700
US
University of Utah
Cervical Spine Fracture
08/25
08/25
Bryson, Xochitl
NCT04296903: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Active, not recruiting
N/A
200
US
MID-C System
Apifix
Adolescent Idiopathic Scoliosis
06/29
06/30

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