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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Witte, Klaus K
NCT03781427: Tailoring Pacemaker Output to Physiology in Chronic Heart Failure	Recruiting	3	70	Europe	Cardiac resynchronization therapy	University of Leeds	Chronic Heart Failure	07/23	08/23
OPT-cont 2, NCT04201015: Optimising Pacing for Contractility 2	Recruiting	2/3	400	Europe	Heart rate optimisation using force frequency data	University of Leeds	Heart Failure, Systolic, Pacemaker	12/24	03/25
NCT04332536: Limitations of Aerobic Capacity in Chronic Heart Failure	Completed	N/A	91	Europe	Exercise with and without Codeine	University of Leeds	Chronic Heart Failure	08/24	10/24
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR	Recruiting	N/A	300	Europe, US	Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication	Cardiac Dimensions, Inc.	Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases	12/26	12/30
Jamil, Haqeel A
EASY-AS, NCT04204915: The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study	Recruiting	N/A	2844	Europe, RoW	Aortic valve replacement	University of Leicester, University of Auckland, New Zealand, University Hospitals, Leicester, The University of Western Australia	Aortic Stenosis	04/31	04/31
Gierula, John
OPT-cont 2, NCT04201015: Optimising Pacing for Contractility 2	Recruiting	2/3	400	Europe	Heart rate optimisation using force frequency data	University of Leeds	Heart Failure, Systolic, Pacemaker	12/24	03/25