| Waddell, Thomas |
SORT, NCT05183932: Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer |
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| Recruiting | N/A | 440 | Canada, US | | Washington University School of Medicine, National Cancer Institute (NCI) | Non Small Cell Lung Cancer, Non-small Cell Lung Cancer | 01/27 | 01/27 | | |
| Ha, Andrew |
| Recruiting | 4 | 396 | Canada | a wearable adhesive cardiac monitoring device | St. Michael's Hospital, Toronto, Southlake Regional Health Centre, University Health Network, Toronto | Cardiac Arrhythmias, Atrial Fibrillation | 12/20 | 12/20 | | |
| Active, not recruiting | 3 | 700 | Europe, Canada, US, RoW | Implantable Cardioverter Defibrillator + Usual Care, Implantable Cardioverter Defibrillator, ICD, Usual care, Standard medical therapy alone | University of Calgary, Canadian Institutes of Health Research (CIHR), Alberta Innovation and Science, Medtronic, GE Healthcare, Cardiac Arrhythmia Network of Canada, Accelerating Clinical Trials Consortium | Myocardial Infarction, Sudden Death | 12/24 | 12/24 | | |
| Recruiting | 3 | 194 | Europe, Canada, Japan, US | Prednisone or Prednisolone, Methotrexate | Ottawa Heart Institute Research Corporation, Canadian Institutes of Health Research (CIHR) | Cardiac Sarcoidosis, Sarcoidosis | 12/25 | 12/25 | | |
| Recruiting | N/A | 311 | Canada | | Anthony Tang | Atrial Fibrillation, Heart Failure | 09/24 | 09/24 | | |
| Recruiting | N/A | 1500 | Canada, Japan | | Ottawa Heart Institute Research Corporation, Ontario Ministry of Health and Long Term Care, Canadian Institutes of Health Research (CIHR) | Cardiac Sarcoidosis | 12/25 | 12/25 | | |
| David, Shukri |
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN |
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| Recruiting | N/A | 1400 | Europe, US, RoW | Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation | Medtronic Vascular | Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus | 11/26 | 11/29 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
| Perrot, Marc De |
SUPER, NCT06331455: Treatment of Pulmonary SUlcus, Pancoast and Chest Wall Non-small Cell Lung Cancer Employing Radiation, Immuno-oncology and Resection |
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| Recruiting | 2 | 12 | Canada | Durvalumab, Non-ablative oligofractionated radiation (NORT) | Marc de Perrot, Ozmosis Research Inc. | Lung Cancer Patients, Non-small Cell Lung Cancer (NSCLC) | 12/25 | 04/26 | | |
| Not yet recruiting | 2 | 10 | NA | Durvalumab, Non-ablative oligofractionated radiation (NORT) | University Health Network, Toronto, OICR | Non-Small Cell Lung Cancer (NSCLC), Clinical Staging T2b-3 N0-1 M0 | 03/25 | 12/25 | | |
NORTh STAR, NCT04782752: Non-ablative Oligofractionated Radiation Therapy Before Surgical Transplantation As Radiovaccination |
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| Recruiting | N/A | 42 | Canada | Radiation: Varying Doses of RT | University Health Network, Toronto | Transplant-Related Lung Cancer | 12/25 | 12/25 | | |
| Schimmel, Melanee |
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN |
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| Recruiting | N/A | 1400 | Europe, US, RoW | Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation | Medtronic Vascular | Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus | 11/26 | 11/29 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
ECLIPSE, NCT03108456: Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The Trial |
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| Active, not recruiting | N/A | 2005 | US | Orbital Atherectomy, Balloon | Abbott Medical Devices, Cardiovascular Research Foundation, New York | Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction | 06/24 | 06/25 | | |
| Active, not recruiting | N/A | 300 | US | Renal Denervation | ReCor Medical, Inc. | Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases | 12/28 | 12/28 | | |
| Abidov, Yulia |
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN |
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| Recruiting | N/A | 1400 | Europe, US, RoW | Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation | Medtronic Vascular | Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus | 11/26 | 11/29 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
