Wuhan Union Hospital, Tongji Medical College (TJMC), Huazhong University of Science and Technology (HUST)
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 42 Trials 
90 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Li, Wei
NCT04201808: Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides

Recruiting
4
100
RoW
Tenofovir Alafenamide 25 MG, Vemlidy
New Discovery LLC, Beijing Ditan Hospital
Hepatitis B, Chronic
09/23
09/23
CSPPT2-TT, NCT04974151: China Stroke Primary Prevention Trial 2 for Participants with Hypertension and MTHFR 677 TT Genotype

Recruiting
4
24000
RoW
Amlodipine besylate, Amlodipine, Amlodipine besylate And Folic Acid, Amlodipine Folic Acid, Anye, 5-methyltetrahydrofolate (5-MTHF), 5-MTHF, Amlodipine placebo, Amlodipine (dummy), Amlodipine folic acid placebo, Amlodipine folic acid (dummy), 5-MTHF Placebos, 5-MTHF (dummy)
Shenzhen Ausa Pharmed Co.,Ltd, Peking University First Hospital, Second Affiliated Hospital of Nanchang University, The First People's Hospital of Lianyungang, The Affiliated Hospital Of Guizhou Medical University, Lianyungang Oriental Hospital, Tengzhou Central People's Hospital, First Affiliated Hospital Bengbu Medical College, H & J CRO International, Inc., Shenzhen Prospective Medical Technology Co., LTD
Hypertension, MTHFR 677 TT Genotype
06/29
06/29
CSPPT2-CC/CT, NCT04974138: China Stroke Primary Prevention Trial 2 for Participants with H-type Hypertension and MTHFR 677 CC/CT Genotype

Recruiting
4
32000
RoW
Amlodipine besylate, Amlodipine, Amlodipine besylate and folic acid, Amlodipine folic acid, Anye, Amlodipine placebos, Amlodipine (dummy), Amlodipine-folic acid placebos, Amlodipine-folic acid (dummy)
Shenzhen Ausa Pharmed Co.,Ltd, Peking University First Hospital, Second Affiliated Hospital of Nanchang University, The First People's Hospital of Lianyungang, The Affiliated Hospital Of Guizhou Medical University, Lianyungang Oriental Hospital, Tengzhou Central People's Hospital, First Affiliated Hospital Bengbu Medical College, H & J CRO International, Inc., Shenzhen Prospective Medical Technology Co., LTD
Hypertension, MTHFR 677 CC or CT Genotype, Elevated Plasma Homocysteine (Hcy≥10µmol/L), Insufficient Plasma Folate Levels (<12ng/mL)
06/29
06/29
NCT03236649: The Phase III Study of Icaritin Versus Sorafenib in PD-L1 Positive Advanced Hepatocellular Carcinoma Subjects

Terminated
3
89
RoW
Icaritin, Sorafenib Tosylate Tablets
Beijing Shenogen Biomedical Co., Ltd, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Eastern Theater General Hospital,QinHuai District Medical Area, Peking University Cancer Hospital & Institute, Chinese PLA General Hospital, Beijing Hospital, General Hospital of Chinese Armed Police Forces, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Jinan Central Hospital, Linyi Cancer Hospital, The First Affiliated Hospital of Anhui Medical University, Anhui Provincial Hospital, The First Affiliated Hospital with Nanjing Medical University, The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China, Nanfang Hospital of Southern Medical University, First People's Hospital of Foshan, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Tianjin Medical University Cancer Institute and Hospital, The Fourth Hospital of Hebei Medical University, Hunan Cancer Hospital, The First Hospital of Jilin University, 307 Hospital of PLA, Fudan University, Henan Cancer Hospital, Jilin Provincial Tumor Hospital, First Affiliated Hospital of Harbin Medical University, First Affiliated Hospital Bengbu Medical College, The First Affiliated Hospital of Soochow University, Tongji Hospital, Beijing YouAn Hospital
Hepatocellular Carcinoma (HCC)
02/22
02/22
TQB2450-III-08, NCT04809142: A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule as Second-line Treatment in Subjects With Advanced Biliary Cancer

Recruiting
3
392
RoW
TQB2450 Injection, Anlotinib hydrochloride, Oxaliplatin injection, Capecitabine tablets, Gemcitabine hydrochloride injection
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Advanced Biliary Cancer
03/22
02/23
TQB2450-III-06, NCT04405505: A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule Versus Paclitaxel for Injection (Albumin Bound) in Subjects With Triple Negative Breast Cancer (TNBC)

Not yet recruiting
3
332
RoW
TQB2450, Anlotinib, Paclitaxel for Injection (albumin bound)
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Triple Negative Breast Cancer
07/22
07/22
NCT03236636: The Phase III Study of Icaritin Versus HUACHANSU PIAN in Hepatocellular Carcinoma Subjects

Recruiting
3
312
RoW
Icaritin, SNG-162, HUACHANSU PIAN, HUACHANSU PIAN(999)
Beijing Shenogen Biomedical Co., Ltd, Chinese Academy of Medical Sciences, NanJing PLA 81 Hospital, Peking University Cancer Hospital & Institute, Beijing Hospital, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Jinan Central Hospital, Linyi Tumour Hospital, The First Affiliated Hospital of Anhui Medical University, Anhui Provincial Hospital, The First Affiliated Hospital with Nanjing Medical University, The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China, Nanfang Hospital of Southern Medical University, First People's Hospital of Foshan, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Hebei Medical University Fourth Hospital, The First Hospital of Jilin University, Haikou People's Hospital, Fudan University, West China Hospital, Chongqing Traditional Chinese Medicine Hospital, Chifeng Municipal Hospital, The Affiliated Hospital of Hangzhou Normal University, The First Affiliated Hospital of Zhengzhou University, Guilin Medical University, China, The Third Xiangya Hospital of Central South University, Yunnan Provincial Hospital of Traditional Chinese Medicine, The Sixth People's Hospital of Shenyang
Advanced HBV-Related Hepatocellular Carcinoma (HCC)
12/22
12/22
RC48-C012, NCT04400695: A Study of RC48-ADC for the Treatment of Locally Advanced or Metastatic Breast Cancer With Low Expression of HER2

Recruiting
3
366
RoW
RC48-ADC, RC48, Paclitaxel Injection, Taxol, Docetaxel Injection, Taxotere, Vinorelbine Tartrate Injection, Navelbine, Capecitabine Tablets, Xeloda
RemeGen Co., Ltd.
Breast Cancer
06/24
12/24
NCT04222114: Comparing the Efficacy and Safety of Intra-peritoneal Infusion of Catumaxomab and Treatment of Investigator Choice in Patients With Advanced Gastric Carcinoma With Peritoneal Metastasis

Recruiting
3
282
RoW
Catumaxomab, The treatment of investigator choice
LintonPharm Co.,Ltd.
Stomach Neoplasms
03/23
08/23
NCT04851613: Study Evaluating Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients w/ Locally Advanced or Metastatic HR+/HER2- Breast Cancer

Recruiting
3
256
US, RoW
Afuresertib, Fulvestrant, Afuresertib/placebo
Laekna Limited
Breast Cancer
10/26
12/26
NCT04486651: HX008 Plus Irinotecan Versus Placebo Plus Irinotecan as Second-line Treatment in Advanced Gastric Cancer

Recruiting
3
560
RoW
Irinotecan Hydrochloride Injection, HX008, Placebo
Taizhou Hanzhong biomedical co. LTD
Stomach Cancer
08/23
08/23
LEONARDA-1, NCT05054751: GB491 Combined With Fulvestrant for HR+ HER2- Locally Advanced or Metastatic Breast Cancer

Completed
3
275
RoW
GB491+ Fulvestrant, test drug + Fulvestrant, Placebo+Fulvestrant, placebo control + Fulvestrant
Genor Biopharma Co., Ltd.
Locally Advanced or Metastatic Breast Cancer
12/22
03/24
NCT06477237: Study of Efficacy and Safety of HB0017 in Patients With Moderate to Severe Plaque Psoriasis

Recruiting
3
400
RoW
HB0017 Q4W, HB0017 Q8W, placebo
Huabo Biopharm Co., Ltd.
Psoriasis
08/24
12/25
NCT05115942: Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Viral Hepatitis B Phase 3 Trial.

Completed
3
248
RoW
Hydronidone capsules, F351, The placebo capsules, N
Beijing Continent Pharmaceutical Co, Ltd.
Liver Fibrosis
10/24
10/24
EMBER-3, NCT04975308 / 2021-000079-35: A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

Active, not recruiting
3
866
Europe, Japan, US, RoW
Imlunestrant, LY3484356, Exemestane, Fulvestrant, Abemaciclib, LY2835219
Eli Lilly and Company, Eli Lilly and Company
Breast Neoplasms, Neoplasm Metastasis
06/24
08/27
ENREACH-PDAC-01, NCT05149326: KN046 in Subjects With Advanced Pancreatic Ductal Adenocarcinoma.

Active, not recruiting
3
408
RoW
KN046, placebo
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
Advanced Pancreatic Ductal Adenocarcinoma
04/24
08/24
NCT05975268: A Clinical Study to Evaluate the Efficacy and Safety of Subcutaneous JS005 Injection in the Treatment of Adults With Moderate to Severe Chronic Plaque Psoriasis

Active, not recruiting
3
747
RoW
JS005 (recombinant humanized monoclonal antibody against IL-17A)
Shanghai Junshi Bioscience Co., Ltd.
Moderate to Severe Chronic Plaque Psoriasis
08/25
10/25
PANOVA-3, NCT03377491: Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel

Completed
3
571
Europe, Canada, US, RoW
NovoTTF-200T, TTFields, Gemcitabine, nab paclitaxel
NovoCure Ltd.
Pancreas Adenocarcinoma
10/24
10/24
HER2CLIMB-05, NCT05132582 / 2021-002491-39: A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer

Calendar Jan 2025 - Dec 2025: From MOUNTAINEER-02 trial in combination with Herceptin and Cyramza for metastatic HER2+ gastric cancer
Active, not recruiting
3
654
Europe, Canada, Japan, US, RoW
Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo
Seagen Inc., Merck Sharp & Dohme LLC
HER2 Positive Breast Cancer
05/25
10/27
NCT05545137: Clinical Trial of Pivmecillinam Hydrochloride Tablets in the Treatment of Uncomplicated Urinary Tract Infection

Completed
3
299
RoW
Pivmecillinam hydrochloride tablets, Selexid®, Fosfomycin Tromethamine Granules, Monurol®
Benova (Tianjin) Innovative medicine Research Co., Ltd.
Uncomplicated Urinary Tract Infection
02/24
02/24
BALLAD+, NCT05681481 / 2021-003063-10: A Phase 3 Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Efgartigimod PH20 SC in Adult Participants with Bullous Pemphigoid

Active, not recruiting
3
160
Europe, Japan, US, RoW
efgartigimod PH20 SC, Prednisone
argenx, argenx BV
Bullous Pemphigoid
01/26
03/26
LEONARDA-2, NCT05851014: A Study of GB491 in Combination With Letrozole in Patients With HR Positive and HER2 Negative Advanced Breast Cancer

Recruiting
3
350
RoW
GB491 combined with Letrozole, Placebo combined with Letrozole
Genor Biopharma Co., Ltd.
Breast Cancer
01/26
01/27
NCT05905172: Hydronidone Capsules in Long-term Treatment in Patients With Chronic Viral Hepatitis B Liver Fibrosis

Recruiting
3
248
RoW
Hydronidone capsules, F351, The placebo capsules, N
Beijing Continent Pharmaceutical Co, Ltd.
Liver Fibrosis
06/28
10/28
OPTIMAL, NCT03315364 / 2020-000954-86: Oral Paclitaxel Trial In Recurrent and Metastatic Breast Cancer As 1st Line Therapy

Active, not recruiting
2/3
549
Europe, RoW
Oral paclitaxel, Liporaxel®, Paclitaxel injection, Taxol®
Daehwa Pharmaceutical Co., Ltd., Daehwa pharmaceutical Co., Ltd.
Recurrent or Metastatic Breast Cancer
02/24
12/25
RC48-C006, NCT03500380: A Study of RC48-ADC Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer With or Without Liver Metastases

Active, not recruiting
2/3
301
RoW
RC48-ADC, RC48, Lapatinib, Capecitabine
RemeGen Co., Ltd.
Breast Neoplasms, Breast Diseases, Capecitabine, HER2-positive Breast Cancer, HER2 Positive Breast Carcinoma, HER2-positive Advanced Breast With Liver Metastases
07/24
12/24
SPH-B007-303, NCT06447597: A Clinical Study of B007 in the Treatment of Generalized Myasthenia Gravis.

Recruiting
2/3
104
RoW
B007, Placebo
Shanghai Jiaolian Drug Research and Development Co., Ltd, Shanghai Pharmaceuticals Holding Co., Ltd
Generalized Myasthenia Gravis
06/26
06/26
NCT06454357: A Clinical Study of B007 in the Treatment of Pemphigus.

Recruiting
2/3
132
RoW
B007
Shanghai Jiaolian Drug Research and Development Co., Ltd, Shanghai Pharmaceuticals Holding Co., Ltd
Pemphigus
12/26
12/26
NCT04603040: A Study to Evaluate the Efficacy and Safety of Toripalimab Injection in the Treatment of Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy and Are Positive Specific Markers

Recruiting
2
100
RoW
Toripalimab, Tuoyi
Shanghai Junshi Bioscience Co., Ltd.
Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy
12/22
03/23
NCT04329429: A Study of RC48-ADC in Subjects With HER2 Overexpressed Metastatic Biliary Tract Cancer

Active, not recruiting
2
57
RoW
RC48-ADC, Recombinant Humanized anti-HER2 Monoclonal Antibody-MMAE Conjugate For Injection
RemeGen Co., Ltd.
Biliary Tract Cancer
11/23
06/24
NCT05145907: Study to Evaluate Safety and Efficacy of TJ107 Combine With PD-1 in Patients With Solid Tumors

Active, not recruiting
2
133
RoW
TJ107 +Pembrolizumab
TJ Biopharma Co., Ltd.
Triple-negative Breast Cancer, Head and Neck Squamous Cell Carcinoma
06/24
12/24
HERO-KC23, NCT06375707: Efficacy and Safety of Ribociclib in Combination With NSAI Versus Physician's Choice of Chemotherapy Sequential Endocrine Therapy in HR+/HER2- Advanced Breast Cancer

Recruiting
2
144
RoW
physician's choice of chemotherapy sequential Ribociclib combined with NSAI±OFS, Ribociclib combined with NSAI±OFS
The First Affiliated Hospital with Nanjing Medical University, Zhejiang Cancer Hospital
Advanced Breast Cancer
11/25
12/25
NCT05970432: A Clinical Study of TQH2722 Injection in the Treatment of Moderate to Severe Atopic Dermatitis

Recruiting
2
160
RoW
TQH2722 injection 300mg-150mg, TQH2722 injection 600mg-300mg, TQH2722 injection 900mg-450mg, TQH2722 injection matching Placebo
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Atopic Dermatitis
03/24
03/24
NAUTICALCRC, NCT05004350: A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.

Active, not recruiting
2
103
RoW
Encorafenib, Braftovi®, PF-07263896, W0090, LGX818, ONO-7702, Cetuximab, Erbitux®, C225, FOLFIRI, Folinic acid + Fluorouracil + Irinotecan
Pierre Fabre Medicament, Merck KGaA, Darmstadt, Germany
BRAF V600E, Metastatic Colorectal Cancer
12/23
01/25
NCT06543992: Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Methotrexate in Breast Cancer With Leptomeningeal Metastasis

Recruiting
2
22
RoW
Intrathecal Administration of Thiotepa in Combination with Methotrexate via the Ommaya Reservoir
The First Affiliated Hospital with Nanjing Medical University, The Affiliated Brain Hospital of Nanjing Medical University
Leptomeningeal Metastasis of Breast Cancer
12/26
12/26
NCT06656624: Efficacy and Safety of Ribociclib Combined With AI Versus Physician&Amp;#39;s Choice of Chemotherapy Sequential Endocrine Therapy in ER Middle-low-expression/HER2-negative Advanced Breast Cancer (Rachel)

Recruiting
2
190
RoW
Ribociclib combined with AI±OFS, physician's choice of chemotherapy sequential Ribociclib combined with AI±OFS
The First Affiliated Hospital with Nanjing Medical University, Yidu Central Hospital of Weifang, Affiliated Hospital of Jiangnan University, The Affiliated Jiangyin Hospital of Southeast University Medical College
Advanced Breast Cancer
12/25
12/25
NCT04838964: A Study of MRG003 in the Treatment of EGFR-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer

Recruiting
2
80
RoW
MRG003
Shanghai Miracogen Inc.
Advanced or Metastatic Biliary Tract Cancer
10/24
11/24
YH001, NCT05212922: A Study to Evaluate in Combination With Toripalimab in Subjects With Advanced NSCLC and HCC

Withdrawn
2
80
Europe, RoW
YH001 + Toripalimab
Eucure (Beijing) Biopharma Co., Ltd
HCC, NSCLC Stage IIIB, NSCLC Stage IV
12/24
03/25
NCT06001086: A Phase II Clinical Study of Treatment With Disitamb Vedotin Plus Pyrotinib in HER2-positive Early Breast Cancer

Recruiting
2
70
RoW
Disitamb Vedotin ,pyrotinib, Regular Visits
The First Affiliated Hospital with Nanjing Medical University, First Affiliated Hospital of Wenzhou Medical University
Breast Cancer
08/26
12/26
NCT04237805 / 2013-001045-14: A Phase I/II Clinical Study of SAF-189s in Non-small Cell Lung Cancer (NSCLC) Patients

Recruiting
1/2
280
RoW
SAF-189s, foritinib succinate
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
Advanced Cancer, Advanced Solid Tumor, Lung Cancer, Nonsmall Cell
12/22
03/26
NCT05024214: Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors

Recruiting
1/2
170
RoW
Lenvatinib + Envafolimab, Sunitinib
3D Medicines (Sichuan) Co., Ltd.
Solid Tumors, Non-small Cell Lung Cancer, Renal Cell Carcinoma, Hepatocellular Carcinoma
12/24
12/24
TranStar102, NCT04495296: A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors

Recruiting
1/2
320
RoW
TST001, Oxaliplatin, Capecitabine, Paclitaxel, Gemcitabine, Cisplatin, Nivolumab
Suzhou Transcenta Therapeutics Co., Ltd., Bristol-Myers Squibb
Advanced Cancer
02/25
05/25
TRIGGERCD8, NCT06468358: A Study to Evaluate LB1410 in Combination With LB4330 in Patients With Advanced or Metastatic Solid Tumors

Recruiting
1/2
194
RoW
LB1410, LB4330
L & L biopharma Co., Ltd., Shanghai China, Shanghai East Hospital
Solid Tumor
12/26
12/27
ICP-CL-00301, NCT03758664: Clinical Study of ICP-192 in Solid Tumors Patients

Recruiting
1/2
56
RoW
ICP-192
Beijing InnoCare Pharma Tech Co., Ltd.
Solid Tumor
12/24
12/24
NCT05519059: Pelareorep and Paclitaxel Injection in Chinese Patients With Advanced or Metastatic Breast Cancer

Completed
1
15
RoW
Pelareorep, Paclitaxel
Adlai Nortye Biopharma Co., Ltd.
Advanced or Metastatic Breast Cancer
09/22
05/23
NCT03634839: Effects of E-cigarette Flavors on Youth TCORS 2.0

Completed
1
42
US
Flavoring Agents, Cooling flavor, Nicotine, Nicotine concentration
Yale University, National Institute on Drug Abuse (NIDA)
Nicotine Use Disorder
06/23
07/23
2022-BRL-201, NCT05741359: The Safety and Efficacy of BRL-201 in the Treatment of r/r B Lymphocyte Non-Hodgkin Lymphoma

Recruiting
1
18
RoW
CD19-targeted non-viral PD1 site-specific integrated CAR-T cell injection, BRL-201
Bioray Laboratories, Institute of Hematology & Blood Diseases Hospital,Chinese Academy of Medical Sciences, Zhejiang University, Wuhan Union Hospital, China
Non-hodgkin Lymphoma,B Cell
01/24
03/24
NCT05339685: A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer or Other Solid Tumors

Recruiting
1
26
RoW
BL-M02D1
Sichuan Baili Pharmaceutical Co., Ltd., SystImmune Inc., Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.
Breast Cancer
12/24
12/24
NCT05357651: A Study to Assess the Safety and Efficacy of LB1410 in Participants With Advanced Solid Tumor or Lymphoma(Keyplus-001)

Recruiting
1
100
RoW
LB1410
L & L biopharma Co., Ltd., Shanghai China
Solid Tumor, Lymphoma
12/24
03/25
NCT05244551: A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors

Recruiting
1
85
US, RoW
ABSK061
Abbisko Therapeutics Co, Ltd
Solid Tumor
04/25
04/25
NCT05577312: Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia

Enrolling by invitation
1
9
RoW
BRL-101, BRL-101 autologous hematopoietic stem and progenitor cells injection
Bioray Laboratories, First Affiliated Hospital of Guangxi Medical University, Xiangya Hospital of Central South University, Chinese Academy of Medical Sciences, Nanfang Hospital, Southern Medical University
Beta-Thalassemia
08/25
09/26
NCT06015568: Study of MCLA-129 Combined With Befotertinib in the Treatment of Advanced Non-small Cell Lung Cancer With EGFR Sensitive Mutation

Not yet recruiting
1
172
RoW
MCLA-129: 1500mg or 2000mg IV Q2W, Befotertinib: 75 mg or 100 mg Po QD
Betta Pharmaceuticals Co., Ltd.
Non-Small Cell Lung Cancer、EGFR Sensitive Mutation
11/28
07/29
NCT03147014: Cardiovascular Response to Maternal Hyperoxygenation in Fetal Congenital Heart Disease

Recruiting
N/A
600
RoW
Maternal hyperoxygenation
Beijing Anzhen Hospital
Hypoplastic Left Heart Syndrome, Aortic Coarctation, Atrial Septal Aneurysm
12/21
12/22
NCT04307030: Study on AI Recognition System Of Heart Sound In Congenital Heart Disease Screening

Recruiting
N/A
5000
RoW
Heart Auscultation and Echocardiography
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Congenital Heart Disease in Children
12/21
06/23
NCT04469387: Preventive Effect of Limited Decompression on Adjacent Segment Following Posterior Lumbar Interbody Fusion

Recruiting
N/A
200
RoW
Limited decompressions at adjacent segment with asymptomatic pre-existing spinal canal stenosis, Responsible segments fused
Peking University Third Hospital
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degeneration Spine
08/22
08/32
Cryo-InitialAF, NCT04942834: Using Cryoballoon Ablation as Initial Treatment for Persistent Atrial Fibrillation

Recruiting
N/A
286
RoW
Antiarrhythmic drug including Propafenone, Sotalol, Dronedarone and Amiodarone, cryoballoon ablation
Ruijin Hospital
Atrial Fibrillation, Persistent, Arrhythmias, Cardiac
07/25
01/26
NCT05375123: Reference Range for Tissue Motion Tracking of Mitral Annulus Displacement in Chinese Han Singleton Pregnancies

Recruiting
N/A
660
RoW
Ultrasound image acquisition
First Hospital of China Medical University
Pregnancy
06/23
06/24
NCT05547841: Normal Reference Value for Echocardiography in Chinese Han Pregnancies

Recruiting
N/A
680
RoW
Echocardiography acquisition
First Hospital of China Medical University
Pregnancy
08/23
08/24
CNAVS, NCT06192238: China National Study of Adrenal Venous Sampling

Not yet recruiting
N/A
1500
RoW
adrenal venous sampling
Chinese Academy of Medical Sciences, Fuwai Hospital
Hyperaldosteronism
12/26
12/26
NCT05764941: Inetetamab Combined With Pyrotinib and Vinorelbine as First-line to Third-line Treatment for HER2-positive Metastatic Breast Cancer

Recruiting
N/A
100
RoW
Inetetamab, Pyrotinib, Vinorelbine
The First Affiliated Hospital with Nanjing Medical University
Breast Neoplasms
03/24
03/24
CONNECT-AV, NCT04634916: Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

Recruiting
N/A
280
US
EndoAVF Creation
C. R. Bard
Kidney Disease, End-Stage, End-stage Renal Disease, Arteriovenous Fistula
06/26
09/26
NCT05932693: Effect of Different E-cigarette Cooling Flavors on Adults' Sensory Experience TCORS 3.0

Recruiting
N/A
30
US
E-liquid coolant (WS-3, 0.05%), Flavor type, E-liquid coolant (WS-3, 0.1%), E-liquid coolant (WS-3, 0.5%), E-liquid coolant (WS-3, 1.0%), E-liquid coolant (WS-3, 2.0%), E-liquid coolant (menthol, 0.05%), E-liquid coolant (menthol, 0.1%), E-liquid coolant (menthol, 0.5%), E-liquid coolant (menthol, 1.0%), E-liquid coolant (menthol, 2.0%), E-liquid coolant (WS-23, 0.05%), E-liquid coolant (WS-23, 0.1%), E-liquid coolant (WS-23, 0.5%), E-liquid coolant (WS-23, 1.0%), E-liquid coolant (WS-23, 2.0%), E-liquid coolant (WS-23, 4.0%)
Yale University, National Institute on Drug Abuse (NIDA)
E-Cig Use
01/26
01/26
NCT05978752: Clinical Study on Endoscopic Management of GOV1 Esophagogastric Varices

Not yet recruiting
N/A
57
NA
Endoscopic gel embolization of gastric fundus varices and ligation of esophageal varices, Endoscopic gel embolization of gastric fundus varices and sclerotherapy of esophageal varices, Endoscopic gelatinous embolization of gastric varices (esophageal varices not treated)
Second Affiliated Hospital, School of Medicine, Zhejiang University, Jinhua Hospital Affiliated to Zhejiang University, Lanxi People's Hospital, Lishui Country People's Hospital, Shandong Provincial Hospital Affiliated to Shandong First Medical University
Esophageal and Gastric Varices
06/25
11/25
CaRe-ECMO, NCT05035797: Program on ECMO Weaning

Recruiting
N/A
366
RoW
Cardiopulmonary rehabilitation, Usual care
The First Affiliated Hospital with Nanjing Medical University
Critical Illness
06/25
12/25
NCT06015165: Outcomes for Anesthesiologist-Led Care of Analgesic Protocol in Anorectal Surgery

Recruiting
N/A
216
RoW
Analgesia plan for Anes. Group, Anes Group, Analgesia plan for Surg. Group, Surg. Group, Multi-modal analgesia during the surgery, Intraoperative analgesic plan
China-Japan Friendship Hospital
Postoperative Pain
06/25
10/25
NCT05987293: A Single-center, Prospective Study for Mechanism and Risk Factors of Tracheal Tube-related Tongue Injury

Active, not recruiting
N/A
94
RoW
Tracheal tube-tongue pressure is measured using a computerized occlusal analysis system based on T-Scan® technique, suitable for multi-point real-time monitoring of intraoral pressure.
China-Japan Friendship Hospital
Tracheal Tube-related Tongue Injury
08/24
12/25
HeadSOAR, NCT06115707: Head Position After Endovascular Therapy

Recruiting
N/A
1332
RoW
The lying flat (0°-10°) head position for 72 hours, The The head elevation (30°-40°) position for 72 hours
Zhengzhou Yuan
Stroke, Acute, Endovascular Therapy
11/25
04/26
PURE, NCT03225586: Prospective Urban Rural Epidemiology Study

Recruiting
N/A
200000
Europe, Canada, RoW
Population Health Research Institute, Canadian Institutes of Health Research (CIHR), Heart and Stroke Foundation of Ontario
Cardiovascular Diseases, Risk Factor, Cardiovascular, Health Behavior, Environmental Exposure, Lung Diseases, Cancer, Injuries, Renal Disease, Communicable Disease
12/30
12/30
NCT04688437: Correlation Among Standing-sitting Sagittal Spinal Alignment, Paravertebral Muscle and Postoperative Clinical Outcomes in Patients With Adult Degenerative Scoliosis

Not yet recruiting
N/A
200
RoW
standard standing-sitting posteroanterior and lateral whole spine X-ray and lumbar MRI examination
Peking University Third Hospital
Degenerative Scoliosis
12/21
01/24
THALIA-01, NCT05231863: Tyrosine Kinase Inhibitors (TKIs) in Trastuzumab Emtansine (T-DM1) Resistant HER2-positive Metastatic Breast Cancer: A Real-world Study

Recruiting
N/A
100
RoW
TKIs
The First Affiliated Hospital with Nanjing Medical University
Breast Cancer
12/22
12/22
NCT04467944: Effect of Pre-existing Adjacent Segment Degeneration on Long-term Effectiveness After Lumbar Fusion Surgery

Recruiting
N/A
210
RoW
Pre-existing degenerative factors at adjacent segment
Peking University Third Hospital
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degeneration Spine
12/22
12/32
NCT05444647: Gut Microbiome Components Predict Response to Neoadjuvant Therapy in HER2-positive Breast Cancer Patients : A Prospective Study

Recruiting
N/A
100
RoW
stool and blood collection
The First Affiliated Hospital with Nanjing Medical University
Breast Cancer
05/24
06/25
NCT05596864: Transabdominal Gastric Contrast Ultrasound

Not yet recruiting
N/A
1000
NA
gastric contrast ultrasound
The First Hospital of Jilin University
Transabdominal Gastric Contrast Ultrasound
06/24
12/24
ALOT-BC1, NCT05334147: Anlotinib Combined With Chemotherapy for the Treatment of HER2 Negative Advanced Breast Cancer

Not yet recruiting
N/A
315
NA
The First Affiliated Hospital with Nanjing Medical University
HER2-negative Breast Cancer
02/25
09/25
Yang, Dongliang
NCT04201808: Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides

Recruiting
4
100
RoW
Tenofovir Alafenamide 25 MG, Vemlidy
New Discovery LLC, Beijing Ditan Hospital
Hepatitis B, Chronic
09/23
09/23
NCT04147208: Evaluate the Safety, Tolerability, and Antiviral Activity of GLS4 With Ritonavir in Patients With Chronic HBV Infection

Completed
2
250
RoW
GLS4, Morphothiadine Mesilate Capsules, RTV, Ritonavir tablet, ETV, Entecavir table
Sunshine Lake Pharma Co., Ltd.
Chronic HBV Infection
06/22
09/23
NCT05397379: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of HEC96719 in Subjects With Non-Cirrhotic Non-Alcoholic Steatohepatitis

Completed
2
68
RoW
HEC96719, Placebo
Sunshine Lake Pharma Co., Ltd.
Non-Alcoholic Steatohepatitis
09/23
09/23
NCT03108794: A Nation-wide Hospital-based Hepatitis B Registry:China Registry of Hepatitis B

Recruiting
N/A
200000
RoW
Beijing Friendship Hospital, Beijing YouAn Hospital, The First Hospital of Jilin University, Henan Provincial People's Hospital, Beijing Ditan Hospital, First Affiliated Hospital of Xinjiang Medical University, LanZhou University, The Second Affiliated Hospital of Chongqing Medical University, West China Hospital, Taiyuan No.3 Hospital, Hebei Medical University Third Hospital, Shengjing Hospital, Tianjin Third Central Hospital, Peking University First Hospital, Peking Union Medical College Hospital, The Affiliated Hospital Of Southwest Medical University, Shanghai Public Health Clinical Center, Ruijin Hospital, First Affiliated Hospital Xi'an Jiaotong University, Xiangya Hospital of Central South University, Beijing Tiantan Hospital, Wuhan University, The First Affiliated Hospital of Kunming Medical College, The Affiliated Hospital of Xuzhou Medical University, The Affiliated Hospital of Yanbian University, First Affiliated Hospital of Chongqing Medical University, The Fouth Hospital of Qinghai province, Weifang Medical University, Hunan Provincial People's Hospital, The Second Hospital of Hebei Medical University, Xixi Hospital of Hangzhou, General Hospital of Ningxia Medical University, Union Hospital,Tong Ji Medical College,Huazhong University of Science and Technology, Xinjiang Uygur Autonomous Region Traditional Chinese Medicine Hospital, Peking University People's Hospital, Nanfang Hospital of Southern Medical University, The Affiliated Hospital Of Guizhou Medical University, Guizhou Provincial People's Hospital, Hainan General Hospital, The Second Hospital of Shandong University, The First Affiliated Hospital of Shanxi Medical University, Fifth Hospital of Shijiazhuang City, Yan'an University Affiliated Hospital, Infectious Disease Hospital of Wuhai, Logistics University of Chinese People's Armed Police Forces, People's Hospital of Changji Hui Autonomous Prefecture,Xinjiang
Chronic Hepatitis B
12/22
12/25
Zheng, Xin
NCT04201808: Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides

Recruiting
4
100
RoW
Tenofovir Alafenamide 25 MG, Vemlidy
New Discovery LLC, Beijing Ditan Hospital
Hepatitis B, Chronic
09/23
09/23
NCT06055452: Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension

Recruiting
4
120
RoW
Empagliflozin 10 MG, Jardiance®, Placebo
China National Center for Cardiovascular Diseases
Pre-Heart Failure, Hypertension
10/24
12/24
NCT03469479: Neoadjuvant HAIC for Resectable Hepatocellular Carcinoma Beyond Milan Criteria

Recruiting
3
252
RoW
FOLFOX, Hepatic Arterial Infusion Chemotherapy of FOLFOX, Hepatic resection
Sun Yat-sen University
Hepatocellular Carcinoma
03/23
03/23
NCT06292013: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Recruiting
3
12500
Europe, Canada, Japan, US, RoW
Lepodisiran Sodium, LY3819469, Placebo
Eli Lilly and Company
Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a)
03/29
03/29
NCT05352516 / 2022-002188-31: A Study to Evaluate the Efficacy and Safety of HLX14 vs. Denosumab Prolia® in Postmenopausal Women With Osteoporosis at High Risk of Fracture

Completed
3
514
RoW
HLX14, Prolia®
Shanghai Henlius Biotech, Shanghai Henlius Biotech, Inc.
Postmenopausal
12/23
07/24
B-Well 2, NCT05630820 / 2022-002268-53: Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B

Active, not recruiting
3
871
Europe, Canada, Japan, US, RoW
Bepirovirsen, Placebo
GlaxoSmithKline, GlaxoSmithKline Research & Development Limited
Chronic Hepatitis B, Hepatitis B, Chronic
11/25
05/26
NCT04765995: Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of of HZBio1 in Healthy Subjects

Not yet recruiting
1
40
RoW
HZBio1 0.96mg / kg, HZBio1 3mg / kg, HZBio1 6mg / kg, HZBio1 9mg / kg, HZBio1 12mg / kg, Placebo
Hangzhou Grand Biologic Pharmaceutical, Inc., Peking Union Medical College Hospital
Healthy Participants
10/21
12/21
NCT03587103: Learning Implementation of Guideline-based Decision Support System for Hypertension Treatment: Testing Alternative Antihypertensive Regimens Using ACE-Inhibitors, Calcium Channel Blockers and Diuretics (LIGHT-ACD)

Recruiting
N/A
5000
RoW
Protocol initiate with A, Protocol initiate with C, Protocol initiate with D
China National Center for Cardiovascular Diseases
Hypertension
03/22
03/22
NCT03636334: Learning Implementation of Guideline-based Decision Support System for Hypertension Treatment (LIGHT)

Recruiting
N/A
10000
RoW
Computer-based decision support system
China National Center for Cardiovascular Diseases
Hypertension
03/22
03/22
NCT06147752: Mobile Internet Healthcare and Three Disciplines Co-management Intervention for Overweight/Obese Prediabetic Patients

Recruiting
N/A
100
RoW
mobile internet healthcare and "co-management of three disciplines"
The First Affiliated Hospital of Xiamen University
Overweight/Obesity, Prediabetes, Weight Management
03/25
03/25
FUTURE, NCT05459519: Effects of Dengzhanxixin Capsule on Platelet Function in Individuals at High Risk for Cardiovascular Disease

Recruiting
N/A
165
RoW
Dengzhanxixin Capsule plus Placebo Capsule, Placebo
China National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medial Sciences, Shenzhen, Shenzhen
Diabetes, Hypertension, Hypercholesterolemia
12/23
12/23
NCT05140837: Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy (CHESS-NCRCID 2106)

Recruiting
N/A
10000
RoW
Psychometric hepatic encephalopathy score & Stroop test, Drug therapy
Hepatopancreatobiliary Surgery Institute of Gansu Province, The First Affiliated Hospital of Anhui Medical University, Beijing Ditan Hospital, Chongqing Public Health Medical Treatment Center, Meng Chao Hepatobiliary Hospital of Fujian Medical University, Guangxi Zhuang Autonomous Region People's Hospital, Shenzhen Third People's Hospital, Guizhou people's Hospital, Wuhan Union Hospital, China, Xiangya Hospital of Central South University, The Second Affiliated Hospital of Hainan Medical University, The Third Affiliated Hospital of Hebei Medical University, The Second Affiliated Hospital of Harbin Medical University, Henan Provincial People's Hospital, Ganzhou Fifth People's Hospital, The First Hospital of Jilin University, Jiangsu People's Hospital, First Hospital of China Medical University, The Second Affiliated Hospital of Baotou Medical College, Ningxia Medical University General Hospital, The Fourth People's Hospital of Qinghai Province, Xi'an High-tech Hospital, The 10th People's Hospital affiliated to Tongji University, Qilu Hospital of Shandong University, The Third People's Hospital of Taiyuan, Xichang People's Hospital, Tianjin Third Central Hospital, The Third People's Hospital of Tibet Autonomous Region, Xinjiang Autonomous Region People's Hospital, Second People's Hospital of Yunnan Province, Hangzhou Xixi hospital, LanZhou University
Hepatic Encephalopathy, Cirrhosis
12/24
12/24
NCT05937178: Real-world Study Optimizing Nucleotide-analogues

Recruiting
N/A
20000
RoW
ETV/TAF/TDF/TMF/IFN, ETV/TAF/TDF/TMF
Huashan Hospital, The First Affiliated Hospital of Anhui Medical University, Anhui Provincial Hospital, Beijing YouAn Hospital, Peking University People's Hospital, Peking University First Hospital, Xiamen Hospital of Traditional Chinese Medicine, First Affiliated Hospital of Fujian Medical University, LanZhou University, Third Affiliated Hospital, Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Hainan General Hospital, Hebei Medical University Third Hospital, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Henan Provincial People's Hospital, The Second Affiliated Hospital of Harbin Medical University, Tongji Hospital, Wuhan Union Hospital, China, Renmin Hospital of Wuhan University, Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, the Second Hospital of Nangjing, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, The First Affiliated Hospital with Nanjing Medical University, The Affiliated Hospital of Xuzhou Medical University, The First Affiliated Hospital of Nanchang University, Shengjing Hospital, Qingdao Sixth People's Hospital, Shandong Provincial Hospital Affiliated to Shandong First Medical University, The Second Hospital of Shandong University, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, West China Hospital, Tianjin Second People's Hospital, First Affiliated Hospital of Xinjiang Medical University, The First People's Hospital of Yunnan, Shulan (Hangzhou) Hospital, Zhejiang University, Southwest Hospital, China, The Second Affiliated Hospital of Chongqing Medical University, Sichuan Provincial People's Hospital
Hepatitis B, Chronic
01/29
01/29

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