| Li, Tao |
| Active, not recruiting | 3 | 90 | Europe, Canada, US, RoW | Pimicotinib(ABSK021), Placebo | Abbisko Therapeutics Co, Ltd | Tenosynovial Giant Cell Tumor, Pigmented Villonodular Synovitis, Giant Cell Tumor of Tendon Sheath | 05/26 | 06/28 | | |
NCT04602013: Sintilimab Injection Combined With Concurrent CCRT in Locally Advanced Esophageal Squamous Cell Carcinoma |
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| Recruiting | 2 | 53 | RoW | Sintilimab, Sintilizumab, Chemotherapy, albumin-bound paclitaxel, Radiation Therapy | Sichuan Cancer Hospital and Research Institute, General Hospital of Ningxia Medical University, First Affiliated Hospital Xi'an Jiaotong University, Affiliated Hospital of Southwest Medical University, Chongqing Three Gorges Central Hospital | Locally Advanced Esophageal Squamous Cell Carcinoma | 05/22 | 05/22 | | |
IMCORT-2, NCT05472467: Camrelizumab Combination With SBRT and Concurrent Chemotherapy Treated Stage IV Oligometastatic Non-small Cell Lung Cancer |
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| Recruiting | 2 | 35 | RoW | Camrelizumab, stereotactic body radiation therapy, SBRT, Chemotherapy | Sichuan Cancer Hospital and Research Institute | Non-small Cell Lung Cancer Metastatic | 12/23 | 12/23 | | |
NCT06454578: Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection |
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| Recruiting | 2 | 30 | RoW | Adebrelimab + Apatinib | Qilu Hospital of Shandong University | Carcinoma, Hepatocellular | 12/26 | 06/27 | | |
| Recruiting | 1/2 | 310 | RoW | ICP-723 | Beijing InnoCare Pharma Tech Co., Ltd. | Solid Tumors | 06/25 | 02/28 | | |
NCT06571396: Perioperative Risk of Immunotherapy Based Neoadjuvant and Conversion Therapy for Hepatocellular Carcinoma |
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| Recruiting | N/A | 200 | RoW | | Qilu Hospital of Shandong University | Carcinoma, Hepatocellular, Immunotherapy | 08/25 | 08/26 | | |
| Recruiting | N/A | 46 | RoW | Dose-Painting Radiation | Sichuan Cancer Hospital and Research Institute | Non-small Cell Lung Cancer Stage III, Non-small Cell Lung Cancer Stage II | 12/22 | 12/25 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
NCT05937178: Real-world Study Optimizing Nucleotide-analogues |
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| Recruiting | N/A | 20000 | RoW | ETV/TAF/TDF/TMF/IFN, ETV/TAF/TDF/TMF | Huashan Hospital, The First Affiliated Hospital of Anhui Medical University, Anhui Provincial Hospital, Beijing YouAn Hospital, Peking University People's Hospital, Peking University First Hospital, Xiamen Hospital of Traditional Chinese Medicine, First Affiliated Hospital of Fujian Medical University, LanZhou University, Third Affiliated Hospital, Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Hainan General Hospital, Hebei Medical University Third Hospital, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Henan Provincial People's Hospital, The Second Affiliated Hospital of Harbin Medical University, Tongji Hospital, Wuhan Union Hospital, China, Renmin Hospital of Wuhan University, Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, the Second Hospital of Nangjing, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, The First Affiliated Hospital with Nanjing Medical University, The Affiliated Hospital of Xuzhou Medical University, The First Affiliated Hospital of Nanchang University, Shengjing Hospital, Qingdao Sixth People's Hospital, Shandong Provincial Hospital Affiliated to Shandong First Medical University, The Second Hospital of Shandong University, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, West China Hospital, Tianjin Second People's Hospital, First Affiliated Hospital of Xinjiang Medical University, The First People's Hospital of Yunnan, Shulan (Hangzhou) Hospital, Zhejiang University, Southwest Hospital, China, The Second Affiliated Hospital of Chongqing Medical University, Sichuan Provincial People's Hospital | Hepatitis B, Chronic | 01/29 | 01/29 | | |
| Wang, Lei |
NCT06346834: Sequential Vaccination of Poliomyelitis Vaccine (Vero Cells), Inactivated, Sabin Strains From Different Manufacturers |
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| Not yet recruiting | 4 | 200 | NA | sIPV | Sinovac Biotech Co., Ltd | Poliomyelitis | 08/24 | 12/24 | | |
NCT04624854: Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD) |
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| Active, not recruiting | 4 | 8250 | RoW | Clopidogrel and Aspirin dual-antiplatelet therapy, Aspirin monotherapy | Harbin Medical University, Chinese Society of Cardiology, Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Heart Diseases, Syndrome Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Coronary Disease, Vascular Diseases | 04/25 | 04/25 | | |
NCT06049927: A Phase III Clinical Trial of Quadrivalent Influenza Vaccine in Healthy Subjects Aged 6 to 35 Months |
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| Completed | 3 | 3300 | RoW | Quadrivalent influenza vaccine(0.25ml), Quadrivalent influenza vaccine(0.5ml), Trivalent influenza vaccine(BV), Trivalent influenza vaccine(BY) | Sinovac Biotech Co., Ltd | Seasonal Influenza | 05/24 | 05/24 | | |
| Recruiting | 3 | 1063 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis | 07/26 | 12/27 | | |
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NCT03397901: Transverse Colostomy for Refractory Hemorrhagic Chronic Radiation Proctitis: a Prospective Cohort Study |
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| Recruiting | N/A | 50 | RoW | Transverse colostomy | Sixth Affiliated Hospital, Sun Yat-sen University | Chronic Radiation Proctitis, Rectal Bleeding, Colostomy Stoma, Anemia | 12/20 | 12/22 | | |
| Not yet recruiting | N/A | 402 | NA | S-ketamine, esketamine, normal saline, physiological saline | Beijing Obstetrics and Gynecology Hospital, China Health Promotion Foundation, Beijing Haidian Maternal and Child Health Hospital, Obstetrics & Gynecology Hospital of Fudan University, Fourth Hospital of Shijiazhuang City, Changzhi Maternal and Child Health Hospital, Linfen Maternity&Child Healthcare Hospital, Maternal and Child Health Hospital, Jiading District, Tongzhou Maternal and Child Healthcare Hospital of Beijing, Beijing Chaoyang District Maternal and Child Health Care Hospital | Anesthesia, Analgesia, Depression, Cesarean Section, Parturition | 12/21 | 07/22 | | |
| Recruiting | N/A | 10000 | RoW | | Shanghai Jiao Tong University School of Medicine, The First Affiliated Hospital of Anhui Medical University, Anhui Provincial Hospital, First Affiliated Hospital Bengbu Medical College, LanZhou University, Henan Cancer Hospital, The First Affiliated Hospital of Zhengzhou University, The Second Affiliated Hospital of Harbin Medical University, First Affiliated Hospital of Harbin Medical University, Harbin Medical University, The First Hospital of Jilin University, Second Hospital of Jilin University, China-Japan Union Hospital, Jilin University, The First People's Hospital of Changzhou, Changzhou No.2 People's Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China, The First People's Hospital of Taicang, Wuxi Second People's Hospital, Xuzhou Central Hospital, Second Affiliated Hospital of Suzhou University, Affiliated Hospital of Nantong University, The First People's Hospital of Nantong, The Affiliated Hospital of Xuzhou Medical University, Second Affiliated Hospital of Nanchang University, The First Affiliated Hospital of Nanchang University, Jiangxi Provincial People's Hopital, Shengjing Hospital, Baotou Central Hospital, Qinghai People's Hospital, Changzhi Medical College, The First Affiliated Hospital of Shanxi Medical University, Shanxi Provincial Cancer Hospital, First Affiliated Hospital Xi'an Jiaotong University, Eastern Hepatobiliary Surgery Hospital, Shanghai Fengxian District Central Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Zhongshan Hospital, Shanghai Pudong Hospital, Central Hospital of Minhang District, Shanghai, Putuo District People's Hospital of Shanghai, Xinhua (Chongming) Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Tianjin Medical University Cancer Hospital, First Affiliated Hospital of Xinjiang Medical University, The First Affiliated Hospital of Kunming Medical College, Yinzhou Hospital Affiliated to Medical School of Ningbo University, Shaoxing Second Hospital, Shaoxing People's Hospital, First Affiliated Hospital of Wenzhou Medical University, Sir Run Run Shaw Hospital, Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Cancer Hospital, Huizhou Municipal Central Hospital, Ningbo No. 1 Hospital, People's Hospital of Hunan Province, Hainan People's Hospital, Taizhou Municipal Hospital, Xinghua City People's Hospital, Tongliao City Hospital, Jiangxi Provincial Cancer Hospital, Shandong Provincial Hospital, Qilu Hospital of Shandong University, The Affiliated Hospital of Qingdao University, Xijing Hospital | Gallbladder Neoplasms | 12/22 | 12/25 | | |
NCT03108794: A Nation-wide Hospital-based Hepatitis B Registry:China Registry of Hepatitis B |
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| Recruiting | N/A | 200000 | RoW | | Beijing Friendship Hospital, Beijing YouAn Hospital, The First Hospital of Jilin University, Henan Provincial People's Hospital, Beijing Ditan Hospital, First Affiliated Hospital of Xinjiang Medical University, LanZhou University, The Second Affiliated Hospital of Chongqing Medical University, West China Hospital, Taiyuan No.3 Hospital, Hebei Medical University Third Hospital, Shengjing Hospital, Tianjin Third Central Hospital, Peking University First Hospital, Peking Union Medical College Hospital, The Affiliated Hospital Of Southwest Medical University, Shanghai Public Health Clinical Center, Ruijin Hospital, First Affiliated Hospital Xi'an Jiaotong University, Xiangya Hospital of Central South University, Beijing Tiantan Hospital, Wuhan University, The First Affiliated Hospital of Kunming Medical College, The Affiliated Hospital of Xuzhou Medical University, The Affiliated Hospital of Yanbian University, First Affiliated Hospital of Chongqing Medical University, The Fouth Hospital of Qinghai province, Weifang Medical University, Hunan Provincial People's Hospital, The Second Hospital of Hebei Medical University, Xixi Hospital of Hangzhou, General Hospital of Ningxia Medical University, Union Hospital,Tong Ji Medical College,Huazhong University of Science and Technology, Xinjiang Uygur Autonomous Region Traditional Chinese Medicine Hospital, Peking University People's Hospital, Nanfang Hospital of Southern Medical University, The Affiliated Hospital Of Guizhou Medical University, Guizhou Provincial People's Hospital, Hainan General Hospital, The Second Hospital of Shandong University, The First Affiliated Hospital of Shanxi Medical University, Fifth Hospital of Shijiazhuang City, Yan'an University Affiliated Hospital, Infectious Disease Hospital of Wuhai, Logistics University of Chinese People's Armed Police Forces, People's Hospital of Changji Hui Autonomous Prefecture，Xinjiang | Chronic Hepatitis B | 12/22 | 12/25 | | |
NCT06377761: Study on Heart Failure with Preserved Ejection Fraction with Qishen Granules |
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| Recruiting | N/A | 80 | RoW | Qishen Granules, Placebo | Guangdong Provincial Hospital of Traditional Chinese Medicine | Heart Failure with Preserved Ejection Fraction | 12/25 | 06/26 | | |
NCT04541758: Comparing the Efficacy of Conservative Treatment With Minimally Invasive Surgery in the Treatment of Rib Fractures |
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| Not yet recruiting | N/A | 238 | NA | surgical treatment, Conservative treatment | Shanghai 6th People's Hospital | Chest Trauma, Rib Fractures, Surgery--Complications | 06/23 | 06/24 | | |
| Recruiting | N/A | 620 | RoW | Lobectomy-First, Lymphadenectomy-First | Sun Yat-sen University, Tianjin Medical University Cancer Institute and Hospital, RenJi Hospital, Sixth Affiliated Hospital, Sun Yat-sen University, First Affiliated Hospital of Jinan University, The First Affiliated Hospital with Nanjing Medical University, Hebei Medical University Fourth Hospital, Shanghai Changzheng Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Suining Central Hospital, Ningbo Medical Center Lihuili Hospital, Shanxi Provincial Cancer Hospital, The Affiliated Hospital of Xuzhou Medical University, The General Hospital of Eastern Theater Command, First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial People's Hospital, Fujian Medical University Union Hospital, First Affiliated Hospital of Kunming Medical University, Fujian Provincial Hospital, Tianjin Chest Hospital, Sichuan Cancer Hospital and Research Institute, Shenzhen People's Hospital, Tang-Du Hospital, Shandong Provincial Hospital, Gansu Provincial Hospital, Wuhan Union Hospital, China, Wuhan TongJi Hospital, The Affiliated Hospital of Qingdao University, West China Hospital, The First Affiliated Hospital of Nanchang University, Jiangsu Cancer Institute & Hospital, Dongguan People's Hospital, First People's Hospital of Foshan | Non Small Cell Lung Cancer | 12/24 | 12/29 | | |
NCT06166121: Study on Hyperlipidemia Combined With Carotid Atherosclerosis With ShenJu Granules |
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| Recruiting | N/A | 80 | RoW | ShenJu, Placebo | Guangdong Provincial Hospital of Traditional Chinese Medicine | Hyperlipidemia, Carotid Atherosclerosis | 10/23 | 12/23 | | |
NCT06196918: Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients |
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| Recruiting | N/A | 320 | RoW | Rivaroxaban 10 MG, Jiangsu Zhongbang pharmaceutical CO., LTD; Serial numbers: H20203733, Placebo, Jiangsu Zhongbang pharmaceutical CO., LTD | Nanfang Hospital, Southern Medical University | Glioma, Malignant | 08/24 | 02/25 | | |
NACSOC, NCT02972541: Neoadjuvant Chemotherapy Verse Surgery Alone After Stent Placement for Obstructive Colonic Cancer |
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| Recruiting | N/A | 248 | RoW | Stenting with neoadjuvant chemotherapy, Stenting with immediate Surgery | Beijing Chao Yang Hospital | Colorectal Cancer, Neoadjuvant Chemotherapy, Stent, Obstruction | 12/23 | 12/23 | | |
PERN, NCT02649647: Proximally Extended Resection for Rectal Cancer After Neoadjuvant Chemoradiotherapy |
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| Recruiting | N/A | 240 | RoW | Conventional resection, Proximally extended resection | Sixth Affiliated Hospital, Sun Yat-sen University, Shanghai Changzheng Hospital, Peking Union Medical College Hospital | Rectal Cancer | 12/24 | 12/28 | | |
NCT06536725: Observation of Clinical Consistency of Organoid-chips Drug Sensitivity in Chemotherapy for PCa With Visceral Metastasis |
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| Recruiting | N/A | 35 | RoW | Building Organoid-on-chips models | Tianjin Medical University Second Hospital | Prostate Cancer, Organoid | 11/25 | 12/25 | | |
NCT05418920: Clinical Trial of Reconstruction After Proximal Gastrectomy |
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| Not yet recruiting | N/A | 250 | NA | left-opening single-flap technique, double-flap group technique | Oncogastroenterology Committee of Chinese, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, General Hospital of Ningxia Medical University, Henan Provincial People's Hospital, The First Affiliated Hospital of Shanxi Medical University | Esophagitis, Reflux | 07/24 | 07/27 | | |
NCT05356520: Comparison of Different Operations for Siewert Type II Adenocarcinoma of Esophagogastric Junction |
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| Recruiting | N/A | 212 | RoW | Endoscopy Ivor-lewis, Laparoscopic transabdominal enlarged gastrectomy | Xijing Hospital of Digestive Diseases, Tang-Du Hospital, Henan Provincial People's Hospital, General Hospital of Ningxia Medical University, First Affiliated Hospital Xi'an Jiaotong University, The First Affiliated Hospital of Shanxi Medical University | Siewert Type II Adenocarcinoma of Esophagogastric Junction | 05/25 | 05/28 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
NCT06031636: Oncolytic Adenovirus(H101) Combined With PD-1 Inhibitors in Patients With Advanced Malignant Pleural Mesothelioma |
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| Recruiting | N/A | 15 | RoW | Oncolytic Adenovirus H101, Recombinant Human Type-5 Adenovirus, Programmed death receptor-1 inhibitor | Tianjin Medical University Second Hospital | Malignant Pleural Mesothelioma, Advanced | 07/26 | 07/26 | | |
NCT05002426: Rouviere Sulcus Plane and Hepatic Hilum Plane, Which is Better as a Landmark in Laparoscopic Bile Duct Surgerys |
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| Recruiting | N/A | 100 | RoW | | The Second Hospital of Anhui Medical University | Cholelithiasis, Laparoscopic Cholecystectomy | 10/21 | 10/21 | | |
NCT05126160: Immune Score Based Radiomics in Nasopharyngeal Carcinoma |
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| Recruiting | N/A | 494 | RoW | Immune Score Based Radiomics | Zhejiang Cancer Hospital, Renmin Hospital of Wuhan University, First Affiliated Hospital of Wenzhou Medical University, Ningbo Medical Center Lihuili Hospital, Ningbo No. 1 Hospital | Nasopharyngeal Carcinoma | 10/22 | 12/27 | | |
| Recruiting | N/A | 300 | RoW | CCTA and 18F-FDG-PET/CT | Shanghai Zhongshan Hospital | Coronary Artery Disease | 10/22 | 12/22 | | |
| Liu, Gang |
SPH3127-301, NCT05359068: Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension |
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| Completed | 3 | 957 | RoW | SPH3127 tablet, Valsartan | Shanghai Pharmaceuticals Holding Co., Ltd | Essential Hypertension | 12/23 | 12/23 | | |
NCT05525637: Safety and Efficacy Study of YZJ-1139 in Insomnia Disorder |
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| Recruiting | 3 | 1041 | RoW | YZJ-1139 20mg, YZJ-1139 40mg, Placebo | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. | Insomnia Disorder | 12/24 | 12/24 | | |
NCT05741099: Application and Research of Mesenchymal Stem Cells in Alleviating Severe Development of COVID-19 Infection |
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| Recruiting | 1/2 | 20 | RoW | Umbilical cord mesenchymal stem cells implantation, Comparator | Hebei Medical University | COVID-19 | 01/24 | 01/25 | | |
NCT06672276: To Evaluate the Pharmacokinetics and Safety of TQD3606 for Injection in Subjects With Renal Insufficiency |
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| Not yet recruiting | 1 | 32 | RoW | TQD3606 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Resistant to Gram-positive, Gram-negative and Anaerobic Bacteria | 05/25 | 11/25 | | |
NCT04953117: A Safety and Efficacy Study of Lepu® Drug Coated Balloon in Treatment of Coronary Small-vessel Disease |
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| Recruiting | N/A | 286 | RoW | DCB of Lepu Medical(dimeter≥2.00 mm), Coronary Drug Coated Balloon Catheter of Lepu Medical for coronary small vessels, Restore DEB, RESTORE Paclitaxel releasing coronary balloon catheter, DCB of Lepu Medical(dimeter<2.00 mm), Coronary Drug Coated Balloon Catheter of Lepu Medical for coronary very small vessels | Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Artery Disease | 06/22 | 04/23 | | |
NCT06351566: Effects of Vitamin D3 and Prebiotics Supplementation on Cardiovascular Risk Factors in Patients With Type 2 Diabetes |
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| Recruiting | N/A | 200 | RoW | Vitamin D3, Cholecalciferol, Prebiotics, Inulin, Vitamin D3 placebo, Prebiotics placebo | Huazhong University of Science and Technology | Diabetes Mellitus, Type 2 | 12/24 | 12/25 | | |
NCT06553729: Effects of Vitamin D and Prebiotic Supplementation on Glucose Control During Pregnancy |
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| Not yet recruiting | N/A | 500 | RoW | Vitamin D3, Cholecalciferol, Prebiotics, Inulin, Prebiotics placebo, Vitamin D3 placebo | Huazhong University of Science and Technology | Glucose Intolerance During Pregnancy | 12/26 | 12/26 | | |
| Liu, Ying Su |
NCT04468529: Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure |
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| Completed | 3 | 154 | RoW | Recombinant human Neuregulin for injection, Neucardin, Placebo | Zensun Sci. & Tech. Co., Ltd. | Chronic Systolic Heart Failure | 04/22 | 04/24 | | |
NCT05745259: Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ） |
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| Recruiting | 3 | 1630 | RoW | Alteplase, rt-PA, Tenecteplase, TNK-tPA | Beijing Tiantan Hospital, Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd, The Place Pharmaceutical(Jiangsu) Co., Ltd | Acute Ischemic Stroke | 11/23 | 03/24 | | |
| Recruiting | 3 | 918 | Europe, Canada, Japan, RoW | Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil | Jazz Pharmaceuticals, BeiGene, Ltd. | Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma | 05/25 | 05/26 | | |
PANOVA-3, NCT03377491: Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel |
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| Completed | 3 | 571 | Europe, Canada, US, RoW | NovoTTF-200T, TTFields, Gemcitabine, nab paclitaxel | NovoCure Ltd. | Pancreas Adenocarcinoma | 10/24 | 10/24 | | |
JSKN003-302, NCT06079983: JSKN003 Versus Treatment Of Physician'S Choice For HER2-low, Unresectable and/or Metastatic Breast Cancer Subjects |
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| Not yet recruiting | 3 | 400 | RoW | JSKN003, Capecitabine tablets, Gemcitabine hydrochloride for injection, Vinorelbine tartrate injection, Paclitaxel for injection (albumin-bound type), Docetaxel injection, Eribulin mesylate injection | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Breast Cancer | 04/25 | 03/29 | | |
STRIDES, NCT05490563: - a Clinical Research Study of an Investigational New Drug to Treat Spinocerebellar Ataxia |
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| Terminated | 2/3 | 23 | Europe, US, RoW | SLS-005, Placebo | Seelos Therapeutics, Inc. | Spinocerebellar Ataxia Type 3 | 11/23 | 11/23 | | |
HNGC-004, NCT03939962: Camrelizumab Combined With FOLFOX Neoadjuvant Therapy for Resectable Gastric and Gastroesophageal Junctional Adenocarcinoma |
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| Active, not recruiting | 2 | 60 | RoW | SHR1210 combined with FOLFOX | Henan Cancer Hospital | Gastric Cancer | 05/21 | 05/24 | | |
| Recruiting | 2 | 20 | RoW | camrelizumab, SHR-1210, Apatinib Mesylate | Henan Cancer Hospital | Advanced Gastric Carcinoma | 06/22 | 08/23 | | |
MRG002-002, NCT04837508: A Study of MRG002 in the Treatment of HER2-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer |
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| Recruiting | 2 | 86 | RoW | MRG002 | Shanghai Miracogen Inc. | Advanced or Metastatic Biliary Tract Cancer | 12/22 | 08/23 | | |
NCT05188209: A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Advanced Gastric Cancer. |
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| Recruiting | 2 | 60 | RoW | MRG003 | Shanghai Miracogen Inc. | Advanced or Metastatic Gastric Cancer, Advanced or Metastatic Gastroesophageal Junction Carcinoma | 03/23 | 08/23 | | |
| Not yet recruiting | 2 | 22 | RoW | Cadonilimab (®), a PD-1/CTLA-4 bi-specific antibody, Neoadjuvant therapy with Cadonilimab | LiuYing | Colorectal Cancer, Mismatch Repair-deficient (dMMR), Microsatellite Instability-high (MSI-H), Neoadjuvant Therapy | 12/23 | 12/23 | | |
NCT05247216: A Phase 2 Study of Hemay007 in Patients With Rheumatoid Arthritis |
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| Completed | 2 | 140 | RoW | Hemay007 800 mg QD group, Hemay007 1200 mg QD group, Hemay007 600 mg QD group, Hemay007 placebo group | Tianjin Hemay Pharmaceutical Co., Ltd | Rheumatoid Arthritis | 06/23 | 06/23 | | |
NCT06173037: RC88 in Platinum-Resistant Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer |
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| Recruiting | 2 | 88 | RoW | RC88, RC88 for Injection | RemeGen Co., Ltd. | Primary Peritoneal Cancer, Fallopian Tube Cancer, Epithelial Ovarian Cancer | 06/26 | 12/26 | | |
NCT06231680: Thalidomide Prevention or Treatment of Camrelizumab-induced Reactive Cutaneous Capillary Endothelial Proliferation (RCCEP) |
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| Recruiting | 2 | 132 | RoW | Camrelizumab, SHR-1210, Thalidomide 50mg, Thalidomide, Thalidomide 100mg, Thalidomide 200mg, Chemotherapy, Platinum-based chemotherapy | Henan Cancer Hospital, First Affiliated Hospital Xi'an Jiaotong University | Lung Cancer, Nonsmall Cell, Esophageal Carcinoma | 06/24 | 09/25 | | |
NCT06227325: Disitamab Vedotin Combined With Sintilimab and XELOX Perioperative Treatment for Resectable Gastric Caner With HER2 Overexpression |
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| Not yet recruiting | 2 | 27 | RoW | RC48 combined with Sintilimab and XELOX, Disitamab vedotin combined with Sintilimab and XELOX | Henan Cancer Hospital | Gastric Cancer | 12/24 | 12/25 | | |
NCT06293014: TAS-102 Combined With Bevacizumab for Second-line Maintenance Treatment of Advanced Colorectal Cancer |
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| Recruiting | 2 | 224 | RoW | TAS-102+bevacizumab, Trifluridine and Tipiracil Hydrochloride Tablets; bevacizumab, Standard chemotherapy+bevacizumab, Bevacizumab | Henan Cancer Hospital | Colorectal Cancer | 10/25 | 11/26 | | |
NCT06749730: Adebrelimab Combined with Apatinib and Gemcitabine and Cisplatin (GP) First-line Treatment for Unresectable Biliary Tract Carcinoma |
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| Recruiting | 2 | 63 | RoW | Adebrelimab, Apatinib, gemcitabine and cisplatin | Henan Cancer Hospital | Unresectable Biliary Tract Carcinoma | 12/26 | 06/27 | | |
NCT04774419: Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery |
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| Recruiting | 2 | 62 | US | Intensity modulated radiation therapy (IMRT), Dostarlimab, TSR-042, Hypofractionated IMRT | Memorial Sloan Kettering Cancer Center, Tesaro, Inc. | Endometrial Cancer | 02/26 | 02/26 | | |
ACTIVATE, NCT05819359: Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD |
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| Active, not recruiting | 2 | 237 | Europe, Canada, US | BIA 28-6156 10 mg, BIA 28-6156 60 mg, Placebo | Bial R&D Investments, S.A. | Parkinson's Disease | 03/26 | 07/26 | | |
NCT06166836: a Study to Evaluate the Safety and Efficacy of D-1553 Combined With IN10018 in KRAS G12C Mutant Solid Tumors |
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| Recruiting | 1/2 | 140 | RoW | D1553, IN10018（Ifebemtinib）, BI 853520 | InxMed (Shanghai) Co., Ltd., InventisBio Co., Ltd | Solid Tumor | 12/25 | 12/26 | | |
NCT04755543: A Study of LP002 for the Treatment of Patients With Malignant Digestive System Neoplasms |
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| Recruiting | 1 | 94 | RoW | LP002, Cisplatin, Fluorouracil, OH2 oncolytic virus | Taizhou HoudeAoke Biomedical Co., Ltd. | Digestive System Neoplasms | 06/21 | 06/22 | | |
| Enrolling by invitation | N/A | 200 | RoW | the paste group, the meridian group | The Affiliated Hospital of Qingdao University | Massage, Meridian, Pain | 05/21 | 05/21 | | |
| Recruiting | N/A | 10000 | RoW | Coronary angiography, CT angiography of aorta, CTA, CT angiography of pulmonary arteries., Electrocardiogram, ECG, Cardiac Troponin, Biomarkers of myocardial injury | West China Hospital | Chest Pain, Acute Aortic Dissection, Pulmonary Embolism, Acute Myocardial Infarction Type 1, Acute Coronary Syndrome | 10/21 | 10/22 | | |
NCT06087380: Auricular Acupressure on Improving Pain and Heart Variability in Patients After Cervical Spine Surgery |
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| Completed | N/A | 62 | RoW | auricular acupressure, standard ward care | National Taipei University of Nursing and Health Sciences, Taipei Veterans General Hospital, Taiwan | Auricular Acupressure, Cervical Spine Surgery | 03/23 | 03/23 | | |
NCT05528484: Self-reported Outcomes of Patients in ERAS Nursing |
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| Recruiting | N/A | 600 | RoW | ERAS nursing, non eras nursing | The Second Hospital of Shandong University | Enhanced Recovery After Surgery | 06/23 | 08/27 | | |
NCT05455099: A Multicenter Study of Ultrafast Pulse Wave Velocity in Obese Chinese Han Adults |
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| Recruiting | N/A | 2400 | RoW | Carotid ultrasound examination 1, Carotid ultrasound examination 2 | First Hospital of China Medical University | Carotid Artery Diseases | 08/23 | 07/24 | | |
| Active, not recruiting | N/A | 82 | US | | Koneksa Health, Merck Sharp & Dohme LLC, Regeneron Pharmaceuticals | Parkinson Disease | 02/26 | 02/26 | | |
MET-LVH, NCT05719337: Multi-Modality Echocardiographic Techniques in Pathological Left Ventricular Hypertrophy Adults |
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| Recruiting | N/A | 660 | RoW | Echocardiography | First Hospital of China Medical University, Wuhan Union Hospital, China | Left Ventricular Hypertrophy | 08/24 | 08/25 | | |
| Shang, Wei |
NCT05998902: Optimizing Early Nutrition Support in Severe Stroke-2 |
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| Recruiting | 3 | 546 | RoW | Trophic enteral feeding combined with supplemental parenteral nutrition, Full enteral feeding | Wen Jiang-3, Tang-Du Hospital, Xi'an Central Hospital, Xi'an Gaoxin Hospital, First Affiliated Hospital of Xi'an Medical University, Xi'an No.3 Hospital, First People's Hospital of Xianyang, Nanfang Hospital, Southern Medical University, Tongji Hospital, Qilu Hospital of Shandong University, The Second Hospital of Shandong University, PLA 960 Hospital, Daping Hospital, The Third Military Medical University (Army Medical University), The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, First Hospital Affiliated to Zhengzhou University, Gansu Provincial Central Hospital, The First Hospital of Changsha City, Shaanxi Provincial People's Hospital, Yulin No.2 Hospital, Yulin No.1 Hospital, Xijing Hospital | Severe Stroke, Acute Stroke, Dysphagia | 07/26 | 10/26 | | |
NCT06009861: Neoadjuvant Tislelizumab Plus Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer (NeoSPOT) |
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| Recruiting | 2 | 110 | RoW | Tislelizumab, Albumin-Bound Paclitaxel, Cisplatin | Peking University Hospital of Stomatology | Oral Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma | 06/24 | 08/27 | | |
| Zhao, Xiaogang |
| Recruiting | N/A | 300 | RoW | uniport video-assisted thoracoscopic surgery, two ports video-assisted thoracoscopic surgery, three ports video-assisted thoracoscopic surgery | The Second Hospital of Shandong University | Single-port Video-assisted Thoracoscopic Surgery | 12/22 | 12/25 | | |
NCT05511441: Routine Minimally Invasive Thoracic Surgery Without Aspirin Withdraw |
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| Recruiting | N/A | 60 | RoW | Surgery Without Aspirin Withdraw | The Second Hospital of Shandong University | Aspirin Sensitivity, Surgery | 06/23 | 06/25 | | |
NCT04451473: Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery |
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| Recruiting | N/A | 350 | RoW | Enhanced Recovery After Surgery (ERAS ), Traditional perioperative management without Enhanced Recovery After Surgery (ERAS ) | The Second Hospital of Shandong University | Lung Cancer, Surgery, ERAS | 06/23 | 06/27 | | |
NCT05479825: Tubeless Intersegmentectomy Plane Identification With Fluorography |
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| Recruiting | N/A | 60 | RoW | inflation- deflation line combined with ICG fluorography | The Second Hospital of Shandong University | Operation Time, Postoperative Complications | 12/26 | 12/28 | | |
| Li, Yuliang |
NCT03356236: Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma Following Local Ablation |
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| Recruiting | N/A | 828 | RoW | | Yue Han | Hepatocarcinoma | 08/24 | 12/24 | | |
| Zhao, Yunpeng |
NCT05269784: Minimally Invasive Lung Surgery Under ERAS With Completely Tubeless Protocol Compared With That With Partially Tubeless Protocol |
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| Recruiting | N/A | 600 | RoW | Minimally Invasive Lung Surgery Under ERAS With Completely Tubeless Protocol, Minimally Invasive Lung Surgery Under ERAS With partially Tubeless Protocol | The Second Hospital of Shandong University | Lung Diseases, ERAS, Surgery | 12/22 | 07/25 | | |
| Recruiting | N/A | 300 | RoW | uniport video-assisted thoracoscopic surgery, two ports video-assisted thoracoscopic surgery, three ports video-assisted thoracoscopic surgery | The Second Hospital of Shandong University | Single-port Video-assisted Thoracoscopic Surgery | 12/22 | 12/25 | | |
NCT05270616: Robotic Versus Video-assisted Lobectomy/Segmentectomy for Lung Surgery |
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| Recruiting | N/A | 800 | RoW | robotic surgery, uniport surgery, multiple- port surgery | The Second Hospital of Shandong University | Lung Diseases, Surgery | 06/23 | 06/28 | | |
NCT04451473: Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery |
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| Recruiting | N/A | 350 | RoW | Enhanced Recovery After Surgery (ERAS ), Traditional perioperative management without Enhanced Recovery After Surgery (ERAS ) | The Second Hospital of Shandong University | Lung Cancer, Surgery, ERAS | 06/23 | 06/27 | | |
NCT04217239: A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy |
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| Recruiting | N/A | 200 | RoW | MIE Ivor- Lewis, MIE McKeown | The Second Hospital of Shandong University | Esophageal Cancer | 12/23 | 12/28 | | |
NCT04688801: Ajuvant Chemotherapy and Immunotherapy in Patients With Esophageal, Esophageal- Gastric Junction Cancer |
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| Recruiting | N/A | 200 | RoW | Chemotherapy Drugs, Cancer, Immunotherapy | The Second Hospital of Shandong University | Esophageal Cancer, Gastroesophageal Cancer, Immunotherapy, Adjuvant | 12/23 | 12/27 | | |
NCT05479825: Tubeless Intersegmentectomy Plane Identification With Fluorography |
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| Recruiting | N/A | 60 | RoW | inflation- deflation line combined with ICG fluorography | The Second Hospital of Shandong University | Operation Time, Postoperative Complications | 12/26 | 12/28 | | |
| Lu, Qinghua |
NCT05182463: Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients |
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| Recruiting | 4 | 5000 | RoW | Peginterferon Alfa-2B, Nucleoside Analogs | Third Affiliated Hospital, Sun Yat-Sen University | Hepatitis B, Chronic | 12/26 | 11/29 | | |
| Sun, Lin |
| Active, not recruiting | 4 | 800 | RoW | Sodium Oligomannate Capsules (GV-971) | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer Disease | 01/25 | 06/25 | | |
FLAT, NCT03805191: A Study for Sufficient Acarbose Decreased Glucose Excursion in Type 2 Diabetic Patients |
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| Recruiting | N/A | 900 | RoW | | Qilu Hospital of Shandong University, Bayer | Type 2 Diabetes Mellitus, Poor Glycemic Control | 11/20 | 12/22 | | |
NCT04968028: Multi-centre Study to Evaluate ACAF Versus Laminoplasty in Treating Cervical Ossification of the Posterior Longitudinal Ligament |
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| Recruiting | N/A | 164 | RoW | ACAF, Anterior Controllable Antedisplacement and Fusion, Laminoplasty | Shanghai Changzheng Hospital, Changhai Hospital, Shanghai 6th People's Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Tongji Hospital, Peking University Shenzhen Hospital, The Second Affiliated Hospital of Harbin Medical University, Xuanwu Hospital, Beijing, Jining Medical University, The Affiliated Hospital of Qingdao University, Shanxi Bethune Hospital, Tang-Du Hospital | Ossification of Posterior Longitudinal Ligament, Cervical Spondylosis With Myelopathy | 07/25 | 12/26 | | |
| Du, Lutao |
| Recruiting | N/A | 10000 | RoW | | Eastern Hepatobiliary Surgery Hospital | Carcinoma, Hepatocellular | 07/22 | 07/23 | | |
| Su, Haichuan |
NCT06467786: Study on the Therapeutic Effect of Irinotecan Liposomes in Small Cell Lung Cancer |
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| Recruiting | 4 | 24 | RoW | Irinotecan hydrochloride liposome injection | Tang-Du Hospital | Small Cell Lung Cancer | 09/25 | 09/28 | | |
NCT05042375: A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer |
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| Recruiting | 3 | 450 | RoW | camrelizumab + famitinib, pembrolizumab, camrelizumab | Jiangsu HengRui Medicine Co., Ltd. | Non-small Cell Lung Cancer | 12/23 | 12/25 | | |
NCT06300177: D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure |
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| Recruiting | 3 | 522 | RoW | D-1553 Tablet, Docetaxel injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non Small Cell Lung Cancer | 10/26 | 12/27 | | |
| Not yet recruiting | 3 | 420 | RoW | Anlotinib hydrochloride capsule + TQB2450 injection, Chemotherapy drug | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Endometrial Cancer | 12/27 | 06/29 | | |
NCT05767892: YK-029A as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations |
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| Not yet recruiting | 3 | 350 | RoW | YK-209A tablet, Pemetrexed+carboplatin/Cisplatin | Suzhou Puhe Pharmaceutical Technology Co., LTD | Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) | 07/25 | 12/26 | | |
TQB2450-AL2846-III-01, NCT05922345: Evaluation of the Efficacy and Safety of AL2846 Capsule Combined With TQB2450 Injection Compared to Docetaxel Injection in Advanced Non-small Cell Lung Cancer Patients Who Have Failed With Immunotherapy. |
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| Recruiting | 3 | 518 | RoW | TQB2450 injection, docetaxel injection matching placebo, AL2846 capsules, TQB2450 placebo, docetaxel injection, AL2846 matching placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non-small Cell Lung Cancer | 08/25 | 12/25 | | |
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer |
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| Recruiting | 3 | 1016 | Europe, Canada, Japan, US, RoW | LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed | Eli Lilly and Company, Loxo Oncology, Inc. | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 10/26 | 10/29 | | |
NCT04291248: A Study of Anlotinib Combined With AK105 Injection in Subjects With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Advanced Solid Tumor |
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| Not yet recruiting | 2 | 138 | RoW | AK105, Anlotinib | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | MSI-H or dMMR Advanced Solid Tumors | 12/22 | 12/22 | | |
| Recruiting | 2 | 120 | RoW | TQB3616 capsules, Fulvestrant injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | HR-positive, HER2-negative Advanced Breast Cancer | 01/23 | 01/23 | | |
| Recruiting | 2 | 120 | RoW | TQB3616 capsules, Fulvestrant injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | HR-positive, HER2-negative Advanced Breast Cancer | 01/23 | 01/23 | | |
TQB3616-ALTN-II-01, NCT04924192: A Clinical Study of TQB3616 Capsules Combined With Anlotinib Hydrochloride Capsules or Standard Chemotherapy Second-line and Above in the Treatment of Advanced Lung Cancer |
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| Recruiting | 2 | 126 | RoW | TQB3616 capsules, Anlotinib Hydrochloride capsules, Irinotecan Hydrochloride for Injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Advanced Lung Carcinoma | 05/23 | 12/23 | | |
SPH5030-201, NCT06434597: A Clinical Study of SPH5030 Tablets in the Treatment of Her2-positive/Mutated Biliary Tract OR Colorectal Cancer Patients. |
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| Recruiting | 2 | 60 | RoW | SPH5030 | Shanghai Pharmaceuticals Holding Co., Ltd | Biliary Tract or Colorectal Cancer With Her2-positive/Mutated | 12/26 | 12/26 | | |
| Recruiting | 1/2 | 500 | Europe, Canada, Japan, US, RoW | Oral repotrectinib (TPX-0005), repotrectinib | Turning Point Therapeutics, Inc., Zai Lab (Shanghai) Co., Ltd. | Locally Advanced Solid Tumors, Metastatic Solid Tumors | 02/28 | 02/28 | | |
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NCT04990063: Adoptive TKC Transfer Combined With Chemotherapy for Advanced Non-small Cell Lung Cancer (NSCLC) |
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| Recruiting | 1 | 20 | RoW | Chemotherapy, Adoptive TKC transfer therapy | suhaichuan, Shanghai Biomed-union Biotechnology Co., Ltd. | Advanced Non-small Cell Lung Cancer, Chemotherapy | 08/22 | 11/23 | | |
