| Jiang, Jun |
OPTIMA-6, NCT05410925: Efficacy and Safety of a Half-dose Bolus of r-SAK Prior to Primary PCI in ST-elevation Myocardial Infarction |
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| Recruiting | 4 | 2260 | RoW | Recombinant staphylokinase, Placebo | The First Affiliated Hospital with Nanjing Medical University | ST Elevation Myocardial Infarction | 12/26 | 12/27 | | |
NCT04624854: Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD) |
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| Active, not recruiting | 4 | 8250 | RoW | Clopidogrel and Aspirin dual-antiplatelet therapy, Aspirin monotherapy | Harbin Medical University, Chinese Society of Cardiology, Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Heart Diseases, Syndrome Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Coronary Disease, Vascular Diseases | 04/25 | 04/25 | | |
MATE, NCT04937699: Sequential MonotherApy of TicagrElor and Clopidogrel After Coronary Intervention |
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| Recruiting | 4 | 2690 | RoW | Standard-DAPT of Ticagrelor plus aspirin, DAPT, Sequential monotherapy of Ticagrelor and clopidogrel, SAPT | Second Affiliated Hospital, School of Medicine, Zhejiang University | Acute Coronary Syndrome, Percutaneous Coronary Intervention | 12/26 | 12/26 | | |
CYCLONE 3, NCT05288166: A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) |
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| Active, not recruiting | 3 | 900 | Europe, Canada, Japan, US, RoW | Abemaciclib, LY2835219, Abiraterone, Prednisone or Prednisolone, Placebo for Abemaciclib | Eli Lilly and Company | Prostatic Neoplasms, Neoplasm Metastasis, Urogenital Neoplasms, Physiological Effects of Drugs, Antineoplastic Agents, Antineoplastic Agents, Hormonal, Androgens, Hormones, Hormones, Hormone Substitutes, and Hormone Antagonists, Abiraterone Acetate, Steroid Synthesis Inhibitors, Cytochrome P-450, Enzyme Inhibitors, Prednisone, Prednisolone, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6 | 02/24 | 10/27 | | |
NCT03351062: Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast Cancer |
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| Recruiting | 3 | 844 | RoW | Tamoxifen, Tamoxifen citrate, Toremifene, fareston | Chinese Anti-Cancer Association, Fudan University, Henan Cancer Hospital, The First Hospital of Jilin University, Southwest Hospital, China, First Hospital of China Medical University, Guangdong Provincial People's Hospital, Harbin Medical University, First Affiliated Hospital of Chongqing Medical University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Jiangsu Provincial People's Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Zhejiang Cancer Hospital, Tianjin Medical University Cancer Institute and Hospital, Union hospital of Fujian Medical University, Hebei Tumor Hospital, Hunan Cancer Hospital, Affiliated Hospital of Qinghai University, Wuhan TongJi Hospital, Hainan People's Hospital, The Third Affiliated Hospital of Kunming Medical College., The Third Affiliated Hospital of Nanchang University | Breast Cancer Female | 12/25 | 12/25 | | |
LOVEinSTEMI, NCT04063345: Long-term Clinical Outcomes of intraVascular Ultrasound-guided vs Angiography-guided Primary pErcutaneous Intervention in Patients With Acute ST Segment Elevated Myocardial Infarction |
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| Not yet recruiting | 2/3 | 200 | RoW | IVUS-guided PCI, Angiography-guided PCI | Second Affiliated Hospital, School of Medicine, Zhejiang University, Ningbo No. 1 Hospital, First Affiliated Hospital of Wenzhou Medical University, Second Affiliated Hospital of Wenzhou Medical University, The First Affiliated Hospital of Xiamen University, Shanghai Chest Hospital, Taizhou Hospital | ST Elevation Myocardial Infarction | 10/22 | 10/23 | | |
| Recruiting | 2 | 270 | RoW | TQB2102 for injection, TQB2102 for injection combined with Benmelstobart injection | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Non-Small Cell Lung Cancer | 10/25 | 02/26 | | |
NCT06434415: Prognostic Value of Angio-IMR in Hypertrophic Cardiomyopathy Patients |
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| Active, not recruiting | N/A | 500 | NA | | Second Affiliated Hospital, School of Medicine, Zhejiang University, Ningbo Medical Center Lihuili Hospital | Hypertrophic Cardiomyopathy | 01/24 | 07/24 | | |
NCT05978726: Ticagrelor Versus Clopidogrel for CMD in Patients With AMI: A Retrospective Study Based on the Angio-IMR |
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| Completed | N/A | 325 | RoW | Dual antiplatelet therapy with aspirin and either ticagrelor or clopidogrel | Second Affiliated Hospital, School of Medicine, Zhejiang University | Coronary Heart Disease | 05/20 | 05/22 | | |
NCT04953117: A Safety and Efficacy Study of Lepu® Drug Coated Balloon in Treatment of Coronary Small-vessel Disease |
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| Recruiting | N/A | 286 | RoW | DCB of Lepu Medical(dimeter≥2.00 mm), Coronary Drug Coated Balloon Catheter of Lepu Medical for coronary small vessels, Restore DEB, RESTORE Paclitaxel releasing coronary balloon catheter, DCB of Lepu Medical(dimeter<2.00 mm), Coronary Drug Coated Balloon Catheter of Lepu Medical for coronary very small vessels | Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Artery Disease | 06/22 | 04/23 | | |
HERO-HF, NCT05742230: Effect of Henagliflozin on Cardiac Function in Type 2 Diabetes Patients With Chronic Heart Failure |
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| Recruiting | N/A | 1932 | RoW | Henagliflozin 10 mg, blank control | Second Affiliated Hospital, School of Medicine, Zhejiang University | Heart Failure | 07/24 | 12/25 | | |
| Not yet recruiting | N/A | 500 | RoW | Assessment of plaque morphology, structure, and stability in non-culprit lesions | Chinese PLA General Hospital | Coronary Arterial Disease (CAD), Acute Coronary Syndromes | 12/27 | 12/31 | | |
DCB-PSTEMI, NCT06742125: Drug-Coated Balloon Versus Drug-Eluting Stent in Patient With Premature ST-Segment Elevation Myocardial Infarction |
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| Not yet recruiting | N/A | 1244 | NA | Drug-coated balloon (DCB), Drug-eluting stent (DES) | Second Affiliated Hospital, School of Medicine, Zhejiang University, The First Affiliated Hospital of Zhengzhou University, Peking University First Hospital, Suzhou Municipal Hospital, First Affiliated Hospital of Ningbo University | ST-elevation Myocardial Infarction (STEMI) | 01/28 | 01/28 | | |
| Not yet recruiting | N/A | 1066 | RoW | ITS plus OMT, OMT | Second Affiliated Hospital, School of Medicine, Zhejiang University | Coronary Artery Disease, Myocardial Ischaemia | 05/25 | 05/26 | | |
REVISE, NCT05923489: Routine Angiography Follow-Up After Percutaneous Coronary Intervention in High-Risk Patients |
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| Recruiting | N/A | 2618 | RoW | Routine Angiography Follow-up, Routine Clinical Follow-up | Second Affiliated Hospital, School of Medicine, Zhejiang University, Jinhua Central Hospital, Changxing People's Hospital, The Affiliated Hospital of Hangzhou Normal University, Second Affiliated Hospital of Shantou University Medical College, Dongyang People's Hospital, First Affiliated Hospital of Wenzhou Medical University, Huizhou Municipal Central Hospital, The First Affiliated Hospital of Ningbo University | Coronary Artery Disease | 10/26 | 10/29 | | |
| Huang, Jian |
NCT05131841: Cipterbin Combined With Vinorelbine in the Treatment of HER2-positive MBC |
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| Recruiting | 4 | 60 | RoW | Cipterbin Combined With Vinorelbine | Zhejiang Cancer Hospital, Proswell Medical Corporation | Metastatic Breast Cancer | 12/22 | 12/22 | | |
CLOVER, NCT03926091: Study Comparing 4 Cycles With 6 Cycles of TC (Docetaxel+Cyclophosphamide) Adjuvant Chemotherapy for 1-3 Lymph Node Positive ER+/HER2- Early Breast Cancer |
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| Recruiting | 3 | 2172 | RoW | Docetaxel, docetaxel injection, Cyclophosphamide, Cyclophosphamide injection | Fudan University | Breast Cancer | 11/24 | 11/25 | | |
NCT05600322: Comparative Study of Hexvix Blue Light Cystoscopy and White Light Cystoscopy in the Detection of Bladder Cancer |
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| Completed | 3 | 158 | RoW | Hexaminolevulinate Hydrochloride, Hexvix, Richard Wolf Photodynamic Diagnostic Equipment (PDD) system, System Blue | Photocure, Jiangsu Yahong Meditech Co., Ltd aka Asieris, Richard Wolf GmbH, Tigermed-Jyton Co., Ltd. | Bladder Cancer | 07/23 | 07/23 | | |
NCT06241755: Clinical Trial for Evaluating the Efficacy and Safety of BCG for Therapeutic Use in the Prevention of Postoperative Recurrence of Medium/High-risk Non-muscle Invasive Bladder Cancer (NMIBC) |
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| Recruiting | 3 | 412 | RoW | BCG for Therapeutic Use, BCG | Chengdu CoenBiotech Co., Ltd, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Non-Muscle Invasive Bladder Cancer | 09/25 | 09/26 | | |
NCT05433480: A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer |
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| Active, not recruiting | 3 | 274 | RoW | BPI-16350, placebo, Fulvestrant | Betta Pharmaceuticals Co., Ltd. | Breast Cancer | 12/23 | 07/25 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
JSKN003-302, NCT06079983: JSKN003 Versus Treatment Of Physician'S Choice For HER2-low, Unresectable and/or Metastatic Breast Cancer Subjects |
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| Not yet recruiting | 3 | 400 | RoW | JSKN003, Capecitabine tablets, Gemcitabine hydrochloride for injection, Vinorelbine tartrate injection, Paclitaxel for injection (albumin-bound type), Docetaxel injection, Eribulin mesylate injection | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Breast Cancer | 04/25 | 03/29 | | |
| Recruiting | 3 | 314 | RoW | Investigational drug: Recombinant Anti-HER2 Humanized Monoclonal Antibody - Monomethyl Auristatin F Conjugates for Injection (FS-1502), Control drug: Trastuzumab emtansine (Kadcyla, T-DM1) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | Breast Cancer | 07/25 | 01/26 | | |
| Active, not recruiting | 3 | 650 | Europe, Canada, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Ibrutinib | Loxo Oncology, Inc., Eli Lilly and Company | Chronic Lymphocytic Leukemia, Leukemia, Lymphocytic, Leukemia, B-cell, Small Lymphocytic Lymphoma | 02/25 | 08/28 | | |
NCT05075512: The Efficacy and Safety of Anlotinib Combined With Fulvestrant in Patients With Advanced Breast Cancer |
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| Recruiting | 2 | 40 | RoW | anlotinib, fulvestrant, AL3818 | Zhejiang Cancer Hospital | Breast Neoplasm Female | 08/23 | 08/26 | | |
NCT04799847: Catumaxomab in Patients With Non-Muscle-Invasive Bladder Cancer Who Have Failed or Are Intolerant to BCG Vaccine |
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| Recruiting | 1/2 | 161 | RoW | Catumaxomab | LintonPharm Co.,Ltd. | Bladder Cancer | 11/24 | 11/24 | | |
| Recruiting | 1/2 | 725 | RoW | JSKN003 | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Advanced Solid Tumor | 12/24 | 12/26 | | |
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NCT06001580: A Phase I Study of BR101 Injection Alone in Subjects With Advanced Solid Tumors |
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| Recruiting | 1 | 36 | RoW | BR101 | Zhe Jiang Hisun Bioray Bio-pharmaceu tical Co.Ltd | Advanced Solid Tumor | 12/23 | 06/26 | | |
NCT06672263: A Clinical Trial to Evaluate the Safety and Tolerability of TQB3911 Tablets in Patients With BCR::ABL Fusion Gene Positive Leukemia |
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| Not yet recruiting | 1 | 120 | RoW | TQB3911 tablets | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Chronic Myelogenous Leukemia | 09/26 | 12/26 | | |
NCT05106868: Acupuncture for Patients With Major Depressive Disorder |
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| Not yet recruiting | N/A | 123 | NA | acupuncture | Chengdu University of Traditional Chinese Medicine | Major Depressive Disorder | 12/22 | 06/23 | | |
VR-TSP, NCT06574451: Effectiveness and Safety of Adjuvant Software Based on Virtual Reality for Post-thoracoscopic Surgery Pain |
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| Recruiting | N/A | 215 | RoW | VR-assisted postoperative analgesia | Guangdong Provincial People's Hospital, Guang Dong Liang Zi Health Consulting Co., Ltd, Guang Dong, China., Tianjin Medical University General Hospital, Ruijin Hospital, Maoming People's Hospital | Acute Postoperative Pain, Video-assisted Thoracic Surgery, Virtual Reality | 04/25 | 04/25 | | |
NCT04948528: Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for Upper Tract Urothelial Carcinoma Detection |
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| Recruiting | N/A | 490 | RoW | Active Comparator: Surgery Pathology or Cystoscopy, Active Comparator: Clinical Diagnosis | AnchorDx Medical Co., Ltd., Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Peking University First Hospital, Peking University Third Hospital, Peking Union Medical College Hospital, The Affiliated Hospital of Qingdao University, First Affiliated Hospital, Sun Yat-Sen University, Sir Run Run Shaw Hospital, The First Affiliated Hospital of Zhengzhou University | Upper Tract Urothelial Carcinoma | 06/23 | 12/23 | | |
NCT04744506: Targeted Resection of Axillary Metastatic Lymph Nodes After Breast Cancer Neoadjuvant Chemotherapy |
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| Not yet recruiting | N/A | 126 | RoW | Tissue Marker Clip, Carbon Nanoparticle Suspension Injection | Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Natural Science Foundation of China | Breast Cancer, Surgery, Lymph Node Metastases | 07/28 | 07/29 | | |
NCT04966949: Lateral Prostate Capsule Sparing Versus Nerve Sparing Robot-assisted Radical Cystectomy-orthotopic Ileal Neobladder for Bladder Cancer in the Male |
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| Not yet recruiting | N/A | 100 | RoW | lateral prostate capsule sparing or neurovascular bundles sparing | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, The Seventh Affiliated Hospital, Sun Yat-sen University | Bladder Cancer | 08/23 | 08/23 | | |
ONAC, NCT06155305: Organoids Based Drug Sensitivity in Neoadjuvant Chemotherapy of Breast Cancer |
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| Recruiting | N/A | 58 | RoW | Biopsy | Second Affiliated Hospital, School of Medicine, Zhejiang University | Organoids, Breast Cancer, Neoadjuvant Chemotherapy | 12/25 | 12/25 | | |
NCT06658080: Drug Sensitivity of Hydrothorax and Ascite Organoids from Breast Cancer |
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| Recruiting | N/A | 90 | RoW | organoid drug test | Second Affiliated Hospital, School of Medicine, Zhejiang University | Breast Cancer Metastatic, Hydrothorax, Ascites, Organoids, Drug Evaluation | 10/26 | 10/27 | | |
NCT06741540: Effects of TDCS Intervention on Neoadjuvant Chemotherapy in Breast Cancer Patients with Mild to Moderate Depression |
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| Not yet recruiting | N/A | 60 | NA | tDCS | Second Affiliated Hospital, School of Medicine, Zhejiang University | Breast Cancer | 12/26 | 12/26 | | |
NCT04966975: Effect and Prognosis of Immunohistochemical Biomarkers Changes in Patients With Bladder Cancer After Neoadjuvant Chemotherapy |
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| Not yet recruiting | N/A | 60 | NA | neoadjuvant chemotherapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Shantou Central Hospital | Bladder Cancer | 08/22 | 08/22 | | |
NCT04966130: Effect of Urinary Indwelling Time on Early Continence After Robot-assisted Radical Cystectomy With Orthotopic Ileal Neobladder. |
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| Not yet recruiting | N/A | 96 | NA | | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University | Muscle-Invasive Bladder Carcinoma | 08/22 | 08/22 | | |
NCT04966962: Establishment and Validation of an Early Diagnostic Model for Bladder Cancer Based on Serum and Urine Metabolomics |
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| Not yet recruiting | N/A | 180 | NA | serum and urine metabolomics | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, The Seventh Affiliated Hospital, Sun Yat-sen University | Bladder Cancer | 08/22 | 08/22 | | |
NCT04958343: Application and Clinical Effectiveness of Pelvic Reconstruction in Robot-assisted Radical Cystectomy-orthotopic Ileal Neobladder in the Male |
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| Not yet recruiting | N/A | 100 | RoW | pelvic reconstruction | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, The Seventh Affiliated Hospital, Sun Yat-sen University | Bladder Cancer | 07/23 | 07/23 | | |
NCT04958330: Lateral Prostate Capsule Sparing Versus Non Nerve Sparing Robot-assisted Radical Cystectomy-orthotopic Ileal Neobladder for Bladder Cancer in the Male |
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| Not yet recruiting | N/A | 100 | RoW | lateral prostate capsule sparing | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, The Seventh Affiliated Hospital, Sun Yat-sen University | Bladder Cancer | 07/23 | 07/23 | | |
NCT05018429: Nerve Sparing Versus Non Nerve Sparing Robot-assisted Radical Cystectomy-orthotopic Ileal Neobladder for Bladder Cancer in the Male |
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| Not yet recruiting | N/A | 100 | RoW | nerve sparing | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Shantou Central Hospital | Bladder Cancer | 09/23 | 09/23 | | |
| Yan, Min |
NCT04682782: Intraoperative Small-dose Esketamine Infusion for Pain Control in Burn Patients |
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| Recruiting | 4 | 26 | RoW | Esketamine, Saline, Placebo | Second Affiliated Hospital, School of Medicine, Zhejiang University | Burns | 12/20 | 12/20 | | |
NCT05035069: Efficacy and Safety of Ciprofol Compared to Propofol for Nonintubated General Anesthesia in Patients Undergoing TAVR |
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| Not yet recruiting | 4 | 24 | RoW | Ciprofol, Propofol | Haisco Pharmaceutical Group Co., Ltd. | Anesthesia, General | 02/22 | 02/22 | | |
NCT04919174: A Randomized Single-blind Clinical Trial of the Efficacy and Safety of Remimazolam in Painless Bronchoscopy |
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| Recruiting | 4 | 364 | RoW | Remimazolam, Remifentanil, Dexmedetomidine | Second Affiliated Hospital, School of Medicine, Zhejiang University | Bronchoscopy, Sedation | 04/22 | 10/22 | | |
NCT04664530: The Study on the Esketamine in the Treatment of Postherpetic Neuralgia |
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| Recruiting | 4 | 48 | RoW | esketamine, Saline | Second Affiliated Hospital, School of Medicine, Zhejiang University | Postherpetic Neuralgia, Esketamine | 06/22 | 12/23 | | |
NCT05881291: Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement |
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| Completed | 4 | 124 | RoW | ciprofol, alfentanil, propofol | Second Affiliated Hospital, School of Medicine, Zhejiang University | Hemodynamics, Transcatheter Aortic Valve Replacement, General Anesthesia, Post-induction Hypotension | 07/24 | 07/24 | | |
RC48-C012, NCT04400695: A Study of RC48-ADC for the Treatment of Locally Advanced or Metastatic Breast Cancer With Low Expression of HER2 |
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| Recruiting | 3 | 366 | RoW | RC48-ADC, RC48, Paclitaxel Injection, Taxol, Docetaxel Injection, Taxotere, Vinorelbine Tartrate Injection, Navelbine, Capecitabine Tablets, Xeloda | RemeGen Co., Ltd. | Breast Cancer | 06/24 | 12/24 | | |
| Active, not recruiting | 3 | 466 | Europe, Canada, Japan, US, RoW | tucatinib, ONT-380, placebo, T-DM1, Kadcyla | Seagen Inc., Seagen Inc., Seattle Genetics, Inc., Seagen Inc | HER2-positive Breast Cancer | 06/23 | 10/27 | | |
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TORCHLIGHT, NCT04085276: Toripalimab in Combination With Nab-Paclitaxel For Patients With Metastatic or Recurrent Triple-Negative Breast Cancer (TNBC) With or Without Systemic Treatment |
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| Active, not recruiting | 3 | 531 | RoW | JS001, Nab-Paclitaxel, Placebo | Shanghai Junshi Bioscience Co., Ltd. | Triple-Negative Breast Cancer | 12/24 | 12/25 | | |
NCT06254742: A Trial of HHPG-19K Injection and Auto-HHPG-19K Injection in Prevention of Chemotherapy-related Moderate to Severe Neutropenia of Patients With Nonmyeloid Malignancies |
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| Not yet recruiting | 3 | 107 | RoW | HHPG-19K Injection | Jiangsu HengRui Medicine Co., Ltd. | Patients With Nonmyeloid Malignancies Receiving Antineoplastic Therapy Based on Chemotherapy Regimens at Moderate to High Febrile Neutropenia (FN) Risk | 05/24 | 06/24 | | |
NCT06419621: PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic Triple-negative Breast Cancer |
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| Recruiting | 3 | 360 | RoW | PM8002, Nab-Paclitaxel, Placebo | Biotheus Inc. | Triple Negative Breast Cancer(TNBC) | 07/27 | 07/28 | | |
TQB2102-III-01, NCT06561607: A Clinical Trial to Evaluate the Efficacy and Safety of TQB2102 for Injection Versus Investigator-Selected Chemotherapy in HER2 Low-Expressing Recurrent/Metastatic Breast Cancer |
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| Not yet recruiting | 3 | 542 | RoW | TQB2102 for Injection, Chemotherapy drug (Capecitabine/Paclitaxel/Albumin Paclitaxel) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Breast Cancer | 01/27 | 12/28 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
| Active, not recruiting | 3 | 158 | RoW | Roxadustat, FG-4592, Evrenzo | Second Affiliated Hospital, School of Medicine, Zhejiang University | Perioperative Anemia | 11/26 | 05/27 | | |
| Recruiting | 3 | 314 | RoW | Investigational drug: Recombinant Anti-HER2 Humanized Monoclonal Antibody - Monomethyl Auristatin F Conjugates for Injection (FS-1502), Control drug: Trastuzumab emtansine (Kadcyla, T-DM1) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | Breast Cancer | 07/25 | 01/26 | | |
| Active, not recruiting | 2/3 | 549 | Europe, RoW | Oral paclitaxel, Liporaxel®, Paclitaxel injection, Taxol® | Daehwa Pharmaceutical Co., Ltd., Daehwa pharmaceutical Co., Ltd. | Recurrent or Metastatic Breast Cancer | 02/24 | 12/25 | | |
RC48-C006, NCT03500380: A Study of RC48-ADC Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer With or Without Liver Metastases |
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| Active, not recruiting | 2/3 | 301 | RoW | RC48-ADC, RC48, Lapatinib, Capecitabine | RemeGen Co., Ltd. | Breast Neoplasms, Breast Diseases, Capecitabine, HER2-positive Breast Cancer, HER2 Positive Breast Carcinoma, HER2-positive Advanced Breast With Liver Metastases | 07/24 | 12/24 | | |
PERMEATE, NCT03691051: A Study of Pyrotinib Plus Capecitabine in Patients With Brain Metastases From HER2-positive Metastatic Breast Cancer |
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| Active, not recruiting | 2 | 78 | RoW | Pyrotinib plus Capecitabine, Irene | Henan Cancer Hospital | HER2 Positive Metastatic Breast Cancer | 04/21 | 12/24 | | |
DAP-Her-01, NCT04293276: Study to Evaluate the Efficacy and Safety of SHR6390 Combined With Pyrotinib in HER2+ Advanced Breast Cancer |
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| Active, not recruiting | 2 | 41 | RoW | Pyrotinib, SHR6390 | Henan Cancer Hospital, Jiangsu HengRui Medicine Co., Ltd. | Metastatic Breast Cancer | 08/21 | 05/23 | | |
NCT04681287: Exploratory Study of Advanced Breast Cancer in HER2 Positive Patients With Failure of Multi-line Therapy Treated by Combination of Inetetamab (Cipterbin) + PD-1 Inhibitor Combined With Utidelone. |
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| Active, not recruiting | 2 | 46 | RoW | inetetamab and PD-1 inhibitor combined with chemotherapy. | Henan Cancer Hospital | HER2 Positive Metastatic Breast Cancer | 11/21 | 12/24 | | |
| Recruiting | 2 | 120 | RoW | TQB3616 capsules, Fulvestrant injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | HR-positive, HER2-negative Advanced Breast Cancer | 01/23 | 01/23 | | |
NCT05394285: A Clinical Study of Hetrombopag Olamine Tablets for Thrombocytopenia Induced by Chemotherapy in Advanced Breast Cancer |
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| Recruiting | 2 | 60 | RoW | Hetrombopag, rh-TPO | Henan Cancer Hospital, Jiangsu HengRui Medicine Co., Ltd. | Breast Cancer | 12/24 | 12/24 | | |
NCT06176534: Combination Followed by Maintenance Chemotherapy Versus CDK4/6 Inhibitor Combined With Endocrine Therapy for HR Low/HER2-negative Advanced Breast Cancer: a Prospective, Randomized, Open-label Phase Ⅱ Clinical Trial |
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| Recruiting | 2 | 240 | RoW | Experimental: chemotheyapy, Vinorelbine 25mg/m2，day 1 and day 8 + Capecitabine 2000mg/m2，from day1 to DAY 14, Active Comparator: endocrine therapy | Henan Cancer Hospital | Advanced Breast Cancer, Treatment, HR Low/HER2 Negative | 12/25 | 12/26 | | |
NCT05970432: A Clinical Study of TQH2722 Injection in the Treatment of Moderate to Severe Atopic Dermatitis |
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| Recruiting | 2 | 160 | RoW | TQH2722 injection 300mg-150mg, TQH2722 injection 600mg-300mg, TQH2722 injection 900mg-450mg, TQH2722 injection matching Placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Atopic Dermatitis | 03/24 | 03/24 | | |
NCT05336721: A Phase II Study of Chiauranib in Combine With Capecitabine in TNBC |
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| Terminated | 2 | 9 | RoW | Chiauranib, capecitabine | Chipscreen Biosciences, Ltd. | Triple-negative Breast Cancer | 10/24 | 11/24 | | |
| Recruiting | 2 | 100 | RoW | utidelone, Bevacizumab | Henan Cancer Hospital | Breast Cancer | 05/24 | 05/24 | | |
NCT05328440: Treatment of Dalpiciclib Combined With Pyrotinib for Trastuzumab-sensitive HER2+ Advanced Breast Cancer(DAP-Her-02) |
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| Recruiting | 2 | 120 | RoW | Pyrotinib Maleate, Pyrotinib, Dalpiciclib Isethionate Tablets, SHR6390, Inetetamab, Fulvestrant | Henan Cancer Hospital, Jiangsu HengRui Medicine Co., Ltd. | Breast Neoplasms | 06/24 | 01/26 | | |
NCT06458413: Utidelone Capsule Plus Capecitabine (CAP) for Metastatic Breast Cancer |
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| Recruiting | 2 | 40 | RoW | Utidelone Capsule Plus Capecitabine | Min Yan, MD, Beijing Biostar Pharmaceuticals Co., Ltd. | Breast Cancer Recurrent | 06/25 | 12/25 | | |
HNCH-MBC15-BM06, NCT06598046: A Single-arm, Prospective Phase Ⅱ Clinical Study of Utidelone Combined with Capecitabine in the Treatment of Active Brain Metastasis of TNBC |
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| Recruiting | 2 | 48 | RoW | Utidelone and capecitabine | Henan Cancer Hospital | Metastatic Breast Cancer | 06/26 | 08/26 | | |
NCT05296577: Anlotinib Combination With Vinorelbine in the HER2- Advanced Breast Cancer |
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| Recruiting | 2 | 134 | RoW | anlotinib and vinorelbine, AL3818 and vinorelbine, Vinorelbine injection, vinorelbine | Henan Cancer Hospital | Breast Cancer | 09/24 | 12/24 | | |
NCT05769010: Study of SHR-A1811 in HER2-expression Advanced Breast Cancer with Brain Metastases |
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| Recruiting | 2 | 125 | RoW | SHR-A1811, Pyrotinib, Bevacizumab | Henan Cancer Hospital | Metastatic Breast Cancer | 10/25 | 04/26 | | |
NCT05872347: Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases. |
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| Recruiting | 2 | 52 | RoW | SPH4336 Tablets | Shanghai Pharmaceuticals Holding Co., Ltd | Breast Cancer Brain Metastases | 12/25 | 12/25 | | |
NCT06208410: A Clinical Study of JS105 in Combination With Other Anti-tumor Therapies in Patients With Solid Tumors |
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| Recruiting | 1/2 | 306 | RoW | JS105, Fulvestrant injection, Dalpiciclib Isetionate Tablets, Toripalimab Injection, Paclitaxel for Injection (Albumin Bound), Fluzoparib Capsules, Pyrotinib Maleate Tablets, Capecitabine Tablets | Risen (Suzhou) Pharma Tech Co., Ltd. | Advanced Solid Tumors | 02/26 | 02/26 | | |
NCT06464055: A Study of GQ1010 in Subjects With Advanced Solid Tumors |
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| Recruiting | 1/2 | 220 | RoW | Dose Escalation, Dose Expansion1, Dose Expansion2, phase II | GeneQuantum Healthcare (Suzhou) Co., Ltd. | Advanced Malignant Solid Tumors | 05/28 | 12/28 | | |
NCT05176080: Famitinib Plus SHR6390 and Endocrine Therapy in the Treatment of HR-positive, HER2-negative Advanced Breast Cancer |
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| Terminated | 1/2 | 46 | RoW | Famitinib, SHR6390, Dalpiciclib, Fulvestrant | Henan Cancer Hospital | Metastatic Breast Cancer | 07/24 | 07/24 | | |
KL264-01, NCT04152499: Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies |
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| Recruiting | 1/2 | 1300 | Canada, US, RoW | SKB264 | Klus Pharma Inc. | Epithelial Ovarian Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Small-Cell Lung Cancer, Endometrial Carcinoma, Head and Neck Squamous Cell Carcinoma, Breast Cancer | 08/25 | 07/26 | | |
NCT06679036: A Trial of HRS-2189 in Combination With Fluvastatin±HRS-6209, or HRS-8080±HRS-6209, or HRS-6209+HRS-1358 in Breast Cancer Patients |
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| Not yet recruiting | 1/2 | 300 | RoW | HRS-2189, Fluvustat, HRS-8080, HRS-6209, HRS-1358 | Shandong Suncadia Medicine Co., Ltd. | Advanced Unresectable or Metastatic Breast Cancer | 10/26 | 12/26 | | |
NCT05335473: Iribrine Plus Tucidinostat in the Treatment of HR+/HER2 Advanced Breast Cancer After CDK4/6 Inhibitor Failure |
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| Recruiting | 1/2 | 87 | RoW | Eribulin and Tucidinostat | Henan Cancer Hospital | HR Positive HER2 Negative Advanced Breast Cancer | 05/25 | 11/25 | | |
NCT05438329: First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors |
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| Recruiting | 1/2 | 902 | US, RoW | DB-1305/BNT325, DB-1305/BNT325 for Injection, Pembrolizumab, BNT327 | DualityBio Inc., BioNTech SE | Advanced Solid Tumor | 06/25 | 06/25 | | |
| Recruiting | 1 | 70 | RoW | TQB3915 tablets | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Advanced Malignant Tumor | 06/23 | 06/24 | | |
NCT05245058: SPH5030 Tablets in Subjects With Advanced Her2-positive Solid Tumors |
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| Recruiting | 1 | 150 | RoW | SPH5030 tablets | Shanghai Pharmaceuticals Holding Co., Ltd | HER2-positive Advanced Solid Tumors | 12/24 | 12/24 | | |
NCT05414136: Evaluating the Safety, Tolerability, and Pharmacokinetics of BAT1006 |
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| Completed | 1 | 37 | RoW | BAT1006, Recombinant humanized anti-HER2 monoclonal antibody for injection | Bio-Thera Solutions | Advanced Solid Tumor | 06/24 | 06/24 | | |
NCT05473624: Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 153 | RoW | HRS-1167 | Jiangsu HengRui Medicine Co., Ltd. | Advanced Solid Tumors | 12/24 | 12/24 | | |
CGCT-01, NCT02130752: Ultrasonic Scalpel vs. Monopolar Electrocautery for D2 Distal Gastric Carcinoma Surgery |
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| Recruiting | N/A | 430 | RoW | Monopolar electrocautery, Ultrasonic scalpel | West China Hospital | Gastric Cancer, Surgery, Ultrasonic Scalpel, Monopolar Electrocautery, Operation Time, Blood Loss, Surgical, Quality of Life, External Causes of Morbidity and Mortality | 10/19 | 10/22 | | |
NCT04613869: The Effect of Esketamine on Patients Undergoing Tumor Surgery |
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| Active, not recruiting | N/A | 282 | RoW | High-dose Esketamine hydrochloride+Hydromorphone, Low-dose Esketamine hydrochloride+Hydromorphone, Hydromorphone | Second Affiliated Hospital, School of Medicine, Zhejiang University | Tumor Surgery | 08/21 | 10/21 | | |
NCT04860648: Lung Ultrasound Guided Prevention of Postoperative Pulmonary Complications in Moderate to High Risk Patients |
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| Not yet recruiting | N/A | 592 | RoW | lung ultrasound, doctors' clinical decision | Second Affiliated Hospital, School of Medicine, Zhejiang University | Postoperative Respiratory Complication | 12/21 | 03/22 | | |
NCT05267145: The Protection of ACD III on Erythrocytes in Intraoperative Blood Salvage During Cardiopulmonary Bypass |
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| Not yet recruiting | N/A | 60 | RoW | blood preservation solution III | Second Affiliated Hospital, School of Medicine, Zhejiang University | Red Blood Cell Disorder | 06/22 | 08/22 | | |
NCT04934657: Association of Perioperative Daily Steps and Postoperative Recovery Among Surgical Patients |
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| Recruiting | N/A | 487 | RoW | no intervention | Second Affiliated Hospital, School of Medicine, Zhejiang University | Postoperative Recovery | 08/22 | 12/22 | | |
NCT05130333: The Clinical Research of Needle Electrodes Used in Bispectral Index to Monitor the Depth of Anesthesia |
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| Not yet recruiting | N/A | 120 | RoW | No intervention | Second Affiliated Hospital, School of Medicine, Zhejiang University | Intraoperative Monitoring, Depth of Anesthesia | 10/22 | 02/23 | | |
NCT05338554: Optimize the Effects of Repetitive Transcranial Magnetic Stimulation on Neuropathic Pain |
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| Completed | N/A | 40 | RoW | Repetitive transcranial magnetic stimulation | Second Affiliated Hospital, School of Medicine, Zhejiang University | Neuropathic Pain, Repetitive Transcranial Magnetic Stimulation | 12/22 | 12/22 | | |
NCT05360030: Mechanism of Analgesic Effect on Prolonged Continuous Theta Burst Stimulation |
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| Completed | N/A | 45 | RoW | Naloxone, Saline, Ketamine Hydrochloride, pcTBS of M1, pcTBS of DLPFC, SHAM stimulation | Second Affiliated Hospital, School of Medicine, Zhejiang University | Chronic Pain, rTMS | 12/22 | 12/22 | | |
NCT05168319: Effects and Mechanism of Prolonged Continuous Theta Burst Stimulation on Neuropathic Pain |
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| Completed | N/A | 94 | RoW | Repetitive transcranial magnetic stimulation, Sham stimulation | Second Affiliated Hospital, School of Medicine, Zhejiang University | Neuropathic Pain, Repetitive Transcranial Magnetic Stimulation | 12/22 | 01/23 | | |
NCT05706441: Lung and Diaphragm Ultrasound Evaluation During Weaning From Mechanical Ventilation in COVID-19 Patients |
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| Completed | N/A | 35 | RoW | Point-of-Care Ultrasound | Second Affiliated Hospital, School of Medicine, Zhejiang University | Weaning, COVID-19, Lung Ultrasound, Diaphragm Ultrasound | 03/23 | 03/23 | | |
| Recruiting | N/A | 1250 | RoW | EEG(Electroencephalogram) change | Air Force Military Medical University, China | Aging, Postoperative Cognitive Dysfunction, EEG With Periodic Abnormalities | 03/23 | 04/23 | | |
NCT05713305: Effect of an Online Self-help Psychological Intervention on Non-ICU Specialty Care During the COVID-19 Outbreak |
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| Completed | N/A | 110 | RoW | Online-based self-help psychological intervention, Provide online mental health knowledge | Second Affiliated Hospital, School of Medicine, Zhejiang University | SARS-CoV-2 Infection, Staff Attitude, Anxiety, Mental Health Issue | 06/23 | 06/23 | | |
NCT05637164: Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for Preventing Post-induction Hypotension in Elderly Patients Undergoing Major Abdominal Surgery |
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| Recruiting | N/A | 40 | RoW | norepinephrine bitartrate | Second Affiliated Hospital, School of Medicine, Zhejiang University | Norepinephrine, Post-induction Hypotension | 05/23 | 05/23 | | |
NCT05871203: Changes in Gene Expression and Prognosis of Blood Immune Cells After Cardiopulmonary Bypass Surgery |
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| Recruiting | N/A | 12 | RoW | Gene sequencing | Second Affiliated Hospital, School of Medicine, Zhejiang University | Acute Kidney Injury | 06/23 | 07/23 | | |
NCT04879602: Effect of Suctioning by Bronchoscope on Postoperative Pulmonary Complications Among Patients With SCI in the PACU |
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| Recruiting | N/A | 24 | RoW | suction with bronchoscopy | Second Affiliated Hospital, School of Medicine, Zhejiang University | Spinal Cord Injuries | 12/23 | 12/23 | | |
