Medicines Evaluation Unit
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 32 Trials 
71 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Brown, Cynthia J
ELEVAATE, NCT05856331: Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Recruiting
2
90
Europe, US, RoW
INBRX-101, Zemaira
Inhibrx Biosciences, Inc
Alpha 1-Antitrypsin Deficiency, Emphysema
05/25
06/25
NCT04798014: HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy

Completed
N/A
860
US
Indiana University, Folia Health, Cystic Fibrosis Foundation
Cystic Fibrosis
08/23
08/23
HOPeCF, NCT06296394: Health Outcomes of Parents With Cystic Fibrosis-Aim 2

Recruiting
N/A
146
US
Parenthood
University of Pittsburgh, Cystic Fibrosis Foundation, National Heart, Lung, and Blood Institute (NHLBI)
Cystic Fibrosis, Parenthood Status
02/30
02/31
Contact, Use Central
NCT03684018 / 2018-003430-33: Two Dose Levels of Privigen in Pediatric CIDP

Recruiting
4
30
US
IgPro10, Privigen
CSL Behring
Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
12/29
12/29
NCT04167514: Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone (BMT CTN 1705)

Active, not recruiting
3
136
US
Alpha-1 antitrypsin (AAT), Alpha-1 proteinase inhibitor (A1-P1), Placebo
CSL Behring, Blood and Marrow Transplant Clinical Trials Network, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI)
Graft Versus Host Disease (GVHD)
05/24
05/24
RECLAIIM, NCT04044690 / 2018-003171-35: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of IgPro20 in Adults With Dermatomyositis (DM)

Active, not recruiting
3
126
Europe, Japan, US, RoW
human immunoglobulin G, IgPro20, Hizentra, Placebo
CSL Behring, CSL Behring LLC, 1020 First Avenue, King of Prussia, PA 19406
Dermatomyositis
06/24
11/27
NCT05819775: CSL312_3003 Safety and Pharmacokinetic Study in Subjects 2 to 11 Years of Age With Hereditary Angioedema

Recruiting
3
20
Europe, Canada, US, RoW
CSL312, Garadacimab
CSL Behring
Hereditary Angioedema (HAE)
11/26
11/26
IMAGINE, NCT03744910 / 2018-003682-34: Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients

Terminated
3
194
Europe, Canada, US, RoW
Clazakizumab, Physiologic saline solution
CSL Behring, ICON Clinical Research
Antibody-mediated Rejection
04/24
04/24
NCT06003387: Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

Recruiting
3
35
Canada, US, RoW
CSL222 (AAV5-hFIXco-Padua), Etranacogene dezaparvovec
CSL Behring
Hemophilia B
10/28
10/28
MODULAATE, NCT03805789: The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-Versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant

Recruiting
2/3
310
Europe, Japan, US, RoW
Alpha-1 antitrypsin (AAT), Alpha-1 proteinase inhibitor, Placebo
CSL Behring
Acute-graft-versus-host Disease
09/25
03/27
NCT05485961: Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

Enrolling by invitation
2/3
2310
Europe, Canada, US, RoW
CSL300, Clazakizumab, Placebo
CSL Behring
Atherosclerotic Cardiovascular Disease, End Stage Kidney Disease
12/28
12/28
NCT01294020 / 2010-020925-42: Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Active, not recruiting
2
81
Europe, RoW
Tacrolimus, Prograf, FK506, Tacrolimus prolonged release, FK506E, MR4, Advagraf, tacrolimus modified release, Astagraf XL, Graceptor, Prograf XL
Astellas Pharma Europe Ltd.
Intestine Transplantation, Kidney Transplantation, Lung Transplantation, Liver Transplantation, Heart Transplantation
10/15
05/26
STARBORN-1, NCT05871970: Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age

Recruiting
2
38
US
TARA-002
Protara Therapeutics
Lymphatic Malformation
12/25
05/26
ADVANCED-2, NCT05951179: Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

Recruiting
2
127
US, RoW
TARA-002
Protara Therapeutics
Non-muscle Invasive Bladder Cancer
05/30
08/30
NCT04446000: Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous CSL730 in Healthy Adult Subjects

Terminated
1
52
Europe
CSL730, Recombinant trivalent human IgG1 Fc multimer, Placebo
CSL Behring
Immune Complex-mediated Autoimmune Diseases
03/23
03/23
NCT05653713: Effects of CSL324 in the Lung After Segmental Challenge

Completed
1
40
Europe
CSL324, Recombinant anti-granulocyte colony-stimulating factor (G-CSF) receptor monoclonal antibody (mAb), Placebo
CSL Behring
Healthy Volunteers
07/23
07/23
NCT04082754: A Clinical Study to Test the Safety, Exposure, and Pharmacodynamic Markers of CSL311 in Patients With Mild-to-moderate Asthma and in Healthy Volunteers

Completed
1
78
Europe
Human beta common receptor antagonist monoclonal antibody, CSL311, Placebo
CSL Behring
Asthma
11/23
11/23
ADVANCED-1, NCT05085990: Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

Recruiting
1
12
US
TARA-002
Protara Therapeutics
Non-muscle Invasive Bladder Cancer
06/24
08/24
ADVANCED-1, NCT05085977: Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (Phase 1a)

Recruiting
1
18
Europe, US, RoW
TARA-002
Protara Therapeutics
Non-muscle Invasive Bladder Cancer
06/24
07/24
NCT05937581: First-In-Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Escalating Single And Multiple Doses Of CSL040 In Healthy Subjects

Recruiting
1
60
RoW
CSL040, Placebo
CSL Behring
Complement Deficiencies
03/25
03/25
THRIVE-1, NCT05011370: Prevalence of Liver Disease in Patients Dependent on Parenteral Nutrition

Completed
N/A
80
Europe, US
Protara Therapeutics
Intestinal Failure-associated Liver Disease
06/23
06/23
IX-TEND 4001, NCT06008938: An Observational Cohort Study to Characterize the Effectiveness and Safety of HEMGENIX® in Patients With Hemophilia B

Recruiting
N/A
500
US
HEMGENIX, Etranacogene dezaparvovec, Factor IX (FIX)
CSL Behring
Hemophilia B
08/43
08/43
Singh, David
KN-002, NCT05006521: Single and Multiple Ascending Dose Study of

Active, not recruiting
1
117
Europe
KN-002
Kinaset Therapeutics Inc
Asthma COPD
12/23
04/24
EPS ARREST, NCT03079414: The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest

Recruiting
N/A
100
Canada, US, RoW
Invasive Electrophysiology Study
Western University, Canada, Canadian Institutes of Health Research (CIHR)
Sudden Cardiac Death
03/23
05/23
NCT04088071: Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation

Recruiting
N/A
15000
US
Catheter ablation
Heart Rhythm Clinical and Research Solutions, LLC, Biosense Webster, Inc.
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
12/27
12/27
Singh, Dave
TRECOS, NCT06264674: Comparison Between CHF5993 pMDI 200/6/12,5mg HFA-152a VS CHF5993 pMDI 200/6/12,5mg HFA-134a in Subjects With Asthma (Trecos)

Recruiting
3
790
Europe
CHF5993 200/6/12.5 μg pMDI HFA-152a, HFA-152a propellant, Inhaler CHF5993 200/6/12.5 μg pMDI HFA-134a, HFA-134a propellant
Chiesi Farmaceutici S.p.A.
Asthma
08/24
09/25
COURSE, NCT04039113 / 2019-001363-67: Tezepelumab COPD Exacerbation Study

Calendar Jan 2024 - Dec 2024: Data from COURSE trial for COPD
Completed
2
337
Europe, Canada, US, RoW
Tezepelumab, Placebo
AstraZeneca, Amgen
Chronic Obstructive Pulmonary Disease (COPD)
11/23
01/24
NCT06166056: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Recruiting
1/2
45
Europe
CHF6333, CHF6333 Placebo
Chiesi Farmaceutici S.p.A.
Bronchiectasis
06/25
06/25
NCT04769869: A Clinical Trial in Healthy Volunteers and Patients With Mild Asthma to Investigate a New Medicine (AZD4604) for the Treatment of Asthma

Completed
1
110
Europe
AZD4604 for inhalation via DPI, Placebo for AZD4604 for inhalation via DPI, AZD4604 for IV administration, AZD4604 for oral administration
AstraZeneca
Asthma
01/23
01/23
NCT05195008: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics, With Target Occupancy Study of BIIB113 in Healthy Participants

Completed
1
72
Europe
BIIB113, BIIB113-Matching Placebo, 11^C]BIO-1819578
Biogen
Healthy Volunteer
07/23
07/23
SPYVAC01, NCT06145178: A Study of Human Cytomegalovirus (HCMV) Vaccine SPYVLP01 With and Without Adjuvants

Recruiting
1
120
Europe
SPYVAC01
SpyBiotech Limited
Cytomegalovirus Infections
04/25
04/25
NCT05965089: A First in Human Study of AX-202 in Healthy Subjects and Patients With Psoriasis.

Recruiting
1
58
Europe
Placebo, AX-202
Arxx Therapeutics
Healthy Volunteers, Mild to Moderate Psoriasis
07/24
07/24
Wiesel, Philippe
NCT05843578: STENOVA - A Study to Evaluate Safety, Tolerability, PK and PD of AGMB-129 in Patients With Fibrostenotic Crohn's Disease

Recruiting
2
90
Europe, Canada, US
AGMB-129, Placebo
Agomab Spain S.L.
Fibrostenotic Crohn's Disease
12/25
12/25
NCT05937386: Drug-Drug Interaction Study With AGMB-129 and Midazolam in Healthy Participants

Completed
1
14
Europe
AGMB-129, MDZ
Agomab Spain S.L.
Healthy Volunteers
09/23
09/23
NCT06181370: Phase I Study to Assess Safety, Tolerability, PK and PD of AGMB-447 in Healthy Participants and Participants With IPF

Recruiting
1
76
Europe
AGMB-447, placebo
Agomab Spain S.L.
IPF
03/25
03/25
NCT06397508: Relative Bioavailability and Effect of Food Study With AGMB-129 in Healthy Participants

Completed
1
25
Europe
AGMB-129
Agomab Spain S.L.
Healthy Volunteers
05/24
05/24
Dilling, Daniel
IMPALA-2, NCT04544293 / 2020-001263-85: Clinical Trial of Inhaled Molgramostim Nebulizer Solution in Autoimmune Pulmonary Alveolar Proteinosis (aPAP)

Active, not recruiting
3
160
Europe, Canada, Japan, US, RoW
Molgramostim, Recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF), Placebo
Savara Inc., Savara ApS,
Autoimmune Pulmonary Alveolar Proteinosis
06/24
06/25
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis

Calendar Apr 2024 - Sep 2024: Topline data from TETON trial for IPF
Hourglass Jan 2023 - Mar 2023 : Enrollment completion of TETON trial for IPF
Recruiting
3
576
Canada, US
Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer
United Therapeutics
Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease
06/25
06/25
MILED, NCT03150914: Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial

Recruiting
3
60
US
Sirolimus, Rapamycin
University of Cincinnati, National Heart, Lung, and Blood Institute (NHLBI), National Center for Advancing Translational Sciences (NCATS), The LAM Foundation
LAM, Lymphangioleiomyomatosis
06/25
06/25
PRECISIONS, NCT04300920: Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection () Trial

Active, not recruiting
3
202
US
N-acetyl cysteine, NAC, Placebo
Weill Medical College of Cornell University, University of Virginia, University of Michigan, Pulmonary Fibrosis Foundation, University of Washington, National Heart, Lung, and Blood Institute (NHLBI), Three Lakes Foundation
Idiopathic Pulmonary Fibrosis
12/25
12/25
TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis

Recruiting
3
698
Canada, US
Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer
United Therapeutics
Progressive Pulmonary Fibrosis, Interstitial Lung Disease
11/27
11/27
IPF COMFORT, NCT05185089: Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis

Completed
2
80
Europe, US
Orvepitant Maleate, Placebo
Nerre Therapeutics Ltd., Pharm-Olam International
Cough, Idiopathic Pulmonary Fibrosis
06/24
06/24
ELEVAATE, NCT05856331: Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Recruiting
2
90
Europe, US, RoW
INBRX-101, Zemaira
Inhibrx Biosciences, Inc
Alpha 1-Antitrypsin Deficiency, Emphysema
05/25
06/25
NCT05483907: To Evaluate the Efficacy, Safety, and Tolerability of BBT-877 in Patients With IPF

Hourglass Jul 2023 - Dec 2023 : Interim data for the treatment of IPF
Checkmark Initiation of trial in idiopathic pulmonary fibrosis
Nov 2022 - Nov 2022: Initiation of trial in idiopathic pulmonary fibrosis
Recruiting
2
120
Europe, US, RoW
BBT-877, Placebo
Bridge Biotherapeutics, Inc.
Idiopathic Pulmonary Fibrosis
11/24
12/24
NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis

Recruiting
2
100
US
TTI-101, Placebo
Tvardi Therapeutics, Incorporated
Idiopathic Pulmonary Fibrosis
03/25
03/25
ALAMO, NCT05050955: AlloSure Lung Assessment and Metagenomics Outcomes Study

Recruiting
N/A
500
US
CareDx
Lung Transplant Infection, Lung Transplant; Complications, Lung Transplant Failure and Rejection
12/28
12/28
IPF-PRO, NCT01915511: Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

Checkmark
Oct 2015 - Oct 2015: 
Recruiting
N/A
2000
US
Duke University, Boehringer Ingelheim
Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease
01/28
01/28
Brickman, Chaim M
NCT05653479: Safety and Blood Levels After a Single Injection of UPB-101 in Healthy Japanese and Non-Japanese Non-East Asian Adults

Completed
1
32
Europe
UPB-101, Formerly ASP7266
Upstream Bio Inc.
Healthy
04/23
05/23
NCT05448651: Safety and Biologic Impact (Pharmacodynamics) of Repeated Injections and Increasing Amounts of UPB-101 in Asthmatics

Completed
1
32
Europe
UPB-101, Formerly ASP7266, Placebo, 0.9% saline solution
Upstream Bio Inc.
Asthma
08/23
10/23
RenoMet, NCT03831464: Metformin as RenoProtector of Progressive Kidney Disease

Active, not recruiting
3
290
Europe
Metformin Hydrochloride, Placebo Oral Tablet
Universiteit Antwerpen, University Hospital, Antwerp
Chronic Kidney Diseases
12/24
12/24
PEPPER, NCT03334006 / 2016-001788-34: Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis

Recruiting
2
200
Europe
Pentaglobin®/Standard of Care
RWTH Aachen University, Biotest
Peritonitis, Sepsis, Septic Shock
09/27
03/28
Chaudhuri, Nazia
FGCL-3019-095, NCT04419558 / 2020-000697-22: Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Calendar Apr 2024 - Sep 2024: Topline data from ZEPHYRUS-2 trial for IPF
Terminated
3
372
Europe, US, RoW
Pamrevlumab, FG-3019, Placebo
FibroGen
Idiopathic Pulmonary Fibrosis
09/23
09/23
IPF COMFORT, NCT05185089: Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis

Completed
2
80
Europe, US
Orvepitant Maleate, Placebo
Nerre Therapeutics Ltd., Pharm-Olam International
Cough, Idiopathic Pulmonary Fibrosis
06/24
06/24
INJUSTIS, NCT03670576: It's Not JUST Idiopathic Pulmonary Fibrosis Study

Recruiting
N/A
250
Europe
Optional Bronchoscopy, Quality of Life Questionnaires, Blood Samples for Biomarkers, Home Hand Held Spirometry
University of Nottingham, Nottingham University Hospitals NHS Trust
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
11/22
11/22
Goldklang, Monica
NCT05677971: Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Recruiting
3
160
Europe, Canada, US, RoW
Fazirsiran Injection, TAK-999, ARO-AAT, ADS-001, Placebo, Sodium chloride
Takeda, Takeda Development Center Americas, Inc.
Alpha1-Antitrypsin Deficiency
03/27
03/29
ELEVAATE, NCT05856331: Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Recruiting
2
90
Europe, US, RoW
INBRX-101, Zemaira
Inhibrx Biosciences, Inc
Alpha 1-Antitrypsin Deficiency, Emphysema
05/25
06/25
NCT03823443: COPD Exacerbation Blood and Urine Biomarkers Study

Terminated
N/A
7
US
Columbia University, Alpha-1 Foundation
Chronic Obstructive Pulmonary Disease, Acute Exacerbation Copd, Alpha-1 Anti-trypsin Deficiency
08/19
01/21
A1BC, NCT05297812: Alpha-1 Antitrypsin Disease Cohort: Longitudinal Biomarker Study of Disease

Active, not recruiting
N/A
286
US
Columbia University, National Heart, Lung, and Blood Institute (NHLBI), Alpha-1 Foundation
Alpha 1-Antitrypsin Deficiency, Genetic Disease
01/27
01/27
Khan, Naimat
ELEVAATE, NCT05856331: Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Recruiting
2
90
Europe, US, RoW
INBRX-101, Zemaira
Inhibrx Biosciences, Inc
Alpha 1-Antitrypsin Deficiency, Emphysema
05/25
06/25
NCT05332704: Safety, Tolerability, PK, PD and Preliminary Efficacy of ONO-4685

Suspended
1
74
Europe, RoW
ONO-4685, Placebo
Ono Pharmaceutical Co. Ltd
Plaque Psoriasis
10/24
12/25
MEU
NCT06166056: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Recruiting
1/2
45
Europe
CHF6333, CHF6333 Placebo
Chiesi Farmaceutici S.p.A.
Bronchiectasis
06/25
06/25
Office, Recruitment and Eligibility
NCT05246670: PEA for the Relief of Chemotherapy-Induced Peripheral Neuropathy

Active, not recruiting
2
88
US
Palmidrol, N-Palmitoyl Ethanolamide, N-Palmitoylethanolamide, OptiPEA, Palmitoyl Ethanolamide, Palmitoylethanolamide, PEA, Placebo Administration, Quality-of-Life Assessment, Quality of Life Assessment
Academic and Community Cancer Research United, National Cancer Institute (NCI)
Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
08/24
02/25
KOMET-001, NCT04067336: First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
1/2
199
Europe, Canada, US
Ziftomenib
Kura Oncology, Inc.
Advanced Malignant Neoplasm, Acute Myeloid Leukemia, Mixed Lineage Leukemia, Mixed Lineage Acute Leukemia, Acute Leukemia of Ambiguous Lineage, Mixed Phenotype Acute Leukemia
09/24
09/25
REVERT, NCT05384119: Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast Cancer

Completed
1/2
6
US
TTI-101, Palbociclib, Ibrance ®, Aromatase inhibitor (AI), fulvestrant, ribociclib
Tvardi Therapeutics, Incorporated
Breast Cancer
04/24
04/24
NCT05448651: Safety and Biologic Impact (Pharmacodynamics) of Repeated Injections and Increasing Amounts of UPB-101 in Asthmatics

Completed
1
32
Europe
UPB-101, Formerly ASP7266, Placebo, 0.9% saline solution
Upstream Bio Inc.
Asthma
08/23
10/23
NCT05574933: Racism-based and Biomarkers of Stress

Completed
N/A
20
US
Rockefeller University
Racism, Stress, Psychological
04/23
04/23
NCT06146218: Compassion-Based Resiliency Training (CBRT) Intervention on Racism-based Stress

Recruiting
N/A
20
US
Contemplative-Based Resilience Training (CBRT)
Rockefeller University
Racism, Stress, Psychological
05/24
05/24
Singh, ssor Dave
NCT05448651: Safety and Biologic Impact (Pharmacodynamics) of Repeated Injections and Increasing Amounts of UPB-101 in Asthmatics

Completed
1
32
Europe
UPB-101, Formerly ASP7266, Placebo, 0.9% saline solution
Upstream Bio Inc.
Asthma
08/23
10/23
Rivera-Ortega, Pilar
NCT04533022 / 2020-000822-24: Safety, Efficacy and Pharmacokinetics of C21 in Subjects With IPF

Hourglass May 2023 - May 2023 : Safety and efficacy of AIR study in idiopathic pulmonary fibrosis
Checkmark Interim data from AIR STUDY for IPF
Nov 2022 - Nov 2022: Interim data from AIR STUDY for IPF
Checkmark Interim data from AIR STUDY for IPF
Feb 2022 - Feb 2022: Interim data from AIR STUDY for IPF
Completed
2
52
Europe, RoW
C21
Vicore Pharma AB, Orphan Reach
Idiopathic Pulmonary Fibrosis
03/24
03/24
Corral, Josie
ELEVAATE, NCT05856331: Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Recruiting
2
90
Europe, US, RoW
INBRX-101, Zemaira
Inhibrx Biosciences, Inc
Alpha 1-Antitrypsin Deficiency, Emphysema
05/25
06/25
Traux, Brendon
ELEVAATE, NCT05856331: Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Recruiting
2
90
Europe, US, RoW
INBRX-101, Zemaira
Inhibrx Biosciences, Inc
Alpha 1-Antitrypsin Deficiency, Emphysema
05/25
06/25

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