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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Creelan, Benjamin
TRIDENT-1, NCT03093116 / 2016-003616-13: A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements Jul 2023 - Dec 2023 : Approval for ROS1+ NSCLC Jan 2023 - Dec 2023 : Data readout from P1/2 TRIDENT-1 trial for ROS1 NSCLC and NTRK+ solid tumors Top line data across ROS1-positive TKI-naïve and TKI-pretreated NSCLC cohorts in TRIDENT-1 trial Apr 2022 - Apr 2022: Top line data across ROS1-positive TKI-naïve and TKI-pretreated NSCLC cohorts in TRIDENT-1 trial Presentation of Trident -1 data for the treatment of NSCLC in AACR-NCI-EORTC 2021 Oct 2021 - Oct 2021: Presentation of Trident -1 data for the treatment of NSCLC in AACR-NCI-EORTC 2021 For TKI-naive ROS1-positive NSCLC from TRIDENT-1 study Jan 2021 - Jan 2021: For TKI-naive ROS1-positive NSCLC from TRIDENT-1 study Interim data from P2 portion of P1/2 TRIDENT-1 trial for ROS-1 positive NSCLC and NTRK-positive solid tumors Aug 2020 - Aug 2020: Interim data from P2 portion of P1/2 TRIDENT-1 trial for ROS-1 positive NSCLC and NTRK-positive solid tumors From TRIDENT-1 trial [screenshot] Sep 2019 - Sep 2019: From TRIDENT-1 trial [screenshot] From P1 portion of P1/2 TRIDENT-1 trial for ROS-1 positive NSCLC and NTRK-positive solid tumors Jun 2019 - Jun 2019: From P1 portion of P1/2 TRIDENT-1 trial for ROS-1 positive NSCLC and NTRK-positive solid tumors From P1 portion of P1/2 TRIDENT-1 trial at ASCO 2019 [screenshot] May 2019 - May 2019: From P1 portion of P1/2 TRIDENT-1 trial at ASCO 2019 [screenshot] FromTRIDENT-1 trial for ROS-1 positive NSCLC and NTRK-positive solid tumors [screenshot] Sep 2018 - Sep 2018: FromTRIDENT-1 trial for ROS-1 positive NSCLC and NTRK-positive solid tumors [screenshot] From TRIDENT-1 trial in patients with advanced ALK/ROS1/NTRK+ Cancers at ASCO 2018 [screenshot] Jun 2018 - Jun 2018: From TRIDENT-1 trial in patients with advanced ALK/ROS1/NTRK+ Cancers at ASCO 2018 [screenshot] More	Recruiting	1/2	500	Europe, Canada, Japan, US, RoW	Oral repotrectinib (TPX-0005), repotrectinib	Turning Point Therapeutics, Inc., Zai Lab (Shanghai) Co., Ltd.	Locally Advanced Solid Tumors, Metastatic Solid Tumors	02/28	02/28
NCT04610658: Immune Checkpoint Inhibition With Lurbinectedin Relapsed/Recurrent SCLC	Terminated	1	9	US	Nivolumab, Opdivo, Ipilimumab, Yervoy, Lurbinectedin	H. Lee Moffitt Cancer Center and Research Institute, Bristol-Myers Squibb, Jazz Pharmaceuticals	Small-cell Lung Cancer, Relapsed Small Cell Lung Cancer, Recurrent Small Cell Lung Cancer	03/23	03/23