L'Institut National de Recherche Biomédicale RDC Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Muyembe-Tamfum, Jean-Jacques

NCT04152486: Effectiveness and Safety of a Heterologous, Two-dose Ebola Vaccine in the DRC

Active, not recruiting

20426

RoW

Ad26.ZEBOV, MVA-BN-Filo vaccine

London School of Hygiene and Tropical Medicine, Epicentre, Ministère de la Santé de la RDC, Médecins Sans Frontières, France, Coalition for Epidemic Preparedness Innovations, Janssen Vaccines & Prevention B.V., Public Health England

Ebola Virus Disease

01/22

02/22

NCT05559099: Tecovirimat for Treatment of Monkeypox Virus

Completed

597

RoW

Tecovirimat Oral Capsule, TPOXX, Placebo

National Institute of Allergy and Infectious Diseases (NIAID), Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo

Monkeypox

09/24

NCT06721585: Tecovirimat for Treatment of Monkeypox Virus - Study Extension Providing Standard of Care Only

Recruiting

N/A

400

RoW

Tecovirimat Oral Capsule [Tpoxx], TPOXX, Standard of Care (SOC)

National Institute of Allergy and Infectious Diseases (NIAID), Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo

Mpox (Monkeypox)

07/25

Bausch, Daniel

NCT04152486: Effectiveness and Safety of a Heterologous, Two-dose Ebola Vaccine in the DRC

Active, not recruiting

20426

RoW

Ad26.ZEBOV, MVA-BN-Filo vaccine

Ebola Virus Disease

01/22

02/22

Watson-Jones, Deborah :L

NCT02834637: A Dose Reduction Immunobridging and Safety Study of Two HPV Vaccines in Tanzanian Girls

Active, not recruiting

930

RoW

bivalent HPV vaccine, Cervarix, nonavalent HPV vaccine, Gardasil9

London School of Hygiene and Tropical Medicine, University of York, Institut Català d'Oncologia, National Cancer Institute (NCI), Karolinska Institutet, Technische Universität Berlin, Tanzanian National Institute for Medical Research, University of Glasgow

Human Papilloma Virus

01/20

03/27

NCT04152486: Effectiveness and Safety of a Heterologous, Two-dose Ebola Vaccine in the DRC

Active, not recruiting

20426

RoW

Ad26.ZEBOV, MVA-BN-Filo vaccine

Ebola Virus Disease

01/22

02/22

NCT05064956: Ad26.ZEBOV Booster in HIV+ Adults Previously Vaccinated With Ad26.ZEBOV/MVA-BN-Filo (EBOVAC HIV+ Booster Study)

Completed

RoW

Ad26.ZEBOV, Zabdeno®

London School of Hygiene and Tropical Medicine

Ebola Virus Disease, Ebola, Hiv

11/21

10/22

NCT05284097: Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone Study

Completed

133

RoW

Ad26.ZEBOV, MVA-BN-Filo, VAC52150

London School of Hygiene and Tropical Medicine, University of Sierra Leone, Janssen Vaccines & Prevention B.V.

Virus Diseases, Hemorrhagic Fever, Ebola, Infections, Hemorrhagic Fevers, Viral, RNA Virus Infections, Filoviridae Infections, Mononegavirales Infections, Vaccines, Immunologic Factors, Physiological Effects of Drugs, Ebola

03/23

10/24

NCT03820739: EBOVAC-Salone Extension

Completed

N/A

653

RoW

Follow-up, Blood sample collection

London School of Hygiene and Tropical Medicine, University of Sierra Leone, Janssen Vaccines & Prevention B.V., Institut National de la Santé Et de la Recherche Médicale, France, Universiteit Antwerpen

Ebola Virus Disease

06/22

07/22

HPV, NCT06129253: Global Burden Estimation of Human Papillomavirus (GLOBE-)

Recruiting

N/A

29750

RoW

Urine Sample Collection, Self-collected Vaginal Swab, Blood Samples

International Vaccine Institute, London School of Hygiene and Tropical Medicine, Karolinska Institutet, Centers for Disease Control and Prevention

HPV Infection

12/27

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Muyembe-Tamfum, Jean-Jacques

NCT04152486: Effectiveness and Safety of a Heterologous, Two-dose Ebola Vaccine in the DRC

Active, not recruiting

20426

RoW

Ad26.ZEBOV, MVA-BN-Filo vaccine

Ebola Virus Disease

01/22

02/22

NCT05559099: Tecovirimat for Treatment of Monkeypox Virus

Completed

597

RoW

Tecovirimat Oral Capsule, TPOXX, Placebo

National Institute of Allergy and Infectious Diseases (NIAID), Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo

Monkeypox

09/24

NCT06721585: Tecovirimat for Treatment of Monkeypox Virus - Study Extension Providing Standard of Care Only

Recruiting

N/A

400

RoW

Tecovirimat Oral Capsule [Tpoxx], TPOXX, Standard of Care (SOC)

National Institute of Allergy and Infectious Diseases (NIAID), Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo

Mpox (Monkeypox)

07/25

Bausch, Daniel

NCT04152486: Effectiveness and Safety of a Heterologous, Two-dose Ebola Vaccine in the DRC

Active, not recruiting

20426

RoW

Ad26.ZEBOV, MVA-BN-Filo vaccine

Ebola Virus Disease

01/22

02/22

Watson-Jones, Deborah :L

NCT02834637: A Dose Reduction Immunobridging and Safety Study of Two HPV Vaccines in Tanzanian Girls

Active, not recruiting

930

RoW

bivalent HPV vaccine, Cervarix, nonavalent HPV vaccine, Gardasil9

Human Papilloma Virus

01/20

03/27

NCT04152486: Effectiveness and Safety of a Heterologous, Two-dose Ebola Vaccine in the DRC

Active, not recruiting

20426

RoW

Ad26.ZEBOV, MVA-BN-Filo vaccine

Ebola Virus Disease

01/22

02/22

NCT05064956: Ad26.ZEBOV Booster in HIV+ Adults Previously Vaccinated With Ad26.ZEBOV/MVA-BN-Filo (EBOVAC HIV+ Booster Study)

Completed

RoW

Ad26.ZEBOV, Zabdeno®

London School of Hygiene and Tropical Medicine

Ebola Virus Disease, Ebola, Hiv

11/21

10/22

NCT05284097: Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone Study

Completed

133

RoW

Ad26.ZEBOV, MVA-BN-Filo, VAC52150

London School of Hygiene and Tropical Medicine, University of Sierra Leone, Janssen Vaccines & Prevention B.V.

03/23

10/24

NCT03820739: EBOVAC-Salone Extension

Completed

N/A

653

RoW

Follow-up, Blood sample collection

Ebola Virus Disease

06/22

07/22

HPV, NCT06129253: Global Burden Estimation of Human Papillomavirus (GLOBE-)

Recruiting

N/A

29750

RoW

Urine Sample Collection, Self-collected Vaginal Swab, Blood Samples

International Vaccine Institute, London School of Hygiene and Tropical Medicine, Karolinska Institutet, Centers for Disease Control and Prevention

HPV Infection

12/27



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