| Hagerman, Randi J |
NCT05358886: A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome |
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| Recruiting | 3 | 150 | US | BPN14770/ zatolmilast, Placebo | Tetra Discovery Partners | Fragile X Syndrome | 06/25 | 09/25 | | |
| Recruiting | 3 | 250 | Europe, US, RoW | ZYN002 - transdermal gel, cannabidiol formulated as a clear gel that can be applied to the skin (transdermal delivery), Placebo, Placebo Comparator, Matching Placebo | Zynerba Pharmaceuticals, Inc., Zynerba Pharmaceuticals, Inc. | Fragile X Syndrome | 05/25 | 05/25 | | |
NCT03479476: A Trial of Metformin in Individuals With Fragile X Syndrome |
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| Completed | 2/3 | 120 | Canada, US | Placebo Medication, Placebo, Metformin, Glumetza, Glucophage, Fortamet, Riomet | University of California, Davis, University of Alberta, St. Justine's Hospital | Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome Disorders | 05/24 | 05/24 | | |
NCT05163808: A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome |
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| Recruiting | 2/3 | 150 | US | zatolmilast, BPN14770, Placebo | Tetra Discovery Partners | Fragile X Syndrome | 09/25 | 12/25 | | |
NCT05233579: Open-Label Trial of Sulforaphane in Premutation Carriers With FXTAS |
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| Completed | N/A | 15 | US | Sulforaphane, Avmacol | University of California, Davis | Fragile X Associated Tremor/Ataxia Syndrome (Fxtas) (Diagnosis) | 01/23 | 01/23 | | |
| Fleming, Neal W |
NCT05478174: Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia |
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| Completed | 3 | 400 | US | HSK3486, Propofol, Diprivan | Haisco-USA Pharmaceuticals, Inc. | General Anesthesia | 11/23 | 11/23 | | |
NCT03075150: PVI as a Parameter to Predict Fluid Responsiveness |
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| Recruiting | N/A | 100 | US | Masimo Rainbow sensor | University of California, Davis, Masimo Corporation | Surgery | 07/19 | 07/19 | | |
NCT04730063: Evaluation of Novel Cardio-Pulmonary Physiological Monitor, the VQm PHM™, for Acute Care Medicine |
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| Recruiting | N/A | 40 | US | VQm PHM™ | Rostrum Medical Innovations Inc., University of California, Davis | Elective Procedures Requiring Mechanical Ventilation | 01/23 | 02/23 | | |
NCT05025176: Hypotension Prediction Index: Correlations Between Invasive and Non-invasive Pressure Points. |
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| Active, not recruiting | N/A | 50 | US | Non invasive arterial pressure monitoring | University of California, Davis | Hypotension | 08/25 | 08/25 | | |
| Recruiting | N/A | 150 | US | | University of California, Davis | Mechanical Ventilation | 01/25 | 01/25 | | |
| Active, not recruiting | N/A | 43 | US | Concurrent comparison | University of California, Davis | Myocardial Contraction | 01/25 | 07/25 | | |
NCT05886218: Quantitative Neuromuscular Monitoring and Gastric Bypass Surgery |
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| Recruiting | N/A | 215 | US | Quantitative Neuromuscular Function Monitoring | University of California, Davis | Sugammadex | 02/25 | 07/25 | | |
NCT01997502: Accuracy of Pulse CO-Oximetry Technology in Characterizing Noninvasive SpHb |
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| Recruiting | N/A | 300 | US | Pulse CO-Oximetry Technology, Blood draw | University of California, Davis | Surgery, Hemoglobin | 01/25 | 01/25 | | |
| Withdrawn | N/A | 40 | US | Videolaryngoscopy review. | University of California, Davis | Surgery | 06/24 | 06/24 | | |
| Apperson, Michelle |
| Recruiting | 3 | 2060 | Europe, Canada, Japan, US, RoW | Ofatumumab, Tetanus toxoid (TT) containing vaccine (Td, Tdap), 13-valent pneumococcal conjugate vaccine (13-PCV), 23-valent pneumococcal polysaccharide vaccine (23-PPV), Seasonal Quadrivalent influenza vaccine, Keyhole limpet hemocyanin (KLH) neo-antigen | Novartis Pharmaceuticals | Relapsing Multiple Sclerosis | 12/27 | 09/28 | | |
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| Liu, Hong |
| Recruiting | 4 | 1428 | RoW | Indomethacin SR, YINDUOMEIXIN, Placebos, sham | Peking Union Medical College Hospital | Acute Pancreatitis, Complication, Mortality Rate, Organ Failure, Multiple | 06/28 | 06/30 | | |
NCT04134026: Evaluate the Efficacy and Safety of HIF-PHI for the Treatment of Anemia and Risks of Cardiovascular and Cerebrovascular Events in ESRD Newly Initiated Dialysis Patients |
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| Not yet recruiting | 4 | 400 | RoW | HIF-PHI, Epoetin Alfa, Epogen | Second Xiangya Hospital of Central South University | Anemia in Incident Dialysis Patients | 10/23 | 10/24 | | |
NCT06142552: Phase 3 Clinical Project of Pegylated Recombinant Human Coagulation Factor VIII-Fc Fusion Protein |
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| Recruiting | 3 | 120 | RoW | FRSW117, Recombinant human coagulation factor Ⅷ-Fc fusion protein for injection | Jiangsu Gensciences lnc. | Severe Hemophilia A | 01/26 | 09/26 | | |
TAPIS, NCT06316570: Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Early Dual Antiplatelet Therapy, Ticagrelor and Aspirin, Placebo, Placebo of Ticagrelor and Aspirin | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 12/25 | 12/26 | | |
BENCH, NCT04939142: A Study of Evaluating the Safety and Efficacy of ATG-010, Bortezomib, and Dexamethasone (SVd) Versus Bortezomib and Dexamethasone (Vd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM) |
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| Active, not recruiting | 3 | 150 | RoW | SVd (Selinexor+Bortezomib+dexamethasone), Vd (Bortezomib+dexamethasone) | Antengene Corporation | Relapsed or Refractory Multiple Myeloma | 07/24 | 10/24 | | |
NCT05173272: Induction Chemotherapy Combined With Immunotherapy Followed by Concurrent Chemoradiation in Advanced Cervical Cancer |
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| Recruiting | 3 | 286 | RoW | Neoadjuvant Therapy, Neoadjuvant chemotherapy combined with Serplulimab, CCRT, chemoradiation, Brachytherapy | Sichuan Cancer Hospital and Research Institute | Cervical Cancer | 12/27 | 12/28 | | |
NCT04736186: Prevention and Treatment of Pyrrolitinib-associated Diarrhea |
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| Recruiting | 2/3 | 470 | RoW | Loperamide, Loperamide and golden bifid, Loperamide and montmorillonite powder | Tianjin Medical University Cancer Institute and Hospital | Breast Cancer | 10/22 | 04/23 | | |
NCT04836520: SHR6390 Combined With Anastrozole for Preoperative Treatment of Breast Cancer. |
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| Completed | 2 | 20 | RoW | SHR6390+anatrozole | Tianjin Medical University Cancer Institute and Hospital, Jiangsu HengRui Medicine Co., Ltd. | Breast Cancer | 02/23 | 03/23 | | |
NCT05641506: A Chinese Patent Medicine Yangzhengxiaoji Capsule to Improve the Nausea of Niraparib in the Maintenance Treatment in Ovarian Cancer |
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| Not yet recruiting | 2 | 50 | RoW | Yangzheng Xiaoji, Niraparib | Sichuan Cancer Hospital and Research Institute | Ovarian Cancer | 10/23 | 05/25 | | |
| Recruiting | 2 | 86 | RoW | Penpulimab, Anlotinib | Sichuan Cancer Hospital and Research Institute | Gynecological Cancer | 12/24 | 12/25 | | |
NCT04562870 / 2020-003809-60: A Study to Evaluate Single Agent Selinexor Versus Physician's Choice in Participants with Previously Treated Myelofibrosis |
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| Active, not recruiting | 2 | 112 | Europe, US, RoW | Selinexor, Physician's Choice Treatment | Karyopharm Therapeutics Inc | Myelofibrosis | 01/25 | 01/25 | | |
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| Active, not recruiting | 1/2 | 121 | RoW | CAR-BCMA T Cells | CARsgen Therapeutics Co., Ltd., Beijing Chao Yang Hospital, The First Affiliated Hospital of Soochow University, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Tianjin Medical University General Hospital, First Affiliated Hospital of Zhejiang University, Beijing Hospital, Shanghai Tongji Hospital, Tongji University School of Medicine, First Affiliated Hospital of Wenzhou Medical University, Xiangya Hospital of Central South University, Peking University People's Hospital, Qilu Hospital of Shandong University, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University | Multiple Myeloma | 12/24 | 12/25 | | |
| Recruiting | 1/2 | 430 | RoW | IBI363, IBI325, Lenvatinib | Hunan Province Tumor Hospital, Xiangya Hospital of Central South University | Advanced Solid Tumor | 12/26 | 09/28 | | |
NCT06756321: A Study of CAR T-Cells in Relapsed/Refractory Hematologic Malignancy |
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| Recruiting | 1 | 9 | RoW | anti-CD19-CAR T-cells, or anti-CD30-CAR T-cells, or anti-CD20/CD30-CAR T-cells, Fludarabine, Cyclophosphamide | Affiliated Hospital of Nantong University, Shanghai First Song Biotechnology Co., LTD | Relapsed/refractory Lymphoma, Relapsed/Refractory Leukemia | 03/25 | 03/26 | | |
NCT04993794: Additive Anti-inflammatory Action for Critically Ill Patients With Cardiovascular Surgery (Xuebijing) IV |
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| Recruiting | N/A | 200 | RoW | XueBiJing Injection, Normal saline | Nanjing Medical University | Cardiovascular Disease, Aortic Dissection, Coronary Artery Disease, Valve Heart Disease, Congenital Heart Disease, Critical Illness | 12/22 | 12/22 | | |
PANDA V, NCT04444349: Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery |
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| Recruiting | N/A | 500 | RoW | Coenzyme Q10, ubiquinone, Standard Medical Therapy | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University, Beijing Anzhen Hospital, West China Hospital, The First Affiliated Hospital of Guangzhou Medical University | Cardiovascular Disease | 12/25 | 12/25 | | |
NTU-CML-001, NCT05152537: FLOR3 Gene Polymorphism in Predicting Outcomes of Tyrosine Kinase Inhibitor（TKI）Stopping in Chronic Myeloid Leukemia |
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| Recruiting | N/A | 15 | RoW | | Affiliated Hospital of Nantong University | Folate, CML, Treatment-free Remission | 06/23 | 12/23 | | |
NCT04216823: Perfusion Index as an Objective Measure for Supraclavicular Brachial Plexus Block in Pediatric Patients |
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| Completed | N/A | 104 | RoW | perfusion index | Tongji Hospital | Supraclavicular Brachial Plexus Block | 06/23 | 06/23 | | |
NCT05686863: Remiazolam Combined With Esketamine in Painless Bidirectional Endoscopy in Children |
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| Completed | N/A | 106 | RoW | Remimazolam, Rema, Esketamine, Esket, Propofol, Prop, remifentanil, remifen | Tongji Hospital | Drug Effect | 07/23 | 07/23 | | |
PANDA, NCT04699279: Protective Effect of Statin Against Negative Cardiovascular Remodeling and Organ Dysfunction After Acute Aortic Syndrome Surgery ( III) |
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| Recruiting | N/A | 300 | RoW | Rosuvastatin 10mg | Nanjing Medical University, Beijing Anzhen Hospital, West China Hospital, The First Affiliated Hospital of Guangzhou Medical University, The Affiliated Hospital of Qingdao University Medical College | Acute Aortic Syndrome, Aortopathy | 12/24 | 12/24 | | |
NCT05487469: Thymosin α1 Use in Rheumatic Heart Disease Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass |
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| Recruiting | N/A | 200 | RoW | Thymosin Alpha1, Blank Control | Nanjing Medical University | Rheumatic Heart Disease, Cardiopulmonary Bypass, Immunotherapy | 12/23 | 12/23 | | |
Panda II, NCT05339529: Protective Effect of Thymosin Α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA II) |
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| Recruiting | N/A | 330 | RoW | Thymosin Alpha1, 28A-Glycine-28B-L-Arginine-28C-L-Glutamic Acid-28D-L-Alanine-28E-L-Proline-28F-L-Alanine-28G-L-Asparagine-, Blank control | Nanjing Medical University, Beijing Anzhen Hospital, Second Affiliated Hospital of Nanchang University, Qilu Hospital of Shandong University, The First Affiliated Hospital of Guangzhou Medical University, Northern Jiangsu People's Hospital, Guangdong Provincial People's Hospital, First Affiliated Hospital of Kunming Medical University, Nanjing First Hospital, Nanjing Medical University, Shanghai East Hospital,Tongji University School of Medicine, The Seventh Affiliated Hospital of Xinjiang Medical University, Teda International Cardiovascular Hospital, Tianjin, China, First Affiliated Hospital Bengbu Medical College, West China Hospital Affiliated with Sichuan University | Acute Aortic Syndrome, Aortic Dissection Type a | 12/25 | 12/25 | | |
NCT05782881: High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program |
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| Recruiting | N/A | 16000 | RoW | phone calls and encouraging patients' lifestyle change and medication adherence, Statin, Angiotensin-converting enzyme inhibitor, Angiotensin receptor neprilysin inhibitor, Glucagon-like peptide-1, Sodium-dependent glucose transporters 2 | Wuhan Union Hospital, China, Peking University First Hospital | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Coronary Disease | 12/23 | 12/24 | | |
NCT05881655: Slow Myopia Progression With Different Irradiance Light |
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| Recruiting | N/A | 75 | RoW | Airdoc Red Lighting Device, Repeated Red Light, Low Lever Laser Therapy, Low Intensity Light Therapy, Photobiomodulation Therapy, Seconee, 650nm Red Light, Special Spectacles to Control Myopia, Essilor® Stellest™ Lenses, H.A.L.T lens | Beijing Airdoc Technology Co., Ltd., Shanghai Children's Medical Center | Myopia, Progressive | 05/24 | 12/25 | | |
PANDA VI, NCT06195267: Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery |
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| Recruiting | N/A | 500 | RoW | Sivelestat, Blank control | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University, Beijing Anzhen Hospital | Aortic Dissection, Systemic Inflammatory Response Syndrome, Cardiovascular Diseases (CVD) | 12/25 | 12/25 | | |
COSEFDIP, NCT05755659: Clinical on the Safety and Efficacy of Fosaprepitant Dimeglumine for Injection in the Prevention of CINV. |
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| Recruiting | N/A | 3000 | RoW | Fosaprepitant Dimeglumine for Injection, ShanQi®️ | Xijing Hospital | Neoplasms | 10/24 | 12/24 | | |
PANDA, NCT06707350: Protective Effect of RIPC Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery (Panda VII) |
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| Not yet recruiting | N/A | 500 | RoW | Remote ischemic preconditioning (RIPC), sham condition (control group) | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University | Cardiopulmonary Bypass, Cardiovascular Diseases, Inflammatory Response During Cardiac Surgery | 12/25 | 12/25 | | |
NCT04837222: A Study of Brentuximab Vedotin in Adults With CD30-positive Lymphoma |
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| Active, not recruiting | N/A | 1000 | RoW | No Intervention | Takeda | Lymphoma | 06/26 | 06/26 | | |
NCT06723366: Protective Effect of Angong Niuhuang Against Negative Inflammatory Response and Neurologic Dysfunction After Cardiovascular Surgery |
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| Not yet recruiting | N/A | 120 | RoW | Angong Niuhuang Pill (ANP), Control (Standard treatment) | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University, Beijing Anzhen Hospital, Capital Medicine University | Cardio-pulmonary Bypass, Cardiovascular Surgery, Cerebral Protection, Brain Injury | 12/25 | 12/25 | | |
PANDA, NCT06730802: Protective Effect of PCSK9 Inhibitor Against Negative Inflammatory Response and Organ Dysfunction After Coronary Artery Bypass Grafting ( VIII) |
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| Not yet recruiting | N/A | 400 | RoW | PCSK9 inhibitor, Statin | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University, Beijing Anzhen Hospital | Myocardial Ischaemic Syndrome, Coronary Heart Disease | 12/26 | 12/26 | | |
NCT01932411: Factors Affect Outcomes in Cardiovascular Surgery |
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| Recruiting | N/A | 5000 | US | | University of California, Davis | Coronary Artery Disease, Valvular Diseases, Vascular Diseases | 02/25 | 07/25 | | |
| Recruiting | N/A | 2000 | RoW | Renal replacement therapy | Nanjing Medical University | Acute Kidney Injury, Cardiac Surgery | 12/25 | 12/25 | | |
NCT04398992: Additive Anti-inflammatory Action for Aortopathy & Arteriopathy |
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| Enrolling by invitation | N/A | 10000 | RoW | observation | Nanjing Medical University, Beijing Anzhen Hospital | Acute Aortic Syndrome | 12/40 | 12/40 | | |
| Recruiting | N/A | 500 | RoW | soluble ST2 | Nanjing Medical University | Cardiovascular Disease | 12/25 | 12/25 | | |
PANDA IV, NCT04444362: Protective Effect of Probacine Against Negative Gut Metabolism and Organ Dysfunction After Cardiovascular Surgery |
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| Enrolling by invitation | N/A | 500 | RoW | Intestinal Microbiota Transplant (IMT) Capsules | Nanjing Medical University, Beijing Anzhen Hospital, Shanghai East Hospital of Tongji University, West China Hospital, The First Affiliated Hospital of Guangzhou Medical University | Cardiovascular Disease, Cardiopulmonary Bypass | 12/25 | 12/25 | | |
PANDA, NCT06728605: Protective Effect of EECP Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery |
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| Not yet recruiting | N/A | 400 | RoW | Enhanced External Counterpulsation (EECP), Sham Comparator | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University | Coronary Heart Disease (CHD), Cardio-pulmonary Bypass, Congestive Heart Failure Chronic, Cardiogenic Shock Acute | 12/25 | 12/25 | | |
BEST-BAO, NCT05631847: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke |
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| Recruiting | N/A | 336 | RoW | Endovascular treatment, Intravenous thrombolysis (Alteplase) | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion, Thrombosis, Alteplase, Endovascular Treatment | 01/27 | 05/27 | | |
| Recruiting | N/A | 10000 | RoW | NIS | Second Affiliated Hospital, School of Medicine, Zhejiang University | Psoriasis | 07/30 | 07/30 | | |
NCT05454397: A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients |
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| Recruiting | N/A | 2000 | RoW | Observational study, no intervention | Nanfang Hospital of Southern Medical University, First Affiliated Hospital of Fujian Medical University, Yantai Yuhuangding Hospital, The First Hospital of Jilin University, Qilu Hospital of Shandong University, ZHEJIANG PROVINCE XIAOSHAN HOSPITAL, The First People's Hospital of Wenling, Ganzhou People's Hospital, Affiliated Hospital of Jining Medical hospital, Henan Provincial People's Hospital, Zhongda Hospital Southeast University, The Second Affiliated Hospital of Harbin Medical University, The First people's Hospital of Kunshan, The 2nd Affiliated Hospital of Wenzhou Medical University, THE FIRST PEOPLE'S HOSPITAL OF JIASHAN, The First Affiliated Hospital of Xi'an Jiaotong University Medical College, Fujian Province Zhangzhou Hospital, People's Hospital of Chongqing, Nanjing Zijin Hospital, Hangzhou Red Cross Hospital, Wenzhou Hospital of Chinese Medicine, Kaifeng Central Hospital, First Affiliated Hospital of Guangxi Medical University, Zhongshan Hospital of Xiamen University, Xi'an Encephalopathy of Traditional Chinese Medicine Hospital, 903 Hospital of the Chinese People's Liberation Army Joint Logistics and Security Forces, Xiangya Hospital of Central South University, Second Affiliated Hospital of Suzhou University, Tongji Hospital, The Affiliated Hospital o fQingdao University, The First Affiliated Hospital of Anhui Medical University, Yancheng Third People's Hospital, Linyi People's Hospital, Dongfang Hospital of Beijing University of Chinese Medicine, Affiliated Hospital of Qingdao University | Acute Stroke | 10/22 | 10/23 | | |
NCT04970264: A Multicenter, Open and Observational Real World Study on the Prognosis and Treatment in Young Women With Breast Cancer |
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| Recruiting | N/A | 2000 | RoW | | Tianjin Medical University Cancer Institute and Hospital | Breast Cancer | 03/23 | 03/25 | | |
| Recruiting | N/A | 300 | RoW | ECMO | Nanjing Medical University | Cardiogenic Shock, Cardiac Arrest, Heart Failure, Acute Respiratory Failure, Acute Respiratory Distress Syndrome | 12/25 | 12/25 | | |
| Recruiting | N/A | 1000 | RoW | Intra Aortic Balloon Pump | Nanjing Medical University | Acute Coronary Syndrome, Cardiogenic Shock, Coronary Artery Disease, Heart Failure, Left Ventricular Dysfunction, Low Cardiac Output Syndrome, Post-cardiac Surgery | 12/25 | 12/25 | | |
| Zhang, Lin |
KEYSTONE-002, NCT04807673: Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC |
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| Recruiting | 3 | 342 | RoW | Pembrolizumab, Keytruda, Paclitaxel, Cisplatin, neoadjuvant chemoradiotherapy | Tianjin Medical University Cancer Institute and Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Shanghai Chest Hospital, Ruijin Hospital, Hebei Medical University Fourth Hospital, Harbin Medical University, Liaoning Tumor Hospital & Institute, Shanxi Province Cancer Hospital, Shandong Jining No.1 People's Hospital, Weifang People's Hospital, Tianjin Medical University General Hospital, Shandong Provincial Hospital | Esophageal Squamous Cell Carcinoma | 12/23 | 05/28 | | |
PRACTICE, NCT06794684: PRogression of Atheroma Evaluated by CT Angiography and IntraCoronary Imaging tEchniques |
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| Recruiting | N/A | 50000 | RoW | | Ruijin Hospital | Coronary Arterial Disease (CAD), Coronary Arteriosclerosis | 05/27 | 05/30 | | |
Pan-CHESS1801, NCT03778775: Transient Elastography (FibroTouch) for Assessing Risk of Gastroesophageal Varices Bleeding in Compensated Cirrhosis |
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| Recruiting | N/A | 200 | Japan, RoW | Liver sitffness measurement, Esophagogastroduodenoscopy | Nanfang Hospital of Southern Medical University, Beijing Tsinghua Changgeng Hospital, LanZhou University, Beijing 302 Hospital, Xijing Hospital of Digestive Diseases, Wuhan Union Hospital, China, Zhujiang Hospital, Second Affiliated Hospital of Xi'an Jiaotong University, The Central Hospital of Lishui City, Xingtai People's Hospital, Seventh Medical Center of PLA Army General Hospital, Shandong Provincial Hospital, Shunde Hospital, Southern Medical University, Medistra Hospital, University of Indonesia, Ankara University, Osaka City University, Chulalongkorn University | Compensated Liver Cirrhosis, Gastroesophageal Varices Bleeding | 06/21 | 03/22 | | |
NCT04858750: Comparison and Evaluation of USSQ, OABSS, and the Drainage/Anti-reflux Effect Between Three Kinds of Ureteral D-J Stents in Patients Who Underwent URL |
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| Recruiting | N/A | 150 | RoW | Placement of ureteral D-J stent after ureteroscopic holmium laser lithotripsy | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Urolithiasis, Overactive Bladder Syndrome | 04/23 | 05/23 | | |
| Recruiting | N/A | 400 | RoW | Goal-directed EN therapy, Conventional EN therapy | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Esophagus Cancer | 08/26 | 05/31 | | |
CSILS, NCT04527861: Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer |
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| Recruiting | N/A | 710 | RoW | Single-incision Laparoscopic Surgery, SILS, Conventional Laparoscopic Surgery, CLS | Ruijin Hospital, Dongfang Hospital Affiliated to Tongji University, Fudan University, Changhai Hospital, Shengjing Hospital, RenJi Hospital, Liaoning Cancer Hospital & Institute, Zhejiang Provincial People's Hospital, Shandong Provincial Hospital, The General Hospital of Western Theater Command, Shanghai Jiao Tong University School of Medicine | Colorectal Cancer, Colon Cancer, Rectal Cancer | 04/24 | 04/29 | | |
NCT05352074: STOPS Trial: Total vs Subtotal Colectomy for Slow Transit Constipation |
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| Recruiting | N/A | 202 | RoW | subtotal colectomy with cecal-rectal anastomosis, total colectomy with ileorectal anastomosis | Third Military Medical University | Slow Transit Constipation, Surgery | 12/24 | 12/26 | | |
| Albertson, Timothy |
NCT05354141: Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS) |
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| Recruiting | 3 | 970 | US | ExoFlo, Intravenous normal saline | Direct Biologics, LLC | Acute Respiratory Distress Syndrome, ARDS | 03/25 | 08/25 | | |
| Recruiting | 2 | 1500 | US | Remdesivir, GS-5734, Imatinib Mesylate, Dexamethasone, Cenicriviroc, Icatibant, Firazyr, Apremilast, Otezla, dornase alfa, Pulmozyme, Celecoxib, celebrex, Famotidine, Pepcid, IC14, Aviptadil, Zyesami, narsoplimab, OMS721, Cyproheptadine, periactin, Cyclosporine, CsA | QuantumLeap Healthcare Collaborative, University of California, San Francisco, University of Pennsylvania, Emory University, University of Alabama at Birmingham, University of Colorado, Denver, University of Southern California, Yale University, Wake Forest University Health Sciences, Sanford Health, Long Beach Memorial Medical Center, Georgetown University, University of California, Davis, Hoag Memorial Hospital Presbyterian, Main Line Health, DHR Health Institute for Research and Development, University of California, Irvine, Corewell Health, Kaiser Permanente, University of Michigan, West Virginia University, University of Miami, University Hospitals Cleveland Medical Center, Virtua Health, M.D. Anderson Cancer Center | COVID-19 | 07/28 | 07/30 | | |
| Recruiting | 2 | 66 | Europe, US | Reparixin 600mg, REP, Matching Placebo, Control | Dompé Farmaceutici S.p.A, Dompè farmaceutici s.p.a. | Acute Respiratory Distress Syndrome, Adult | 08/25 | 08/25 | | |
| Bewley, Arnauld |
NCT03849898: Patients 60 Years and Older Suffering From Mandibular Fractures Registry |
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| Terminated | N/A | 25 | Europe, US, RoW | Surgery, Operative, Non-Surgical fracture treatment | AO Clinical Investigation and Publishing Documentation | Mandibular Fractures | 03/23 | 03/23 | | |
| Sandberg, Sarah |
ASPIRE, NCT06588686: A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic Pulmonary Fibrosis. |
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| Recruiting | 2 | 270 | Europe, Canada, US, RoW | Buloxibutid, C21, Placebo | Vicore Pharma AB, Population Services International | Idiopathic Pulmonary Fibrosis (IPF) | 02/27 | 03/27 | | |
| Borbe, Abigail Higareda |
NCT05358886: A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome |
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| Recruiting | 3 | 150 | US | BPN14770/ zatolmilast, Placebo | Tetra Discovery Partners | Fragile X Syndrome | 06/25 | 09/25 | | |
NCT05163808: A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome |
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| Recruiting | 2/3 | 150 | US | zatolmilast, BPN14770, Placebo | Tetra Discovery Partners | Fragile X Syndrome | 09/25 | 12/25 | | |
| Feldman, Gary |
NCT05358886: A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome |
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| Recruiting | 3 | 150 | US | BPN14770/ zatolmilast, Placebo | Tetra Discovery Partners | Fragile X Syndrome | 06/25 | 09/25 | | |
| Recruiting | 3 | 250 | Europe, US, RoW | ZYN002 - transdermal gel, cannabidiol formulated as a clear gel that can be applied to the skin (transdermal delivery), Placebo, Placebo Comparator, Matching Placebo | Zynerba Pharmaceuticals, Inc., Zynerba Pharmaceuticals, Inc. | Fragile X Syndrome | 05/25 | 05/25 | | |
| Active, not recruiting | 3 | 196 | Europe, Canada, US, RoW | Ecopipam Hydrochloride | Emalex Biosciences Inc. | Tourette Disorder | 12/24 | 12/24 | | |
NCT05163808: A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome |
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| Recruiting | 2/3 | 150 | US | zatolmilast, BPN14770, Placebo | Tetra Discovery Partners | Fragile X Syndrome | 09/25 | 12/25 | | |
| Lupercio |
ASPIRE, NCT06588686: A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic Pulmonary Fibrosis. |
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| Recruiting | 2 | 270 | Europe, Canada, US, RoW | Buloxibutid, C21, Placebo | Vicore Pharma AB, Population Services International | Idiopathic Pulmonary Fibrosis (IPF) | 02/27 | 03/27 | | |
| Bustos, Ulises |
NCT05358886: A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome |
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| Recruiting | 3 | 150 | US | BPN14770/ zatolmilast, Placebo | Tetra Discovery Partners | Fragile X Syndrome | 06/25 | 09/25 | | |
NCT05163808: A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome |
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| Recruiting | 2/3 | 150 | US | zatolmilast, BPN14770, Placebo | Tetra Discovery Partners | Fragile X Syndrome | 09/25 | 12/25 | | |
