University of Colorado Denver
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 416 Trials 
1315 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Schwartz, David
NRG-LU008, NCT05624996: Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-small Cell Lung Cancer

Recruiting
3
474
US
Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized Tomography, CT, CT Scan, tomography, Durvalumab, Imfinzi, Immunoglobulin G1, Anti-(Human Protein B7-H1) (Human Monoclonal MEDI4736 Heavy Chain), Disulfide with Human Monoclonal MEDI4736 Kappa-chain, Dimer, MEDI-4736, MEDI4736, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16, VP 16-213, VP-16, VP-16-213, VP16, Image Guided Radiation Therapy, IGRT, image-guided radiation therapy, Image-Guided Radiotherapy, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Pemetrexed, MTA, Multitargeted Antifolate, Pemfexy, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Body Radiation Therapy, SABR, SBRT, Stereotactic Ablative Body Radiation Therapy
NRG Oncology, National Cancer Institute (NCI)
Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8
10/31
10/36
RTOG 1216, NCT01810913: Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Recruiting
2/3
613
Canada, US, RoW
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG 7446, RG-7446, RG7446, RO 5541267, RO-5541267, RO5541267, Tecentriq, Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cetuximab, C 225, C-225, C225, Cetuximab Biosimilar CDP-1, Cetuximab Biosimilar CMAB009, Cetuximab Biosimilar KL 140, Chimeric Anti-EGFR Monoclonal Antibody, Chimeric MoAb C225, Chimeric Monoclonal Antibody C225, Erbitux, IMC-C225, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Docetaxel, Docecad, RP 56976, RP-56976, RP56976, Taxotere, Taxotere Injection Concentrate, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Laboratory Biomarker Analysis, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Quality-of-Life Assessment, Quality of Life Assessment
National Cancer Institute (NCI), NRG Oncology
Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7, Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7
01/27
01/27
NCT03478553: The Genetics of Pulmonary Fibrosis

Recruiting
N/A
1000
US
Blood draw, Questionnaire
University of Colorado, Denver, United States Department of Defense, University of Alabama at Birmingham, National Jewish Health, University of California, San Francisco, University of Pittsburgh, Baylor University
Idiopathic Pulmonary Fibrosis (IPF)
12/26
12/26
APPLe, NCT04564183: Advancing Prevention of Pulmonary Fibrosis

Active, not recruiting
N/A
800
US
Sample collection, Questionnaires, High resolution CT scan of the chest, Pulmonary Function Test
University of Colorado, Denver, Mayo Clinic, University of California, Los Angeles, University of Texas, University of Pennsylvania
IPF, Pulmonary Fibrosis, ILD
10/24
08/26
GWAS, NCT01088217: Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)

Recruiting
N/A
8000
US, RoW
National Jewish Health, University of Colorado, Denver, Vanderbilt University, Landspitali University Hospital
Idiopathic Pulmonary Fibrosis, Familial Pulmonary Fibrosis, Idiopathic Interstitial Pneumonia, Familial Interstitial Pneumonia
06/25
06/25
Carlo, Waldemar A
NCT06518603: Caffeine Citrate in Preterm Infants At Risk of Apnea in Zambia

Not yet recruiting
4
340
RoW
Caffeine citrate 20mg/kg/day, Placebo-Sterile water 1ml/kg/day
University of Alabama at Birmingham, University Teaching Hospital, Lusaka, Zambia, Centre for Infectious Disease Research in Zambia
Premature Infant Disease, Apnea of Prematurity, Development, Infant
12/25
11/26
NCT01702805: Transfusion of Prematures Trial

Active, not recruiting
3
1824
US
Liberal Cell Transfusion, Restricted red cell transfusion
NICHD Neonatal Research Network, National Heart, Lung, and Blood Institute (NHLBI), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant, Newborn, Diseases, Infant, Extremely Low Birth Weight, Infant, Small for Gestational Age, Bronchopulmonary Dysplasia (BPD), Anemia
01/20
08/25
NCT01353313: Hydrocortisone for BPD

Active, not recruiting
3
800
US
Hydrocortisone, Placebo
NICHD Neonatal Research Network, National Center for Research Resources (NCRR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Heart, Lung, and Blood Institute (NHLBI), National Center for Advancing Translational Sciences (NCATS)
Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature, Bronchopulmonary Dysplasia
09/20
01/25
MoCHA, NCT03340727: Moderately Preterm Infants With Caffeine at Home for Apnea () Trial

Terminated
3
827
US
Caffeine Citrate, Placebo
NICHD Neonatal Research Network, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Apnea of Prematurity
01/23
03/23
NCT04214834: Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

Active, not recruiting
3
190
US
Morphine, Methadone
Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Neonatal Opioid Withdrawal Syndrome
01/24
06/26
MIDAS, NCT06679855: Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

Not yet recruiting
3
316
US
Milrinone infusion, Placebo infusion
NICHD Neonatal Research Network, National Heart, Lung, and Blood Institute (NHLBI)
Post-ligation Cardiac Syndrome
06/27
08/29
BiB, NCT04545866: The Budesonide in Babies () Trial

Active, not recruiting
3
1160
US
budesonide (Pulmicort nebulizing suspension)., Pulmicort nebulizing suspension., surfactant (poractant alfa;Curosurf), poractant alfa;Curosurf
NICHD Neonatal Research Network, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bronchopulmonary Dysplasia (BPD), Respiratory Distress Syndrome, Prematurity; Extreme, Neonatal
09/24
12/26
NCT03456336: Management of the PDA Trial

Active, not recruiting
3
836
US
Active Treatment, Expectant Management
NICHD Neonatal Research Network, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant, Premature, Patent Ductus Arteriosus, Infant, Newborn, Diseases, Patent Ductus Arteriosus After Premature Birth
04/25
05/27
MIDAS, NCT03231735: Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome

Completed
2/3
60
US
Mid frequency ventilation, Standard frequency ventilation
University of Alabama at Birmingham, University of South Alabama
Ventilator-Induced Lung Injury, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia, Preterm Infant
11/21
10/24
NCT03779711: Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome

Active, not recruiting
2b
95
US
Autologous (self) mononuclear cells derived from umbilical cord blood, Stage II Surgical repair
Timothy J Nelson, MD, PhD, University of Oklahoma, Children's Hospital of Philadelphia, Children's Hospital Los Angeles, Children's Hospital Colorado, Children's Hospitals and Clinics of Minnesota, Ochsner Health System, Children's of Alabama, Children's Hospital Medical Center, Cincinnati
Hypoplastic Left Heart Syndrome
05/22
02/26
NCT02951130: Milrinone in Congenital Diaphragmatic Hernia

Active, not recruiting
2
66
US
Milrinone, Milrinone Lactate Injection, Primacor, Placebo (5% Dextrose), D5W
NICHD Neonatal Research Network, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Congenital Diaphragmatic Hernia, Persistent Pulmonary Hypertension of the Newborn, Hypoxemic Respiratory Failure, Pulmonary Hypoplasia
09/24
03/25
PRISM, NCT06377098: Intrapartum Sildenafil in Laboring Mothers

Not yet recruiting
2
1000
RoW
Sildenafil 50 mg Oral Tablet, Revatio, Sildenafil, Placebo Oral Tablet
University of Alabama at Birmingham, University Teaching Hospital, Lusaka, Zambia, Egerton University, Cameroon Baptist Convention Health
Neonatal Asphyxia, Intrapartum Fetal Distress, Development, Infant, Intrapartum Asphyxia
08/26
09/28
NCT06522854: Oral Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings

Not yet recruiting
2
2000
RoW
Sildenafil 50 mg Oral Tablet, Revatio, Placebo Oral Tablet
University of Alabama at Birmingham, University of Lagos, Nigeria, Ladoke Akintola University of Technology Teaching Hospital, Ogbomoso, Lagos State University, National Health and Medical Research Council, Australia, Mater Medical Research Institute, The University of Queensland
Intrapartum Fetal Distress, Neonatal Asphyxia, Intrapartum Asphyxia, Instrumental Delivery; Affecting Fetus
05/26
11/26
NCT04907526: Intramyocardial Injection of Autologous UCB-MNC During Fontan Surgery for SRV Dependent CHD

Active, not recruiting
1
30
US
Autologous mononuclear cells
Timothy J Nelson, MD, PhD, Mayo Clinic, University of Oklahoma, Children's Hospital of Philadelphia, Children's Hospital Los Angeles, Children's Hospitals and Clinics of Minnesota, Children's Hospital Colorado, Ochsner Health System, Children's of Alabama, Children's Hospital Medical Center, Cincinnati, The Hospital for Sick Children
Congenital Heart Disease, SRV Dependent
05/23
06/25
NCT05403684: Impact of Hindmilk on Weight Gain Among Moderate to Very Preterm Infants in Zambia

Completed
N/A
214
RoW
High-volume breastmilk
University of Alabama at Birmingham, Centre for Infectious Disease Research in Zambia, Chiesi Foundation
Postnatal Growth Restriction
12/22
02/23
COCO, NCT04792099: CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial

Completed
N/A
38
US
Continuous positive airway pressure, CPAP, Nasal Cannula, NC
University of Alabama at Birmingham
Infant, Newborn, Disease, Hypoxia, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
03/23
03/23
MNH, NCT01073475: Maternal Newborn Health Registry

Recruiting
N/A
950000
US, RoW
There is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
NICHD Global Network for Women's and Children's Health
Pregnancy Outcome Trends in Low-resource Geographic Areas
01/25
01/25
NCT01604317: Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part I

Active, not recruiting
N/A
182
RoW
Resuscitation-torso plastic bag, Resuscitation-partial-head plastic bag
University of Alabama at Birmingham, Children's Health System, Alabama
Hypothermia, Immature Newborn
08/25
08/25
IMPACT, NCT06335524: Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants

Recruiting
N/A
188
US
Finger puppet, Bookworm reading intervention training and routine EDI care.
University of Alabama at Birmingham
Child Development, Infant Development, Infant, Premature, Diseases
08/26
08/28
NCT03927833: Cycled Phototherapy

Recruiting
N/A
1700
US
Phototherapy lights
NICHD Neonatal Research Network, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hyper Bilirubinemia, Premature Infant
07/25
07/25
NPC-QIC, NCT02852031: National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

Recruiting
N/A
1000
Europe, Canada, US
Collaborative Learning Network
Children's Hospital Medical Center, Cincinnati
Hypoplastic Left Heart Syndrome (HLHS)
05/26
05/28
NCT00063063: Generic Database of Very Low Birth Weight Infants

Recruiting
N/A
80000
US
NICHD Neonatal Research Network, National Center for Research Resources (NCRR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
03/30
03/30
NCT00009633: Follow-up Visit of High Risk Infants

Recruiting
N/A
68000
US
NICHD Neonatal Research Network, National Center for Research Resources (NCRR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
03/30
03/30
Dabelea, Dana
DPPOS, NCT00038727: Diabetes Prevention Program Outcomes Study

Active, not recruiting
3
2779
US
DPPOS Group Lifestyle, Metformin, Glucophage, DPPOS Boost Lifestyle, Intensive Lifestyle Group Session, Intensive lifestyle session (ILS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Aging (NIA), National Institute on Minority Health and Health Disparities (NIMHD), National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI), National Eye Institute (NEI), National Center for Research Resources (NCRR), Office of Research on Women's Health (ORWH), Centers for Disease Control and Prevention, American Diabetes Association, Indian Health Service, General Clinical Research Program, US Department of Veterans Affairs
Diabetes Mellitus, Cancer, CVD
10/24
01/25
NCT06160037: Influence of Prenatal and Early Childhood Home-Visiting by Nurses on Development of Chronic Disease

Recruiting
N/A
742
US
Transportation and Developmental Screening, Transportation, Screening, and Nurse-Visitation during Pregnancy and Infancy
University of Colorado, Denver, University of Rochester, Medpace, Inc.
Chronic Disease
04/24
04/24
NCT02273297: Healthy Start: Exploring the Fuel-mediated Programming of Neonatal Growth

Recruiting
N/A
2821
US
Maternal factors
University of Colorado, Denver, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Center for Advancing Translational Sciences (NCATS)
Pregnancy, Obesity
07/26
07/26
Messersmith, Wells
NCT03781154: Predictors of Physical Activity Maintenance in Colorectal Cancer Survivors

Completed
3
31
US
Group Exercise
University of Colorado, Denver, American Cancer Society, Inc., Colorado State University
Colorectal Cancer
06/23
06/23
AGICC, NCT02723331: Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates

Active, not recruiting
2
48
US
Nab paclitaxel, Abraxane, Gemcitabine, Gemzar
Academic Thoracic Oncology Medical Investigators Consortium, Celgene Corporation, Criterium, Inc., University of Colorado, Denver
Pancreatic Cancer, Pancreatic Adenocarcinoma, Pancreas Ductal Adenocarcinoma
12/22
05/25
C-800-25, NCT05608044: A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Active, not recruiting
2
234
Europe, US, RoW
Botensilimab, AGEN1181, Balstilimab, AGEN2034, Standard of Care
Agenus Inc.
Metastatic Colorectal Cancer
02/25
07/25
NCT05167409: A Study of Evorpacept (ALX148) With Cetuximab and Pembrolizumab for Refractory Microsatellite Stable Metastatic Colorectal Cancer

Active, not recruiting
2
48
US
Evorpacept (ALX148), evorpacept, Cetuximab, Erbitux, Pembrolizumab, Keytruda
University of Colorado, Denver, ALX Oncology Inc., Merck Sharp & Dohme LLC, Eli Lilly and Company, Criterium, Inc., Academic GI Cancer Consortium (AGICC)
Microsatellite Stable Metastatic Colorectal Cancer
12/25
03/26
NCT02521844: A Study to Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours

Active, not recruiting
1
89
US, RoW
ETC-1922159, Pembrolizumab
EDDC (Experimental Drug Development Centre), A*STAR Research Entities, PPD DEVELOPMENT, LP
Solid Tumors
10/24
10/24
NX-1607-101, NCT05107674: A Study of NX-1607 in Adults With Advanced Malignancies

Recruiting
1
345
Europe, US
NX-1607, Cbl-b Inhibitor, Paclitaxel
Nurix Therapeutics, Inc.
Ovarian Cancer, Epithelial, Gastric Cancer, GastroEsophageal Junction (GEJ) Cancer, Head and Neck Squamous Cell Carcinoma, Metastatic or Unresectable Melanoma, Non-small Cell Lung Cancer (NSCLC), Metastatic Castration-resistant Prostate Cancer (mCRPC), Malignant Pleural Mesothelioma (MPM), Triple Negative Breast Cancer (TNBC), Metastatic Urothelial Carcinoma, Cervical Cancer, Diffuse Large B Cell Lymphoma (DLBCL), Richter Transformation, Microsatellite Stable Colorectal Carcinoma
08/26
02/28
NCT02955446: Compassionate Use Protocol for PF-03084014 in Patients With Advanced Solid Tumor Malignancies

No Longer Available
N/A
US
PF-03084014, Gamma Secretase Inhibitor
University of Colorado, Denver, SpringWorks Therapeutics, Inc.
Neoplasm, Desmoid Tumor
 
 
Berman, Brian
NCT06771323: Safety and Effectiveness of Valbenazine as Adjunct Therapy to Botulinum Toxin Injections in Cervical Dystonia

Not yet recruiting
2
20
US
Valbenazine, Placebo
Virginia Commonwealth University, Neurocrine Biosciences
Cervical Dystonia
01/26
01/26
NCT05157763: A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma

Recruiting
1/2
32
US
EscharEx 5% (EX-02 formulation), EX-02 5%
MediWound Ltd
Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
05/22
06/22
CNXR-001D, NCT05279495: Double-Blind Study Determining the Efficacy of CannaXR in Decreasing UVA Premutagenic and Photoaging Markers

Completed
N/A
20
US
In a double-blinded fashion, 250 mg CANNAXR cream, TOPICAL CBD CANNAXR Cream, Topical VEHICLE cream
MINO Labs, LLC
Photoaging
04/23
05/23
Hill, James
IWCR, NCT04907396: International Weight Control Registry

Recruiting
N/A
100000
US
Tufts University, University of Alabama at Birmingham, University of Colorado, Denver, University of Kansas Medical Center, Pennington Biomedical Research Center, University of New Hampshire, United States Military Academy, West Point
Weight Loss, Overweight, Obesity
12/25
12/25
NPC-QIC, NCT02852031: National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

Recruiting
N/A
1000
Europe, Canada, US
Collaborative Learning Network
Children's Hospital Medical Center, Cincinnati
Hypoplastic Left Heart Syndrome (HLHS)
05/26
05/28
NCT05701657: Nutrition for Precision Health, Powered by the All of Us

Recruiting
N/A
8000
US
Diet A, Diet B, Diet C, Liquid Mixed Meal Tolerance Test, LMMTT, Diet-Specific Mixed Meal Tolerance Test, Diet-Specific MMTT
RTI International, National Institutes of Health (NIH), University of North Carolina, Chapel Hill, Northwestern University, Illinois Institute of Technology, University of Chicago, Pennington Biomedical Research Center, Louisiana State University Health Sciences Center in New Orleans, University of California, Davis, University of California, Los Angeles, Cedars-Sinai Medical Center, University of Alabama at Birmingham, Tufts University, Massachusetts General Hospital, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Center for Advancing Translational Sciences (NCATS), National Cancer Institute (NCI), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), City University of New York, School of Public Health, Mayo Clinic, University of California, San Diego, University of Hawaii, Vanderbilt University Medical Center, National Heart, Lung, and Blood Institute (NHLBI), National Center for Complementary and Integrative Health (NCCIH), National Institute of Drug Abuse, Public Health Informatics Computational and Operations Research, University of Southern California, Cornell University, University of Alabama, Tuscaloosa, North Carolina State University, University of North Carolina, Charlotte, Duke University, Stevens Institute of Technology, Purdue University, United States Military Academy at West Point, USDA, Western Human Nutrition Research Center, North Carolina Central University, Wake Forest University Health Sciences, Boston University, Children's Hospital of Richmond, Virginia Commonwealth University, Verily Life Sciences LLC, Indiana University, Fred Hutchinson Cancer Center, Columbia University, University of Pennsylvania
Nutrition, Health, Dietary Habits
12/26
01/27
NCT06082453: Modernizing Perinatal Syphilis Testing

Recruiting
N/A
924
US
Quantitative polymerase chain reaction (qPCR) assay for detection of Treponema pallidum, Aptima Treponema pallidum transcription-mediated amplification (TMA) assay for detection of Treponema pallidum, Center for Disease Control (CDC) Sexually Transmitted Infections (STI) 2021 Treatment Guidelines for diagnosis of syphilis
The University of Texas Health Science Center, Houston, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Syphilis
11/27
11/27
NCT05685745: Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

Recruiting
N/A
5000
Europe, Canada, Japan, US
The University of Texas Health Science Center, Houston, Nationwide Children's Hospital, University of Iowa, University of Alabama at Birmingham, Jichi Medical University, Saitama Medical University
Infant, Extremely Premature, Obstetric Labor, Premature, Premature Birth, Intensive Care, Neonatal, Intensive Care Units, Neonatal
01/28
01/28
Campbell, Thomas B
INSITE-DME, NCT05610319: Treat & Extend Versus Fixed Dosing with Faricimab for Management of Diabetic Macular Edema: a Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial

Active, not recruiting
4
446
Europe, Canada, US, RoW
Faricimab
McMaster University, Hoffmann-La Roche
Diabetic Macular Edema
12/26
12/26
NCT04636437: Doravirine for Persons With Excessive Weight Gain on Integrase Inhibitors and Tenofovir Alafenamide

Active, not recruiting
4
222
US
Doravirine 100 Mg, Tenofovir alafenamide/emtricitabine, tenofovir alafenamide/lamivudine, Integrase strand transfer inhibitors, tenofovir disproxil fumarate/emtricitabine, tenofovir disproxil fumarate/lamivudine
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
11/24
11/24
STOMP, NCT05534984: Study of Tecovirimat for Human Mpox Virus

Active, not recruiting
3
719
Japan, US, RoW
Tecovirimat Oral Capsule, Placebo, Tecovirimat Oral Capsule (Open Label)
National Institute of Allergy and Infectious Diseases (NIAID), SIGA Technologies
MPOX
10/24
09/25
PURGE-C, NCT04042740: Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection

Completed
2
45
US, RoW
Glecaprevir/Pibrentasvir (G/P), Mavyret
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, AbbVie, National Institute of Allergy and Infectious Diseases (NIAID)
Hepatitis C Infection, HIV Infection
05/23
08/23
NCT05414851: Low-Carbohydrate and Plant-Based Dietary Effects on Vascular Health

Completed
N/A
45
US
Whole-Food, Plant-Based Diet and Low-Carbohydrate Diet
University of Rochester
Heart Disease, Ischemic, Hyperlipidemias, Hypertension
04/24
04/24
Freedman, Robert
CHIPAHA, NCT00763828: Can Hypothermia be Incorporated Into Primary Angioplasty for Heart Attack?

Not yet recruiting
N/A
20
US
Life Recovery Systems ThermoSuit, Life Recovery Systems ThermoSuit(R) System
Life Recovery Systems
ST-Elevation Myocardial Infarction
02/25
05/25
Bull, Sheana
NCT03973931: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications

Active, not recruiting
N/A
9501
US
Nudge
University of Colorado, Denver, National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Adherence, Medication, Medication Adherence, Diabetes Mellitus, Hypertension, Hyperlipidemias, Coronary Artery Disease, Atrial Fibrillation
01/24
06/24
Creinin, Mitchell D
NCT04457076: Evaluation of the Efficacy, Safety, and Tolerability of LevoCept

Not yet recruiting
3
1525
US
LevoCept
Sebela Women's Health Inc., PRA Health Sciences
Contraception, Women at Risk for Pregnancy
01/29
01/31
NCT04143659: A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception

Recruiting
1
136
US
levonorgestrel butanoate (LB) injection
Health Decisions, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Healthy Women, Female Contraception
09/24
09/24
NCT06127199: Contraceptive Efficacy Study of Ovaprene

Recruiting
N/A
656
US
Ovaprene
Daré Bioscience, Inc., Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Contraception
06/25
09/25
Anderson, Peter
NCT05140954: The Women TAF-FTC Benchmark Study

Completed
2/3
54
RoW
co-formulated 25mg TAF/ 200mg FTC, Descovy
University of Washington, Kenya Medical Research Institute, University of Colorado, Denver, Gilead Sciences
HIV Infections
12/23
12/23
NCT06435026: Optimizing PrEP Regimens for Pregnant Women in Sub-Saharan Africa (O-PrEP Study) - Stage 1

Recruiting
2
54
RoW
FTC/TDF 200mg/300mg, PrEP, FTC/TDF 300mg/450mg, FTC/TDF 400mg/600mg
University of North Carolina, Chapel Hill, National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Prevention, Pregnancy
02/25
02/25
NCT05057858: The Women TDF-FTC Benchmark Study

Active, not recruiting
2
72
RoW
co-formulated 300 mg TDF/ 200mg FTC, Truvada
University of Washington, University of Colorado, Denver, Kenya Medical Research Institute, National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
01/25
01/25
Tracer Pilot, NCT04535934: Novel Approaches for Quantitative Assessment of Adherence

Completed
N/A
15
US
Adenine 5+ (five stable-labeled nitrogens), taggant
University of Colorado, Denver, National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
11/22
11/22
ACT, NCT05335590: Adherence and Clinical Correlates in Persons With HIV on TAF

Active, not recruiting
N/A
384
US
University of Colorado, Denver
Hiv
05/25
05/25
NCT04065347: Quantification of Tenofovir Alafenamide Adherence (QUANTI-TAF)

Completed
N/A
84
US
Digital Pill, etectRx ID-Cap System
University of Colorado, Denver, National Institute of Allergy and Infectious Diseases (NIAID)
HIV/AIDS, Adherence, Medication
05/23
05/23
HOME-1, NCT04979728: HIV Outpatient Monitoring Evaluation Through Self-collection of Dried Blood Spots

Recruiting
N/A
150
US
At Home Self-Collections, Tasso-M20, Tasso+, Mitra, DBS by fingerstick
University of Colorado, Denver, National Institute of Allergy and Infectious Diseases (NIAID)
HIV Treatment, HIV Prevention
12/25
12/25
Rice, Todd W
RSI, NCT05277896: Randomized Trial of Sedative Choice for Intubation

Recruiting
4
2364
US
Ketamine, Etomidate
Vanderbilt University Medical Center, National Heart, Lung, and Blood Institute (NHLBI), Patient-Centered Outcomes Research Institute
Acute Respiratory Failure
01/27
02/27
GRAIL^3, NCT04706507: Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

Active, not recruiting
3
500
US
IV Ganciclovir, Cytovene
Fred Hutchinson Cancer Center, National Heart, Lung, and Blood Institute (NHLBI)
Acute Respiratory Failure
10/24
08/27
NCT05571059: Oral Ifetroban in Patients with Idiopathic Pulmonary Fibrosis (IPF)

Recruiting
2
128
US
Ifetroban Sodium, ifetroban, Placebo
Cumberland Pharmaceuticals
Idiopathic Pulmonary Fibrosis
01/26
01/26
STRATEGIC, NCT05583539: Thromboelastography Guided Blood Product Transfusion for Upper Gastrointestinal Bleeding in Cirrhosis

Withdrawn
N/A
40
NA
Thromboelastography
Vanderbilt University Medical Center
Cirrhosis, Liver, Coagulopathy, GastroIntestinal Bleeding
06/25
06/25
Verneris, Michael R
NCT05457556: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Recruiting
3
435
Canada, US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspiration, Busulfan, 1, 4-Bis[methanesulfonoxy]butane, BUS, Busilvex, Bussulfam, Busulfanum, Busulfex, Busulphan, CB 2041, CB-2041, Glyzophrol, GT 41, GT-41, Joacamine, Methanesulfonic Acid Tetramethylene Ester, Methanesulfonic acid, tetramethylene ester, Mielucin, Misulban, Misulfan, Mitosan, Myeleukon, Myeloleukon, Myelosan, Mylecytan, Myleran, Sulfabutin, Tetramethylene Bis(methanesulfonate), Tetramethylene bis[methanesulfonate], WR-19508, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Asta B 518, B 518, B-518, B518, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamide Monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR 138719, WR- 138719, WR-138719, WR138719, Echocardiography, EC, Fludarabine, Fluradosa, Haploidentical Hematopoietic Cell Transplantation, Haploidentical Stem Cell Transplantation, HLA-Haploidentical Hematopoietic Cell Transplantation, Stem Cell Transplantation, Haploidentical, Lapine T-Lymphocyte Immune Globulin, Anti-Thymocyte Globulin Rabbit, Antithymocyte Globulin Rabbit, Antithymocyte globulin rabbit ATG, Grafalon, Imtix, Rabbit Anti-Human Thymocyte Globulin (RATG), Rabbit Anti-Thymocyte Globulin, Rabbit Antithymocyte Globulin, Rabbit ATG, Thymoglobulin, Lumbar Puncture, LP, Spinal Tap, Matched Unrelated Donor Hematopoietic Cell Transplantation, MUD-HCT, Melphalan, Alanine Nitrogen Mustard, CB-3025, L-PAM, L-Phenylalanine Mustard, L-Sarcolysin, L-Sarcolysin Phenylalanine mustard, L-Sarcolysine, Melphalan for Injection-Hepatic Delivery System, Melphalanum, Phenylalanine Mustard, Phenylalanine Nitrogen Mustard, Sarcoclorin, Sarkolysin, WR-19813, Methotrexate, Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, CL 14377, CL-14377, Emtexate, Emthexat, Emthexate, Farmitrexat, Fauldexato, Folex, Folex PFS, Lantarel, Ledertrexate, Lumexon, Maxtrex, Medsatrexate, Metex, Methoblastin, Methotrexate LPF, Methotrexate Methylaminopterin, Methotrexatum, Metotrexato, Metrotex, Mexate, Mexate-AQ, MTX, Novatrex, Rheumatrex, Texate, Tremetex, Trexeron, Trixilem, WR-19039, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Mycophenolate Mofetil, CellCept, MMF, Myeloablative Conditioning, Myeloablation, Myeloablative, Myeloablative Cytoreduction, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Rituximab, ABP 798, BI 695500, BI-695500, BI695500, Blitzima, C2B8 Monoclonal Antibody, Chimeric Anti-CD20 Antibody, CT-P10, IDEC 102, IDEC-102, IDEC-C2B8, IDEC-C2B8 Monoclonal Antibody, IDEC102, Ikgdar, Mabtas, MabThera, Monoclonal Antibody IDEC-C2B8, PF 05280586, PF-05280586, PF05280586, Riabni, Ritemvia, Rituxan, Rituximab ABBS, Rituximab ARRX, Rituximab Biosimilar ABP 798, Rituximab Biosimilar BI 695500, Rituximab Biosimilar CT-P10, Rituximab Biosimilar GB241, Rituximab Biosimilar IBI301, Rituximab Biosimilar JHL1101, Rituximab Biosimilar PF-05280586, Rituximab Biosimilar RTXM83, Rituximab Biosimilar SAIT101, Rituximab Biosimilar SIBP-02, rituximab biosimilar TQB2303, Rituximab PVVR, Rituximab-abbs, Rituximab-arrx, Rituximab-blit, Rituximab-pvvr, Rituximab-rite, Rituximab-rixa, Rituximab-rixi, Rixathon, Riximyo, RTXM 83, RTXM-83, RTXM83, Ruxience, Truxima, T-Cell Depletion Therapy, T-Cell Depletion, T-Lymphocyte Depletion Therapy, Tacrolimus, FK 506, FK-506, FK506, Fujimycin, Hecoria, Prograf, Protopic, Tacforius, Thiotepa, 1,1',1''-Phosphinothioylidynetrisaziridine, Girostan, N,N', N''-Triethylenethiophosphoramide, Oncotiotepa, SH 105, SH-105, SH105, STEPA, Tepadina, Tepylute, TESPA, Tespamin, Tespamine, Thio-Tepa, Thiofosfamide, Thiofozil, Thiophosphamide, Thiophosphoamide, Thiophosphoramide, Thiotef, Tifosyl, TIO TEF, Tio-tef, Triethylene Thiophosphoramide, Triethylenethiophosphoramide, Tris(1-aziridinyl)phosphine sulfide, TSPA, WR 45312, Total-Body Irradiation, SCT_TBI, TBI, Total Body Irradiation, Whole Body, Whole Body Irradiation, Whole-Body Irradiation
Children's Oncology Group
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome
12/27
12/27
NCT03266627: Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

Recruiting
2
20
US
cytotoxic t-lymphocytes, viral specific CTLs
New York Medical College, Children's Hospital of Philadelphia, Medical College of Wisconsin, Nationwide Children's Hospital, Johns Hopkins University, University of California, San Francisco, University of Colorado, Denver, Indiana University, Washington University School of Medicine, University of California, Los Angeles
Adenovirus, Primary Immune Deficiency Disorder
12/25
12/26
NCT04197596: Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)

Recruiting
1/2
40
US
BK CTL
New York Medical College, Children's Hospital of Philadelphia, Medical College of Wisconsin, Nationwide Children's Hospital, Johns Hopkins University, University of California, San Francisco
Viral Infection, Primary Immune Deficiency Disorder
12/24
06/25
17-CD33CART, NCT03971799: Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting
1/2
52
US
CD33CART autologous, CD33CART allogeneic
Center for International Blood and Marrow Transplant Research, National Marrow Donor Program, St. Baldrick's Foundation
Acute Myelogenous Leukemia
12/29
12/39
NCT04240808: Study of Feasibility and Safety of UCD19 Chimeric Antigen Receptor (CAR) T Cells in Adult Subjects With Relapsed/Refractory (R/R) B-Cell Non-Hodgkin's Lymphoma (B-NHL)

Active, not recruiting
1
11
US
UCD19 CAR T Cells
University of Colorado, Denver
Non Hodgkin Lymphoma
03/23
12/24
NCT01351545: A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Recruiting
N/A
99999
US
A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)
Center for International Blood and Marrow Transplant Research, National Marrow Donor Program
Hematologic Malignancies, Inherited Disorders of Metabolism, Inherited Abnormalities of Platelets, Histiocytic Disorders, Acute Myelogenous Leukemia (AML or ANLL), Acute Lymphoblastic Leukemia (ALL), Other Acute Leukemia, Chronic Myelogenous Leukemia (CML), Myelodysplastic (MDS) / Myeloproliferative (MPN) Diseases, Other Leukemia, Hodgkin Lymphoma, Non-hodgkin Lymphoma, Multiple Myeloma/ Plasma Cell Disorder (PCD), Inherited Abnormalities of Erythrocyte Differentiation or Function, Disorders of the Immune System, Autoimmune Diseases, Severe Aplastic Anemia
10/41
10/41
Aquilante, Christina L
NCT01686191: Genetic Predictors of Renal Dysfunction Following Heart Transplantation

Active, not recruiting
N/A
300
US
University of Colorado, Denver, National Jewish Health
Heart Transplantation, Chronic Renal Insufficiency
12/25
12/25
West, David
NCT06007196: Evaluation of Non-invasive Continuous Hemodynamic Measurement From Task Force CORE

Not yet recruiting
N/A
70
Europe
non-invasive device (Task Force CORE(R) and Task Force CARDIO(R)
Medical University of Vienna, Medical University of Graz
Hemodynamic Measurement, Non-invasive, Cardiac Output
08/24
09/24
Fisher, Jennifer O
NCT05462821: Full-Time Occlusion Therapy for Intermittent Exotropia in Children

Recruiting
3
72
US
Eye Patch
Jaeb Center for Health Research, National Eye Institute (NEI), Pediatric Eye Disease Investigator Group
Intermittent Exotropia
06/25
06/25
ATS23, NCT06380517: Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

Recruiting
3
238
US
Luminopia, Eye Patch
Jaeb Center for Health Research, National Eye Institute (NEI), Pediatric Eye Disease Investigator Group
Amblyopia
12/26
05/27
NCT03631992: Snacks, Smiles and Taste Preferences

Completed
N/A
172
US
Low Sweet, Regular Sweet
Temple University, Monell Chemical Senses Center, National Institute on Deafness and Other Communication Disorders (NIDCD)
Development, Child
10/24
10/24
NCT06108128: Food for Thought: Executive Functioning Around Eating Among Children

Recruiting
N/A
125
US
Executive functioning observational tasks
Temple University, Baylor College of Medicine, University of Nevada, Reno
Self-regulation, Appetitive Behavior, Eating Behavior, Child Obesity
05/25
05/25
NCT06111040: Nurturing Needs Study: Parenting Food Motivated Children

Recruiting
N/A
750
US
Measurement, Eating in the absence of hunger, Relative reinforcing value of food
Temple University, Baylor College of Medicine, University of Minnesota
Parenting, Eating Behavior, Diet, Healthy, Pediatric Obesity
10/27
10/27
Corboy, John
BEAT-MS, NCT04047628: Best Available Therapy Versus Autologous Hematopoetic Stem Cell Transplant for Multiple Sclerosis

Recruiting
3
156
US
Autologous Hematopoietic Stem Cell Transplantation, AHSCT, Best Available Therapy (BAT), natalizumab (Tysabri®), alemtuzumab (Campath®, Lemtrada®), ocrelizumab (Ocrevus®), rituximab (Rituxan®), cladribine (Mavenclad®), ofatumumab (Kesimpta®), ublituximab (BRIUMVI™)
National Institute of Allergy and Infectious Diseases (NIAID), Immune Tolerance Network (ITN), Blood and Marrow Transplant Clinical Trials Network, PPD DEVELOPMENT, LP, Rho Federal Systems Division, Inc.
Relapsing Multiple Sclerosis, Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
10/26
10/29
RISEMS, NCT03586986: Risk Factors in Early Multiple Sclerosis

Recruiting
N/A
300
US
Brain MRI, Blood analysis, Bioscreen, Symbol Digit Modality Test (SDMT)
University of Colorado, Denver, Colorado School of Public Health
Multiple Sclerosis, Magnetic Resonance Imaging, Biomarkers, Clinically Isolated Syndrome, Radiologically Isolated Syndrome
05/24
05/24
Rasouli, Neda
SIB, NCT04979130: Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus

Recruiting
4
42
US
Semaglutide, Ozempic, PDS290 pen-injector, Placebo
University of Colorado, Denver, Novo Nordisk A/S
Type 2 Diabetes, Chronic Inflammation, Intestinal Permeability
12/23
12/23
TRANSCEND-T2D-2, NCT06260722: Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor

Recruiting
3
1250
Canada, US, RoW
Retatrutide, LY3437943, Semaglutide
Eli Lilly and Company
Diabetes Mellitus, Type 2
12/26
03/27
NCT06292013: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Recruiting
3
12500
Europe, Canada, Japan, US, RoW
Lepodisiran Sodium, LY3819469, Placebo
Eli Lilly and Company
Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a)
03/29
03/29
NCT06383390: The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

Recruiting
3
10000
Europe, Canada, US, RoW
Retatrutide, LY3437943, Placebo
Eli Lilly and Company
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
02/29
02/29
QWINT-1, NCT05662332: A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time

Completed
3
795
US, RoW
Insulin Efsitora Alfa, LY3209590 and Basal Insulin-FC, Insulin Glargine
Eli Lilly and Company
Type 2 Diabetes, T2D
07/24
07/24
ACHIEVE-4, NCT05803421: A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk

Active, not recruiting
3
2749
Europe, US, RoW
Orforglipron, LY3502970, Insulin Glargine
Eli Lilly and Company
Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease
09/25
01/26
ATTAIN-1, NCT05869903: A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

Active, not recruiting
3
3000
Europe, Japan, US, RoW
Orforglipron, LY3502970, Placebo
Eli Lilly and Company
Obesity, Overweight, Overweight or Obesity
07/25
07/27
SURMOUNT-MMO, NCT05556512: A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

Active, not recruiting
3
15374
Europe, Canada, Japan, US, RoW
Tirzepatide, LY3298176, Placebo
Eli Lilly and Company
Obesity, Overweight
10/27
10/27
NCT05166382: Impact of SomaSignal Tests on the Choice of Glucose-lowering Medications

Active, not recruiting
N/A
350
US
Informed of results from SomaSignal Cardiovascular Risk Test in Type 2 Diabetes (CVD-T2D), Informed, Not informed of results from SomaSignal Cardiovascular Risk Test in Type 2 Diabetes (CVD-T2D), Uninformed
University of Colorado, Denver, SomaLogic, Inc.
Type 2 Diabetes, Cardiovascular Diseases
01/24
01/24
RADIANT, NCT05544266: Rare and Atypical Diabetes Network

Recruiting
N/A
2000
US
University of South Florida, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Diabetes Mellitus Progression, Glucose Intolerance, Glucose Metabolism Disorders, Metabolic Disease, Endocrine; Complications, Endocrine System Diseases
09/30
09/30
Ho, Michael
NCT04823273: Blood Transfusion Reduction - QI Project

Completed
N/A
1640
US
General improvement, In-line help text, Interruptive alert
University of Colorado, Denver
Blood Transfusion
04/22
10/22
NCT03973931: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications

Active, not recruiting
N/A
9501
US
Nudge
University of Colorado, Denver, National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Adherence, Medication, Medication Adherence, Diabetes Mellitus, Hypertension, Hyperlipidemias, Coronary Artery Disease, Atrial Fibrillation
01/24
06/24
Bota, Daniela
NCT01903330: ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme

Checkmark Interim results in combination with ERC1671/GM CSF/cyclophosphamide for recurrent glioblastoma
Aug 2020 - Aug 2020: Interim results in combination with ERC1671/GM CSF/cyclophosphamide for recurrent glioblastoma
Active, not recruiting
2
84
US
ERC1671, Gliovac, GM-CSF, Leukine®, sargramostim, Cyclophosphamide, 2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate, Oral Control (Sucrose pill), Injectable control (Sodium Chloride Injection United States Pharmacopeia (USP) (0.9%)), Bevacizumab/Bevacizumab Biosimilar, Avastin, MVASI, bevacizumab-awwb, bevacizumab-bvzr, ZIRABEV
Epitopoietic Research Corporation, University of California, Irvine
Glioblastoma, Gliosarcoma
03/23
03/23
NCT03450850: Study Of NOVOTTF-200A In Bevacizumab-Naive Subjects With Recurrent Grade III Malignant Astrocytoma

Active, not recruiting
2
34
US
NOVOTTF-200A
Daniela A. Bota, NovoCure Ltd.
Astrocytoma, Grade III
09/23
09/24
NCT04762069 / 2021-003659-40: A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Hourglass Jan 2023 - Jun 2023 : Data from trial for glioblastoma
Hourglass Jul 2022 - Dec 2022 : Interim analysis data from trial for glioblastoma in adults
Active, not recruiting
2
210
Europe, US
Berubicin, Berubicin Hydrochloride, Lomustine, Lomustine Capsules, CCNU, CeeNU, Gleostine
CNS Pharmaceuticals, Inc., Worldwide Clinical Trials
Glioblastoma Multiforme, Adult
12/24
03/25
A071401, NCT02523014: Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients with Progressive Meningiomas

Recruiting
2
124
US
Vismodegib, GDC-0449, FAK Inhibitor GSK2256098, Capivasertib, AZD5363, Abemaciclib
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI), GlaxoSmithKline, Genentech, Inc., Brain Science Foundation
Intracranial Meningioma, Recurrent Meningioma, NF2 Gene Mutation
01/26
01/28
SWOG S1609, NCT02834013: Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Checkmark From cohort 36 of DART trial in combination with Yervoy for metaplastic breast cancer
Jun 2020 - Jun 2020: From cohort 36 of DART trial in combination with Yervoy for metaplastic breast cancer
Checkmark From cohort 36 of DART trial in combination with Opdivo for metaplastic breast cancer
Jun 2020 - Jun 2020: From cohort 36 of DART trial in combination with Opdivo for metaplastic breast cancer
Checkmark In combination with yervoy in aggressive neuroendocrine tumors
More
Active, not recruiting
2
818
US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, BMS 734016, BMS-734016, BMS734016, Ipilimumab Biosimilar CS1002, MDX 010, MDX-010, MDX-CTLA4, MDX010, Yervoy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo
National Cancer Institute (NCI)
Acinar Cell Carcinoma, Adenoid Cystic Carcinoma, Adrenal Cortical Carcinoma, Adrenal Gland Pheochromocytoma, Anal Canal Neuroendocrine Carcinoma, Anal Canal Undifferentiated Carcinoma, Angiosarcoma, Apocrine Neoplasm, Appendix Mucinous Adenocarcinoma, Bartholin Gland Transitional Cell Carcinoma, Basal Cell Carcinoma, Bladder Adenocarcinoma, Breast Metaplastic Carcinoma, Cervical Adenocarcinoma, Cholangiocarcinoma, Chordoma, Colorectal Squamous Cell Carcinoma, Desmoid Fibromatosis, Endometrial Transitional Cell Carcinoma, Endometrioid Adenocarcinoma, Esophageal Neuroendocrine Carcinoma, Esophageal Undifferentiated Carcinoma, Extrahepatic Bile Duct Carcinoma, Extramammary Paget Disease, Fallopian Tube Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma, Fibromyxoid Tumor, Gallbladder Carcinoma, Gastric Neuroendocrine Carcinoma, Gastric Squamous Cell Carcinoma, Gastric Undifferentiated Carcinoma, Gastrointestinal Stromal Tumor, Gestational Trophoblastic Tumor, Giant Cell Carcinoma, Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type, Intestinal Neuroendocrine Carcinoma, Intrahepatic Cholangiocarcinoma, Lung Neuroendocrine Tumor, Lung Sarcomatoid Carcinoma, Major Salivary Gland Carcinoma, Malignant Neoplasm of Unknown Primary, Malignant Odontogenic Neoplasm, Malignant Peripheral Nerve Sheath Tumor, Malignant Solid Neoplasm, Malignant Testicular Sex Cord-Stromal Tumor, Metastatic Pituitary Neuroendocrine Tumor, Minimally Invasive Lung Adenocarcinoma, Mixed Mesodermal (Mullerian) Tumor, Mucinous Adenocarcinoma, Mucinous Cystadenocarcinoma, Nasal Cavity Adenocarcinoma, Nasal Cavity Carcinoma, Nasopharyngeal Carcinoma, Nasopharyngeal Low Grade Papillary Adenocarcinoma, Nasopharyngeal Undifferentiated Carcinoma, Oral Cavity Carcinoma, Oropharyngeal Undifferentiated Carcinoma, Ovarian Adenocarcinoma, Ovarian Germ Cell Tumor, Ovarian Mucinous Adenocarcinoma, Ovarian Squamous Cell Carcinoma, Ovarian Transitional Cell Carcinoma, Pancreatic Acinar Cell Carcinoma, Pancreatic Neuroendocrine Carcinoma, Paraganglioma, Paranasal Sinus Adenocarcinoma, Paranasal Sinus Carcinoma, Parathyroid Gland Carcinoma, PEComa, Penile Squamous Cell Carcinoma, Peritoneal Mesothelial Neoplasm, Placental Choriocarcinoma, Primary Peritoneal High Grade Serous Adenocarcinoma, Pseudomyxoma Peritonei, Rare Disorder, Scrotal Squamous Cell Carcinoma, Seminal Vesicle Adenocarcinoma, Seminoma, Serous Cystadenocarcinoma, Small Intestinal Adenocarcinoma, Small Intestinal Squamous Cell Carcinoma, Spindle Cell Neoplasm, Teratoma With Somatic-Type Malignancy, Testicular Non-Seminomatous Germ Cell Tumor, Thyroid Gland Carcinoma, Tracheal Carcinoma, Transitional Cell Carcinoma, Ureter Adenocarcinoma, Ureter Squamous Cell Carcinoma, Urethral Adenocarcinoma, Urethral Squamous Cell Carcinoma, Vaginal Adenocarcinoma, Vaginal Squamous Cell Carcinoma, Not Otherwise Specified, Vulvar Carcinoma
05/26
05/26
NCT03935685: Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ

Active, not recruiting
2
120
US
Mirtazapine (Remeron)
University of California, Irvine
Glioma of Brain
12/24
12/24
 

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