| Hudson, Chris |
| Completed | N/A | 813 | Canada | | Optina Diagnostics Inc. | Healthy | 03/24 | 03/24 | | |
| Giangregorio, Lora |
NCT04663685: MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Training Combined With Nutrition Education for Older Pre-frail Adults. |
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| Completed | N/A | 30 | Canada | Exercise program, Nutrition education | University of Waterloo | Arthritis, Cancer, Cardiovascular Diseases, Chronic Lung Disease, Congestive Heart Failure, Diabetes, Hypertension, Kidney Diseases, Obesity, Osteoporosis, Stroke, Frailty | 04/21 | 10/21 | | |
VIVA, NCT06650410: Virtual Intervention for Vertebral frActure: a Pilot, Feasibility Study for a Multicentre Randomized Controlled Trial |
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| Not yet recruiting | N/A | 32 | Canada | Virtual Intervention for Vertebral Fractures (VIVA) | University of Waterloo, Unity Health, Arthritis Research Centre of Canada, Hamilton Health Sciences Corporation, McGill University Health Centre/Research Institute of the McGill University Health Centre | Osteoporosis, Fractures, Spinal | 12/25 | 12/25 | | |
NCT05541432: Finding the Optimal Resistance Training Intensity For Your Bones |
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| Recruiting | N/A | 324 | Canada | Supervised strength training (group 1), Supervised strength training (group 2), Home exercise | University of Waterloo, Canadian Institutes of Health Research (CIHR), University of Saskatchewan, University Health Network, Toronto | Osteoporosis, Osteopenia | 09/26 | 09/26 | | |
| Jones, Lyndon |
COLLIE, NCT04297618: The Effect of Xiidra on Comfort and Dryness in Symptomatic Contact Lens Wearers |
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| Completed | 4 | 45 | Canada | Xiidra, Lifitegrast | University of Waterloo, Novartis | Dry Eye | 04/24 | 04/24 | | |
NCT03818880: Choroidal Response to Novel Spectacle Lens to Control Myopia Progression |
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| Active, not recruiting | N/A | 10 | Canada | Novel spectacle lens design | SightGlass Vision, Inc., University of Waterloo | Myopia, Progressive | 04/22 | 03/26 | | |
EX-MKTG-130, NCT05166902: Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use |
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| Completed | N/A | 67 | Canada, US | Lens A (comfilcon A lens), Lens B (lehfilcon A lens) | Coopervision, Inc., CORE | Ametropia | 07/22 | 07/22 | | |
EX-MKTG-89, NCT04886479: Comparing Silicone Hydrogel Contact Lens Wearers to Hydrogel Contact Lens Wearers and Non-lens Wearers |
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| Completed | N/A | 22 | Europe, Canada | Control, Test Lens | Coopervision, Inc. | Myopia | 10/22 | 10/22 | | |
EX-MKTG-132, NCT05333965: To Evaluate The Performance Of Two Monthly Replacement Silicone Hydrogel Contact Lenses After 1-month Of Wear |
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| Completed | N/A | 26 | Canada | Lens A (lehfilcon A lens), Lens B (comfilcon A lens) | Coopervision, Inc. | Myopia | 09/22 | 09/22 | | |
| Completed | N/A | 60 | US | Control Lens, Test Lens | Coopervision, Inc., CORE | Presbyopia | 02/23 | 02/23 | | |
| Completed | N/A | 59 | Canada, US | Control Lens (stenfilcon A), Test Lens (senofilcon A) | Coopervision, Inc., Centre for Ocular Research & Education, Canada | Presbyopia | 06/23 | 06/23 | | |
ASH-2, NCT05617794: Effect of Diffusion Optics Technology (DOT) Spectacle Lenses on Choroidal Thickness |
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| Active, not recruiting | N/A | 30 | Canada | Diffusion Optics Technology (DOT) Pattern Spectacle Lens, Control Spectacle Lens | SightGlass Vision, Inc., University of Waterloo | Myopia, Myopia Progression, Juvenile Myopia | 04/23 | 03/26 | | |
NCT05079321: Ocular Effects of Scleral Lens Wear on Dry Eye Patients |
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| Completed | N/A | 24 | Canada | Hydra-PEG, Uncoated | University of Waterloo | Dry Eye | 08/23 | 08/23 | | |
EX-MKTG-148, NCT05805150: Performance Evaluation of Daily Disposable Contact Lenses in Habitual Lens Wearers Who Use Digital Devices Frequently |
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| Completed | N/A | 69 | US | Control Lens (stenfilcon A), Test Lens (senofilcon A) | Coopervision, Inc., Centre for Ocular Research & Education, Canada | Myopia | 06/23 | 06/23 | | |
NCT05973409: Evaluation of Onefit Scleral Lenses in the Mangement of Dry Eye |
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| Not yet recruiting | N/A | 10 | Canada | scleral lens | Coopervision, Inc. | Dry Eye | 08/23 | 08/23 | | |
| Completed | N/A | 68 | Canada, US | Control Contact Lens (stenfilcon A), Test Contact Lens (senofilcon A) | Coopervision, Inc., Centre for Ocular Research & Education, Canada | Myopia | 06/23 | 06/23 | | |
NCT06046209: Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens |
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| Completed | N/A | 30 | Canada | Control Lens, Test Lens | Coopervision, Inc., Centre for Ocular Research & Education, Canada | Myopia | 11/23 | 11/23 | | |
NCT06170658: 1 Week Crossover Dispensing Study Between Two Soft Contact Lenses |
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| Recruiting | N/A | 30 | Canada | Test Lenses, Control Lenses | Coopervision, Inc. | Myopia | 02/24 | 07/24 | | |
FOX, NCT06308666: Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use |
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| Completed | N/A | 41 | Canada | Delefilcon A contact lenses, DAILIES TOTAL1® | University of Waterloo, Alcon Research | Myopia | 10/24 | 10/24 | | |
GIRAFFE, NCT06369987: Visual Performance of Dailies Total1 Multifocal and Acuvue Oasys Max 1-Day Multifocal in Presbyopic Lens Wearers |
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| Completed | N/A | 28 | Canada | Deleficon A (multifocal), Dailies Total1 Multifocal, Senofilcon A (multifocal), ACUVUE OASYS MAX 1-DAY Multifocal | University of Waterloo, Alcon Research | Presbyopia | 11/24 | 11/24 | | |
NCT06431061: Clinical Evaluation of Proclear Toric and Biofinity Toric |
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| Active, not recruiting | N/A | 40 | Canada | Lens A (omafilcon B), Lens B (comfilcon A) | Coopervision, Inc. | Astigmatism | 08/24 | 08/24 | | |
| Mourtzakis, Marina |
| Active, not recruiting | N/A | 200 | Canada | Exercise | University of Waterloo | Cancer | 12/24 | 12/26 | | |
| Middleton, Laura |
SYN2, NCT05375513: SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@home) |
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| Recruiting | N/A | 275 | Canada | PMI@Home, Brain Health Pro | Lawson Health Research Institute | Mild Cognitive Impairment | 11/25 | 12/26 | | |
NCT06078748: The Lifestyle Exercise and Diet Trial (LEAD) 2.0 |
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| Recruiting | N/A | 140 | Canada | EX, Combined aerobic and resistance exercise, DIET, Brain-healthy diet education and counseling, STRETCH, Stretching and toning exercise, ED, Brain Health Education and Discussion | University of Waterloo, Baycrest, Université de Montréal, University of Ottawa | Subjective Cognitive Decline | 10/25 | 10/25 | | |
| Hammond, David |
NCT05010759: Study of Focal Ablation of the Prostate With NanoTherm® Therapy System for Intermediate-Risk Prostate Cancer |
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| Terminated | N/A | 3 | US | NanoTherm Ablation | MagForce USA | Prostate Cancer | 07/23 | 07/23 | | |
| Ngo, William |
NCT05957211: Improving Drop Instillation Comfort of a Cyclosporine A Solution |
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| Completed | N/A | 40 | Canada | 0.09% cyclosporine A ophthalmic solution, Cequa | University of Waterloo, Sun Pharmaceutical Industries Limited | Dry Eye Disease | 02/24 | 02/24 | | |
| Cheong, Allen MY |
NCT04560504: Effectiveness of Oculomotor Training in Parkinson's Disease |
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| Completed | N/A | 27 | RoW | Control Group, Oculomotor Training Group | The Hong Kong Polytechnic University, University of California, Berkeley, Deakin University, Chinese University of Hong Kong, Hospital Authority, Hong Kong | Parkinson Disease, Oculomotor; Disorder | 08/22 | 12/22 | | |
NCT04846140: Optimal Non-invasive Brain Stimulation for Peripheral Vision |
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| Recruiting | N/A | 40 | RoW | transcranial electrical stimulation (tES) | The Hong Kong Polytechnic University, Chinese University of Hong Kong, The University of Hong Kong, University of Waterloo, Hong Kong Metropolitan University, Otto-von-Guericke University Magdeburg | Glaucoma | 07/25 | 09/25 | | |
NCT04762368: Learning Study: Improving Vision in Adults With Macular Degeneration |
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| Recruiting | N/A | 30 | Canada, RoW | Active anodal tDCS, Sham anodal tDCS | University of Waterloo, The Hong Kong Polytechnic University | Macular Degeneration | 12/24 | 12/24 | | |
NCT06000865: Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE |
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| Recruiting | N/A | 56 | RoW | Action video game training, Conventional physical training | The Hong Kong Polytechnic University, University of Waterloo, The University of Hong Kong, University of Leicester | Glaucoma, Visual Impairment | 12/24 | 01/25 | | |
NCT05874258: Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT) - Randomized Controlled Trial Using Combined Perceptual Learning and Transcranial Electrical Stimulation for Vision Enhancement |
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| Recruiting | N/A | 144 | RoW | Real-PL training + Real-tES(tDCS), Real-PL training + Sham-tES (tDCS), Placebo-PL training + Sham-tES (tDCS) | The Hong Kong Polytechnic University, The University of Hong Kong, University of Waterloo, University of Magdeburg | Glaucoma | 06/26 | 12/26 | | |
| Recruiting | N/A | 36 | Canada, RoW | Spectacles | Centre for Eye and Vision Research, The Hong Kong Polytechnic University, University of Waterloo | Amblyopia | 11/26 | 05/27 | | |
| Johnson, Jane C |
NCT06072599: Use of Osteopathic Manipulative Treatment for Non-musculoskeletal Conditions |
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| Enrolling by invitation | N/A | 1000 | US | | A.T. Still University of Health Sciences, DO-Touch.NET | Manipulation, Osteopathic | 03/25 | 03/25 | | |
| Moezzi, Amir |
PROTECT, NCT05159765: Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial |
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| Recruiting | N/A | 144 | Canada, US, RoW | Single vision contact lenses, Multifocal contact lenses | Visioneering Technologies, Inc | Myopia | 08/25 | 08/25 | | |
| Russell, Caryl |
| Active, not recruiting | N/A | 200 | Canada | Exercise | University of Waterloo | Cancer | 12/24 | 12/26 | | |
| Sharratt, Michael |
| Active, not recruiting | N/A | 200 | Canada | Exercise | University of Waterloo | Cancer | 12/24 | 12/26 | | |
| Laura, Middleton |
| Recruiting | N/A | 2300 | Canada | | McGill University, Canadian Institutes of Health Research (CIHR), Alzheimer Society of Canada, Sanofi, New Brunswick Health Research Foundation, Saskatchewan Health Research Foundation, Women's Brain Health Initiative, Michael Smith Foundation for Health Research, Alzheimer's Research UK, Alberta Prion Research Institute, Nova Scotia Health Research Foundation, Eli Lilly and Company, Canadian Nurses Foundation (CNF), Ontario Brain Institute, Consortium pour l'Identification precoce du Maladie Alzheimer du Quebec, Pfizer, Canadian Consortium on Neurodegeneration in Aging | Dementia | 09/23 | 09/23 | | |
| Bell, Kirsten E |
| Recruiting | N/A | 24 | Canada | High-fat test meal | Kirsten Bell, McMaster University | Healthy Nutrition | 09/22 | 05/23 | | |
| Thompson, Ben |
XmAb20717-05, NCT05032040: A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies |
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| Recruiting | 2 | 170 | US | vudalimab | Xencor, Inc., ICON plc | Ovarian Cancer, Clear Cell Carcinoma, Endometrial Cancer, Cervical Carcinoma, Metastatic Castration-Resistant Prostate Cancer (mCRPC) | 10/25 | 12/25 | | |
| Completed | 1 | 198 | US | XmAb®23104, Yervoy® (ipilimumab) | Xencor, Inc., ICON plc | Melanoma (Excluding Uveal Melanoma), Cervical Carcinoma, Pancreatic Carcinoma, Breast Carcinoma That is Estrogen Receptor, Progesterone Receptor, and Her2 Negative, Hepatocellular Carcinoma, Urothelial Carcinoma, Squamous Cell Carcinoma of the Head and Neck, Nasopharyngeal Carcinoma, Renal Cell Carcinoma, Colorectal Carcinoma, Endometrial Carcinoma, Non-small Cell Lung Carcinoma, Small Cell Lung Cancer, Gastric or Gastroesophageal Junction Adenocarcinoma, Advanced Solid Tumors, Undifferentiated Pleomorphic Sarcoma | 02/24 | 02/24 | | |
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XmAb808-01, NCT05585034: Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors |
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| Recruiting | 1 | 220 | US | XmAb®808, Keytruda® (pembrolizumab) | Xencor, Inc. | Head and Neck Squamous Cell Carcinoma, Melanoma Excluding Uveal Melanoma, Non-small Cell Lung Cancer, Squamous or Non-squamous, Urothelial Carcinoma, Renal Cell Carcinoma, Clear Cell, Castration-resistant Prostate Cancer, Ovarian Cancer, Epithelial, TNBC - Triple-Negative Breast Cancer, Colorectal Cancer | 12/27 | 12/27 | | |
NCT04086524: A Patch Free Treatment for Young Children With Amblyopia |
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| Completed | N/A | 34 | US, RoW | Binocular cartoon treatment at home, Patching, occlusion therapy, penalization, Binocular cartoon treatment in office | University of Waterloo, Retina Foundation of the Southwest, McGill University, Queensland University of Technology | Amblyopia, Binocular Vision Disorder | 05/23 | 11/23 | | |
NCT04762368: Learning Study: Improving Vision in Adults With Macular Degeneration |
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| Recruiting | N/A | 30 | Canada, RoW | Active anodal tDCS, Sham anodal tDCS | University of Waterloo, The Hong Kong Polytechnic University | Macular Degeneration | 12/24 | 12/24 | | |
| Active, not recruiting | N/A | 249 | Europe | WORKWELL, Vocational rehabilitation, Work rehabilitation, Control, written work self-help information pack | University of Salford, University of Central Lancashire, University of Manchester, Versus Arthritis | Arthritis, Rheumatoid, Arthritis, Psoriatic, Arthritis, Inflammatory | 04/24 | 12/24 | | |
| Kelly, Allison |
| Recruiting | 3 | 330 | US | Candin, Intradermal Solution, Placebo | Nielsen BioSciences, Inc. | Common Warts (Verruca Vulgaris) | 06/25 | 06/25 | | |
NCT06200675: Understanding and Intervening With State Shame and Self-criticism |
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| Completed | N/A | 348 | Canada | Compassion-based intervention, Logic-based intervention, Placebo control condition | University of Waterloo | Self-Criticism | 12/23 | 12/23 | | |
NCT05284123: The Impact of a Self-Compassion Intervention on Shame and Mental Health Treatment-Seeking |
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| Completed | N/A | 265 | Canada | Self-compassion workshop, Mental health literacy workshop, Control workshop | University of Waterloo | Psychological Distress | 05/24 | 05/24 | | |
NCT04174703: Preparing for Eating Disorders Treatment Through Compassionate Letter-Writing |
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| Enrolling by invitation | N/A | 160 | Canada | Self-compassionate letter-writing intervention | University of Waterloo, St. Joseph's Healthcare Hamilton | Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Compassion | 12/24 | 12/24 | | |
| Tan, Ken |
| Active, not recruiting | N/A | 1500 | RoW | TEACH-PD Training Curriculum, Current standard PD training | The University of Queensland, The HOME Network, Australia and New Zealand Dialysis and Transplant Registry, New Zealand Peritoneal Dialysis Registry | Kidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis, Peritoneal Dialysis Catheter Exit Site Infection, Peritoneal Dialysis Catheter Tunnel Infection | 03/25 | 04/25 | | |
| Recruiting | N/A | 36 | Canada, RoW | Spectacles | Centre for Eye and Vision Research, The Hong Kong Polytechnic University, University of Waterloo | Amblyopia | 11/26 | 05/27 | | |
| Thompson, Benjamin |
DUET-4, NCT03849469: A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors |
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| Completed | 1 | 78 | US | XmAb®22841, Pembrolizumab (Keytruda®) | Xencor, Inc., ICON Clinical Research | Melanoma, Cervical Carcinoma, Pancreatic Carcinoma, Triple Negative Breast Cancer, Hepatocellular Carcinoma, Urothelial Carcinoma, Squamous Cell Carcinoma of the Head and Neck, Nasopharyngeal Carcinoma, Renal Cell Carcinoma, Non-small Cell Lung Carcinoma, Small Cell Lung Carcinoma, Gastric or Gastroesophageal Junction Adenocarcinoma, Advanced or Metastatic Solid Tumors, Prostate Carcinoma, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma, Intrahepatic Cholangiocarcinoma, Squamous Cell Anal Cancer, Squamous Cell Penile Carcinoma, Squamous Cell Vulvar Carcinoma, Colorectal Carcinoma, Endometrial Carcinoma | 02/23 | 02/23 | | |
NCT05913063: Direct Discrimination of Quantum States by the Human Eye |
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| Recruiting | N/A | 50 | RoW | Structured Light Imaging Microscopy | Centre for Eye and Vision Research, University of Waterloo, The Hong Kong Polytechnic University | Age-Related Macular Degeneration | 07/29 | 10/29 | | |
| Recruiting | N/A | 36 | Canada, RoW | Spectacles | Centre for Eye and Vision Research, The Hong Kong Polytechnic University, University of Waterloo | Amblyopia | 11/26 | 05/27 | | |
| Kraus, Giselle |
NCT05284123: The Impact of a Self-Compassion Intervention on Shame and Mental Health Treatment-Seeking |
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| Completed | N/A | 265 | Canada | Self-compassion workshop, Mental health literacy workshop, Control workshop | University of Waterloo | Psychological Distress | 05/24 | 05/24 | | |
| Sullivan, Kylie |
NCT05541432: Finding the Optimal Resistance Training Intensity For Your Bones |
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| Recruiting | N/A | 324 | Canada | Supervised strength training (group 1), Supervised strength training (group 2), Home exercise | University of Waterloo, Canadian Institutes of Health Research (CIHR), University of Saskatchewan, University Health Network, Toronto | Osteoporosis, Osteopenia | 09/26 | 09/26 | | |
| Dominelli, Paolo |
NCT05575180: Effect of Acetazolamide and Methazolamide on Hypoxic Exercise Performance |
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| Completed | 4 | 15 | Canada | Acetazolamide 250Mg Tab, Methazolamide Pill, Placebo | University of Waterloo, Wilderness Medical Society | High Altitude Effects | 02/24 | 02/24 | | |
| Neudorf, Bobby |
NCT06078748: The Lifestyle Exercise and Diet Trial (LEAD) 2.0 |
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| Recruiting | N/A | 140 | Canada | EX, Combined aerobic and resistance exercise, DIET, Brain-healthy diet education and counseling, STRETCH, Stretching and toning exercise, ED, Brain Health Education and Discussion | University of Waterloo, Baycrest, Université de Montréal, University of Ottawa | Subjective Cognitive Decline | 10/25 | 10/25 | | |
| Korlacka, Michelle |
NCT06200675: Understanding and Intervening With State Shame and Self-criticism |
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| Completed | N/A | 348 | Canada | Compassion-based intervention, Logic-based intervention, Placebo control condition | University of Waterloo | Self-Criticism | 12/23 | 12/23 | | |
| Varandas, Dave |
NCT05541432: Finding the Optimal Resistance Training Intensity For Your Bones |
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| Recruiting | N/A | 324 | Canada | Supervised strength training (group 1), Supervised strength training (group 2), Home exercise | University of Waterloo, Canadian Institutes of Health Research (CIHR), University of Saskatchewan, University Health Network, Toronto | Osteoporosis, Osteopenia | 09/26 | 09/26 | | |
