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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Finzel, Stephanie
OCEAN, NCT05263934 / 2021-005726-15: Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA)	Recruiting	3	160	Europe, Canada, Japan, US, RoW	Depemokimab, Mepolizumab, Placebo matching mepolizumab, Placebo matching depemokimab	GlaxoSmithKline	Eosinophilic Granulomatosis With Polyangiitis	10/25	11/25
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Active, not recruiting	2/3	301	Europe, Japan, US, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	09/25	09/25
Supady, Alexander
ReActiF-ICE, NCT05442710: Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy	Recruiting	2	142	Europe	ARTICE	Artcline GmbH, Zentrum für Klinische Studien Jena, CRO Kottmann	Sepsis, Severe	12/24	05/25