The Royal Marsden NHSHFT
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 7 Trials 
8 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Brown, Gina
EVIDENCE, NCT06646341: EMVI as a Determinant of Metastasis in Colorectal Cancer

Recruiting
N/A
100
Europe
Imperial College London
Colo-rectal Cancer
12/25
12/27
DOCUMAS, NCT02579278: Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion

Recruiting
N/A
100
Europe
Blood sample (mrEMVI positive patient), Blood sample (mrEMVI negative patient), Two blood samples are taken from each patient with mrEMVI negative tumours post chemoradiotherapy. One pre-surgery and one during surgery from a peripheral vein.
Imperial College London
Cancer, Rectal Cancer
12/26
12/29
COMET, NCT03303547: Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits

Recruiting
N/A
200
Europe
MRI mapping to guide pathological sampling of extranodal tumour deposits
Imperial College London, Pelican Cancer Foundation
Adenocarcinoma of the Rectum
12/26
12/31
SERENADE, NCT02246634: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI

Recruiting
N/A
282
Europe
Diffusion Weighted MRI scan
Imperial College London, Pelican Cancer Foundation
Colorectal Neoplasms, Neoplasm Metastases, Hepatic Neoplasms
12/26
12/31
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
NCT02292641: Beyond TME Origins

Recruiting
N/A
383
Europe
New Radiological Staging Classification system for patients with advanced and recurrent colorectal cancer undergoing pelvic exenterative surgery
Imperial College London, Pelican Cancer Foundation
Neoplasms, Adenocarcinoma, Carcinoma
12/26
12/31
TRIGGER, NCT02704520 / 2015-003009-40: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial

Recruiting
N/A
441
Europe
High resolution MRI scan, mrTRG assessment
Imperial College London
Rectal Cancer
12/26
12/36
PRESERVE, NCT04103372: Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery

Recruiting
N/A
200
Europe
MRI scan, Radiologist training
Imperial College London, Pelican Cancer Foundation, RM Partners West London Cancer Alliance
Rectal Cancer, Colo-rectal Cancer
12/26
12/31
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Brown, Gina
EVIDENCE, NCT06646341: EMVI as a Determinant of Metastasis in Colorectal Cancer

Recruiting
N/A
100
Europe
Imperial College London
Colo-rectal Cancer
12/25
12/27
DOCUMAS, NCT02579278: Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion

Recruiting
N/A
100
Europe
Blood sample (mrEMVI positive patient), Blood sample (mrEMVI negative patient), Two blood samples are taken from each patient with mrEMVI negative tumours post chemoradiotherapy. One pre-surgery and one during surgery from a peripheral vein.
Imperial College London
Cancer, Rectal Cancer
12/26
12/29
COMET, NCT03303547: Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits

Recruiting
N/A
200
Europe
MRI mapping to guide pathological sampling of extranodal tumour deposits
Imperial College London, Pelican Cancer Foundation
Adenocarcinoma of the Rectum
12/26
12/31
SERENADE, NCT02246634: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI

Recruiting
N/A
282
Europe
Diffusion Weighted MRI scan
Imperial College London, Pelican Cancer Foundation
Colorectal Neoplasms, Neoplasm Metastases, Hepatic Neoplasms
12/26
12/31
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
NCT02292641: Beyond TME Origins

Recruiting
N/A
383
Europe
New Radiological Staging Classification system for patients with advanced and recurrent colorectal cancer undergoing pelvic exenterative surgery
Imperial College London, Pelican Cancer Foundation
Neoplasms, Adenocarcinoma, Carcinoma
12/26
12/31
TRIGGER, NCT02704520 / 2015-003009-40: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial

Recruiting
N/A
441
Europe
High resolution MRI scan, mrTRG assessment
Imperial College London
Rectal Cancer
12/26
12/36
PRESERVE, NCT04103372: Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery

Recruiting
N/A
200
Europe
MRI scan, Radiologist training
Imperial College London, Pelican Cancer Foundation, RM Partners West London Cancer Alliance
Rectal Cancer, Colo-rectal Cancer
12/26
12/31

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