Maxima Medisch Centrum Trials

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Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Vreugdenhil, G

DRUP, NCT02925234 / 2015-004398-33: The Drug Rediscovery Protocol ( Trial)

Recruiting

1550

Europe

Panitumumab, Vectibix, Olaparib, Lynparza, Dabrafenib, Tafinlar, Nilotinib, Tasigna, Trametinib, Mekinist, Erlotinib, Tarceva, Trastuzumab and Pertuzumab (combination treatment), Herceptin + Perjeta, Vemurafenib and Cobimetinib (combination treatment), Zelboraf + Cotellic, Vismodegib, Erivedge, Regorafenib, Stivarga, Nivolumab, Opdivo, Afatinib, Giotrif, Dabrafenib and trametinib, Tafinlar and Mekinist, Ribociclib, Kisqali, Lenvatinib, Lenvima, Pembrolizumab, Keytruda, Durvalumab, MEDI4736, Rucaparib, Rubraca, Axitinib, Inlyta, Palbociclib, Ibrance, Crizotinib, Xalkori, Sunitinib, Sutent, Cabozantinib, Cabometyx, Abemaciclib, Verzenios, Alectinib, Alecensa, Atezolizumab and Bevacizumab, Tecentriq and Avastin, Ipilimumab and nivolumab, Yervoy and Opdivo, Entrectinib, Rozlytrek, Talazoparib, Talzenna, Dacomitinib, Vizimpro, Lorlatinib, Lorviqua, Erdafitinib, Balversa, Alpelisib, Piqray, Niraparib, Zejula, Pemigatinib, Pemazyre, Selpercatinib, Retsevmo, Tepotinib, Tepmetko

The Netherlands Cancer Institute, Amgen, AstraZeneca, Bayer, Bristol-Myers Squibb, Novartis, Roche Pharma AG, Merck Sharp & Dohme LLC, Boehringer Ingelheim, Ipsen, Eisai Inc., Pfizer, Clovis Oncology - Pharma and, Eli Lilly and Company, Janssen, LP, GlaxoSmithKline, Incyte Corporation, Dutch Cancer Society, Stelvio for Life

Cancer, Tumors, Neoplasm, Neoplasia

09/27

12/27

ORCHESTRA, NCT01792934: Chemotherapy and Maximal Tumor Debulking of Multi-organ Colorectal Cancer Metastases

Recruiting

N/A

478

Europe

XELOX regimen according to standard procedures, FOLFOX regimen according to standard procedures, Surgery, radiofrequency ablation (RFA), transarterial chemo-embolization using irinotecan drug-eluted beads ((DEBIRI-)TACE), stereotactic body radiation therapy (SBRT), Bevacizumab, tumor biopsy

Radboud University Medical Center, Erasmus Medical Center

Multi-organ Metastatic Colorectal Cancer

07/23

07/25

Secretary

NCT06366360: Immersive Virtual Reality Treatment for Unilateral Spatial Neglect

Recruiting

N/A

Europe

Immersive Virtual Reality Intervention, Conventional rehabilitation

Hopitaux de Saint-Maurice

Stroke, Unilateral Spatial Neglect

09/26

09/27

Wean-Trach, NCT05906888: Weaning with Tracheostomy - an Observational Study on Patient-centered Outcomes

Recruiting

N/A

150

Europe

Henrik Endeman, Franciscus &Vlietland

Weaning Failure, Mechanical Ventilation, Patient-centered Care

11/24

12/24

ARMANI, NCT04678583: Anatomical Resection of Liver MetAstases iN patIents With RAS-mutated Colorectal Cancer

Recruiting

N/A

240

Europe

Resection of colorectal liver metastases

Technische Universität Dresden, KKS Dresden, German Cancer Research Center

Colorectal Liver Metastasis

12/27

Simkens, L

PLCRC, NCT02070146: Prospective Data Collection Initiative on Colorectal Cancer

Recruiting

N/A

50000

Europe

Dutch Colorectal Cancer Group

Colorectal Cancer

01/50

01/51

Tick, L W

HO171, NCT06014489: A Trial to Assess Cobicistat Boosted Venetoclax in Combination With Azacitidine in Adult Patients With Newly Diagnosed AML

Recruiting

142

Europe

azacitidine, Venetoclax, Cobicistat

Stichting Hemato-Oncologie voor Volwassenen Nederland

AML, Adult

03/28

Dercksen, M W

Triple-B, NCT01898117 / 2013-001484-23: Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer

Active, not recruiting

304

Europe

Carbo/cyclo, Carboplatin, Cyclophosphamide, Carbo/cyclo + atezolizumab, Atezolizumab, Paclitaxel, Paclitaxel + Atezolizumab

The Netherlands Cancer Institute, Borstkanker Onderzoek Groep, Roche Pharma AG

Breast Cancer

12/24

12/30

SEQUEL-Breast, NCT05392608: SEQUence of Endocrine Therapy in Advanced Luminal Breast Cancer

Recruiting

130

Europe

Alpelisib 150 MG Oral Tablet [Piqray], Piqray, Fulvestrant, Faslodex

Borstkanker Onderzoek Groep, Novartis Pharma B.V., BOOG Study Center

Neoplasm, Breast, Congenital, Familial and Genetic Disorders

12/24

03/28

Lieverse, Louis

PULSE, NCT04828304: PLASOMA Ultimate Safety & Efficacy Study

Active, not recruiting

N/A

101

Europe

PLASOMA

Plasmacure, Diabetes Fonds, Pathology and Medical Microbiology

Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Burn Wound, Skin Graft, Infected Surgical Wound, Skin Flap

12/24

Youssef, Maggy

NVALT28, NCT04597671: Durvalumab and Low-dose PCI vs Durvalumab and Observation in Radically Treated Patients With Stage III NSCLC

Recruiting

170

Europe

Durvalumab, Imfinzi, low-dose PCI, Prophylactic Cranial Irradiation (PCI)

Association NVALT Studies

Carcinoma, Non-Small-Cell Lung

12/28

12/32

Maaskant

LORD, NCT02492607: Management of Low-risk (Grade I and II) DCIS

Recruiting

N/A

2500

Europe

Standard treatment, digital mammography, Active surveillance, radiotherapy

The Netherlands Cancer Institute, Borstkanker Onderzoek Groep, European Organisation for Research and Treatment of Cancer - EORTC

DCIS

02/34

Levin

MajesTEC-4, NCT05243797 / 2021-002531-27: Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

Recruiting

1572

Europe, Canada, RoW

Teclistamab, JNJ-64007957, Lenalidomide

Stichting European Myeloma Network, Janssen Pharmaceutica

Multiple Myeloma

04/28

04/32

Simkens, Lieke HJ

CRITICS-II, NCT02931890 / 2015-004627-31: Multicentric Randomised Trial for Resectable Gastric Cancer

Active, not recruiting

207

Europe

Docetaxel, Taxotere, Oxaliplatin, Eloxatin, Capecitabine, Xeloda, gastrectomy, radiotherapy of gastric cancer, Paclitaxel, Carboplatin

The Netherlands Cancer Institute

Gastric Cancer

04/25

03/29

Mekenkamp, L

GIMICC, NCT03941080: Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer

Recruiting

N/A

300

Europe

fecal sample, questionnaire, Blood sample

University Medical Center Groningen

Colorectal Cancer Metastatic

01/25

PLCRC, NCT02070146: Prospective Data Collection Initiative on Colorectal Cancer

Recruiting

N/A

50000

Europe

Dutch Colorectal Cancer Group

Colorectal Cancer

01/50

01/51

Westgeest, H

DRUP, NCT02925234 / 2015-004398-33: The Drug Rediscovery Protocol ( Trial)

Recruiting

1550

Europe

Cancer, Tumors, Neoplasm, Neoplasia

09/27

12/27

PRO-RCC, NCT05326620: National PROspective Infrastructure for Renal Cell Carcinoma

Recruiting

N/A

2000

Europe

PROspective Renal Cancer Cohort Foundation, Comprehensive Cancer Centre The Netherlands, Merck Sharp & Dohme LLC, Bristol-Myers Squibb, Ipsen

Renal Cancer, Renal Cell Carcinoma, Renal Cell Cancer Metastatic

01/30

Bosch, A

LORD, NCT02492607: Management of Low-risk (Grade I and II) DCIS

Recruiting

N/A

2500

Europe

Standard treatment, digital mammography, Active surveillance, radiotherapy

The Netherlands Cancer Institute, Borstkanker Onderzoek Groep, European Organisation for Research and Treatment of Cancer - EORTC

DCIS

02/34

Leqlercq, Wouter KG

DRAGON 2, NCT05428735: The Trial

Recruiting

N/A

348

Europe, Canada, US, RoW

Embolization

Maastricht University

Colorectal Cancer Liver Metastases (CRLM), Small Future Liver Remnant (FLR)

06/26

06/29

Leclercq, Wouter

DRAGON 2, NCT05428735: The Trial

Recruiting

N/A

348

Europe, Canada, US, RoW

Embolization

Maastricht University

Colorectal Cancer Liver Metastases (CRLM), Small Future Liver Remnant (FLR)

06/26

06/29

Besselaar, A

CURVE, NCT05379127: Comparing Use of Radiographs Versus Patient Empowerment

Recruiting

N/A

812

Europe

Patient-empowered follow up, Standard follow-up

Radboud University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development, Trialbureau Zorgevaluatie Nederland, Nederlandse Orthopaedische Vereniging, Vereniging Scoliose Patiënten, Dutch Adolescent Idiopathic Scoliosis (AIS) Consortium

Adolescent Idiopathic Scoliosis

12/25

Dercksen, Wouter

SAUNA, NCT05701241: Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients

Recruiting

270

Europe

Somatostatin analog, lanreotide, octreotide, sandostatin, somatuline

University Hospital, Antwerp, Erasmus Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development, Belgium Health Care Knowledge Centre

Gastroenteropancreatic Neuroendocrine Tumor

04/29

04/34

Eijsbouts

PREVAIL, NCT05202509 / 2021-005092-39: Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease

Active, not recruiting

9541

Europe, Canada, Japan, US, RoW

Obicetrapib, Placebo

NewAmsterdam Pharma, Monash University

Atherosclerotic Cardiovascular Disease

11/26

Osinski, Aart

Wean-Trach, NCT05906888: Weaning with Tracheostomy - an Observational Study on Patient-centered Outcomes

Recruiting

N/A

150

Europe

Henrik Endeman, Franciscus &Vlietland

Weaning Failure, Mechanical Ventilation, Patient-centered Care

11/24

12/24

Lominashvili, Nanuli

PREVAIL, NCT05202509 / 2021-005092-39: Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease

Active, not recruiting

9541

Europe, Canada, Japan, US, RoW

Obicetrapib, Placebo

NewAmsterdam Pharma, Monash University

Atherosclerotic Cardiovascular Disease

11/26



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