| Jyrkkiö, Sirkku |
POLAR BEAR, NCT04332822 / 2018-003889-14: A Randomized, Multicenter, Phase III Trial Comparing Treatment With R-mini-CHOP With R-mini-CHP + Polatuzumab Vedotin in Patients With Diffuse Large Cell B Cell Lymphoma |
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| Recruiting | 3 | 300 | Europe, RoW | R-pola-mini-CHP, R-mini-CHOP | Nordic Lymphoma Group, Roche Pharma AG | DLBCL, Diffuse Large B Cell Lymphoma | 12/25 | 12/28 | | |
| Active, not recruiting | 2 | 120 | Europe | R-CHOEP, DA-EPOCH-R | Nordic Lymphoma Group, Helsinki University Central Hospital, Aarhus University Hospital | Lymphoma, Large B-Cell, Diffuse | 01/21 | 12/24 | | |
| Recruiting | N/A | 8 | Europe | Positron emission tomography (PET) imaging at rest and during supine bicycle exercise | Turku University Hospital | Tumor Blood Flow at Rest and During Exercise | 08/24 | 08/24 | | |
| Knuuti, Juhani |
| Active, not recruiting | N/A | 930 | Europe | | Precordior Ltd | Coronary Artery Disease | 12/21 | 12/23 | | |
| Recruiting | N/A | 60 | Europe | 68Ga-NODAGA-RGD PET-imaging | Turku University Hospital, University of Lausanne Hospitals, Leiden University Medical Center | Coronary Artery Disease | 12/23 | 12/23 | | |
| Recruiting | N/A | 300 | Europe | | Turku University Hospital | Coronary Artery Disease | 08/25 | 08/25 | | |
| Rinne, Juha |
| Terminated | 3 | 1027 | Europe, Canada, Japan, US, RoW | Aducanumab, BIIB037, Aducanumab-avwa, Aduhelm, Placebo | Biogen, Biogen Idec Research Limited | Alzheimer's Disease | 08/24 | 08/24 | | |
| Recruiting | 2 | 282 | Europe, Canada, US, RoW | GSK4527226, Placebo | GlaxoSmithKline, Alector Inc. | Alzheimer's Disease | 12/26 | 02/29 | | |
CELIA, NCT05399888: A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age |
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| Active, not recruiting | 2 | 416 | Europe, Canada, Japan, US, RoW | BIIB080, ISIS 814907, BIIB080-matching placebo | Biogen | Mild Cognitive Impairment Due to Alzheimer's Disease, Alzheimer's Disease Dementia | 05/26 | 01/29 | | |
NCT05328115: A Study on the Safety, Tolerability and Immunogenicity of ALZ-101 in Participants With Early Alzheimer's Disease |
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| Recruiting | 1 | 33 | Europe | ALZ-101, Placebo | Alzinova AB, CRST Oy | Alzheimer Disease, Dementia Alzheimers, Dementia, Mild | 01/25 | 01/25 | | |
NCT06659562: Clinical Study of HER-096 in Healthy Volunteer Subjects and Patients with Parkinson's Disease |
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| Recruiting | 1 | 40 | Europe | HER-096, Placebo, Sodium chloride 9 mg/ml, 0.9% physiological saline solution | Herantis Pharma Plc., Clinical Research Services Turku - CRST Ltd, BC Platforms, Oy Medfiles Ltd | Parkinson Disease, Idiopathic | 09/25 | 12/25 | | |
| Recruiting | N/A | 1062 | Europe | ICG fluorescence imaging | Oulu University Hospital, University of Oulu, Central Finland Hospital District, Tampere University Hospital, Turku University Hospital, Hospital District of Helsinki and Uusimaa, Päijänne Tavastia Central Hospital, Seinäjoki Central Hospital, Seinäjoki, Finland | Colorectal Cancer, Colorectal Neoplasms, Gastrointestinal Cancer, Gastrointestinal Neoplasms, Diverticulosis, Colonic, Gastrointestinal Disease | 07/23 | 12/23 | | |
NCT04996511: Day Case Colectomy: Optimizing Short Stay-surgery. |
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| Recruiting | N/A | 10 | Europe | PulseOn, Faros, Emfit QS | Joint Authority for Päijät-Häme Social and Health Care, Tampere University | Monitoring, Physiologic | 05/26 | 12/26 | | |
| Recruiting | N/A | 40 | Europe | FDG-PET study | Turku University Hospital | Alzheimer Disease, Mild Cognitive Impairment, Positron Emission Tomography | 10/25 | 10/25 | | |
| Minn, Heikki RI |
| Not yet recruiting | N/A | 30 | Europe | Liquid biopsy | Turku University Hospital | Head and Neck Squamous Cell Carcinoma | 06/22 | 12/22 | | |
FURTHER, NCT04307914: Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases |
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| Recruiting | N/A | 216 | Europe | External beam radiotherapy, MR-HIFU, MRgFUS, MR guided High Intensity Focused Ultrasound | UMC Utrecht, Turku University Hospital, Universitätsklinikum Köln, University of Roma La Sapienza, Istituto Ortopedico Rizzoli, University of Bologna, Isala | Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer, Pain, Cancer Induced Bone Pain, Quality of Life, Tumor, Neoplasm Metastasis | 01/26 | 06/26 | | |
| Recruiting | N/A | 8 | Europe | Positron emission tomography (PET) imaging at rest and during supine bicycle exercise | Turku University Hospital | Tumor Blood Flow at Rest and During Exercise | 08/24 | 08/24 | | |
| Nuutila, Pirjo |
| Recruiting | 4 | 60 | Europe | Movies, Cold, Hyperinsulinemic euglycemic clamp, H2[15O]O PET/CT, [18F]FDG PET/CT, CEUS or Contrast enhanced Ultrasound | Turku University Hospital | Obesity and Overweight | 12/24 | 12/24 | | |
BariBrainPET, NCT05080205: Effects of Morbid Obesity and Bariatric Surgery on Brain Inflammation, Insulin Resistance and Central Reward System |
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| Active, not recruiting | N/A | 30 | Europe | Bariatric surgery, Roux-en-Y gastric bypass, Sleeve gastrectomy | Turku University Hospital | Obesity, Morbid, Insulin Resistance | 10/21 | 12/22 | | |
AM05, NCT05132335: A Repeatability Study of Fatty Acid Uptake Using PET/MR Imaging in Patients With T2DM and Non-diabetic Control Subjects |
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| Completed | N/A | 19 | Europe | Imaging Biomarkers, Assessment of repeatability of fatty acid uptake in adipose using PETMRI | Turku University Hospital, Antaros Medical | Diabetes Mellitus, Type 2 | 11/21 | 04/22 | | |
| Recruiting | N/A | 500 | Europe | MRI (magnetic resonance imaging), US (ultrasound), Sonography, Renal Biopsy, Kidney biopsy, percutaneous renal biopsy, Positron Emission Tomography (PET), PET scan, Microvascular Assessment | University of Leeds, University of Exeter, University Hospital, Bordeaux, University of Bari, University of Turku, Lund University, Swiss Institute of Bioinformatics | Diabetic Kidney Disease | 09/22 | 09/38 | | |
BARIBRAIN, NCT04343469: Effects of Morbid Obesity and Bariatric Surgery on Brain Inflammation, and Activation of Central Reward System |
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| Active, not recruiting | N/A | 90 | Europe | Bariatric Surgery (RYGB or LSG) | Turku University Hospital | Morbid Obesity | 09/22 | 09/22 | | |
NCT03106688: Neuromolecular Risk Factors for Obesity (PROSPECT) |
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| Active, not recruiting | N/A | 60 | Europe | fMRI imaging, [11C]carfentanil PET scan, [18F]FMPEP-d2 PET scan, [18F]-FDG PET scan, Physical activity measures and fitness tests, Laboratory measurements, Questionnaires, Hyperinsulinemic euglycemic clamp | Turku University Hospital | Obesity | 12/22 | 12/22 | | |
NCT03310502: Variation of Genes Controlling Carbohydrate and Lipid Metabolism |
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| Recruiting | N/A | 2050 | Europe | | Turku University Hospital, University of Eastern Finland, Kuopio University Hospital, University of Turku | Diabetes Mellitus, Type 2, Cardiovascular Diseases, Obesity, Insulin Resistance, Lipid Metabolism Disorders, PreDiabetes | 12/22 | 12/24 | | |
VAP-PET, NCT06555042: Investigation of VAP-1 Expression and Tissue Blood Flow by PET-MRI in Patients With Crohn's Disease |
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| Recruiting | N/A | 20 | Europe | | Turku University Hospital, University of Turku | Crohn Disease, Inflammatory Bowel Diseases, Crohn Disease of Small Intestine, Crohn Colitis, Crohn's Ileocolitis, Crohn Disease in Remission | 01/26 | 06/26 | | |
| Recruiting | N/A | 40 | Europe | FDG-PET study | Turku University Hospital | Alzheimer Disease, Mild Cognitive Impairment, Positron Emission Tomography | 10/25 | 10/25 | | |
AVAIN, NCT05101538: Anorexia Nervosa and Its Effects on Brain Function, Body Metabolism and Their Interaction |
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| Completed | N/A | 25 | Europe | | Turku University Hospital | Anorexia Nervosa | 11/24 | 11/24 | | |
| Koffert, Jukka P |
VAP-PET, NCT06555042: Investigation of VAP-1 Expression and Tissue Blood Flow by PET-MRI in Patients With Crohn's Disease |
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| Recruiting | N/A | 20 | Europe | | Turku University Hospital, University of Turku | Crohn Disease, Inflammatory Bowel Diseases, Crohn Disease of Small Intestine, Crohn Colitis, Crohn's Ileocolitis, Crohn Disease in Remission | 01/26 | 06/26 | | |
| Monfort-Pires, Milena |
NCT04385615: Fasting Mimicking Diet and Beige/Brown Adipose Tissue in Humans |
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| Not yet recruiting | N/A | 26 | RoW | Fasting Mimicking Diet | University of Campinas, Brazil | Obesity | 07/21 | 07/22 | | |
| Recruiting | N/A | 30 | Europe | Non-palatable meal, low-hedonic reward, Palatable meal, high-hedonic reward | Turku University Hospital, University of Turku | Obesity | 06/25 | 06/26 | | |
| Airas, Laura |
| Active, not recruiting | N/A | 35 | Europe | | Turku University Hospital | Multiple Sclerosis | 12/23 | 12/24 | | |
NCT05111678: Neurological Symptoms and Findings in Individuals Exposed to Indoor Air Pollutants |
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| Completed | N/A | 35 | Europe | | Turku University Hospital | Exposure to Polluted Air | 12/23 | 03/24 | | |
| Active, not recruiting | N/A | 40 | Europe | | Turku University Hospital | Multiple Sclerosis | 12/25 | 12/25 | | |
| Active, not recruiting | N/A | 15 | Europe | Imaging | Turku University Hospital | Multiple Sclerosis | 02/24 | 12/25 | | |
TERIPET, NCT03368677: Effect of Teriflunomide Treatment on Microglial Activation in an MS Patient Cohort at Risk of Progression |
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| Active, not recruiting | N/A | 26 | Europe | | Turku University Hospital | Multiple Sclerosis | 12/24 | 12/24 | | |
| Enrolling by invitation | N/A | 15 | Europe | | Turku University Hospital | Multiple Sclerosis | 06/28 | 12/28 | | |
FUP-MS, NCT04625049: Does Microglial Activation Promote Lesion Growth and Progression Among Multiple Sclerosis Patients |
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| Enrolling by invitation | N/A | 100 | Europe | | Turku University Hospital | Multiple Sclerosis | 11/30 | 11/31 | | |
| Acosta, Francisco |
MOTORBAT, NCT05468151: Cold Acclimation as a Modulator of Brown Adipose Tissue Function in Adults With Obesity |
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| Recruiting | N/A | 45 | Europe | Cold acclimation, Cold immersion, Intervention Control group - volunteers with obesity, Acute cold exposure | Turku University Hospital, University of Turku, University of Barcelona, University of Ottawa | Obesity | 07/24 | 09/25 | | |
| Heinonen, Ilkka H |
GLYMREG, NCT04255758: Acute Effects of Vigorous-intensity Aerobic Exercise on Glymphatic Flow in Healthy Adults |
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| Recruiting | N/A | 20 | Europe | Cycle Ergometer Exercise | Turku University Hospital | Glymphatic System, Neurodegeneration | 12/21 | 12/21 | | |
| Recruiting | N/A | 20 | Europe | Acute exercise | Turku University Hospital | Cardiac Function | 12/21 | 12/21 | | |
| Recruiting | N/A | 28 | Europe | Exercise | Turku University Hospital | Tumor | 12/22 | 12/22 | | |
| Recruiting | N/A | 8 | Europe | Positron emission tomography (PET) imaging at rest and during supine bicycle exercise | Turku University Hospital | Tumor Blood Flow at Rest and During Exercise | 08/24 | 08/24 | | |
| Recruiting | N/A | 20 | Europe | Exercise | Turku University Hospital | Cancer, Breast | 12/24 | 12/24 | | |
| Virtanen, Kirsi A |
| Recruiting | N/A | 30 | Europe | Non-palatable meal, low-hedonic reward, Palatable meal, high-hedonic reward | Turku University Hospital, University of Turku | Obesity | 06/25 | 06/26 | | |
MOTORBAT, NCT05468151: Cold Acclimation as a Modulator of Brown Adipose Tissue Function in Adults With Obesity |
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| Recruiting | N/A | 45 | Europe | Cold acclimation, Cold immersion, Intervention Control group - volunteers with obesity, Acute cold exposure | Turku University Hospital, University of Turku, University of Barcelona, University of Ottawa | Obesity | 07/24 | 09/25 | | |
BATNAD, NCT06627868: Nicotinamide Adenine Dinucleotide (NAD+) Metabolism in Human Brown Adipose Tissue |
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| Not yet recruiting | N/A | 68 | Europe | NAD+ precursor, Placebo | University of Turku | Obesity, Abdominal | 08/27 | 08/27 | | |
| Kemppainen, Jukka |
| Recruiting | N/A | 35 | Europe | GnRH antagonist, Degarelix | Turku University Hospital | Prostate Cancer | 09/21 | 03/23 | | |
HENEPET, NCT04196985: 18F-FDG PET/CT Versus 18F-FDG PET/MRI in Detecting Locoregional Recurrence 3 Months After CRT in Head and Neck SCC |
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| Recruiting | N/A | 40 | Europe | PET/MRI, PET/CT | Turku University Hospital | Head and Neck Squamous Cell Carcinoma | 10/22 | 10/24 | | |
| Malaspina, Simona |
| Recruiting | N/A | 35 | Europe | GnRH antagonist, Degarelix | Turku University Hospital | Prostate Cancer | 09/21 | 03/23 | | |
HENEPET, NCT04196985: 18F-FDG PET/CT Versus 18F-FDG PET/MRI in Detecting Locoregional Recurrence 3 Months After CRT in Head and Neck SCC |
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| Recruiting | N/A | 40 | Europe | PET/MRI, PET/CT | Turku University Hospital | Head and Neck Squamous Cell Carcinoma | 10/22 | 10/24 | | |
| Nystrand, Ilja |
| Recruiting | N/A | 8 | Europe | Positron emission tomography (PET) imaging at rest and during supine bicycle exercise | Turku University Hospital | Tumor Blood Flow at Rest and During Exercise | 08/24 | 08/24 | | |
| Kalliokoski, Kari K |
VAP-PET, NCT06555042: Investigation of VAP-1 Expression and Tissue Blood Flow by PET-MRI in Patients With Crohn's Disease |
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| Recruiting | N/A | 20 | Europe | | Turku University Hospital, University of Turku | Crohn Disease, Inflammatory Bowel Diseases, Crohn Disease of Small Intestine, Crohn Colitis, Crohn's Ileocolitis, Crohn Disease in Remission | 01/26 | 06/26 | | |
| Parkkola, Riitta |
NCT05648812: Neonatal Brain Ultrasound With CEUS and Elastography |
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| Recruiting | 3 | 100 | Europe | Brain contrast enhanced ultrasound, brain ultrasound elastography, Sulfur Hexafluoride, SonoVue | Turku University Hospital | Neonatal Hypoxic Ischemic Encephalopathy, Neonatal Stroke, Neonatal Encephalopathy, Unspecified | 07/29 | 12/29 | | |
NCT05694611: Preterm Neonates Brain Ultrasound With CEUS and Elastography |
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| Recruiting | 3 | 100 | Europe | Brain contrast enhanced ultrasound, brain ultrasound elastography, Sulfur Hexafluoride, SonoVue | Turku University Hospital | Prematurity | 07/29 | 12/29 | | |
| Recruiting | N/A | 20 | Europe | PET imaging, 18F-FDG, PET imaging, 68Ga-DOTANOC | Turku University Hospital, University of Turku | Intracranial Aneurysm, Cerebral Aneurysm, Inflammation | 01/22 | 10/22 | | |
| Kallio, Petri |
| Recruiting | N/A | 20 | Europe | Acute exercise | Turku University Hospital | Cardiac Function | 12/21 | 12/21 | | |
| Himanen, Sanna |
| Recruiting | 4 | 60 | Europe | Movies, Cold, Hyperinsulinemic euglycemic clamp, H2[15O]O PET/CT, [18F]FDG PET/CT, CEUS or Contrast enhanced Ultrasound | Turku University Hospital | Obesity and Overweight | 12/24 | 12/24 | | |
AVAIN, NCT05101538: Anorexia Nervosa and Its Effects on Brain Function, Body Metabolism and Their Interaction |
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| Completed | N/A | 25 | Europe | | Turku University Hospital | Anorexia Nervosa | 11/24 | 11/24 | | |
AVAIN_JR, NCT05357053: Anorexia Nervosa and Its Effects on Brain Function, Body Metabolism and Their Interaction in Adolescents |
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| Recruiting | N/A | 100 | Europe | | Turku University Hospital, University of Turku | Anorexia Nervosa | 12/24 | 12/27 | | |
| Karukivi, Max |
| Active, not recruiting | N/A | 124 | Europe | Intervention | Turku University Hospital, University of Turku, City of Turku | Depression, Anxiety, Emotional Stress | 06/22 | 12/23 | | |
NCT06606002: The Effectiveness of Group Schema Therapy in the Treatment of Borderline Symptoms in Adolescents |
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| Not yet recruiting | N/A | 64 | NA | Group schema therapy, Treatment as Usual (TAU) | Turku University Hospital, University of Turku | Borderline Symptoms, Borderline Personality Disorder | 12/27 | 12/29 | | |
AVAIN_JR, NCT05357053: Anorexia Nervosa and Its Effects on Brain Function, Body Metabolism and Their Interaction in Adolescents |
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| Recruiting | N/A | 100 | Europe | | Turku University Hospital, University of Turku | Anorexia Nervosa | 12/24 | 12/27 | | |
| U-Din, Mueez |
MOTORBAT, NCT05468151: Cold Acclimation as a Modulator of Brown Adipose Tissue Function in Adults With Obesity |
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| Recruiting | N/A | 45 | Europe | Cold acclimation, Cold immersion, Intervention Control group - volunteers with obesity, Acute cold exposure | Turku University Hospital, University of Turku, University of Barcelona, University of Ottawa | Obesity | 07/24 | 09/25 | | |
BATNAD, NCT06627868: Nicotinamide Adenine Dinucleotide (NAD+) Metabolism in Human Brown Adipose Tissue |
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| Not yet recruiting | N/A | 68 | Europe | NAD+ precursor, Placebo | University of Turku | Obesity, Abdominal | 08/27 | 08/27 | | |
| Ekblad, Laura |
| Recruiting | N/A | 40 | Europe | FDG-PET study | Turku University Hospital | Alzheimer Disease, Mild Cognitive Impairment, Positron Emission Tomography | 10/25 | 10/25 | | |
| Rebelos, Eleni |
| Recruiting | N/A | 40 | Europe | FDG-PET study | Turku University Hospital | Alzheimer Disease, Mild Cognitive Impairment, Positron Emission Tomography | 10/25 | 10/25 | | |
| Nummenmaa, Lauri |
| Recruiting | 4 | 60 | Europe | Movies, Cold, Hyperinsulinemic euglycemic clamp, H2[15O]O PET/CT, [18F]FDG PET/CT, CEUS or Contrast enhanced Ultrasound | Turku University Hospital | Obesity and Overweight | 12/24 | 12/24 | | |
