WakeMed Health and Hospitals
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 7 Trials 
22 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Russell, Stuart J
LUX-Dx TRENDS, NCT04790344: Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System.

Active, not recruiting
N/A
525
US
Investigational LUX-Dx ICM Implant
Boston Scientific Corporation
Heart Failure
05/26
06/26
England, Amanda
NCT04214834: Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

Active, not recruiting
3
190
US
Morphine, Methadone
Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Neonatal Opioid Withdrawal Syndrome
01/24
06/26
SIL02, NCT03142568: Safety of Sildenafil in Premature Infants

Recruiting
2
120
Canada, US
Sildenafil, Revatio, Placebo, sugar water
University of North Carolina, Chapel Hill, Duke University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), The Emmes Company, LLC
Bronchopulmonary Dysplasia
02/25
04/25
SILDI-SAFE, NCT04447989: Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia

Active, not recruiting
2
120
US
Sildenafil, Revatio, Placebo, Dextrose 5%
Christoph Hornik, University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI)
Bronchopulmonary Dysplasia of Newborn
12/24
01/25
POPS or POP02, NCT04278404: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Recruiting
N/A
5000
Canada, US
The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:, Aminocaproic acid, Amiodarone, Bosentan, Budesonide, Cefdinir, Cefepime, Ceftazidime, Clindamycin, Clobazam, Dexamethasone, Dexmedetomidine, Dextroamphetamine/Amphetamine, Fosfomycin, Furosemide, Gabapentin, Guanfacine, Hydrocortisone, Labetalol, Meropenem, Metformin, Milrinone, Nalbuphine, Nicardipine, Nifedipine, Oseltamivir, Oxycodone, Risperidone, Sertraline, Sevelamer Carbonate / Sevelamer Hydrochloride, Spironolactone, Terbutaline, Tranexamic acid, Voriconazole, Zolpidem, Azithromycin, Lopinavir/Ritonavir, Ribavirin, Tocilizumab, Anakinra, Aspirin, Canakinumab, Colchicine, Interferon, Remdesivir, Ruxolitinib, Sarilumab, Abatacept, Infliximab
Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
09/26
09/27
Norton, Rhonda
CAMP POAF, NCT05681182: Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone

Completed
4
30
US
CardiaMend with the Addition of Amiodarone
WakeMed Health and Hospitals, Helios Cardio Inc
Post Operative Atrial Fibrillation
02/24
02/24
PACES, NCT04045665 / 2021-005022-18: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Recruiting
3
3200
Europe, Canada, US
Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center
Atrial Fibrillation, Stroke, Bleeding
06/25
06/25
NCT05614869: Continuous Treatment With PREVENA Therapy for 14 Days

Recruiting
N/A
353
US
Prevena Plus Incision Management System with Prevena Dressings
KCI USA, Inc, Solventum US LLC, 3M
Abdominal Surgery, Orthopedic Surgery, Cardiovascular Surgery, Vascular Surgery
03/27
05/27
LeAAPS, NCT05478304: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

Recruiting
N/A
6500
Europe, Canada, US
AtriClip LAA Exclusion System
AtriCure, Inc., Population Health Research Institute
Ischemic Stroke, Systemic Embolism
12/31
04/32
Daniel, LaMonica
CAMP POAF, NCT05681182: Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone

Completed
4
30
US
CardiaMend with the Addition of Amiodarone
WakeMed Health and Hospitals, Helios Cardio Inc
Post Operative Atrial Fibrillation
02/24
02/24
CHANGE AFIB, NCT05130268: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation

Completed
4
339
US
Dronedarone, Multaq
American Heart Association, Duke Clinical Research Institute, Sanofi
Atrial Fibrillation
01/24
06/24
Gen3, NCT04615858: Genepro Generation 3 Protein Bioavailability Compared to Whey Protein

Recruiting
N/A
40
US
Genepro Generation 3 Protein, Whey Protein
Musclegen Research, Inc., WakeMed Bariatric Surgery & Weight Loss Center
Absorption; Disorder, Protein, Protein Malabsorption, Protein Intolerance
01/21
02/21
NCT06740266: The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families

Recruiting
N/A
250
US
Promoting First Relationships in Primary Care (PFR-PC)
University of Washington, WakeMed Health and Hospitals, National Institute of Nursing Research (NINR)
Parent Child Relationship, Child Social-Emotional Development, Telomere Length, Epigenetic Aging
05/28
04/29
Williams, Judson
CAMP POAF, NCT05681182: Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone

Completed
4
30
US
CardiaMend with the Addition of Amiodarone
WakeMed Health and Hospitals, Helios Cardio Inc
Post Operative Atrial Fibrillation
02/24
02/24
PACES, NCT04045665 / 2021-005022-18: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Recruiting
3
3200
Europe, Canada, US
Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center
Atrial Fibrillation, Stroke, Bleeding
06/25
06/25
LeAAPS, NCT05478304: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

Recruiting
N/A
6500
Europe, Canada, US
AtriClip LAA Exclusion System
AtriCure, Inc., Population Health Research Institute
Ischemic Stroke, Systemic Embolism
12/31
04/32
White, Donna
ART_CIN_II, NCT04098744: Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)

Recruiting
2
78
US
Artesunate vaginal insert, Artesunic acid, DHA, artemisinin, Placebo vaginal insert
Frantz Viral Therapeutics, LLC, Amarex Clinical Research, M.D. Anderson Cancer Center, Harris Health System (L.B.J. Hospital), The Cleveland Clinic, University of Michigan, Morehouse School of Medicine
CIN 2/3, HPV Infection, Pre-Cancerous Dysplasia, Cervical Dysplasia, HPV Related Disease
07/25
12/25
ART-VIN IIB, NCT06075264: Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)

Recruiting
2
27
US
Artesunate ointment, Artesunic acid, Dihydroartemisinin (DHA), Artemisinin, Placebo ointment, Placebo to artesunate ointment
Frantz Viral Therapeutics, LLC, The Cleveland Clinic
Vulvar Diseases, HPV Infection, Vulvar HSIL, Pre-Cancerous Dysplasia, HPV Disease, VIN, Usual Type, VIN 2 of Usual Type, VIN 3 of Usual Type, Vin II, Vin III, VIN Grade 2, VIN Grade 3, High Grade Intraepithelial Neoplasia
12/25
12/26
ENGOT-ov60, NCT04625270 / 2020-004264-26: A Study of Avutometinib (VS-6766) V. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer with and Without a KRAS Mutation

Active, not recruiting
2
225
Europe, Canada, US
avutometinib (VS-6766), avutometinib (VS-6766) and defactinib, avutometinib (VS-6766) and VS-6063
Verastem, Inc., European Network of Gynaecological Oncological Trial Groups (ENGOT), GOG Foundation
Low Grade Ovarian Serous Adenocarcinoma, Ovarian Cancer
11/24
12/26
Mitin, Natalia
NCT03635606: GUARD-AKI: Validation of AKI-Sapere in Cardiac Surgery Patients

Completed
N/A
370
US
Sapere Bio, WakeMed Health and Hospitals, Johns Hopkins University, Hoag Memorial Hospital Presbyterian
Coronary Artery Disease
09/22
02/23
SENSE, NCT04932031: Risk Prediction of Taxane Chemotherapy-Induced Peripheral Neuropathy

Terminated
N/A
123
US
Sapere Bio, National Institute on Aging (NIA), University of North Carolina, University of Alabama at Birmingham
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Aging
11/23
11/23
Neff, Janice
NCT06112626: Chlorhexidine Gluconate Bathing Education Video Among Hospitalized Patients

Recruiting
N/A
1000
US
CHG Skin Treatment Video
Duke University, Massachusetts General Hospital, Indiana University Health
Infections
09/25
12/25

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