| Smith, Robert C |
| Active, not recruiting | 1/2 | 200 | Europe, US | HB-201 intravenous administration., HB-202 intravenous administration alternating with HB-201 intravenous administration., HB-201 intravenous administration + standard of care regimen including pembrolizumab., HB-202 / HB-201 alternating intravenous administration + pembrolizumab., HB-202 / HB-201 alternating intravenous administration + standard of care regimen including pembrolizumab., HB-201 or HB-201/HB-202 alternating treatment using CD8 PET Tracer (Zr-Df-IAB22M2C) | Hookipa Biotech GmbH, Hookipa Biotech | HPV-Related Squamous Cell Carcinoma | 06/25 | 06/26 | | |
| Recruiting | N/A | 585 | US | NeoChord DS1000, Surgical Mitral Valve Repair | NeoChord | Mitral Valve Insufficiency | 07/22 | 07/27 | | |
SITRAL, NCT02830204: Surgical Implantation of TRAnscatheter vaLve in Native Mitral Annular Calcification () Study |
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| Completed | N/A | 25 | US | Mitral Valve Replacement with Sapien3, MVR | Baylor Research Institute, Edwards Lifesciences | Mitral Annular Calcification | 01/23 | 09/23 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN |
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| Recruiting | N/A | 1400 | Europe, US, RoW | Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation | Medtronic Vascular | Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus | 11/26 | 11/29 | | |
INTERMENTAL, NCT05118828: Guided Internet-based Interventions in Primary Care Effectiveness-implementation Randomized Controlled Trial |
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| Active, not recruiting | N/A | 1000 | Europe | Guided internet-based cognitive behavioural therapy, Treatment as usual in Prompt Mental Health Care (TAU-PMHC) | Norwegian Institute of Public Health, Norwegian Directorate of Health, University of Bergen, Göteborg University, University of Tromso, Sussex Partnership NHS Foundation Trust | Anxiety, Mild to Moderate Depression | 08/24 | 06/26 | | |
Reshape-HF2, NCT02444338: A Clinical Evaluation of the Safety and Effectiveness of the MitraClip System in the Treatment of Clinically Significant Functional Mitral Regurgitation |
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| Completed | N/A | 505 | Europe, RoW | MitraClip, standard of care | University Medical Center Goettingen, University Medical Center Goettingen | Mitral Valve Insufficiency | 04/24 | 04/24 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
| Not yet recruiting | N/A | 50 | US | Transcatheter Tricuspid Valve Replacement, inQB8 MonarQ Transcatheter Tricuspid Valve Replacement System | inQB8 Medical Technologies, LLC | Tricuspid Valve Regurgitation | 10/26 | 10/29 | | |
| Not yet recruiting | N/A | 10 | US | Implant an epicardial device to reshape the mitral valve annulus | Mitre Medical Corp., BSWRI Cardiac Imaging Core Lab (CICL) | Ischemic Mitral Regurgitation, Functional Mitral Regurgitation | 12/24 | 12/27 | | |
NCT03382457: Clinical Study of Edwards Cardioband FIT Valve Repair System |
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| Recruiting | N/A | 55 | US | Transcatheter Tricuspid Valve Repair, Edwards Cardioband Tricuspid Valve Repair | Edwards Lifesciences | Tricuspid Regurgitation | 12/26 | 12/31 | | |
| Not yet recruiting | N/A | 150 | Europe | Aortic valve replacement | Barts & The London NHS Trust, University College, London | Aortic Valve Disease, Surgery--Complications, Immune System Disorder | 09/25 | 09/26 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
| Wong, Tom |
| Recruiting | N/A | 330 | Europe | Pre-implantation planning, ECGI mapping, Post-implantation assessment | EP Solutions SA | Heart Failure With Reduced Ejection Fraction | 09/25 | 06/26 | | |
DISCOVER, NCT03893331: AcQMap® Global Registry of Procedural and Long-term Clinical Outcomes (AcQMap Registry) |
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| Terminated | N/A | 479 | Europe | AcQMap System | Acutus Medical | Ablation of Arrhythmia's | 11/23 | 11/23 | | |
| Chan, Carmen |
NCT06673316: Integrating Design Thinking Into Undergraduate Nursing Education |
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| Recruiting | N/A | 50 | RoW | Design thinking workshop | Chinese University of Hong Kong | Nurse Training | 05/25 | 05/25 | | |
