Toronto General Hospital (University Health Network)
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 8 Trials 
15 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Sapisochin, Gonzalo
NEOLANGIO, NCT06569225: Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig in Resectable iCCA

Not yet recruiting
2
40
Canada
Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig
University Health Network, Toronto, Sunnybrook Health Sciences Centre, Hamilton Health Sciences Corporation
Cholangiocarcinoma Resectable
12/27
12/28
NEOTOMA, NCT05440864: Durvalumab and Tremelimumab in Resectable HCC

Recruiting
2
28
Europe, Canada
Tremelimumab, Durvalumab
University Health Network, Toronto, Clinica Universidad de Navarra, Universidad de Navarra, University of Milan
Hepatocellular Carcinoma
11/25
11/26
LT for iCCA, NCT02878473: Liver Transplantation for Early Intrahepatic Cholangiocarcinoma

Terminated
2
2
Canada
Deceased donor Liver Transplantation
University Health Network, Toronto
Intrahepatic Cholangiocarcinoma
12/24
12/24
MacroTrans, NCT06725121: Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant

Recruiting
1/2
48
Canada
Atezolizumab & Bevacizumab, AtezoBev, AVASTIN, TECENTRIQ, Yttrium-90 (Y-90), YTTRIGA, Stereotactic body radiotherapy (SBRT)
University Health Network, Toronto
Hepatocellular Carcinoma (HCC), Macrovascular Invasion, Liver Transplant Surgery, Downstaging
06/31
06/34
NCT03396016: Plasmatic Factor V as a Predictor of Graft Dysfunction After Liver Transplantation

Active, not recruiting
N/A
140
Canada
University Health Network, Toronto
Liver Transplant Failure
04/21
02/23
SOLT, NCT05612477: Blood Salvage in Orthotopic Liver Transplantation With HCC

Enrolling by invitation
N/A
30
Canada
Autotransfusion
University Health Network, Toronto
Hepatocellular Carcinoma, Surgery
12/24
12/34
NCT02864485: Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases

Recruiting
N/A
20
Canada
live donor liver transplantation
University Health Network, Toronto
Colorectal Cancer, Liver Metastases
12/25
12/30
NCT04195503: Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma

Enrolling by invitation
N/A
10
Canada
Liver Transplantation
University Health Network, Toronto
Cholangiocarcinoma, Intrahepatic
12/29
12/34
NCT05289609: Developing Prediction Models for Allograft Failure After Liver Transplantation

Not yet recruiting
N/A
5000
Europe, Canada, Japan, US, RoW
Liver Transplantation
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, University of California, Los Angeles, University Hospital Padova, Mayo Clinic, Hospital Italiano de Buenos Aires, Tokyo Women's Medical University, Hospital Universitario La Paz, First Affiliated Hospital, Sun Yat-Sen University, University of Roma La Sapienza, University of Massachusetts, Worcester, The Cleveland Clinic, Dr. Rela Institute & Medical Centre, University of Toronto, Universidade Federal do ParanĂ¡, Royal Infirmary of Edinburgh, Erasmus Medical Center
Liver Transplant Disorder
12/23
04/24
Fralick, Michael
CATCO, NCT04330690: Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial

Active, not recruiting
3
2900
Canada
Artesunate, Imatinib, Infliximab, Dexamethasone, LSALT Peptide
Sunnybrook Health Sciences Centre, AbbVie, Apotex Inc., World Health Organization, University of British Columbia, Arch Biopartners Inc.
COVID-19
03/24
05/24
COVID-PRONE, NCT04383613: Prone Positioning for Patients on General Medical Wards With COVID19

Active, not recruiting
N/A
340
Canada
Prone positioning
Unity Health Toronto, Sunnybrook Health Sciences Centre, Sinai Health System, Toronto General Hospital, University Health Network, Toronto, William Osler Health System
Covid-19, ARDS
06/21
06/21
NCT06537609: A Platform Trial for Gram Negative Bloodstream Infections

Recruiting
N/A
2500
Canada
De-escalation VS No De-escalation, Oral beta-lactams VS non beta-lactams, Central vascular catheter retention VS Central vascular catheter replacement, Cephalosporin VS Carbapenem for low risk AmpC organisms, Routine follow-up blood culture VS No routine follow-up blood culture
Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR)
Gram-negative Bacteremia
04/27
04/28
DaNGER, NCT05402579: Diabetic Ketoacidosis From New SGLT2i: Can Genomics Estimate Risk

Recruiting
N/A
200
Canada
Genomic analysis
Mount Sinai Hospital, Canada, Unity Health Toronto, University Health Network, Toronto, Sault Area Hospital
Diabetes Type 2, DKA, Diabetic Ketoacidosis
06/24
06/24

Completed
N/A
174
Canada
De-escalation VS No De-escalation, Oral beta-lactams VS non beta-lactams, Central vascular catheter retention VS Central vascular catheter replacement, Cephalosporin VS Carbapenem for low risk AmpC organisms, Routine follow-up blood culture VS No routine follow-up blood culture
Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR)
Gram-negative Bacteremia
07/24
08/24
A-DONUT, NCT06004739: Antibiotics for Delirium in Older Adults With No Clear Urinary Tract Infection

Recruiting
N/A
550
Canada, US
Start Antibiotics / Continue Antibiotics for treatment of bacteriuria, No Antibiotics for treatment of bacteriuria
Mount Sinai Hospital, Canada, Sault Area Hospital, Michael Garron Hospital, Unity Health Toronto, The Ottawa Hospital, Northwestern Memorial Hospital
Infectious Disease
09/27
09/27

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