Sapisochin, Gonzalo |
| Not yet recruiting | 2 | 40 | Canada | Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig | University Health Network, Toronto, Sunnybrook Health Sciences Centre, Hamilton Health Sciences Corporation | Cholangiocarcinoma Resectable | 12/27 | 12/28 | | |
| Recruiting | 2 | 28 | Europe, Canada | Tremelimumab, Durvalumab | University Health Network, Toronto, Clinica Universidad de Navarra, Universidad de Navarra, University of Milan | Hepatocellular Carcinoma | 11/25 | 11/26 | | |
| Terminated | 2 | 2 | Canada | Deceased donor Liver Transplantation | University Health Network, Toronto | Intrahepatic Cholangiocarcinoma | 12/24 | 12/24 | | |
| Recruiting | 1/2 | 48 | Canada | Atezolizumab & Bevacizumab, AtezoBev, AVASTIN, TECENTRIQ, Yttrium-90 (Y-90), YTTRIGA, Stereotactic body radiotherapy (SBRT) | University Health Network, Toronto | Hepatocellular Carcinoma (HCC), Macrovascular Invasion, Liver Transplant Surgery, Downstaging | 06/31 | 06/34 | | |
NCT03396016: Plasmatic Factor V as a Predictor of Graft Dysfunction After Liver Transplantation |
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| Active, not recruiting | N/A | 140 | Canada | | University Health Network, Toronto | Liver Transplant Failure | 04/21 | 02/23 | | |
| Enrolling by invitation | N/A | 30 | Canada | Autotransfusion | University Health Network, Toronto | Hepatocellular Carcinoma, Surgery | 12/24 | 12/34 | | |
NCT02864485: Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases |
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| Recruiting | N/A | 20 | Canada | live donor liver transplantation | University Health Network, Toronto | Colorectal Cancer, Liver Metastases | 12/25 | 12/30 | | |
NCT04195503: Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma |
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| Enrolling by invitation | N/A | 10 | Canada | Liver Transplantation | University Health Network, Toronto | Cholangiocarcinoma, Intrahepatic | 12/29 | 12/34 | | |
NCT05289609: Developing Prediction Models for Allograft Failure After Liver Transplantation |
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| Not yet recruiting | N/A | 5000 | Europe, Canada, Japan, US, RoW | Liver Transplantation | Fondazione Policlinico Universitario Agostino Gemelli IRCCS, University of California, Los Angeles, University Hospital Padova, Mayo Clinic, Hospital Italiano de Buenos Aires, Tokyo Women's Medical University, Hospital Universitario La Paz, First Affiliated Hospital, Sun Yat-Sen University, University of Roma La Sapienza, University of Massachusetts, Worcester, The Cleveland Clinic, Dr. Rela Institute & Medical Centre, University of Toronto, Universidade Federal do ParanĂ¡, Royal Infirmary of Edinburgh, Erasmus Medical Center | Liver Transplant Disorder | 12/23 | 04/24 | | |
Fralick, Michael |
| Active, not recruiting | 3 | 2900 | Canada | Artesunate, Imatinib, Infliximab, Dexamethasone, LSALT Peptide | Sunnybrook Health Sciences Centre, AbbVie, Apotex Inc., World Health Organization, University of British Columbia, Arch Biopartners Inc. | COVID-19 | 03/24 | 05/24 | | |
| Active, not recruiting | N/A | 340 | Canada | Prone positioning | Unity Health Toronto, Sunnybrook Health Sciences Centre, Sinai Health System, Toronto General Hospital, University Health Network, Toronto, William Osler Health System | Covid-19, ARDS | 06/21 | 06/21 | | |
NCT06537609: A Platform Trial for Gram Negative Bloodstream Infections |
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| Recruiting | N/A | 2500 | Canada | De-escalation VS No De-escalation, Oral beta-lactams VS non beta-lactams, Central vascular catheter retention VS Central vascular catheter replacement, Cephalosporin VS Carbapenem for low risk AmpC organisms, Routine follow-up blood culture VS No routine follow-up blood culture | Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR) | Gram-negative Bacteremia | 04/27 | 04/28 | | |
| Recruiting | N/A | 200 | Canada | Genomic analysis | Mount Sinai Hospital, Canada, Unity Health Toronto, University Health Network, Toronto, Sault Area Hospital | Diabetes Type 2, DKA, Diabetic Ketoacidosis | 06/24 | 06/24 | | |
| Completed | N/A | 174 | Canada | De-escalation VS No De-escalation, Oral beta-lactams VS non beta-lactams, Central vascular catheter retention VS Central vascular catheter replacement, Cephalosporin VS Carbapenem for low risk AmpC organisms, Routine follow-up blood culture VS No routine follow-up blood culture | Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR) | Gram-negative Bacteremia | 07/24 | 08/24 | | |
| Recruiting | N/A | 550 | Canada, US | Start Antibiotics / Continue Antibiotics for treatment of bacteriuria, No Antibiotics for treatment of bacteriuria | Mount Sinai Hospital, Canada, Sault Area Hospital, Michael Garron Hospital, Unity Health Toronto, The Ottawa Hospital, Northwestern Memorial Hospital | Infectious Disease | 09/27 | 09/27 | | |