Texas Children's Hospital (Baylor College of Medicine)
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 10 Trials 
38 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Shneider, Benjamin
NCT02055768: Safety and Efficacy Study of the Intestinal Bile Acid Transport (IBAT) in the Reduction of Pruritus in ALGS

Not yet recruiting
2
24
US, Canada
LUM001 70 ug/kg/day, Intestinal Bile Acid Transport (IBAT) Inhibitor, Placebo, LUM001 140 ug/kg/day
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Lumena Pharmaceuticals, Inc.
Pruritus, Alagille Syndrome
02/15
05/15
NCT02922751: FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)

Completed
N/A
552
Canada, US
Liver Stiffness Measurement (LSM), FibroScan™
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia, Alagille Syndrome, Alpha1 Anti-Trypsin Deficiency, Portal Hypertension, Liver Fibrosis, Cholestasis
12/22
12/22
PROBE, NCT00061828: A Prospective Database of Infants With Cholestasis

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia, Neonatal Cholestasis
05/29
05/29
BASIC, NCT00345553: Biliary Atresia Study in Infants and Children

Recruiting
N/A
1265
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia
05/29
05/29
LOGIC, NCT00571272: Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis

Suspended
N/A
1675
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Liver Diseases, Alagille Syndrome, Alpha 1-Antitrypsin Deficiency
05/29
05/29
MITOHEP, NCT01148550: Longitudinal Study of Mitochondrial Hepatopathies

Suspended
N/A
67
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Michigan
Acute Liver Failure, Mitochondrial Diseases, End Stage Liver Disease, Respiratory Chain Deficiencies, Mitochondrial, Disorder of Fatty Acid Oxidation
05/29
05/29
NCT05272319: Genetic Collection Protocol

Recruiting
N/A
2230
Canada, US
Arbor Research Collaborative for Health
Liver Diseases
05/29
05/29
Hertel, Paula
NCT01774487: Pentoxifylline Therapy in Biliary Atresia

Terminated
2
17
US
Pentoxifylline, Trental
Baylor College of Medicine
Biliary Atresia
02/18
02/23
PROBE, NCT00061828: A Prospective Database of Infants With Cholestasis

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia, Neonatal Cholestasis
05/29
05/29
BASIC, NCT00345553: Biliary Atresia Study in Infants and Children

Recruiting
N/A
1265
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia
05/29
05/29
LOGIC, NCT00571272: Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis

Suspended
N/A
1675
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Liver Diseases, Alagille Syndrome, Alpha 1-Antitrypsin Deficiency
05/29
05/29
MITOHEP, NCT01148550: Longitudinal Study of Mitochondrial Hepatopathies

Suspended
N/A
67
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Michigan
Acute Liver Failure, Mitochondrial Diseases, End Stage Liver Disease, Respiratory Chain Deficiencies, Mitochondrial, Disorder of Fatty Acid Oxidation
05/29
05/29
NCT05272319: Genetic Collection Protocol

Recruiting
N/A
2230
Canada, US
Arbor Research Collaborative for Health
Liver Diseases
05/29
05/29
NCT04454463: Nonalcoholic Fatty Liver Disease (NAFLD) Database 3

Active, not recruiting
N/A
1640
US
Johns Hopkins Bloomberg School of Public Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Baylor College of Medicine, Case Western Reserve University, Duke University, Ann & Robert H Lurie Children's Hospital of Chicago, Indiana University, Liver Institute Northwest, Seattle Children's Hospital, St. Louis University, University of California, San Diego, University of California, San Francisco, University of Southern California, Virginia Commonwealth University, Emory University, Children's Hospital Medical Center, Cincinnati
Liver Diseases
06/25
06/25
Brigham, Dania
PROBE, NCT00061828: A Prospective Database of Infants With Cholestasis

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia, Neonatal Cholestasis
05/29
05/29
BASIC, NCT00345553: Biliary Atresia Study in Infants and Children

Recruiting
N/A
1265
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia
05/29
05/29
LOGIC, NCT00571272: Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis

Suspended
N/A
1675
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Liver Diseases, Alagille Syndrome, Alpha 1-Antitrypsin Deficiency
05/29
05/29
MITOHEP, NCT01148550: Longitudinal Study of Mitochondrial Hepatopathies

Suspended
N/A
67
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Michigan
Acute Liver Failure, Mitochondrial Diseases, End Stage Liver Disease, Respiratory Chain Deficiencies, Mitochondrial, Disorder of Fatty Acid Oxidation
05/29
05/29
NCT04181138: Primary Sclerosing Cholangitis in Children

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Primary Sclerosing Cholangitis, Liver Diseases, Cholangitis, Sclerosing
05/29
05/29
Cavallo, Laurel
PROBE, NCT00061828: A Prospective Database of Infants With Cholestasis

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia, Neonatal Cholestasis
05/29
05/29
BASIC, NCT00345553: Biliary Atresia Study in Infants and Children

Recruiting
N/A
1265
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia
05/29
05/29
LOGIC, NCT00571272: Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis

Suspended
N/A
1675
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Liver Diseases, Alagille Syndrome, Alpha 1-Antitrypsin Deficiency
05/29
05/29
NCT05272319: Genetic Collection Protocol

Recruiting
N/A
2230
Canada, US
Arbor Research Collaborative for Health
Liver Diseases
05/29
05/29
Cavallo, Laurell
MITOHEP, NCT01148550: Longitudinal Study of Mitochondrial Hepatopathies

Suspended
N/A
67
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Michigan
Acute Liver Failure, Mitochondrial Diseases, End Stage Liver Disease, Respiratory Chain Deficiencies, Mitochondrial, Disorder of Fatty Acid Oxidation
05/29
05/29
Shaw, Alison
NCT04181138: Primary Sclerosing Cholangitis in Children

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Primary Sclerosing Cholangitis, Liver Diseases, Cholangitis, Sclerosing
05/29
05/29
NCT03325855: Fecal Microbiota Transplant National Registry

Recruiting
N/A
4000
Canada, US
None - Observational, Observational
American Gastroenterological Association, OpenBiome, University of California, San Diego, Commure, University of Pennsylvania, University of Minnesota, Loyola University Chicago
Fecal Microbiota Transplantation, Clostridium Difficile Infection, Gut Microbiome
08/27
08/27
Tessier, Mary Elizabeth
NCT04181138: Primary Sclerosing Cholangitis in Children

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Primary Sclerosing Cholangitis, Liver Diseases, Cholangitis, Sclerosing
05/29
05/29
Olvera, Diego
NCT04454463: Nonalcoholic Fatty Liver Disease (NAFLD) Database 3

Active, not recruiting
N/A
1640
US
Johns Hopkins Bloomberg School of Public Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Baylor College of Medicine, Case Western Reserve University, Duke University, Ann & Robert H Lurie Children's Hospital of Chicago, Indiana University, Liver Institute Northwest, Seattle Children's Hospital, St. Louis University, University of California, San Diego, University of California, San Francisco, University of Southern California, Virginia Commonwealth University, Emory University, Children's Hospital Medical Center, Cincinnati
Liver Diseases
06/25
06/25
Harris, Katelynn
PROBE, NCT00061828: A Prospective Database of Infants With Cholestasis

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia, Neonatal Cholestasis
05/29
05/29
BASIC, NCT00345553: Biliary Atresia Study in Infants and Children

Recruiting
N/A
1265
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biliary Atresia
05/29
05/29
LOGIC, NCT00571272: Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis

Suspended
N/A
1675
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Liver Diseases, Alagille Syndrome, Alpha 1-Antitrypsin Deficiency
05/29
05/29
MITOHEP, NCT01148550: Longitudinal Study of Mitochondrial Hepatopathies

Suspended
N/A
67
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Michigan
Acute Liver Failure, Mitochondrial Diseases, End Stage Liver Disease, Respiratory Chain Deficiencies, Mitochondrial, Disorder of Fatty Acid Oxidation
05/29
05/29
NCT04181138: Primary Sclerosing Cholangitis in Children

Recruiting
N/A
1000
Canada, US
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Primary Sclerosing Cholangitis, Liver Diseases, Cholangitis, Sclerosing
05/29
05/29
NCT05272319: Genetic Collection Protocol

Recruiting
N/A
2230
Canada, US
Arbor Research Collaborative for Health
Liver Diseases
05/29
05/29
Fay, Alexander
NCT06199531: Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency

Recruiting
1/2
12
US
GS-100, Recombinant, single-stranded adeno-associated virus serotype 9 (AAV9) vector that encodes a full-length version of human NGLY1
Grace Science, LLC
NGLY1 Deficiency
01/28
01/28
CANaspire, NCT04998396: A Study of AAV9 Gene Therapy in Participants With Canavan Disease ( Clinical Trial)

Recruiting
1/2
26
US
AAV9 BBP-812
Aspa Therapeutics
Canavan Disease
10/26
10/30
CANinform, NCT04126005: Natural History Study of Patients With Canavan Disease ( Study)

Recruiting
N/A
70
Europe, US
Aspa Therapeutics
Canavan Disease
12/25
04/26
NCT03047369: The Myelin Disorders Biorepository Project

Recruiting
N/A
12000
US
Children's Hospital of Philadelphia, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS), National Center for Advancing Translational Sciences (NCATS), Biogen, Eli Lilly and Company, Myrtelle Inc., Orchard Therapeutics Ltd., Passage Bio, Inc., Synaptix Biotherapeutics Ltd., Takeda, Boehringer Ingelheim, Ionis Pharmaceuticals, Inc., Sanofi Winthrop Industrie, Sana Biotechnology, Yaya Foundation for 4H Leukodystrophy, University of Pennsylvania, United MSD Foundation, Foundation to Fight H-ABC, Calliope Joy Foundation, Don't Forget Me Foundation
Leukodystrophy, White Matter Disease, Leukoencephalopathies, 4H Syndrome, Adrenoleukodystrophy, AMN, ALD, ALD Gene Mutation, ALD (Adrenoleukodystrophy), X-linked Adrenoleukodystrophy, X-ALD, Adrenomyeloneuropathy, Aicardi Goutieres Syndrome, AGS, Alexander Disease, Alexanders Leukodystrophy, AxD, ADLD, Canavan Disease, CTX, Cerebrotendinous Xanthomatoses, Krabbe Disease, GALC Deficiency, Globoid Leukodystrophy, TUBB4A-Related Leukodystrophy, H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum, HBSL, HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity, LBSL, Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder), Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation, ALSP, CSF1R Gene Mutation, HCC - Hypomyelination and Congenital Cataract, MLC1, Megalencephalic Leukoencephalopathy With Subcortical Cysts, MLD, Metachromatic Leukodystrophy, PMD, Pelizaeus-Merzbacher Disease, PLP1 Null Syndrome, PLP1 Gene Duplication | Blood or Tissue | Mutations, Pelizaeus Merzbacher Like Disease, Peroxisomal Biogenesis Disorder, Zellweger Syndrome, Refsum Disease, Salla Disease, Sialic Storage Disease, Sjögren, Sjogren-Larsson Syndrome, Van Der Knapp Disease, Vanishing White Matter Disease, Charcot-Marie-Tooth, CMT, Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency, Allan-Herndon-Dudley Syndrome, Cadasil, Cockayne Syndrome, Multiple Sulfatase Deficiency, Gangliosidoses, GM2 Gangliosidosis, BPAN, Labrune Syndrome, LCC, Mucopolysaccharidoses, TBCK-Related Intellectual Disability Syndrome
12/30
12/30

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