| Lee, Kyung Hee |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
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| Enrolling by invitation | 2/3 | 308 | RoW | mFOLFIRINOX, mFOLFOX 6 | Chungnam National University Hospital, Boryung Pharmaceutical Co., Ltd | Colon Cancer Stage III | 03/25 | 03/28 | | |
SOLAR, NCT05673772: Preoperative Sequential Short-course Radiation Therapy and FOLFOX for Locally Advanced Rectal Cancer |
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| Recruiting | 2 | 364 | RoW | short-course radiotherapy, mFOLFOX6, Chemoradiotherapy, TME surgery | Kyungpook National University Hospital, National Cancer Center, Korea | Rectal Cancer | 12/24 | 12/29 | | |
NCT03763604: Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer |
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| Approved for marketing | N/A | | Europe, Canada, RoW | Abemaciclib, LY2835219 | Eli Lilly and Company | Metastatic Breast Cancer | | | | |
| Ho, Gwo Fuang |
AUROR, NCT03989089: Study of Pembrolizumab in Metastatic HER2-negative Breast Cancer Patients With APOBEC3B Mutation |
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| Active, not recruiting | 2 | 44 | RoW | Pembrolizumab, Keytruda | University of Malaya, Merck Sharp & Dohme LLC, National University Hospital, Singapore, Cancer Research Malaysia | HER2-Negative Breast Cancer | 12/25 | 12/26 | | |
NCT05288127: Efficacy of Talazoparib in Asian Metastatic Breast Cancer Patients With a Homologous Recombinant Deficiency (HRD) Signature |
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| Recruiting | 2 | 55 | RoW | Talazoparib | University of Malaya, Cancer Research Malaysia, Pfizer, Pantai Hospital Kuala Lumpur, Hospital Sultan Ismail | HRD 100 Gene Expression High, Triple Negative Breast Cancer | 06/24 | 11/25 | | |
| Recruiting | 2 | 30 | Europe, Canada, RoW | Eribulin Mesylate, Halaven, Pembrolizumab, Keytruda | Australia New Zealand Gynaecological Oncology Group, Eisai Inc., Merck Sharp & Dohme LLC | Ovarian Carcinosarcoma, Uterine Carcinosarcoma | 03/25 | 12/26 | | |
NCT03763604: Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer |
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| Approved for marketing | N/A | | Europe, Canada, RoW | Abemaciclib, LY2835219 | Eli Lilly and Company | Metastatic Breast Cancer | | | | |
| Souza, Pedro Augusto M |
| Terminated | 2 | 19 | Europe, US, RoW | Daxdilimab, Placebo (Normal Saline) | Amgen, Horizon Therapeutics Ireland DAC | Lupus Nephritis | 01/24 | 01/24 | | |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
| Zhang, Hongwei |
NCT05745259: Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ） |
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| Recruiting | 3 | 1630 | RoW | Alteplase, rt-PA, Tenecteplase, TNK-tPA | Beijing Tiantan Hospital, Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd, The Place Pharmaceutical(Jiangsu) Co., Ltd | Acute Ischemic Stroke | 11/23 | 03/24 | | |
NCT06074809: RCT on the Treatment of Menopausal Syndrome With Chinese Medicine |
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| Not yet recruiting | 2 | 78 | RoW | Modified Guizhi Fuling granules, Chinese medicine, Placebo | Chinese University of Hong Kong | Menopause | 10/25 | 01/26 | | |
NCT06095258: A Practical RCT of TCM in the Treatment of LCOVID and Analysis of Syndrome Types and Medication Characteristics. |
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| Not yet recruiting | 2 | 162 | NA | Traditional Chinese medicine treatment, CM group, Western medicine treatment, WM group | Chinese University of Hong Kong | Long COVID | 11/25 | 02/26 | | |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
NCT05717712: Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma |
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| Recruiting | 1 | 18 | RoW | Ad-TD-nsIL12 | Capital Medical University | Oncolytic Virus, Diffuse Intrinsic Pontine Glioma, Adverse Drug Event | 01/25 | 01/28 | | |
NCT05717699: Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma |
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| Recruiting | 1 | 18 | RoW | Ad-TD-nsIL12 | Capital Medical University | Oncolytic Virus, Diffuse Intrinsic Pontine Glioma, Adverse Drug Event | 01/25 | 01/28 | | |
NCT05860790: Prospective Validation of Clinical Prediction Model for Venous Thromboembolism Following Neurosurgery |
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| Recruiting | N/A | 1000 | RoW | Clinical Prediction Model for Venous Thromboembolism Following Neurosurgery | Capital Medical University | Venous Thromboembolism, Neurosurgery, Risk Assessment | 06/23 | 07/23 | | |
NCT06166082: Stanford Neuromodulation Therapy (SNT) for the Treatment-Resistant Depression |
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| Recruiting | N/A | 130 | RoW | Active iTBS-DLPFC, Sham iTBS-DLPFC | Changping Laboratory, Xianyue Hospital, Xiamen, Hebei Mental Health Center, Baoding, HuiLongGuan Hospital, Beijing, Wuhan Mental Health Center, Wuhan, Zhumadian Second People's Hospital, Zhumadian | Treatment Resistant Depression | 07/24 | 10/24 | | |
NCT04289701: Hypertension Registry of "Hypertension Prevention and Control Initiative in China" |
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| Recruiting | N/A | 200000 | RoW | Health Services for Systematic Hypertension Management | Chinese Academy of Medical Sciences, Fuwai Hospital | Hypertension | 12/22 | 12/24 | | |
| Kamarulzaman, Adeeba |
| Completed | N/A | 1702 | RoW | Methadone, Isoniazid, Rifapentine | Yale University, University of Malaya, National Institute on Drug Abuse (NIDA) | Opioid Dependence, Addiction, HIV/AIDS, Tuberculosis, Hepatitis | 04/24 | 04/24 | | |
| Wang, Chew Yin |
NCT03310125 / 2017-003836-35: Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF) |
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| Completed | 3 | 3209 | Europe, Canada, US, RoW | Colchicine, Placebo | Population Health Research Institute, Hamilton Health Sciences Corporation | Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery | 07/23 | 07/23 | | |
| Recruiting | N/A | 1100 | Europe, Canada, US, RoW | Accelerated medical clearance and surgery | Population Health Research Institute, Canadian Institutes of Health Research (CIHR), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Hip Fractures, Myocardial Injury | 02/27 | 05/27 | | |
NCT05509335: Ultrasound Assessment On Effectiveness of Cricoid Pressure In Paediatric Population |
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| Recruiting | N/A | 90 | RoW | | University of Malaya | Aspiration of Food, Pediatric ALL | 12/23 | 12/23 | | |
| Chaw, Sook Hui |
HOTON, NCT04654429: Does Higher OT Temperature and IV Ondansetron Reduce Incidence of PSS in Parturients? |
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| Recruiting | 4 | 628 | RoW | IV Ondansetron 4mg, Pharmacological intervention, Higher OT temperature range, Non-pharmacological intervention, Placebo, Control, Lower OT temperature Range | Dr Lim Siu Min | Temperature Change, Body, Chills, Tremor, Nausea, Postoperative, Vomiting, Postoperative, Postoperative Shivering | 12/22 | 12/22 | | |
| Lee, Jong-Young |
BETTER, NCT05761444: Effectiveness and Safety Study of Early add-on of Ezetimibe With Atorvastatin in Very High-risk Patients |
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| Completed | 4 | 137 | RoW | Atozet 10/40 mg or 10/80 mg, Lipitor 40 mg or 80 mg | Organon and Co, Iqvia Pty Ltd | Atherosclerotic Cardiovascular Disease | 09/24 | 10/24 | | |
ASSURE-DES, NCT02797548: Perioperative Antiplatelet Therapy in Patients With Drug-eluting Stent Undergoing Noncardiac Surgery |
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| Completed | 4 | 1010 | RoW | Aspirin only, No antiplatelet therapy | Jung-min Ahn, CardioVascular Research Foundation, Korea | Antiplatelet Drugs | 05/24 | 05/24 | | |
PROTECT-HBR, NCT04416581: Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic Therapy |
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| Recruiting | 4 | 3100 | RoW | PPI, P-CAB 50 | Duk-Woo Park, MD | Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndrome, Myocardial Infarction | 09/26 | 12/27 | | |
IVUS-CAMS, NCT02845505: Intravascular Ultrasound Prediction of Myocardial Size and Coronary Computed Tomography-Derived Ischemic Burden for Coronary Lesion |
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| Active, not recruiting | N/A | 500 | RoW | Intravascular Ultrasound, coronary computed tomography angiography | Asan Medical Center, Boston Scientific Corporation | Coronary Artery Disease | 04/22 | 06/24 | | |
DCB-SFA, NCT02648334: Randomized Comparison of DCB for the Treatment of Superficial Femoral and Popliteal Peripheral Artery Disease |
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| Completed | N/A | 443 | RoW | IN.PACT drug coated balloon, Lutonix drug coated balloon | Seung-Whan Lee, M.D., Ph.D. | Angioplasty, Balloon, Catheterization, Peripheral, Popliteal Artery, Femoral Artery | 01/23 | 08/24 | | |
| Recruiting | N/A | 4500 | RoW | Onyx Drug Eluting Stent group | Seung-Jung Park, CardioVascular Research Foundation, Korea, Medtronic Korea Co., Ltd. | Coronary Artery Disease, Arterial Occlusive Diseases, Cardiovascular Diseases, Percutaneous Transluminal Angioplasty | 12/25 | 12/29 | | |
NCT05807841: Clinical Impact of Intravascular Ultrasound-Based Artificial Intelligence Technologies (INNOVATE-PCI) |
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| Recruiting | N/A | 3000 | RoW | percutaneous coronary intervention | Asan Medical Center, Boston Scientific Corporation | Coronary Artery Disease | 06/28 | 06/29 | | |
REVERSE, NCT05846893: Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Disease |
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| Recruiting | N/A | 1436 | RoW | SeQuent® Please NEO drug-coated balloon catheter, Current-generation drug-eluting stent | B. Braun Medical Industries Sdn. Bhd., B. Braun Melsungen AG, Ulsan University Hospital, European Cardiovascular Research Center, Seoul National University Hospital, Universität des Saarlandes | Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Coronary Stenosis, De Novo Stenosis | 10/26 | 09/28 | | |
ASSIST, NCT05529459: Anatomic Versus Physiologic Guidance for Complete Revascularization With DES Eluting in Patients With CAD |
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| Recruiting | N/A | 2400 | RoW | Percutaneous Coronary Intervention | Seung-Whan Lee, M.D., Ph.D., Biotronik Korea Co., Ltd | Coronary Disease | 12/26 | 07/30 | | |
| Recruiting | N/A | 1350 | RoW | Percutaneous coronary intervention | Samsung Medical Center, Seoul St. Mary's Hospital, Seoul National University Bundang Hospital, Korea University Ansan Hospital, Chonnam National University Hospital, Chung-Ang University Gwangmyeong Hospital, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gyeongsang National University Hospital, Uijeongbu St. Mary Hospital, Keimyung University Dongsan Medical Center, Inha University Hospital, Chungbuk National University, Wonju Severance Christian Hospital, SMG-SNU Boramae Medical Center, Kangbuk Samsung Hospital, Sungkyunkwan University, Ewha Womans University, Korea University Guro Hospital | Coronary Artery Disease | 07/27 | 12/28 | | |
STRIKE-CTO, NCT03667196: Evaluation of Effectiveness and Safety of Antegrade and Retrograde Approach of Percutaneous Coronary Intervention for Chronic Total Occlusions |
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| Recruiting | N/A | 4000 | RoW | antegrade and retrograde approach | Seung-Whan Lee, M.D., Ph.D., Abbott Medical Devices, Biotronik SE & Co. KG, Medtronic, Dio Medical | Chronic Total Occlusion of Coronary Artery | 12/27 | 12/27 | | |
| Riella, Miguel Carlos |
| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
| Recruiting | 3 | 2750 | Europe, Canada, RoW | Spironolactone 25Mg Tablet, Placebo Oral Tablet | Population Health Research Institute, Canadian Institutes of Health Research (CIHR) | Endstage Renal Disease | 07/25 | 04/26 | | |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
| Deboni, Luciane Mônica |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
| Noronha, Irene de Lourdes |
| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
| Terminated | 2 | 19 | Europe, US, RoW | Daxdilimab, Placebo (Normal Saline) | Amgen, Horizon Therapeutics Ireland DAC | Lupus Nephritis | 01/24 | 01/24 | | |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
| Keiserman, Mauro |
BEconneCTD-ILD, NCT06572384: A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease |
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| Recruiting | 3 | 440 | Europe, Japan, US, RoW | Belimumab, BENLYSTA, GSK1550188, Placebo | GlaxoSmithKline | Lung Diseases, Interstitial | 10/28 | 12/28 | | |
NCT06716606: A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease |
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| Recruiting | 3 | 225 | RoW | Belimumab | GlaxoSmithKline, ICON plc | Bronchial Diseases | 07/28 | 01/30 | | |
TOPAZ-1, NCT04895241 / 2020-005775-12: A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus |
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| Recruiting | 3 | 540 | Europe, US, RoW | Litifilimab, BIIB059, Placebo | Biogen | Lupus Erythematosus, Systemic | 09/26 | 03/27 | | |
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| Recruiting | 2/3 | 474 | Europe, Canada, Japan, US, RoW | Litifilimab, BIIB059, Placebo | Biogen, Biogen Idec Research Limited | Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus | 10/26 | 12/27 | | |
BLISSc-ILD, NCT05878717: A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease |
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| Recruiting | 2/3 | 300 | Europe, Japan, US, RoW | Belimumab, BENLYSTA™, GSK1550188, LymphoStat-B™, BENLYSTATM, GSK1550188, LymphoStat-B™, Placebo | GlaxoSmithKline | Systemic Sclerosis Associated Interstitial Lung Disease, Scleroderma, Systemic | 07/27 | 07/27 | | |
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| Terminated | 2 | 19 | Europe, US, RoW | Daxdilimab, Placebo (Normal Saline) | Amgen, Horizon Therapeutics Ireland DAC | Lupus Nephritis | 01/24 | 01/24 | | |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
| Said, Mas Ayu |
NCT04953650: Intermittent Fasting Towards Elevated Blood Pressure |
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| Completed | N/A | 140 | RoW | Intermittent fasting, No intervention | University of Malaya, University of Muhammadiyah Aceh | Intermittent Fasting, Elevated Blood Pressure | 03/22 | 03/22 | | |
| Ye, Zhiming |
NCT04381143: ASPIrin in Reducing Events in Dialysis ( ASPIRED ) |
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| Recruiting | 4 | 9000 | RoW | Aspirin 100 mg Oral Tablet, Matching Placebo | Guangdong Provincial People's Hospital, The George Institute | CKD (Chronic Kidney Disease) Stage 5D | 09/26 | 12/26 | | |
NCT06470191: A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy. |
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| Recruiting | 2/3 | 216 | RoW | B007, Cyclosporin Capsules | Shanghai Jiaolian Drug Research and Development Co., Ltd, Shanghai Pharmaceuticals Holding Co., Ltd | Primary Membranous Nephropathy | 12/26 | 12/26 | | |
NCT05810948: A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients with Lupus Nephritis (ZL-1103-013) |
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| Active, not recruiting | 2 | 73 | RoW | efgartigimod IV, Placebo | argenx, Zai Lab (Shanghai) Co., Ltd. | Lupus Nephritis | 07/25 | 09/25 | | |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
NCT06774664: A Clinical Study of SCTC21C in Participants With Plasma Cell-driven Autoimmune Diseases |
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| Not yet recruiting | 1/2 | 99 | RoW | SCTC21C | Sinocelltech Ltd. | IgA Nephropathy | 09/27 | 03/29 | | |
DKTAVG, NCT06503692: Scoring Balloon and High Pressure Balloon in the Treatment of Arteriovenous Graft Stenosis |
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| Recruiting | N/A | 140 | RoW | DKutting PTA Scoring Balloon Dilatation Catheter, Scoring Balloon, Peripheral Balloon Catheter | DK Medical Technology (Suzhou) Co., Ltd. | Arteriovenous Graft Stenosis | 12/26 | 12/26 | | |
NCT05190848: Correlation of Microbiome and Metabonomics With IgA Nephropathy |
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| Recruiting | N/A | 600 | RoW | | Guangdong Provincial People's Hospital | IgA Nephropathy | 12/24 | 12/24 | | |
NCT05188885: A Real World, Multi-centric, Observational Registry Study of Chronic Kidney Diseases |
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| Recruiting | N/A | 90000 | RoW | | Guangdong Provincial People's Hospital | Chronic Kidney Disease | 12/26 | 12/28 | | |
| Araújo, Maria das Graças |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
| Kaplan, Muhammet Ali |
| Active, not recruiting | 3 | 368 | Europe, US, RoW | Abemaciclib, Fulvestrant, Placebo | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasm, Neoplasm Metastasis | 02/24 | 02/26 | | |
EMBER-3, NCT04975308 / 2021-000079-35: A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer |
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| Active, not recruiting | 3 | 866 | Europe, Japan, US, RoW | Imlunestrant, LY3484356, Exemestane, Fulvestrant, Abemaciclib, LY2835219 | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasms, Neoplasm Metastasis | 06/24 | 08/27 | | |
| Recruiting | 3 | 918 | Europe, Canada, Japan, RoW | Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil | Jazz Pharmaceuticals, BeiGene, Ltd. | Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma | 05/25 | 05/26 | | |
CYCLONE 3, NCT05288166: A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) |
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| Active, not recruiting | 3 | 900 | Europe, Canada, Japan, US, RoW | Abemaciclib, LY2835219, Abiraterone, Prednisone or Prednisolone, Placebo for Abemaciclib | Eli Lilly and Company | Prostatic Neoplasms, Neoplasm Metastasis, Urogenital Neoplasms, Physiological Effects of Drugs, Antineoplastic Agents, Antineoplastic Agents, Hormonal, Androgens, Hormones, Hormones, Hormone Substitutes, and Hormone Antagonists, Abiraterone Acetate, Steroid Synthesis Inhibitors, Cytochrome P-450, Enzyme Inhibitors, Prednisone, Prednisolone, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6 | 02/24 | 10/27 | | |
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer |
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| Recruiting | 3 | 1016 | Europe, Canada, Japan, US, RoW | LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed | Eli Lilly and Company, Loxo Oncology, Inc. | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 10/26 | 10/29 | | |
| Recruiting | 3 | 170 | Europe, Canada, Japan, US, RoW | Selpercatinib, LY3527723, LOXO-292, Placebo | Loxo Oncology, Inc., Eli Lilly and Company | Carcinoma, Non-Small-Cell Lung | 05/27 | 08/32 | | |
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
| Roslani, April C |
NCT05039411: Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas Patients With Crohn's Disease |
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| Recruiting | 1 | 5 | RoW | PF2020-CELL (UC-MSCs) - Allogeneic Human Umbilical Cord Mesenchymal Stem Cells | CryoCord Sdn Bhd, University of Malaya | Perianal Fistula Due to Crohn's Disease, Fistula in Ano | 12/24 | 01/25 | | |
LASERLIFT, NCT06212739: Post-op Pain After Fistula Laser Closure or Ligation of the Intersphincteric Tract for Anal Fistula |
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| Completed | N/A | 56 | RoW | Laser, FiLAC, LIFT, Ligation of the Intersphincteric Fistula Tract | University of Malaya | Fistula in Ano | 12/20 | 08/21 | | |
NCT06684067: Effect of Patient Navigation on Colonoscopy Completion Screening Rate for Colorectal Cancer. |
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| Completed | N/A | 52 | RoW | Patient navigation | University of Malaya, Ministry of Health, Malaysia | Colorectal Cancer Screening, Patient Navigation | 02/22 | 03/22 | | |
| Vethakkan, Shireene R |
| Recruiting | N/A | 400 | RoW | Blood sampling | University of Malaya | Metabolic Syndrome X | 12/18 | 12/24 | | |
| HASAN, MOHD SHAHNAZ |
| Completed | 4 | 115 | RoW | Lignocaine, Group A, Normal saline, Group B | University of Malaya | Adolescent Idiopathic Scoliosis, Analgesia | 03/22 | 09/22 | | |
PONV, NCT05956899: Palonosetron vs Ondansetron In Prophylaxis Among Idiopathic Scoliosis Patients |
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| Completed | 4 | 92 | RoW | Palonosetron, Ondansetron | University of Malaya | Idiopathic Scoliosis, Postoperative Nausea and Vomiting | 03/24 | 05/24 | | |
PONV, NCT06540885: A Comparison Between Palonosetron Versus Granisetron as Prophylaxis in Scoliotic Patients Undergoing Spine Surgery |
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| Not yet recruiting | 4 | 74 | RoW | Palonosetron (Group P), antiemetic, Granisetron (Group G) | University of Malaya | Postoperative Nausea and Vomiting, Scoliosis | 07/26 | 09/26 | | |
NCT03319329: Metabolic Determinants Of Resting Energy Expenditure Among Mechanically Ventilated Critically Ill Patients |
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| Recruiting | N/A | 314 | RoW | Indirect Calorimetry | University of Malaya | Critical Illness | 12/20 | 12/22 | | |
NCT04533100: The Association of Protein-Energy Adequacy With Mortality in Critically Ill Patients With Acute Kidney Injury. |
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| Recruiting | N/A | 185 | RoW | | University of Malaya | Critical Illness, Acute Kidney Injury | 07/21 | 08/21 | | |
NCT05226858: Transesophageal Echocardiography To Diagnose Blunt Traumatic Aortic Injury Traumatic Aortic Injury |
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| Recruiting | N/A | 56 | RoW | Transesophageal echocardiography (TEE) | Hospital Raja Permaisuri Bainun, Hospital Sultanah Bahiyah, Kuala Lumpur General Hospital, Hospital Melaka, Hospital Queen Elizabeth, Malaysia, University of Malaya | Trauma Chest | 12/23 | 12/23 | | |
| Chan, Lee Lee |
| Recruiting | 2 | 500 | RoW | Prednisolone, Dexamethasone, Vincristine, Methotrexate, L-Asparaginase, Pegylated asparaginase, Erwinase, Dasatinib, Imatinib, Cyclophosphamide, Cytarabine, Mercaptopurine, Thioguanine, Rituximab, Doxorubicin, Fludarabine | National University Hospital, Singapore | B Lymphoblastic Leukemia | 03/30 | 03/30 | | |
NCT03286634: ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016 |
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| Recruiting | 2 | 60 | Japan, RoW | Daunorubicin, DNR, Prednisolone, Pred, Vincristine, VCR, Epirubicin, EPI, E-coli L-asparaginase, E-coli L-Asp, 6-Mercaptopurine, 6-MP, Methotrexate, MTX, Hydrocortisone, Cytarabine, Ara-C, Cyclophosphamide, Cy | National Hospital Organization Nagoya Medical Center | Down Syndrome, Acute Lymphoblastic Leukemia, Childhood Cancer | 03/28 | 03/33 | | |
| Nathan, Anna |
NCT04765033: Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD. |
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| Completed | 4 | 46 | RoW | Nebulized 5% Hypertonic saline, Placebo | University of Malaya | Bronchiectasis | 08/23 | 08/23 | | |
MSIP PCV, NCT04923035: Paediatric Pneumococcal Pneumonia in Malaysia Prior to and During Pneumococcal Conjugate Vaccine (PCV) Implementation |
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| Active, not recruiting | N/A | 1010 | RoW | | International Medical University, University of Malaya, Universiti Sains Malaysia, International Islamic University Malaysia, University of Southampton, Merck Sharp & Dohme LLC | Pneumonia, Pneumococcal, Pneumonia Childhood | 08/23 | 12/24 | | |
| Ikeyama, Takanari |
| Recruiting | 3 | 500 | Canada, Japan, US, RoW | Hydrocortisone, sodium succinate, SOLU-CORTEF- hydrocortisone sodium succinate injection, Normal saline | Jerry Zimmerman, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Canadian Institutes of Health Research (CIHR), Canadian Critical Care Trials Group, Children's Hospital of Eastern Ontario | Septic Shock | 09/26 | 12/26 | | |
| Recruiting | N/A | 150000 | Europe, Canada, Japan, US, RoW | | Children's Hospital of Philadelphia, Agency for Healthcare Research and Quality (AHRQ) | Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication | 01/30 | 01/30 | | |
| Tsan, Samuel E H |
NCT06127628: Effectiveness of Ultrasound-guided Scalp Block for Supratentorial Craniotomy |
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| Recruiting | N/A | 60 | RoW | Ultrasound-guided scalp block with ropivacaine 0.375% | University Malaysia Sarawak | Pain, Postoperative, Anesthesia | 03/25 | 10/25 | | |
| Pang |
WU-KONG1, NCT03974022: Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer with EGFR or HER2 Mutation |
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| Active, not recruiting | 1/2 | 315 | Europe, Canada, Japan, US, RoW | Sunvozertinib, DZD9008 | Dizal Pharmaceuticals | Non-Small Cell Lung Cancer | 07/24 | 07/25 | | |
| Wall, Lucy |
| Recruiting | 3 | 918 | Europe, Canada, Japan, RoW | Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil | Jazz Pharmaceuticals, BeiGene, Ltd. | Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma | 05/25 | 05/26 | | |
| Wan, Azman Wan Ahmad |
NCT03616132: A First-in-Man Study to Evaluate the Feasibility and Safety of Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System |
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| Recruiting | N/A | 15 | RoW | Device: Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System | Lifetech Scientific (Shenzhen) Co., Ltd. | Single Coronary Vessel Disease | 03/19 | 03/23 | | |
| Mohamed, Raja Jasmine Raja |
NCT06131905: Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in Colonoscopy |
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| Not yet recruiting | 2/3 | 60 | NA | Magnesium Sulfate, Propofol | Assiut University | Magnesium, Intraoperative Analgesia | 01/25 | 12/25 | | |
| Ulanska, Malgorzata |
| Active, not recruiting | 3 | 368 | Europe, US, RoW | Abemaciclib, Fulvestrant, Placebo | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasm, Neoplasm Metastasis | 02/24 | 02/26 | | |
| Recruiting | 3 | 918 | Europe, Canada, Japan, RoW | Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil | Jazz Pharmaceuticals, BeiGene, Ltd. | Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma | 05/25 | 05/26 | | |
GALAXIES Lung-301, NCT06472076: A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC) |
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| Recruiting | 3 | 1000 | Europe, Canada, Japan, RoW | Dostarlimab, Belrestotug, Pembrolizumab, Placebo | GlaxoSmithKline, iTeos Therapeutics | Lung Cancer, Non-Small Cell | 09/28 | 09/29 | | |
| Active, not recruiting | 2 | 182 | Europe, RoW | 6-Thio-2'-Deoxyguanosine, 6-thio-dG, THIO, Cemiplimab, LIBTAYO® | Maia Biotechnology, MAIA Biotechnology, Inc. | Carcinoma, Non-Small-Cell Lung | 08/25 | 10/26 | | |
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| Active, not recruiting | 1/2 | 49 | Europe, Japan, US, RoW | TAK-981, Pembrolizumab | Takeda, Takeda Development Center Americas, Inc. | Advanced or Metastatic Solid Tumors | 11/25 | 11/25 | | |
| Hilmi, Ida Normiha |
| Recruiting | 3 | 1063 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis | 07/26 | 12/27 | | |
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| Lee, Choon Kin |
| Recruiting | 3 | 1063 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis | 07/26 | 12/27 | | |
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| Ng, Wei Shan |
NCT05099900: Exploration of Women's Experiences and Technology Usage Before, During, and After Pregnancy in Singapore |
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| Recruiting | N/A | 60 | RoW | | National University, Singapore | Pregnancy Related | 05/22 | 11/22 | | |
| Completed | N/A | 37 | RoW | Dengue self-monitoring system, DeSMoS | University of Malaya, Ministry of Health, Malaysia | Dengue | 06/23 | 06/23 | | |
| Shariffuddin, Ina Ismiarti binti |
NCT04642521: Association Between Anaemia and Handgrip Strength in Female Planned for Major Surgery and the Effect of Intravenous Iron on Handgrip Strength |
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| Not yet recruiting | N/A | 65 | RoW | Jamar hydraulic hand dynamometer, Handgrip strength | University of Malaya, Ministry of Health, Malaysia | Anemia, Iron-deficiency, Patient Blood Management, Iron Deficiency Anemia | 03/21 | 04/21 | | |
NCT05112393: Development and Validation of Creatinine-Based Estimates of the Glomerular Filtration Rate Equation |
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| Not yet recruiting | N/A | 200 | RoW | Development of new estimating Glomerular Filtration Rate (eGFR) equation, Validation of new estimating Glomerular Filtration Rate (eGFR) equation | University of Malaya | Renal Function Disorder | 08/22 | 12/22 | | |
| Toh, Yok Yong |
AUROR, NCT03989089: Study of Pembrolizumab in Metastatic HER2-negative Breast Cancer Patients With APOBEC3B Mutation |
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| Active, not recruiting | 2 | 44 | RoW | Pembrolizumab, Keytruda | University of Malaya, Merck Sharp & Dohme LLC, National University Hospital, Singapore, Cancer Research Malaysia | HER2-Negative Breast Cancer | 12/25 | 12/26 | | |
| Gan, Chin Seng |
| Recruiting | 3 | 500 | Canada, Japan, US, RoW | Hydrocortisone, sodium succinate, SOLU-CORTEF- hydrocortisone sodium succinate injection, Normal saline | Jerry Zimmerman, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Canadian Institutes of Health Research (CIHR), Canadian Critical Care Trials Group, Children's Hospital of Eastern Ontario | Septic Shock | 09/26 | 12/26 | | |
