University of Miami Bascom Palmer Eye Institute
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 4 Trials 
26 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Lee, Wendy W
NCT04831047: The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye Appearance

Completed
4
114
US
Oxymetazoline hydrochloride 0.1% ophthalmic solution, Upneeq, Placebo, Balanced saline solution
University of Miami
Ptosis, Eyelid, Conjunctiva Inflamed, Eye Manifestations
04/22
04/22
NCT06080438: Effect of Topical Botulinum Toxin Eyedrop on Palpebral Fissure

Terminated
4
2
US
Botulinum toxin, BOTOX
University of Miami
Tears; Excess, Eyelid Spasm
07/24
07/24
NCT05672407: The Role of Local Tranexamic Acid on Periorbital Oculoplastic Surgery

Withdrawn
4
150
NA
Tranexamic acid, Placebo, Balanced Saline Solution
University of Miami
Eyelid Diseases, Periorbital Disorder, Hemorrhage, Surgical Blood Loss
06/26
06/26
THRIVE, NCT05176639 / 2021-006794-37: A Safety, Tolerability and Efficacy Study of Veligrotug (VRDN 001) in Healthy Volunteers and Participants with Thyroid Eye Disease (TED) ( )

Active, not recruiting
3
154
Europe, Canada, US, RoW
Veligrotug (VRDN-001) Phase 1/2 MAD (HV and TED), VRDN-001 Phase 3 Cohort (THRIVE), VRDN-001 Placebo
Viridian Therapeutics, Inc., Viridian Therapeutics, Inc.
Thyroid Eye Disease
07/24
03/25
NCT05007288: Restorative Eye Treatment and INhance in Upper Eyelid Blepharoplasty Surgery

Completed
N/A
13
US
Restorative Eye Treatment (RET) cream, INhance with Trihex Technology
University of Miami
Eyelid Dermatochalasis, Dermatochalasis
04/22
07/22
Wester, Sara
NCT05890027: Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation

Recruiting
4
30
US
Phenylephrine Ophthalmic, Eyelid Tape
University of Miami
Ptosis, Eyelid
03/25
03/25
NCT05002998: TEPEZZA® (Teprotumumab-trbw) Post-Marketing Requirement Study

Active, not recruiting
4
313
Europe, US
Teprotumumab, TEPEZZA, Placebo, Saline Solution
Amgen
Thyroid Eye Disease
04/26
04/26
Lam, Byron
IIH EVOLVE, NCT05347147 / 2021-006664-24: A Trial to Determine the Efficacy and Safety of Presendin in IIH

Terminated
3
14
Europe, US, RoW
Presendin, Placebo
Invex Therapeutics Ltd., Premier Research Group plc, University Hospitals Birmingham Neuro Ophthalmology Reading Centre, Birmingham, UK, Iowa Visual Field Reading Centre, Iowa, USA
Idiopathic Intracranial Hypertension
09/23
10/23
liMeliGhT, NCT06388200: A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa

Recruiting
3
150
US
Sub-Retinal Administration of OCU400-301
Ocugen
Retinitis Pigmentosa
06/25
10/26
NAC Attack, NCT05537220: Oral N-acetylcysteine for Retinitis Pigmentosa

Recruiting
3
438
Europe, Canada, US, RoW
N-acetylcysteine, Placebo
Johns Hopkins University, National Eye Institute (NEI), Duke University, Emory University, Massachusetts Eye and Ear Infirmary, Mayo Clinic, Medical College of Wisconsin, Retina Foundation of the Southwest, Stanford University, University of California, Davis, University of Florida, University of Iowa, University of Miami, University of Michigan, University of Minnesota, University of Oklahoma, University of Southern California, University of Utah, University of Washington, University of Wisconsin, Madison, Vanderbilt University, Vitreo Retinal Associates, PA, University of Houston, Medical University of Graz, McGill University, Universität Tübingen, Centro Medico ABC, Radboud University Medical Center, University of Amsterdam, University Hospital, Basel, Switzerland, University College London Hospitals, Northwestern University, University of Pennsylvania
Retinitis Pigmentosa
12/28
12/28
TEASE, NCT02402660: Phase 2 Tolerability and Effects of ALK-001 on Stargardt Disease

Recruiting
2
140
US
ALK-001, C20-D3-Retinyl Acetate, C20 Deuterated vitamin A, Placebo
Alkeus Pharmaceuticals, Inc.
Stargardt Disease, Stargardt Macular Degeneration, Stargardt Macular Dystrophy, Autosomal Recessive Stargardt Disease 1 (ABCA4-related)
12/24
03/25
PRODYGY, NCT05748873: Promising ROd-cone DYstrophy Gene TherapY

Recruiting
1/2
33
Europe, US
SPVN06
SparingVision
Retinitis Pigmentosa
03/25
03/29
LIGHTHOUSE, NCT05878860: ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

Recruiting
1/2
21
US
ATSN-201
Atsena Therapeutics Inc.
X-linked Retinoschisis
10/25
10/29
NCT02161380: Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy

Active, not recruiting
1
28
US
injection of scAAV2-P1ND4v2 1.18x10e9 vg (Low),, AAV-ND4, injection of scAAV2-P1ND4v2 5.81 X10e9 vg (Med), injection of scAAV2-P1ND4v2 2.4 X10e10vg (High), injection of scAAV2-P1ND4v2 1.0 X10e11vg (Higher)
Byron Lam, National Eye Institute (NEI)
Leber's Hereditary Optic Neuropathy
03/23
03/25
Platypus, NCT05902962: SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects

Recruiting
1
20
US
VP-001
PYC Therapeutics
Retinal Dystrophy, PRPF31 Mutationassociated Retinal Dystrophy, RP11
05/24
05/24
NCT05294978: EyeConic: Qualification for Cone-Optogenetics

Recruiting
N/A
1000
Europe, US, RoW
Optical coherence tomography (OCT)
University Hospital, Basel, Switzerland, Institute of Molecular and Clinical Ophthalmology Basel
Retinal Dystrophies
12/24
12/25
NCT06140329: Natural History of Autosomal Dominant Optic Atrophy (ADOA), Caused by OPA1 Mutation

Recruiting
N/A
40
Europe, US, RoW
PYC Therapeutics
Autosomal Dominant Optic Atrophy, Optic Atrophy, Autosomal Dominant, Optic Atrophies, Hereditary, Kjer Optic Atrophy
03/26
06/26
POLARIS, NCT06435000: An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene

Recruiting
N/A
75
Europe, US
Splice Bio
Stargardt, Stargardt's Disease, Stargardt Disease, STGD1
12/26
02/27
PRIMA-FS-US, NCT03392324: PRIMA US-Feasibility Study in Atrophic Dry AMD

Active, not recruiting
N/A
5
US
PRIMA
Science Corporation, Pixium Vision LLC acts as sponosor in the US on behalf of Pixium Vision SA
Dry Age-related Macular Degeneration
12/25
12/25
Uni-Rare, NCT05589714: Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

Recruiting
N/A
1500
Europe, Canada, US, RoW
Jaeb Center for Health Research, Foundation Fighting Blindness
Inherited Retinal Degeneration, Retinitis Pigmentosa
12/28
12/28
NCT05218928: Qualification for Cone-Optogenetics

Recruiting
N/A
1000
Europe, US, RoW
OCT
University Hospital, Basel, Switzerland, Institute of Molecular and Clinical Ophthalmology Basel, Switzerland
Retinal Dystrophies
04/22
12/22
Tran, Van ANn
ABNCoV2-03, NCT05329220 / 2021-005504-36: ABNCoV2 Vaccine in Adult Subjects Previously Vaccinated for SARS-CoV-2

Completed
3
4223
Europe, US
ABNCoV2, Comirnaty
Bavarian Nordic
COVID-19 Disease
03/23
10/23
RSV OA=ADJ=012, NCT06534892: An Extension and Crossover Vaccination Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 60 Years of Age and Above Who Participated in RSV OA=ADJ-006 Study

Recruiting
3
12000
Europe, Canada, Japan, US, RoW
RSVPreF3 OA vaccine
GlaxoSmithKline
Respiratory Syncytial Virus Infections
09/26
09/26
SWEET, NCT06214221: Using Signos mHealth Platform in Adults for Weight Management

Active, not recruiting
N/A
380
US
Signos System, Standard Lifestyle Education
Signos Inc, Lindus Health, Inc.
Overweight and Obesity, Metabolic Syndrome, Weight Loss
12/24
04/26
NCT05969756: Early Treatments for Preventing Occlusal Caries Lesions

Active, not recruiting
N/A
114
RoW
Fluoride varnish, 3M™ Clinpro™ White Varnish, Conventional etch and rinse sealant, 3M™ Clinpro™ Sealant, Self-etch sealant, S-PRG filler-containing resin sealant, Beautisealant
Hue University of Medicine and Pharmacy
Caries; Initial, Occlusal Caries, Caries,Dental
10/24
10/24
Leveille, Lynn
NCT05890027: Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation

Recruiting
4
30
US
Phenylephrine Ophthalmic, Eyelid Tape
University of Miami
Ptosis, Eyelid
03/25
03/25

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