| Bertolet, Barry |
VICTORION-2P, NCT05030428: Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease |
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| Active, not recruiting | 3 | 17006 | Europe, Canada, Japan, US, RoW | Inclisiran sodium 300 mg, Placebo | Novartis Pharmaceuticals | Atherosclerotic Cardiovascular Disease | 10/27 | 10/27 | | |
| Recruiting | 3 | 14000 | Europe, Canada, US, RoW | Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL, KJX839, Placebo in 1.5ml | Novartis Pharmaceuticals | Primary Prevention of Atherosclerotic Cardiovascular Disease | 04/29 | 04/29 | | |
NCT05562934: An Efficacy, Safety, Tolerability and Dose Finding Study of XXB750 in Resistant Hypertension Patients. |
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| Active, not recruiting | 2 | 192 | Europe, Japan, US, RoW | Experimental drug, Placebo | Novartis Pharmaceuticals | Resistant Hypertension | 07/24 | 08/24 | | |
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN |
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| Recruiting | N/A | 1400 | Europe, US, RoW | Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation | Medtronic Vascular | Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus | 11/26 | 11/29 | | |
| Active, not recruiting | N/A | 75 | US | Intravascular Lithotripsy | Shockwave Medical, Inc. | Peripheral Arterial Disease | 04/24 | 04/25 | | |
| Recruiting | N/A | 900 | US | Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download, Medication intervention | Medtronic Cardiac Rhythm and Heart Failure | Heart Failure NYHA Class II, Heart Failure NYHA Class III | 04/25 | 04/25 | | |
| Recruiting | N/A | 492 | US | Sirolimus Drug Coated Balloon, Plan balloon Angioplasty (POBA) | Concept Medical Inc., Cardiovascular Research Foundation, New York | In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease | 09/25 | 02/28 | | |
LUX-Dx TRENDS, NCT04790344: Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System. |
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| Active, not recruiting | N/A | 525 | US | Investigational LUX-Dx ICM Implant | Boston Scientific Corporation | Heart Failure | 05/26 | 06/26 | | |
| Latib, Azeem |
SCOUT-II, NCT03225612: Safety and Performance of the Trialign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) |
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| Recruiting | N/A | 60 | Europe | Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) | Mitralign, Inc., Genae, Regulatory and Clinical Research Institute Inc, CardioVascular Research Foundation, Korea | Chronic Symptomatic Functional Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Heart Valve Disease | 06/18 | 11/22 | | |
CorCinch-HFrEF, NCT03533517: Early Feasibility Evaluation of the AccuCinch® Ventricular Restoration System in Patients With Heart Failure and Reduced Ejection Fraction |
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| Active, not recruiting | N/A | 22 | US | AccuCinch® Ventricular Restoration | Ancora Heart, Inc. | Heart Failure, Cardiomyopathy, Dilated | 03/21 | 07/26 | | |
NCT03130491: European Study Evaluating the EMBLOK Embolic Protection System During TAVR |
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| Completed | N/A | 28 | Europe | Transcatheter Aortic Valve Replacement (TAVR), EMBLOK filter | Innovative Cardiovascular Solutions, Meditrial Europe Ltd. | Aortic Valve Disease | 11/21 | 01/22 | | |
| Active, not recruiting | N/A | 572 | Europe, Canada, US | TriClipTM Device | Abbott Medical Devices | Tricuspid Regurgitation | 11/22 | 04/29 | | |
NCT04029337: An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System |
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| Recruiting | N/A | 30 | US | Transcatheter Mitral Valve Replacement | HighLife SAS | Mitral Regurgitation | 12/24 | 12/27 | | |
| Recruiting | N/A | 330571 | US | | Montefiore Medical Center | Valvular Heart Disease | 08/24 | 08/24 | | |
NCT05913908: EFS of the DUO System for Tricuspid Regurgitation (TANDEM II) |
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| Recruiting | N/A | 15 | US | DUO Transcatheter Tricuspid Coaptation Valve System, DUO System | CroiValve Limited | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases | 04/25 | 10/29 | | |
| Recruiting | N/A | 15 | US | Intrepid™ TTVR System | Medtronic Cardiovascular | Tricuspid Regurgitation | 07/25 | 07/31 | | |
NCT04343313: The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study |
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| Recruiting | N/A | 30 | US | Half Moon TMVr System | Half Moon Medical | Mitral Valve Insufficiency | 12/24 | 12/29 | | |
| Recruiting | N/A | 590 | Europe, RoW | Navitor Transcatheter Aortic Valve and FlexNav Delivery System | Abbott Medical Devices | Symptomatic Severe Aortic Stenosis | 06/25 | 02/36 | | |
| Recruiting | N/A | 492 | US | Sirolimus Drug Coated Balloon, Plan balloon Angioplasty (POBA) | Concept Medical Inc., Cardiovascular Research Foundation, New York | In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease | 09/25 | 02/28 | | |
NCT04100720: Early Feasibility Study of the Cardiovalve System for Tricuspid Regurgitation |
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| Not yet recruiting | N/A | 15 | US | Cardiovalve Transfemoral Tricuspid Valve | Boston Biomedical Associates, Cardiovalve Ltd., Cardiovascular Research Foundation, New York | Tricuspid Regurgitation | 12/25 | 12/30 | | |
| Enrolling by invitation | N/A | 300 | Europe, Canada, US | Transcatheter Tricuspid Valve Replacement | Montefiore Medical Center, The Cleveland Clinic, University of Toronto, University Hospital, Bordeaux | Tricuspid Regurgitation | 08/26 | 08/27 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
ENVISION, NCT05932615: IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation |
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| Recruiting | N/A | 1500 | US | Navitor Transcatheter Aortic Valve Implantation (TAVI) System, Any Commercially Available Transcatheter Aortic Valve (CAV) System | Abbott Medical Devices | Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder | 04/27 | 04/36 | | |
PRIME-MR, NCT05332782: Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry |
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| Recruiting | N/A | 2000 | Europe, US | | Universitätsklinikum Hamburg-Eppendorf | Mitral Regurgitation | 01/25 | 01/26 | | |
| Persaud, Nadia |
| Recruiting | 4 | 20000 | US | Atorvastatin 40 Mg Oral Tablet, Lipitor, Placebo oral tablet | Duke University, National Institute on Aging (NIA), National Heart, Lung, and Blood Institute (NHLBI), Wake Forest University Health Sciences | Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases | 12/26 | 12/26 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure With Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 06/24 | 12/30 | | |
| Booth, Kara |
| Completed | N/A | 15 | US | PerQseal Plus Device, Vascular Closure Device | Vivasure Medical Limited | Percutaneous Large Hole Vascular Closure | 07/22 | 07/22 | | |
| Active, not recruiting | N/A | 572 | Europe, Canada, US | TriClipTM Device | Abbott Medical Devices | Tricuspid Regurgitation | 11/22 | 04/29 | | |
| Active, not recruiting | N/A | 15 | US | DurAVRTM THV System | Anteris Technologies Ltd. | Aortic Stenosis, Symptomatic Aortic Stenosis, Severe Aortic Valve Stenosis, Aortic Valve Calcification | 12/23 | 12/33 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Recruiting | N/A | 25 | US | J-Valve TF System | JC Medical, Inc. | Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Regurgitation | 03/24 | 06/29 | | |
| Recruiting | N/A | 30 | Canada, US | Cephea Mitral Valve System | Abbott Medical Devices | Mitral Regurgitation | 06/24 | 06/29 | | |
NCT05913908: EFS of the DUO System for Tricuspid Regurgitation (TANDEM II) |
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| Recruiting | N/A | 15 | US | DUO Transcatheter Tricuspid Coaptation Valve System, DUO System | CroiValve Limited | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases | 04/25 | 10/29 | | |
NCT05666713: NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial |
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| Recruiting | N/A | 150 | US | TELLTALE BASILICA procedure | National Heart, Lung, and Blood Institute (NHLBI) | Valvular Heart Disease, Aortic Valve Failure | 01/25 | 03/25 | | |
| Kobayashi, Yuhei |
| Recruiting | N/A | 500 | US | Coroventis Coroflow Cardiovascular System and PressureWire™ X Guidewire, Acetylcholine Provocation | Yale University, Abbott | Ischemia and No Obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction, Coronary Vasospasm, Endothelial Dysfunction, Microvascular Angina, Chest Pain With Normal Coronary Angiography | 07/24 | 07/29 | | |
| Novelli, Dominic |
| Active, not recruiting | N/A | 572 | Europe, Canada, US | TriClipTM Device | Abbott Medical Devices | Tricuspid Regurgitation | 11/22 | 04/29 | | |
| Edwards, Donellie |
| Active, not recruiting | N/A | 572 | Europe, Canada, US | TriClipTM Device | Abbott Medical Devices | Tricuspid Regurgitation | 11/22 | 04/29 | | |
