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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Depenbusch, Reinhard
ADAPTlate, NCT04565054 / 2019-001488-60: Adjuvant Therapy With Abemaciclib + SOC ET vs. SOC ET in Clinical or Genomic High Risk, HR+/HER2- EBC	Recruiting	3	1260	Europe	Abemaciclib 50 MG; 150mg 1-0-1 per os, Verzenios	West German Study Group, Eli Lilly and Company, Genomic Health®, Inc.	Breast Cancer Female	08/26	03/28
ADAPTcycle, NCT04055493: Adj. Marker-adjusted Personalized Therapy Comparing ET+Ribociclib vs Chemotherapy in Intermediate Risk, HR+/HER2- EBC	Active, not recruiting	3	1684	Europe	Ribociclib 200Mg Oral Tablet, Kisqali	West German Study Group, Novartis, Genomic Health®, Inc.	Breast Cancer Female	07/27	07/27
ADAPTHER2-IV, NCT05704829: NeoAdjuvant Therapy With Trastuzumab-deruxtecan Versus Chemotherapy+Trastuzumab+Pertuzumab in HER2+ Early Breast Cancer	Recruiting	2	402	Europe	Trastuzumab deruxtecan, ENHERTU, Standard-of-Care, Chemotherapy+T+P	West German Study Group, AstraZeneca	HER2-positive Early Breast Cancer	06/26	06/28