La Paz Trials - LARVOL Sigma

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Feliu, Jaime

ASPIRE, NCT05254171: Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

Recruiting

2/3

600

Europe, US, RoW

SBP-101, ivospemin, Nab-paclitaxel, Abraxane, Gemcitabine, Gemzar, Placebo

Panbela Therapeutics, Inc.

Pancreatic Cancer Metastatic, Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Stage IV

08/26

01/27

IMC-C103C-101, NCT03973333: Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab

Withdrawn

1/2

Europe, US

IMC-C103C, Atezolizumab, TECENTRIQ

Immunocore Ltd

Select Advanced Solid Tumors

09/23

PAUF, NCT05141149 / 2021-000682-32: First in Human Phase1/2a Clinical Trial of Anti- Monoclonal Antibody PBP1510 in Patients With Pancreatic Cancer

Recruiting

1/2

Europe, US, RoW

PBP1510 (400mg/16mL), Gemcitabine (1000 mg/m^2)

Prestige Biopharma Limited, Prestige Biopharma Limited

Pancreatic Cancer

02/26

12/26

CHEMOFAST, NCT04247464: Short-term Fasting as an Enhancer of Chemotherapy: Pilot Clinical Study on Colorectal Carcinoma Patients

Completed

N/A

Europe

Fasting

IMDEA Food, Hospital Infanta Sofia, Hospital Universitario La Paz

Fasting

02/23

Moreno, Raul

NCT03613246: NVT ALLEGRA TAVI System TF in Failing Calcified Aortic Heart Valves in a Real-world Patient Population

Active, not recruiting

N/A

346

Europe

NVT GmbH

Transcatheter Aortic Valve Implantation

12/24

01/29

NCT06588634: The PERSEVERE Study

Recruiting

N/A

200

Europe, US

FlowTriever System, Standard of Care

Inari Medical

Pulmonary Embolism, Pulmonary Thromboembolism

12/26

08/27

FAST III, NCT04931771: Fractional Flow Reserve or 3D-Quantitative-Coronary-Angiography Based Vessel-FFR Guided Revascularization

Recruiting

N/A

2228

Europe

vFFR guided revascularization, FFR guided revascularization

ECRI bv, Siemens Healthineers AG, Pie Medical Imaging

Coronary Artery Disease

05/25

Trevisio PAS, NCT04433520: Trevisio Post-Approval Study

Active, not recruiting

N/A

251

Europe

Amplatzer™ Trevisio™ Intravascular Delivery System using Amplatzer PFO Occluder, ASO or Amplatzer Cribriform Occluder, Amplatzer™ Trevisio™ Intravascular Delivery System using Amplatzer Muscular VSD Occluder or Amplatzer Post-Infarct Muscular VSD Occluder

Abbott Medical Devices

PFO - Patent Foramen Ovale, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PIVSD - Post Infarct Muscular Ventricular Septal Defect

09/25

10/25

EMPIRE-II, NCT05804903: Investigation of the NVT ALLEGRA Plus THV System in Patients With Severe Aortic Stenosis or Failed Surgical Aortic Bioprosthesis

Recruiting

N/A

177

Europe

(ALLEGRA Plus Transcatheter Heart Valve) TAVI in severe calcified aortic stenosis or in failed surgical aortic bioprosthesis

NVT GmbH

Transcatheter Aortic Valve Implantation

03/25

12/29

NCT05114850: Retrospective Prospective Multicentric Clinical Follow up of Patients After Being Treated With TricValve®

Recruiting

N/A

450

Europe

P+F Products + Features GmbH

Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Insufficiency, Heart Failure, Heart Diseases, Heart Valve Diseases

12/25

12/28

AV-MDR, NCT04573660: Abbott Vascular Medical Device Registry

Recruiting

N/A

3784

Europe, US, RoW

Coronary and peripheral stents, Pacing catheters, Vascular plugs, Measurement and imaging (FFR and OCT), Peripheral dilatation catheters, Coronary dilatation catheters, Coronary and peripheral guidewires, Vessel closure/compression devices, Vascular access introducers

Abbott Medical Devices

Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism, Arterial Embolism

11/30

11/31

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Feliu, Jaime

ASPIRE, NCT05254171: Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

Recruiting

2/3

600

Europe, US, RoW

SBP-101, ivospemin, Nab-paclitaxel, Abraxane, Gemcitabine, Gemzar, Placebo

Panbela Therapeutics, Inc.

Pancreatic Cancer Metastatic, Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Stage IV

08/26

01/27

IMC-C103C-101, NCT03973333: Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab

Withdrawn

1/2

Europe, US

IMC-C103C, Atezolizumab, TECENTRIQ

Immunocore Ltd

Select Advanced Solid Tumors

09/23

PAUF, NCT05141149 / 2021-000682-32: First in Human Phase1/2a Clinical Trial of Anti- Monoclonal Antibody PBP1510 in Patients With Pancreatic Cancer

Recruiting

1/2

Europe, US, RoW

PBP1510 (400mg/16mL), Gemcitabine (1000 mg/m^2)

Prestige Biopharma Limited, Prestige Biopharma Limited

Pancreatic Cancer

02/26

12/26

CHEMOFAST, NCT04247464: Short-term Fasting as an Enhancer of Chemotherapy: Pilot Clinical Study on Colorectal Carcinoma Patients

Completed

N/A

Europe

Fasting

IMDEA Food, Hospital Infanta Sofia, Hospital Universitario La Paz

Fasting

02/23

Moreno, Raul

NCT03613246: NVT ALLEGRA TAVI System TF in Failing Calcified Aortic Heart Valves in a Real-world Patient Population

Active, not recruiting

N/A

346

Europe

NVT GmbH

Transcatheter Aortic Valve Implantation

12/24

01/29

NCT06588634: The PERSEVERE Study

Recruiting

N/A

200

Europe, US

FlowTriever System, Standard of Care

Inari Medical

Pulmonary Embolism, Pulmonary Thromboembolism

12/26

08/27

FAST III, NCT04931771: Fractional Flow Reserve or 3D-Quantitative-Coronary-Angiography Based Vessel-FFR Guided Revascularization

Recruiting

N/A

2228

Europe

vFFR guided revascularization, FFR guided revascularization

ECRI bv, Siemens Healthineers AG, Pie Medical Imaging

Coronary Artery Disease

05/25

Trevisio PAS, NCT04433520: Trevisio Post-Approval Study

Active, not recruiting

N/A

251

Europe

Abbott Medical Devices

PFO - Patent Foramen Ovale, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PIVSD - Post Infarct Muscular Ventricular Septal Defect

09/25

10/25

EMPIRE-II, NCT05804903: Investigation of the NVT ALLEGRA Plus THV System in Patients With Severe Aortic Stenosis or Failed Surgical Aortic Bioprosthesis

Recruiting

N/A

177

Europe

(ALLEGRA Plus Transcatheter Heart Valve) TAVI in severe calcified aortic stenosis or in failed surgical aortic bioprosthesis

NVT GmbH

Transcatheter Aortic Valve Implantation

03/25

12/29

NCT05114850: Retrospective Prospective Multicentric Clinical Follow up of Patients After Being Treated With TricValve®

Recruiting

N/A

450

Europe

P+F Products + Features GmbH

Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Insufficiency, Heart Failure, Heart Diseases, Heart Valve Diseases

12/25

12/28

AV-MDR, NCT04573660: Abbott Vascular Medical Device Registry

Recruiting

N/A

3784

Europe, US, RoW

Abbott Medical Devices

Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism, Arterial Embolism

11/30

11/31



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