Milton Keynes University Hospital
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 6 Trials 
24 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Mukherjee, Somnath
SCOPE2, NCT02741856 / 2015-001740-11: Study of Chemoradiotherapy in Oesophageal Cancer Including PET Response and Dose Escalation

Recruiting
2/3
584
Europe
Carboplatin, Paclitaxel, Cisplatin, Capecitabine, Radiotherapy
Lisette Nixon, Cancer Research UK
Oesophageal Cancer
04/21
04/23
Stewart, Richard B
REMAP-CAP, NCT02735707 / 2015-002340-14: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Recruiting
3
20000
Europe, Canada, Japan, US, RoW
Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, IFN-β1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, acetylsalicylic acid, P2Y12 inhibitor, Clopidogrel, Prasugrel, Ticagrelor, No simvastatin, Simvastatin, Placebo, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Ramipril, Lisinopril, Perindopril, Enalapril, Trandolapril, Captopril, Angiotensin Receptor Blockers, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Paxlovid, Remdesivir, Nirmatrelvir/ritonavir + remdesivir
UMC Utrecht, Australian and New Zealand Intensive Care Research Centre, Medical Research Institute of New Zealand, Unity Health, Berry Consultants, Global Coalition for Adaptive Research, University of Pittsburgh Medical Center, Intensive Care National Audit & Research Centre, St. Marianna University School of Medicine, National Intensive Care Surveillance MORU, National University Hospital, Singapore
Community-acquired Pneumonia, Influenza, COVID-19
02/26
02/28
Keeler, Barrie D
VOLCANO, NCT05262296: Versius Or Laparoscopic Colorectal Cancer and Non-cancer Operation Outcomes

Recruiting
N/A
60
Europe
Laparoscopic Surgeon, Robotic Arm
Joanne Turner
Colorectal Disorders
09/25
09/25
VOLTAIRE, NCT05262374: Versius Or Laparoscopic TransAbdominal Inguinal Hernia REpair

Recruiting
N/A
60
Europe
Procedure/Surgery: Laparoscopic, Robotic
Joanne Turner
Inguinal Hernia
03/24
03/24
VOLARE, NCT05253586: Versius Or Laparoscopic Abdominal Hernia REpair

Not yet recruiting
N/A
60
NA
Laparoscopic, Robotic
Joanne Turner
Abdominal Hernia, Abdominal Surgery
03/24
03/24
Williams, Felicity
PROTEUS, NCT05028179: Evaluating the Use of Artificial Intelligence to Support Stress Echocardiography Testing for Heart Disease

Active, not recruiting
N/A
2338
Europe
EchoGo
Ultromics Ltd, University of Oxford, Academic Health Science Centres, National Institute for Health Research, United Kingdom
Coronary Heart Disease
06/23
12/23
Eldeeb, Hany
POETIC-A, NCT04584853 / 2019-003897-24: PreOperative Endocrine Therapy for Individualised Care With Abemaciclib

Recruiting
3
2032
Europe
Abemaciclib, Verzenios, Endocrine therapy (letrozole, anastrozole, exemestane or tamoxifen), Arimidex, Aromasin, Femara, or Tamoxifen
Institute of Cancer Research, United Kingdom
Breast Cancer Female
09/30
03/32
Cleator, Susan
POETIC-A, NCT04584853 / 2019-003897-24: PreOperative Endocrine Therapy for Individualised Care With Abemaciclib

Recruiting
3
2032
Europe
Abemaciclib, Verzenios, Endocrine therapy (letrozole, anastrozole, exemestane or tamoxifen), Arimidex, Aromasin, Femara, or Tamoxifen
Institute of Cancer Research, United Kingdom
Breast Cancer Female
09/30
03/32
PEAR-MET, NCT06182306: Prospective Evaluation of AI R&D Tool for Patient Stratification - MoA Evaluation in Triple Negative Breast Cancer

Recruiting
N/A
30
Europe
Biopsy
Ourotech, Inc., Guys' and St. Thomas Hospital, Barts & The London NHS Trust, Imperial College Healthcare NHS Trust, Nottingham University Hospitals Trust, Hampshire Hospitals NHS Foundation Trust
Breast Cancer, Triple Negative Breast Cancer
09/25
06/26
Kardos, Attila
VECTRA, NCT03498105: Utility of the Cardiac Electrical BiomarkerDisease

Recruiting
N/A
800
Europe
Joanne Turner
Acute Chest Syndrome
06/23
06/23
PROTEUS, NCT05028179: Evaluating the Use of Artificial Intelligence to Support Stress Echocardiography Testing for Heart Disease

Active, not recruiting
N/A
2338
Europe
EchoGo
Ultromics Ltd, University of Oxford, Academic Health Science Centres, National Institute for Health Research, United Kingdom
Coronary Heart Disease
06/23
12/23
BIO|STREAM HF, NCT03366545: Observation of Clinical Routine Care for Heart Failure Patients Implanted With BIOTRONIK CRT Devices

Recruiting
N/A
3000
Europe, Japan, RoW
Cardiac Resynchronization Therapy (CRT)
Biotronik SE & Co. KG
Heart Failure
12/24
06/25
Dungarwalla, Moez
BRUIN CLL-321, NCT04666038: Study of LOXO-305 Versus Investigator's Choice (IdelaR or BR) in Patients With Previously Treated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Active, not recruiting
3
250
Europe, Canada, Japan, US, RoW
LOXO-305, Pirtobrutinib, Idelalisib, Zydelig, Bendamustine, Treanda, Treakisym, Ribomustin, Levact, Rituximab, Rituxan, MabThera, Truxima
Loxo Oncology, Inc., Eli Lilly and Company
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
11/23
05/27
ACCoRd, NCT03562169: The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII

Recruiting
3
406
Europe
Ixazomib, thalidomide, & dexamethasone (ITD) re-induction, Conventional autologous stem cell transplant (ASCT-con), Augmented autologous stem cell transplant (ASCT-aug), ITD consolidation and ixazomib maintenance vs. No further therapy
University of Leeds, Cancer Research UK, Takeda
Multiple Myeloma
03/26
03/27
iinnovate-1, NCT03215030: A Study of Modakafusp Alfa on Adult Participants With Relapsed/Refractory Multiple Myeloma

Active, not recruiting
1/2
336
Europe, Canada, Japan, US, RoW
Modakafusp alfa, TAK-573, TEV-48573, Dexamethasone
Takeda
Multiple Myeloma
02/24
09/24
Gulati, Divyansh
DAShED, NCT05582967: The (Diagnosis of Aortic Syndrome in the ED) Study

Completed
N/A
5548
Europe
Completion of focused Electronic Case Report Form
NHS Lothian, University of Edinburgh
Aortic Dissection
01/23
01/23
STEDI2, NCT05427838: Simulation Training in Emergency Department Imaging 2

Recruiting
N/A
294
Europe
Oxford University Hospitals NHS Trust
Skull Fractures, Stroke, Intracranial Bleed, Brain Tumor, Brain Herniation
10/24
06/25
Madhotra, Ravi
RECEDE, NCT04516785: Reducing Colonoscopies in Patients Without Significant Bowel Disease

Completed
N/A
1181
Europe
FIT and VOC
University Hospitals Coventry and Warwickshire NHS Trust, University of Warwick, University of Leeds, University of Manchester
Colorectal Cancer, Colorectal Disorders, Colorectal Adenoma, Colorectal Polyp
11/22
11/22
Scalletta, Diane
RECEDE, NCT04516785: Reducing Colonoscopies in Patients Without Significant Bowel Disease

Completed
N/A
1181
Europe
FIT and VOC
University Hospitals Coventry and Warwickshire NHS Trust, University of Warwick, University of Leeds, University of Manchester
Colorectal Cancer, Colorectal Disorders, Colorectal Adenoma, Colorectal Polyp
11/22
11/22
Mew, Louise
YOUNG HIP, NCT04660149: An Exploration Into the Young Patients' (< 50 Years) Expectations Following Primary Total Hip Arthroplasty

Completed
N/A
10
Europe
Bournemouth University
Total Hip Replacements
04/23
04/23
Triscott, Simon
STEDI2, NCT05427838: Simulation Training in Emergency Department Imaging 2

Recruiting
N/A
294
Europe
Oxford University Hospitals NHS Trust
Skull Fractures, Stroke, Intracranial Bleed, Brain Tumor, Brain Herniation
10/24
06/25
Colda, Antoanela
VOLCANO, NCT05262296: Versius Or Laparoscopic Colorectal Cancer and Non-cancer Operation Outcomes

Recruiting
N/A
60
Europe
Laparoscopic Surgeon, Robotic Arm
Joanne Turner
Colorectal Disorders
09/25
09/25
Patil, Veeresh
CLEAR, NCT04140214 / 2017-000664-14: Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis

Recruiting
3
288
Europe
Hypertonic saline, MucoClear 6%, HTS, Carbocysteine 750 MG, Mucodyne
Belfast Health and Social Care Trust, Queen's University, Belfast
Bronchiectasis
09/24
09/24
Babu, Reema Alen
CLEAR, NCT04140214 / 2017-000664-14: Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis

Recruiting
3
288
Europe
Hypertonic saline, MucoClear 6%, HTS, Carbocysteine 750 MG, Mucodyne
Belfast Health and Social Care Trust, Queen's University, Belfast
Bronchiectasis
09/24
09/24

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