The 1st Affiliated Hospital, Sun Yet-sen University
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 138 Trials 
186 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Chen, Jianghua
NCT03902691: Study of the Efficacy and Safety of Pegol-Sihematide for Anemia in Patients With Chronic Kidney Disease on Dialysis

Completed
3
372
RoW
Pegol-Sihematide, ESPO
Jiangsu Hansoh Pharmaceutical Co., Ltd.
Chronic Kidney Diseases
02/21
05/22
NCT05629598: A Study of PEG-EPO Injection (CHO Cells) for Maintenance Therapy of Patients With Renal Anemia .

Recruiting
2
150
RoW
Recombinant human erythropoietin injection, Human erythropoietin injection
Angde Biotech Pharmaceutical Co., Ltd.
Renal Anemia
03/23
08/23
NCT05687890: A Study to Evaluate the Efficacy and Safety of SC0062 in the Treatment of Chronic Kidney Disease

Active, not recruiting
2
255
RoW
Placebo of SC0062, SC0062 low dose, SC0062 medium dose, SC0062 high dose
Biocity Biopharmaceutics Co., Ltd.
Diabetic Kidney Disease, IgA Nephropathy
11/24
04/25
TESTING-ON, NCT05434325: TESTING -ON Post-Trial ObservatioNal Cohort Study

Recruiting
N/A
366
Canada, RoW
The George Institute, Peking University Institute of Nephrology
IgA Nephropathy, ESRD, Glomerulonephritis, Kidney Diseases
07/27
07/27
Shi, Wei
Oxycodone, NCT06690307: Versus Sufentanil in Patient-controlled Intravenous Analgesia After Laparoscopic Hysterectomy

Recruiting
4
64
RoW
patient controlled intravenous analgesia(PCIA)
Affiliated Hospital of Nantong University
Laparoscopic Hysterectomy
12/25
07/26
CAPSTONE-1, NCT03711305: Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)

Active, not recruiting
3
462
RoW
SHR-1316, Carboplatin, Etoposide, Placebo
Jiangsu HengRui Medicine Co., Ltd.
Extensive-stage Small Cell Lung Cancer
10/22
12/23
PYRAMID-1, NCT04447118 / 2020-000951-11: Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy

Active, not recruiting
3
151
Europe, US, RoW
Pyrotinib, Irene, Docetaxel, Docetaxel injection
Jiangsu HengRui Medicine Co., Ltd.
Non-squamous NSCLC, HER2 Exon 20 Mutation
06/23
10/23
TQ05105-III-01, NCT06682169: Evaluation of Rovadicitinib Compared to the Protocol Selected by Researchers in Third Line and Subsequent Studies of Moderate to Severe Chronic Graft-versus-host Disease

Recruiting
3
182
RoW
Rovadicitinib, Imatinib, Methotrexate, Mycophenolate mofetil, Rituximab
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Graft-versus-host Disease
10/29
12/30
NCT05674539: Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Recruiting
3
200
RoW
Fludarabine and Busulfan, Fludara and Busulfex, Fludarabine and Melphalan, Busulfex and Fludara
Wuhan Union Hospital, China
Acute Myeloid Leukemia, Adult, Myelodysplastic Syndrome(MDS), Allogeneic Hematopoietic Stem Cell Transplantation
01/25
06/25
NCT03085069: A Study to Evaluate SHR-1210 in Patients With Advanced or Metastatic NSCLC

Active, not recruiting
2
146
RoW
SHR-1210
Jiangsu HengRui Medicine Co., Ltd.
Lung Neoplasms, Carcinoma, Non-Small-Cell Lung, Respiratory Tract Neoplasms Nec, Lung Disease, Respiratory Tract Disease, Neoplasm, Bronchial, Carcinoma, Bronchogenic
08/20
08/23
NCT02958020: Multicenter Cohort Study on Osteoporosis

Recruiting
N/A
50000
RoW
Shanghai University of Traditional Chinese Medicine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Dongzhimen Hospital, Beijing, The First Affiliated Hospital of Guangzhou University of TCM, Guangdong Provincial Hospital of Traditional Chinese Medicine, Affiliated Hospital of Changchun University of Chinese Medicine, Gansu Provincial Hospital, Guangzhou Kingmed Diagnostics Co., Ltd., Shandong Provincial Hospital of Traditional Chinese Medicine, Yunnan Provincial Hospital of Traditional Chinese Medicine, Shenzhen Pingle Orthopedic Hospital, First People's Hospital of Nankang District, Ganzhou City
Osteoporosis
10/26
10/28
Yu, Xue Qing
TECAS, NCT03909217: Treating Depression With Transcutaneous Electrical Cranial-auricular Acupoint Stimulation ().

Completed
2/3
470
RoW
TECAS Procedure, TECAS, Escitalopram, Escitalopram Oxalate Tablets, Insomnia medication, Benzo
The University of Hong Kong, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing First Hospital of integrated Chinese and Western Medicine, The First Hospital of Hebei Medical University, Southwest Medical University, Hospital of Traditional Chinese Medicine
Mild-to-moderate Depression
07/21
12/21
BHAS, NCT03072797: Beijing Hospital Atherosclerosis Study

Recruiting
N/A
3000
RoW
Beijing Hospital
Atherosclerosis, Cardiovascular Diseases, Coronary Artery Disease, Myocardial Ischemia, Stroke
12/22
12/22
DCB-denovo, NCT04022200: Angioplasty With Paclitaxel-coated Balloon Only Strategy for Coronary de Novo Lesions

Recruiting
N/A
300
RoW
Paclitaxel DCB
Beijing Hospital
Coronary Disease
01/23
07/23
NCT04664439: Follow-up With CT-FFR in CHD Patients After DCB

Recruiting
N/A
92
RoW
CT-FFR
Beijing Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College
Coronary; Ischemic
12/23
06/24
NCT05131191: CT-FFR for Coronary In-stent Stenosis Based on ISR-Net Algorithm

Active, not recruiting
N/A
150
RoW
CT-FFR measurement, FFRCT, invasive FFR, pressure wire
Beijing Hospital
Coronary Stent Occlusion
01/24
06/24
NCT02954419: IgA Nephropathy Biomarkers Evaluation Study (INTEREST)

Recruiting
N/A
2000
RoW
No intervention
Sun Yat-sen University
IgA Nephropathy, Glomerular Diseases
11/26
01/27
Fu, Ping
NCT06597201: Evaluate the Efficacy and Safety of Amino Acid (15) Peritoneal Dialysis Solution in Peritoneal Dialysis Patients with Malnutrition.

Recruiting
4
400
RoW
amino acid (15) peritoneal dialysis solution, glucose peritoneal dialysis solution
Chengdu Qingshan Likang Pharmaceutical Co., Ltd
End Stage Renal Disease (ESRD)
06/25
06/25
ALIGN, NCT04573478: Atrasentan in Patients With IgA Nephropathy

Active, not recruiting
3
404
Europe, Canada, Japan, US, RoW
Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo
Chinook Therapeutics, Inc.
IgA Nephropathy, Immunoglobulin A Nephropathy
12/26
12/26
NCT05593575: Efficacy and Safety of SPH3127 Tablets on Treating the Diabetic Kidney Disease

Recruiting
2
320
RoW
SPH3127+SPH3127matching placebo+valsartan matching placebo, SPH3127+valsartan matching placebo, SPH3127 matching placebo+valsartan
Shanghai Pharmaceuticals Holding Co., Ltd
Diabetic Kidney Disease
06/25
06/25
NCT05328843: Study to Evaluate the Pharmacokinetic Characteristics of Pegylated Exenatide Injection (PB-119) in Subjects With Different Degrees of Renal Insufficiency and Matched Subjects With Normal Renal Function

Not yet recruiting
1
24
RoW
PB119
PegBio Co., Ltd.
Type2Diabetes
10/22
10/22
SCDB, NCT06422845: Peripheral Scoring Drug-coated Balloon in the Treatment of Hemodialysis Arteriovenous Fistula Stenosis

Recruiting
N/A
328
RoW
Dissolve AV Peripheral Scoring Drug-coated Balloon, Scoring Drug-coated Balloon
DK Medical Technology (Suzhou) Co., Ltd.
Arteriovenous Fistula Stenosis
07/27
07/27
TESTING-ON, NCT05434325: TESTING -ON Post-Trial ObservatioNal Cohort Study

Recruiting
N/A
366
Canada, RoW
The George Institute, Peking University Institute of Nephrology
IgA Nephropathy, ESRD, Glomerulonephritis, Kidney Diseases
07/27
07/27
Zhang, Jin li
NCT03359694: Mutation Scores and Differential Protein Evaluating Efficacy in Adjuvant Chemotherapy in HER2(-) Luminal B Breast Cancer

Not yet recruiting
3
300
RoW
DT group, Pegylated liposomal doxorubicin and Docetaxel, ET group, Conventional doxorubicin and Docetaxel, NX group, Navelbine and Xeloda
Tianjin Medical University Cancer Institute and Hospital
Susceptibility, Genetic, Chemotherapy Effect
11/19
10/22
NCT04629846: Study in Participants With Early-Stage or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive and Estrogen Receptor/Progesterone Receptor Negative Breast Cancer to Evaluate the Efficiency and Safety of Treatment With Trastuzumab Plus (+) QL1209/Pertuzumab + Docetaxel.

Completed
3
517
RoW
Trastuzumab, Herceptin®, QL1209, Recombinant anti-HER-2 domain Ⅱ humanized monoclonal antibody injection, Pertuzumab, Perjeta®, Docetaxel, Docetaxel injection, surgery
Qilu Pharmaceutical Co., Ltd.
Breast Cancer
08/22
10/23
CLOVER, NCT03926091: Study Comparing 4 Cycles With 6 Cycles of TC (Docetaxel+Cyclophosphamide) Adjuvant Chemotherapy for 1-3 Lymph Node Positive ER+/HER2- Early Breast Cancer

Recruiting
3
2172
RoW
Docetaxel, docetaxel injection, Cyclophosphamide, Cyclophosphamide injection
Fudan University
Breast Cancer
11/24
11/25
BENCH, NCT04939142: A Study of Evaluating the Safety and Efficacy of ATG-010, Bortezomib, and Dexamethasone (SVd) Versus Bortezomib and Dexamethasone (Vd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM)

Active, not recruiting
3
150
RoW
SVd (Selinexor+Bortezomib+dexamethasone), Vd (Bortezomib+dexamethasone)
Antengene Corporation
Relapsed or Refractory Multiple Myeloma
07/24
10/24
BELIEVE-01, NCT05234684: A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With MCD Subtype Diffuse Large B-cell Lymphoma

Recruiting
3
150
RoW
Orelabrutinib + R-CHOP, ICP-022+ R-CHOP, Placebo + R-CHOP
Beijing InnoCare Pharma Tech Co., Ltd.
Diffuse Large B Cell Lymphoma (DLBCL)
07/24
12/25
NCT04578613: ICP-022 Versus Chlorambucil Combined With Rituximab in the Treatment of Untreated CLL/SLL

Recruiting
3
218
RoW
ICP-022, Chlorambucil, Rituximab
Beijing InnoCare Pharma Tech Co., Ltd.
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
12/24
06/25
NCT03351062: Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast Cancer

Recruiting
3
844
RoW
Tamoxifen, Tamoxifen citrate, Toremifene, fareston
Chinese Anti-Cancer Association, Fudan University, Henan Cancer Hospital, The First Hospital of Jilin University, Southwest Hospital, China, First Hospital of China Medical University, Guangdong Provincial People's Hospital, Harbin Medical University, First Affiliated Hospital of Chongqing Medical University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Jiangsu Provincial People's Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Zhejiang Cancer Hospital, Tianjin Medical University Cancer Institute and Hospital, Union hospital of Fujian Medical University, Hebei Tumor Hospital, Hunan Cancer Hospital, Affiliated Hospital of Qinghai University, Wuhan TongJi Hospital, Hainan People's Hospital, The Third Affiliated Hospital of Kunming Medical College., The Third Affiliated Hospital of Nanchang University
Breast Cancer Female
12/25
12/25
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

Recruiting
3
6000
Europe, Canada, Japan, US, RoW
Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane
Eli Lilly and Company
Breast Neoplasms
10/27
03/32
NCT06227117: Neoadjuvant Study of DV in Combination Toripalimab or Sequence Chemotherapy in HR-negative, HER2 Low-expressing Breast Cancer

Recruiting
2
120
RoW
Disitamab Vedotin Injection (18 weeks), DV,RC48-ADC, Toripalimab (18weeks), JS001, Carboplatin, Disitamab Vedotin Injection (12 weeks), Sequential Epirubicin, Epirubicin, Sequential CTX, CTX, cyclophosphamide, Toripalimab (12weeks)
RemeGen Co., Ltd.
Breast Cancer
12/25
12/26
NCT04562870 / 2020-003809-60: A Study to Evaluate Single Agent Selinexor Versus Physician's Choice in Participants with Previously Treated Myelofibrosis

Hourglass Jul 2023 - Dec 2023 : Top-line data from XPORT-MF-035 trial for myelofibrosis
Checkmark First patient dosed as a monotherapy in patients with 2L myelofibrosis
Dec 2021 - Dec 2021: First patient dosed as a monotherapy in patients with 2L myelofibrosis
Active, not recruiting
2
112
Europe, US, RoW
Selinexor, Physician's Choice Treatment
Karyopharm Therapeutics Inc
Myelofibrosis
01/25
01/25
NCT03955978: TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer

Active, not recruiting
1
10
US
TSR-042, Brachytherapy, Endometrial biopsy, Blood draw for immune response
Washington University School of Medicine, Tesaro, Inc.
Endometrial Cancer, Cancer of the Endometrium
03/24
12/25
ES-CS, NCT04657107: The Efficacy and Safety of S-ketamine in Elective Cesarean Section

Not yet recruiting
N/A
402
NA
S-ketamine, esketamine, normal saline, physiological saline
Beijing Obstetrics and Gynecology Hospital, China Health Promotion Foundation, Beijing Haidian Maternal and Child Health Hospital, Obstetrics & Gynecology Hospital of Fudan University, Fourth Hospital of Shijiazhuang City, Changzhi Maternal and Child Health Hospital, Linfen Maternity&Child Healthcare Hospital, Maternal and Child Health Hospital, Jiading District, Tongzhou Maternal and Child Healthcare Hospital of Beijing, Beijing Chaoyang District Maternal and Child Health Care Hospital
Anesthesia, Analgesia, Depression, Cesarean Section, Parturition
12/21
07/22
NCT04940091: Epidural Analgesia and Maternal Fever During Labor

Recruiting
N/A
780
RoW
Epidural analgesia, No other intervention
Peking University First Hospital, Guangdong Women and Children Hospital, Tangshan Maternal and Child Health Hospital, Dongguan Maternal and Child Health Hospital, Beijing Haidian Maternal and Child Health Hospital, Beijing Fuxing Hospital, Fourth Hospital of Shijiazhuang City, Xiamen Maternity & Child Care Hospital
Epidural Analgesia, Analgesic Effect, Fever
09/22
10/22
NCT04582955: Neoadjuvant Treatment of Early Triple-negative Breast Cancer With Chidamide and Chemotherapy

Recruiting
N/A
20
RoW
Chidamide in combination with chemotherapy, Other Name: For Chidamide: HBI-8000, CS055
Tianjin Medical University Cancer Institute and Hospital
Triple-negative Breast Cancer
12/22
12/22
NCT02506361: Evaluation of the Relationship of TOP2α Expression and Effect of Non Dose-dense Chemotherapy for Breast Cancer

Recruiting
N/A
800
RoW
Tianjin Medical University Cancer Institute and Hospital
Breast Cancer
05/25
10/25
NCT05534854: Frequency, Clinical Phenotype and Genetic Analysis of Heritable Kidney Cancer Syndromes

Recruiting
N/A
500
RoW
Gene test
RenJi Hospital, Ruijin Hospital, Shanghai Zhongshan Hospital, Huashan Hospital, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Zhejiang Provincial People's Hospital, Tongji Hospital, Second Affiliated Hospital, School of Medicine, Zhejiang University, Shanghai 10th People's Hospital, First Affiliated Hospital, Sun Yat-Sen University, Peking University First Hospital
Renal Tumor Histology, Kidney Cancer, Renal Cell Carcinoma, Familial Renal Cancer, HLRCC, VHL Syndrome, BAP1 Tumor Predisposition Syndrome, FLCN Gene Mutation, ALK Gene Mutation, FH Gene Mutation, Birt-Hogg-Dube Syndrome, MET Gene Mutation, Cutaneous Leiomyoma, Cutaneous Leiomyomata With Uterine Leiomyomata
08/25
08/25
Chen, Jian
NCT03521986: Pain and Quality of Life After Mediastinal Tumor Resection by Subxiphoid and Intercostal VATS

Recruiting
3
100
RoW
Subxiphoid uniportal VATS, Intercostal uniportal VATS
Lei Jiang
Mediastinal Neoplasms, Thoracic Neoplasm, Thoracic Surgery
10/23
10/23
NCT03523468: Curative Effect and Quality of Life Between Uniportal and Open Sleeve Lobectomy for Central Type Lung Cancer

Recruiting
3
200
RoW
uniportal sleeve lobectomy, open sleeve lobectomy
Lei Jiang, Shanghai Pulmonary Hospital, Shanghai, China
Video-Assisted Thoracic Surgery, Lung Cancer
05/24
12/24
NCT06205927: Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer

Recruiting
2
77
RoW
Standard carbon ion beam radiotherapy, Carbon ion beam radiotherapy simultaneously dose boost
Jian Chen
Non-small Cell Lung Cancer
12/24
12/26
NCT06186726: Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial Tumors

Recruiting
2
48
RoW
carbon ion radiotherapy
Jian Chen
Carbon Ion Radiotherapy, Thymoma, Thymic Carcinoma, Radiotherapy, Chemotherapy
12/26
12/29
NCT06311981: Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients

Recruiting
2
29
RoW
carbon ion radiotherapy, targeted therapy, single regimen chemotherapy in sequence with radiotherapy
Jian Chen
Non-small Cell Lung Cancer, Older People, Carbon Ion Radiotherapy, Radiotherapy Side Effect
06/25
06/26
NCT06311955: Clinical Study of Postoperative Carbon Ion Radiotherapy for Thymus Tumor With Residual Tumor

Recruiting
2
48
RoW
Carbon ion radiotherapy, combined with platinum-based regimen
Jian Chen
Thymic Epithelial Tumor, Radiotherapy Side Effect, Carbon Ion Radiotheray, Heavy Ion Radiotherapy
02/28
02/29
NCT06311968: The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor

Recruiting
2
55
RoW
Proton radiotherapy, combined platinum based chemotherapy
Jian Chen
Thymus Epithelial Tumor, Proton Radiotherapy, Radiation Toxicity
02/27
02/27
SPH5030-201, NCT06434597: A Clinical Study of SPH5030 Tablets in the Treatment of Her2-positive/Mutated Biliary Tract OR Colorectal Cancer Patients.

Recruiting
2
60
RoW
SPH5030
Shanghai Pharmaceuticals Holding Co., Ltd
Biliary Tract or Colorectal Cancer With Her2-positive/Mutated
12/26
12/26
NCT05613452: Carbon Ion Therapy for Peripheral Non-small Cell Lung Cancer

Recruiting
2
43
RoW
Carbon ion beam radiotherapy
Shanghai Proton and Heavy Ion Center
Non-small Cell Lung Cancer
01/25
01/26
NCT05715931: Perioperative Chemotherapy Plus Trastuzumab Plus Toripalimab in HER2 Positive Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

Recruiting
2
30
RoW
Toripalimab, Trastuzumab, 5-FU, leucovorin, docetaxel, oxaliplatin (FLOT)
Yu jiren
Adenocarcinoma of the Stomach, Adenocarcinoma of Esophagogastric Junction, HER2-positive Gastric Cancer
03/25
03/28
NCT05729646: Perioperative Chemotherapy Plus Toripalimab for dMMR Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

Recruiting
2
90
RoW
Toripalimab, Oxaliplatin, S1
Yu jiren
Adenocarcinoma of the Stomach, Adenocarcinoma of Esophagogastric Junction, Mismatch Repair Deficiency
02/26
02/29
NCT05872685: Perioperative Chemotherapy Combined With Serplulimab or Placebo for pMMR Locally Advanced Gastric Adenocarcinoma (FOCUS-05)

Recruiting
2
314
RoW
S1, Oxaliplatin, Serplulimab, Placebo
Yu jiren
Adenocarcinoma of the Stomach, Adenocarcinoma of Esophagogastric Junction, Proficient Mismatch Repair
04/26
04/29
NCT05970627: Perioperative Chemotherapy Plus Toripalimab for Epstein-Barr Virus-associated Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

Not yet recruiting
2
30
RoW
Toripalimab, Oxaliplatin, S1
Yu jiren
Adenocarcinoma of the Stomach, Adenocarcinoma of Esophagogastric Junction, Epstein-Barr Virus-Associated Gastric Carcinoma
07/26
07/29
NCT05688488: Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords

Recruiting
1/2
100
RoW
Curcumin, Mitomycin-C
Eye & ENT Hospital of Fudan University
Glottic Web of Larynx, Laryngeal Stenosis, Glottic Carcinoma, Laryngeal Leucoplakia, Laryngeal Polyp, Laryngeal Papilloma
12/25
12/26
GQ1005-102, NCT06154343: A Study of GQ1005 in Subjects With HER2-Expressing Advanced Solid Tumors

Recruiting
1
150
RoW
GQ1005
GeneQuantum Healthcare (Suzhou) Co., Ltd.
HER2 Expressing or Mutated Advanced Malignant Solid Tumors
12/24
07/25
NCT06614686: U87 CAR-T in Patients With Advanced Head and Neck Tumors

Recruiting
1
20
RoW
U87 autologous CAR T-cell
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd
Nasopharynx Cancer, Head and Neck Cancer
10/26
12/27
NCT05685719: A Study to Evaluate the Relative Bioavailability of STI-1558 and the Effect of Itraconazole and Rifampin on the Pharmacokinetics of STI-1558

Completed
1
37
RoW
STI-1558, Itraconazole, Rifampin
Zhejiang ACEA Pharmaceutical Co. Ltd.
COVID-19 Pneumonia
03/23
11/23
NCT05627063: A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK121-NX in Patients With Advanced Solid Tumors

Recruiting
1
169
US, RoW
ABSK121-NX
Abbisko Therapeutics Co, Ltd
Solid Tumor
03/25
06/25
HF1K16-101, NCT05388487: Tolerability and Safety of HF1K16 Injection in Patients With Refractory Solid Tumors

Recruiting
1
54
RoW
HF1K16 /Arm 45 mg/m², HF1K16 /Arm 90 mg/m², HF1K16 /Arm 120 mg/m², HF1K16 /Arm 160 mg/m², HF1K16 /Arm 120 mg or 180 mg
HighField Biopharmaceuticals Corporation, Tigermed Consulting Co., Ltd
Solid Tumor, Adult
04/25
11/25
NCT05861895: A Clinical Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HF158K1 in Participants With HER-2 Positive or HER-2 Low Expression Advanced Solid Tumors

Recruiting
1
84
US
HF158K1 /Arm 2 mg/m², Infusion, HF158K1 /Arm 6 mg/m², HF158K1 /Arm 15 mg/m², HF158K1 /Arm 30 mg/m², HF158K1 /Arm 45 mg/m², HF158K1 /Arm 60 mg/m²
HighField Biopharmaceuticals Corporation
Solid Tumors, Adult
04/25
12/25
NCT05827328: Explore the Optimal Surgical Timing for Lung Surgery and Mediastinal Surgery After COVID-19 Infection

Completed
N/A
2000
RoW
Observation
Shanghai Pulmonary Hospital, Shanghai, China
Thoracic Diseases, Thoracic Surgery
06/23
06/23
NCT06340295: A Multicenter, Prospective Cohort Study of Preserved Ratio Impaired Spirometry(PRISm) in a Population

Recruiting
N/A
2000
RoW
Peking University First Hospital, Shanxi Bethune Hospital, First Affiliated Hospital Xi'an Jiaotong University, Tianjin Medical University General Hospital, The First Hospital of Qinhuangdao, Shandong Provincial Hospital, Second Hospital of Jilin University, People's Hospital of Xinjiang Uygur Autonomous Region, MinDong Hospital of Ningde City
COPD
05/26
05/26
EWVCWDC, NCT05974670: Early Warning Value of Consumer Wearable Devices in AECOPD

Recruiting
N/A
150
RoW
Consumer wearable device
Peking University First Hospital
COPD
09/23
09/23
CHENJIAN1, NCT06126393: MRI Radiomics Combined With Pathomics on the Prediction of Molecular Classification and Prognosis of Endometrial Cancer

Not yet recruiting
N/A
350
RoW
next generation sequencing AND Immunohistochemical examination, Magnetic resonance examination
Fujian Cancer Hospital, Fujian Provincial Hospital, First Affiliated Hospital of Fujian Medical University, Gutian Hospital
Endometrial Neoplasms
03/27
06/27
NCT06396143: Research on Intelligent Screening and Decision-making for Neoadjuvant Therapy in Locally Advanced Gastric Cancer Based on Multi-omics Integration

Recruiting
N/A
120
RoW
Zhejiang University
Locally Advanced Gastric Carcinoma
06/25
12/25
NCT06551675: Effect of Silkworm Pupa Tablets in Gastrointestinal Malignancies at Nutritional Risk Following Radical Surgery

Recruiting
N/A
120
RoW
Silkworm pupa tablets, Control product
Xiaosun Liu, MD
Nutritional Deficiency, Gastrointestinal Cancer, Frailty Syndrome
11/25
11/25
NCT06140589: Exploring the Efficacy, Safety and Cost-effectiveness Analysis of Cadonilimab in the Treatment of Cervical Cancer

Recruiting
N/A
200
RoW
Cadonilimab
Fujian Cancer Hospital, Fujian Medical University Affiliated Nanping First Hospital, The First Hospital Affiliated to Fujian Medical University, Fujian Medical University Union Hospital, Gutian Hospital, Jiangxi Provincial Cancer Hospital, Shunde Women and Children's Hospital (Maternity and Child Healthcare Hospital of Shunde Foshan), Lianyungang Donghai County People's Hospital, Changsha Maternal and Child Health Hospital, Pingxiang Maternal and Child Health Hospital, Huinan County People's Hospital, People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Cervical Cancer
12/24
12/26
NCT04212494: Thrombus Aspiration in STEMI Patients With High Thrombus Burden

Recruiting
N/A
3838
RoW
Thrombus aspiration, PCI Alone
Guangdong Provincial People's Hospital, Zhongshan People's Hospital, Guangdong, China, Kaiping Central Hospital, The Second Affiliated Hospital of Shantou University Medical College, The Third Xiangya Hospital of Central South University, Sihui City People's Hospital, Shenzhen Baoan District Shiyan People's Hospital, People's Hospital of Nanxiong County, Yuebei People's Hospital, Weifang Medical University, Wuzhou Gongren Hospital, Dafeng Hospital of Chaoyang District in Shantou City, Shenzhen Baoan People's Hospital, Dongguan People's Hospital, Yangchun People's Hospital, Taishan People's Hospital, The Second People's Hospital of Foshan, Guangzhou Hospital of integrated Traditional and West Medicine, Guangning People's Hospital, Foshan Sanshui District People's Hospital, Qingyuan People's Hospital, Luhe County People's Hospital, People's Hospital of Xinjiang Uygur Autonomous Region, The Fourth People's Hospital of Chenzhou, People's Hospital of Dapu County, Shenzhen People's Hospital, Heyuan people's Hospital, Huaiji People's Hospital, People's Hospital of Yingde City, Qingyuan Hospital of Traditional Chinese Medicine Affiliated To Guangzhou University of Traditional Chinese Medicine, Zhongshan Hospital Of Traditional Chinese Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Lianzhou People's Hospital, Lianping Xian Ren Ming Yi Yuan, Guangxi Zhuang Autonomous Region Nationalities Hospital, Liuzhou Municipal Liutie Central Hospital, Chen Zhou 3RD People's Hospital, Longgang District Central Hospital of Shenzhen, The Affiliated Shunde Hospital of Jinan University, Shenzhen Longhua District Central Hospital, Shantou Central Hospital, Tongxiang First People's Hospital, Bobai County People's Hospital, Guangxi, Meizhou Traditional Chinese Medicine Hospital, The Third Affiliated Hospital of Sun Yat-Sen University, Yuedong Hospital, Shenzhen Third People's Hospital, Yangjiang People's Hospital, Jiangmen Central Hospital, Eighth Affiliated Hospital, Sun Yat-sen University, The First People's Hospital of Kashgar Erea, First People's Hospital of Foshan, Zhaoqing Gaoyao People's Hospital, People's Hospital of Nanhai District, Foshan, The Second Affiliated Hospital of Dalian Medical University, Nanning Second People's Hospital, The Second People's Hospital of Nanhai District of Foshan, Shangyou People's Hospital
ST-segment Elevation Myocardial Infarction (STEMI)
08/25
02/26
NCT04912401: the Efficacy and Safety of Etanercept (Yi Sai Pu) in Chinese Patients With Moderate-to-Severe Psoriasis

Recruiting
N/A
100
RoW
Second Affiliated Hospital, School of Medicine, Zhejiang University
Psoriasis, Etanercept
12/25
12/25
NCT04995159: Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVasâ„¢ BRS System

Not yet recruiting
N/A
2150
RoW
Single anti-platelet therapy, SAPT strategy, Dual anti-platelet therapy, DAPT strategy
Lepu Medical Technology (Beijing) Co., Ltd.
Coronary Heart Disease
01/26
01/28
REPAIR PERS-AF, NCT06098989: A Prospective Study of REPeat Ablation In Patients With Recurrent PERSistent Atrial Fibrillation: Pulmonary Vein Isolation vs. Adjunct Posterior Wall Isolation ( Study)

Not yet recruiting
N/A
150
NA
Radio frequency ablation
Haukeland University Hospital, St. Olavs Hospital, University Hospital of North Norway
Atrial Fibrillation, Persistent, Atrial Fibrillation Recurrent
11/26
11/26
NCT05540821: Efficacy of Double Contrast-enhanced Ultrasound of Pelvic in Preoperative Evaluation of Deep Endometriosis

Recruiting
N/A
156
RoW
Hysterosalpingo-contrast sonography and sonoPODography
Shenzhen Second People's Hospital
Deep Endometriosis
06/25
06/25
NCT05697926: Preclinical Research for Personalized TCR-T Therapy for Head and Neck Cancer

Recruiting
N/A
100
RoW
No intervention
Eye & ENT Hospital of Fudan University
Head and Neck Cancer
12/25
06/26
Fu, Jun zhou
NCT04543461: American Lung Association (ALA) Lung Health Cohort

Recruiting
N/A
4000
US
Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI), American Lung Association, Stanford University
Lung Diseases
09/26
09/26
MATCH, NCT03978936: Medication Adherence With Telehealthcare Medication Therapy Management

Active, not recruiting
N/A
300
US
Medication Therapy Management (MTM) Video Telehealthcare, Electronic Adherence Self-Management (EAM)
Johns Hopkins University, Nemours Children's Health System, American Lung Association, National Heart, Lung, and Blood Institute (NHLBI)
Uncontrolled Asthma, Young Adults
01/25
06/25
Liu, Zheng rong
NCT05080322: Efficacy and Safety of On-demand and Continuous Administration of Nasal Spray in the Treatment of Allergic Rhinitis

Recruiting
4
150
RoW
Fluticasone Nasal 50 Mcg/Inh Nasal Spray, Azelastine Nasal 140 Mcg/Inh Nasal Spray, Flixonase,H20140117, AZEP,H20150201, Fluticasone Nasal 50 Mcg/Inh Nasal Spray, Flixonase,H20140117
Zheng Liu ENT, Wuhan Union Hospital, China, Zhongnan Hospital, The People's Hospital of Hebei Province
Allergic Rhinitis
12/24
01/25
SAST, NCT04088513: Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency

Recruiting
4
440
RoW
Aspirin, Acetylsalicylic acid, Clopidogrel, Plavix
First Affiliated Hospital, Sun Yat-Sen University
G6PD Deficiency, Stroke
12/24
12/24
NCT03431428: Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients

Recruiting
3
477
RoW
transanal surgery, Miles surgery, Preoperative chemoradiotherapy
Zhang Rui
Almost-cCR, Surgery, Rectal Cancer
01/20
12/22
NCT06200766: A Multicenter, Randomized, Double-blind, Three-arm, Parallel Clinical Endpoint Bioequivalence Study of Monometasone Furoate Nasal Spray in Patients With Seasonal Allergic Rhinitis

Recruiting
3
640
RoW
Mometasone furoate as a nasal spray
Zheng Liu ENT, Zhejiang Xianju Pharma Tech. Co., Ltd
Seasonal Allergic Rhinitis
04/24
06/24
NCT06364904: An Phase III Study, Multicenter,Randomized Controlled Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma.

Not yet recruiting
3
210
RoW
Tislelizumab, Cisplatin, Gemcitabine and Trilaciclib, Tislelizumab, Cisplatin, Gemcitabine
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Bladder Cancer
04/27
04/29
NCT05844150: A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC

Recruiting
2/3
445
RoW
PM8002, Platinum, Atezolizumab, Etoposide
Biotheus Inc.
SCLC
06/25
12/25
NCT06315426: A Study of IL4Rα Monoclonal Antibody in Patients With Seasonal Allergic Rhinitis(SAR).

Not yet recruiting
2
90
NA
GR1802 injection, Placebo
Genrix (Shanghai) Biopharmaceutical Co., Ltd.
Allergic Rhinitis
10/24
12/24
BGB-3111-2005-IIT, NCT05356858: An Open Label Study of the Effects and Safety of Zanubrutinib in NMOSDs Adult Patients

Recruiting
2
20
RoW
zanubrutinib
Xuanwu Hospital, Beijing
Neuromyelitis Optica
10/24
10/24
NCT06760182: Clinical Trial of TQH2722 Injection in Patients With Seasonal Allergic Rhinitis

Not yet recruiting
2
168
RoW
TQH2722 injection, TQH2722 Placebo
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.
Seasonal Allergic Rhinitis
06/25
08/25
NCT06364956: Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma

Recruiting
1/2
36
RoW
Tislelizumab combined with two predefined dose groups of palbociclib, RP2D dose Of Tislelizumab combined with palbociclib was selected for phase II clinical trial.
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Bladder Cancer
06/25
06/26
NCT05009134: Influences of Allergic Rhinitis and Allergen Immunotherapy on SARS-CoV-2 Vaccination

Recruiting
N/A
120
RoW
There is no intervention in this study.
Huazhong University of Science and Technology, National Natural Science Foundation of China
Allergic Rhinitis, Allergen Immunotherapy, SARS-CoV-2
03/22
04/22
NCT05983003: Research on Identifying and Treatment Prognosis of Chronic Rhinosinusitis Based on Image and Sequencing Data

Completed
N/A
3500
RoW
endoscopic sinus surgery, ESS
Zheng Liu
Chronic Sinusitis, Radiology, Pathology, Surgery, Progression
04/24
04/24
EMRESSECRS, NCT04852562: The Effect of Modified Radical Endoscopic Sinus Surgery on Eosinopilic Chronic Rhinosinusitus With Nasal Polyps

Recruiting
N/A
110
RoW
Modified radical endoscopic sinus surgery, MRESS, functional endoscopic sinus surgery, FESS
Zheng Liu
Chronic Sinusitis, Endoscopic Sinus Surgery, Nasal Polyps
12/23
12/24
NCT06198894: Steroid-eluting Sinus Stent for Chronic Rhinosinusitis Patients With Uncontrolled Postoperative Symptoms

Recruiting
N/A
96
RoW
steroid-eluting sinus stent implant, BISORB bioabsorbable steroid-eluting sinus stent, Systemic glucocorticoids, Medrol, saline irrigations, 0.9% sodium chloride solution, Placebo, Systemic glucocorticoid placebo, sham procedure, In-office bilateral sham procedure of stent placement
Zheng Liu
Chronic Sinusitis
01/26
04/26
NCT06240104: Monitoring of Heart to Guide Myocardial Injury Patients to Wean From Ventilation

Recruiting
N/A
200
RoW
cardiac output index monitor
Peking University People's Hospital
Myocardial Ischaemia During Surgery
12/25
12/25
NCT06370468: The Epidemiological and Intrinsic Characteristics of Chronic Rhinitis

Recruiting
N/A
150000
RoW
Epidemiological investigation
Zheng Liu ENT, Peking Union Medical College, Hainan People's Hospital, Shandong Second Provincial General Hospital, First Affiliated Hospital of Chongqing Medical University, First Affiliated Hospital of Xinjiang Medical University
Chronic Rhinitis
05/27
08/27
NCT06474923: Multimodal Data-assisted Primary Screening for Allergic Rhinitis Based on Voice Recognition and Face Recognition

Recruiting
N/A
1500
RoW
Face image and voice audio
Zheng Liu
Body Image, Speech Sound Disorder
12/24
06/25
NCT06462417: Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis

Not yet recruiting
N/A
15
RoW
Arbidol, Arbidol Hydrochloride
Zheng Liu, National Natural Science Foundation of China
Allergic Rhinitis
06/25
06/25
CATHEDRAL, NCT05134129: Correlation Between Targeted HbA1c Values and Prevention of Recurrent Cardiovascular Events in Type 2 Diabetes After PCI

Recruiting
N/A
1500
RoW
Shanghai 10th People's Hospital
Diabetes Mellitus, Percutaneous Coronary Intervention
09/24
09/24
NCT05444491: Application of Polygenic Methylation Markers in Postoperative Recurrence Monitoring of Colorectal Cancer

Recruiting
N/A
1200
RoW
Singlera Genomics Inc., Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Colorectal Cancer
06/25
06/25
Yu, Xueqing
AURORA, NCT03214731: Efficacy and Safety of Artesunate Plus Standard of Care in Active Lupus Nephritis

Recruiting
4
90
RoW
Artesunate, Art, placebo
Sun Yat-sen University, The First People's Hospital of Yunnan, The First Affiliated Hospital of Nanchang University, General Hospital of Ningxia Medical University, First Affiliated Hospital of Fujian Medical University, Shenzhen Second People's Hospital, The Third Xiangya Hospital of Central South University, Tongji Hospital
Lupus Nephritis
09/22
09/22
LUMINA, NCT03200210: Lowering-hyperuricemia Treatment on Cardiovascular Outcomes in Peritoneal Dialysis Patients

Recruiting
4
548
RoW
Febuxostat, Febuxostat Tablets, Placebo
Sun Yat-sen University
Hyperuricemia
12/22
12/22
NCT04381143: ASPIrin in Reducing Events in Dialysis ( ASPIRED )

Recruiting
4
9000
RoW
Aspirin 100 mg Oral Tablet, Matching Placebo
Guangdong Provincial People's Hospital, The George Institute
CKD (Chronic Kidney Disease) Stage 5D
09/26
12/26
NCT06016036: SAL-0951 Tablets in the Treatment of Renal Anemia in Non-dialysis Chronic Kidney Disease

Completed
3
156
RoW
SAL-0951, SAL-0951 group, Placebo, Placebo phase
Shenzhen Salubris Pharmaceuticals Co., Ltd.
Renal Anemia in Non-dialysis Chronic Kidney Disease
10/21
02/22
SHR6508-301, NCT06434961: The Trial of SHR6508 in Secondary Hyperparathyroidism

Recruiting
3
486
RoW
SHR6508 plus oral placebo tablets, Cinacalcet plus intravenous placebo
Shanghai Hengrui Pharmaceutical Co., Ltd.
Secondary Hyperparathyroidism
06/25
07/25
NCT05663411: A Study of SHR6508 in Secondary Hyperparathyroidism

Active, not recruiting
2
75
RoW
SHR6508, Cinacalcet
Shanghai Hengrui Pharmaceutical Co., Ltd.
Secondary Hyperparathyroidism
10/23
11/23
 

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