| Wassen, Martine |
| Recruiting | N/A | 372 | Europe | PICO glasses and controller with BirthVR | Zuyderland Medisch Centrum, Diakonessenhuis, Utrecht | Virtual Reality, Labor Pain, Labor Analgesia | 07/23 | 09/23 | | |
| Recruiting | N/A | 124 | Europe | Vaginal NOTES hysterectomy, Vaginal hysterectomy | Zuyderland Medisch Centrum, Catharina Ziekenhuis Eindhoven | Hysterectomy, Natural Orifice Transluminal Endoscopic Surgery, Vaginal Hysterectomy | 12/24 | 07/25 | | |
| Recruiting | N/A | 103 | Europe | Metformin | Zuyderland Medisch Centrum | Gestational Diabetes, Gestational Diabetes Mellitus | 12/25 | 12/25 | | |
| Piessen, Guillaume |
SURGIGAST, NCT03042169: Surgical Resection Plus Chemotherapy Versus Chemotherapy Alone in Oligometastatic Stage IV Gastric Cancer |
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| Recruiting | 3 | 424 | Europe | Preoperative Chemotherapy, Surgery, surgical removal of the primary tumour followed by chemotherapy, Postoperative chemotherapy | University Hospital, Lille, National Cancer Institute, France | Gastric Adenocarcinoma | 02/23 | 02/23 | | |
FLUOCOL-1, NCT05168839: Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage |
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| Recruiting | 3 | 1010 | Europe | FLUO+ : Intraoperative fluorescence angiography (IOFA) with indocyanine green (ICG). | Centre Hospitalier Universitaire de Besancon | Colorectal Cancer | 10/25 | 10/25 | | |
| Recruiting | 2/3 | 1075 | Europe | Induction chemotherapy - modified FOLFIRINOX regimen, Early tumor response evaluation by MRI volumetry, Radiochemotherapy Cap 50, Radical proctectomy with total mesorectal excision | Institut du Cancer de Montpellier - Val d'Aurelle | Locally Advanced Malignant Neoplasm, Rectal Carcinoma | 08/27 | 08/27 | | |
PROTECT, NCT02359968: PReoperative Chemoradiation (Paclitaxel-carboplatin or FOLFOX) for Resectable Esophageal and Junctional Cancer |
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| Completed | 2 | 106 | Europe | FOLFOX, Fluorouracil, Oxaliplatin, Folinic acid, Elvorine, CarboP-pacliT, Carboplatine, paclitaxel | Centre Oscar Lambret, National Cancer Institute, France | Esophageal Neoplasms, Gastro-esophageal Junction Cancer | 01/21 | 02/24 | | |
NEONIPIGA, NCT04006262: Pre-operative Nivolumab and Ipilimumab, Followed by Post-operative Nivolumab, for MSI/dMMR Oeso-gastric Adenocarcinoma. |
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| Recruiting | 2 | 32 | Europe | Nivolumab 10 MG/ML, Opdivo, Ipilimumab 200 MG in 40 ML Injection, Yervoy | GERCOR - Multidisciplinary Oncology Cooperative Group, Bristol-Myers Squibb | Localized Oesogastric Adenocarcimona, MSI and or dMMR | 06/24 | 06/24 | | |
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DEWI, NCT06059495: Watch-and-Wait Approach With Dostarlimab in Localized dMMR/MSI-H Gastric Cancer: GERCOR Phase II Study |
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| Recruiting | 2 | 59 | Europe | Dostarlimab, Jemperli | GERCOR - Multidisciplinary Oncology Cooperative Group | Adenocarcinoma - GEJ, Gastric Adenocarcinoma | 09/28 | 09/28 | | |
| Recruiting | N/A | 402 | Europe | treatment for ampullary adenocarcinoma, no other intervention name to add | Federation Francophone de Cancerologie Digestive | Ampullary Adenocarcinoma | 12/22 | 12/22 | | |
LARS, NCT03569488: Validation of the French Version of the Low Anterior Resection Syndrome () Among Rectal Cancer Patients |
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| Recruiting | N/A | 1100 | Europe | FT-LARS questionnaire | University Hospital, Caen, National Cancer Institute, France, French Research Group of Rectal Cancer Surgery (GRECCAR), Institut National de la Santé Et de la Recherche Médicale, France | Rectal Cancer Patients | 09/23 | 12/24 | | |
| Recruiting | N/A | 1500 | Europe | collection of biological samples | University Hospital, Toulouse | Adenocarcinoma, Carcinoma, Neoplasms | 01/35 | 02/35 | | |
GRECCAR-9, NCT02841293: Cost-utility of Two Strategies of Perineal Reconstruction After Abdominoperineal Resection for Anorectal Carcinoma |
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| Recruiting | N/A | 140 | Europe | Biological mesh, Primary perineal wound closure | University Hospital, Toulouse | Abdominoperineal Resection | 02/24 | 02/24 | | |
Endeavor-1, NCT06523374: A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer |
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| Not yet recruiting | N/A | 50 | Europe | Endoscopic brush cytology | University Hospital, Antwerp, Karolinska Institutet, Universal Diagnostics, Amsterdam UMC, Radboud University Medical Center, AZ Delta, Centre Hospitalier Universitaire de Liege, University of Leipzig, IRCCS Ospedale San Raffaele, Karolinska University Hospital, University of Dublin, Trinity College, Heinrich-Heine University, Duesseldorf, GZA Ziekenhuizen Campus Sint-Augustinus, University Hospital, Ghent, Rigshospitalet, Denmark, Universitätsklinikum Leipzig, St. James's Hospital, Ireland | Barrett's Esophagus, Esophageal Adenocarcinoma | 11/25 | 11/26 | | |
| Active, not recruiting | N/A | 258 | Europe | Questionnaire | University Hospital, Lille, University of Lille Nord de France | Oesophageal Carcinoma, Gastric Adenocarcinoma | 05/25 | 05/25 | | |
HIATUS, NCT05867225: Onlay Synthetic Bioabsorbable Mesh Herniorrhaphy Versus Herniorrhaphy Only in the Primary Treatment of Large Hiatal Hernia |
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| Recruiting | N/A | 256 | Europe | Laparoscopic hiatal hernia repair | University Hospital, Bordeaux | Large Hiatal Hernia | 01/28 | 01/28 | | |
GRECCAR17, NCT05233787: Trial Evaluating the Tailored Versus the Systematic Use of Defunctioning Stoma After Total Mesorectal Excision for Rectal Cancer |
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| Recruiting | N/A | 212 | Europe | Tailored use of defunctioning stoma after TME, Systematic use of defunctioning stoma | University Hospital, Bordeaux | Rectal Cancer, Ileostomy; Functional Disturbance | 09/25 | 09/25 | | |
| Recruiting | N/A | 15000 | Europe | | University Hospital, Lille, French Eso-Gastric Tumors Working Group, National Cancer Institute, France | Esophageal Disease | 05/27 | 05/27 | | |
| Recruiting | N/A | 10000 | Europe, US | Esophagectomy for esophageal cancer | Universitaire Ziekenhuizen KU Leuven | Esophageal Neoplasms, Esophagectomy, Brain Metastases | 03/25 | 03/25 | | |
| Not yet recruiting | N/A | 30 | NA | Digital platform | University Hospital, Lille, Santelys Association, ENGIE, Fondation Boulanger | Esophageal Neoplasm, Laryngeal Neoplasms | 09/23 | 09/23 | | |
| Sosef, Meindert |
| Recruiting | N/A | 2000 | Europe | retrospective | University Medical Center Groningen, Dutch Cancer Society, Comprehensive Cancer Centre The Netherlands, Dutch Institute for Clinical Auditing (DICA), ZorgTTP | The Aim of This Project is to Develop and Validate NTCP-models for Complications After nCRT (and Surgical Resection) | 06/25 | 06/30 | | |
| Recruiting | N/A | 10000 | Europe, US | Esophagectomy for esophageal cancer | Universitaire Ziekenhuizen KU Leuven | Esophageal Neoplasms, Esophagectomy, Brain Metastases | 03/25 | 03/25 | | |
| Hof, Arnoud WJ van 't |
| Recruiting | 3 | 2499 | Europe, Canada, RoW | zalunfiban, RUC-4, Placebo | CeleCor Therapeutics | ST-elevation Myocardial Infarction (STEMI) | 12/24 | 12/24 | | |
| Recruiting | N/A | 99999 | Europe | | Radboud University Medical Center, Maastricht Universitair Medisch Centrum, Zuyderland Medisch Centrum, VieCuri Medical Centre | Coronary Artery Disease, Acute Coronary Syndrome, Chronic Coronary Syndrome | 01/50 | 01/50 | | |
NCT06171893: Assessing the Effect of the 'Wavy' Application, on Stress and Burden of Disease in Women With INOCA |
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| Completed | N/A | 117 | Europe | Wavy stress application | Radboud University Medical Center, VieCuri Medical Centre, The Elisabeth-TweeSteden Hospital, Maastricht University Medical Center, Maasstad Hospital, Catharina Ziekenhuis Eindhoven, ZonMw: The Netherlands Organisation for Health Research and Development, Health Holland, Netherlands Organisation for Scientific Research | Stress, Ischemia, Vasospasm, Coronary, Vasomotor; Spasm, Angina, Stable, Prinzmetal Angina | 12/22 | 12/22 | | |
| Recruiting | N/A | 852 | Europe | modified HEART score (including POC hs cTnI analysis), Standard care and triage according to the local (EMT)protocol. | VieCuri Medical Centre, Siemens Healthineers Nederland B.V. | Chest Pain, Acute Coronary Syndrome, Myocardial Infarction, Myocardial Ischemia, Heart Attack | 06/23 | 06/24 | | |
SLIM, NCT03562572: FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease |
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| Recruiting | N/A | 476 | Europe, RoW | Ischemia driven revascularization, Usual care group | Zuyderland Medisch Centrum, Maastricht University Medical Center, Radboud University Medical Center, Jeroen Bosch Ziekenhuis, VieCuri Medical Centre, Gottsegen György Országos Kardiológiai Intézet, Bács-Kiskun County Teaching Hospital, Brno University Hospital, Szeged University | Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI, Fractional Flow Reserve, Myocardial, Myocardial Revascularization, Percutaneous Coronary Intervention | 12/25 | 01/28 | | |
REHAB+, NCT05207072: Mobile Tele-Monitoring Guided Cardiac Rehabilitation in Post-Acute Coronary Syndrome Patients |
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| Recruiting | N/A | 900 | Europe | | Maastricht University | Cardiac Rehabilitation, Acute Coronary Syndrome | 09/23 | 12/23 | | |
| Rasoul, Saman |
NCT06383390: The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES) |
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| Recruiting | 3 | 10000 | Europe, Canada, US, RoW | Retatrutide, LY3437943, Placebo | Eli Lilly and Company | Overweight and Obesity | 02/29 | 02/29 | | |
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN |
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| Recruiting | N/A | 1400 | Europe, US, RoW | Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation | Medtronic Vascular | Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus | 11/26 | 11/29 | | |
SLIM, NCT03562572: FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease |
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| Recruiting | N/A | 476 | Europe, RoW | Ischemia driven revascularization, Usual care group | Zuyderland Medisch Centrum, Maastricht University Medical Center, Radboud University Medical Center, Jeroen Bosch Ziekenhuis, VieCuri Medical Centre, Gottsegen György Országos Kardiológiai Intézet, Bács-Kiskun County Teaching Hospital, Brno University Hospital, Szeged University | Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI, Fractional Flow Reserve, Myocardial, Myocardial Revascularization, Percutaneous Coronary Intervention | 12/25 | 01/28 | | |
| Rasoul, S |
| Recruiting | 3 | 2499 | Europe, Canada, RoW | zalunfiban, RUC-4, Placebo | CeleCor Therapeutics | ST-elevation Myocardial Infarction (STEMI) | 12/24 | 12/24 | | |
SLIM, NCT03562572: FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease |
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| Recruiting | N/A | 476 | Europe, RoW | Ischemia driven revascularization, Usual care group | Zuyderland Medisch Centrum, Maastricht University Medical Center, Radboud University Medical Center, Jeroen Bosch Ziekenhuis, VieCuri Medical Centre, Gottsegen György Országos Kardiológiai Intézet, Bács-Kiskun County Teaching Hospital, Brno University Hospital, Szeged University | Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI, Fractional Flow Reserve, Myocardial, Myocardial Revascularization, Percutaneous Coronary Intervention | 12/25 | 01/28 | | |
| Vainer, J |
| Recruiting | 3 | 2499 | Europe, Canada, RoW | zalunfiban, RUC-4, Placebo | CeleCor Therapeutics | ST-elevation Myocardial Infarction (STEMI) | 12/24 | 12/24 | | |
SLIM, NCT03562572: FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease |
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| Recruiting | N/A | 476 | Europe, RoW | Ischemia driven revascularization, Usual care group | Zuyderland Medisch Centrum, Maastricht University Medical Center, Radboud University Medical Center, Jeroen Bosch Ziekenhuis, VieCuri Medical Centre, Gottsegen György Országos Kardiológiai Intézet, Bács-Kiskun County Teaching Hospital, Brno University Hospital, Szeged University | Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI, Fractional Flow Reserve, Myocardial, Myocardial Revascularization, Percutaneous Coronary Intervention | 12/25 | 01/28 | | |
| Smeets, Anouk |
| Completed | N/A | 4855 | Europe | Consultation at spine-centre | Zuyderland Medisch Centrum | Spine Disease, Characteristics Disease, Spinal Disease, Demography | 03/23 | 05/23 | | |
| Recruiting | N/A | 198 | Europe | ACDF, Anterior Cervical Discectomy and Fusion, ACDA, Anterior Cervical Discectomy and arthroplasty | Valérie Schuermans | Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region, Radiculopathy; in Spondylosis, Radiculopathy; in Intervertebral Disc Disorder, Myelopathy Neurological, Myelopathy Due to Spondylosis, Cervical Disc Disease, Cervical Disc Herniation, Cervical Disc Degeneration, Cervical Disc Disorder With Myelopathy, Cervical Disc Prolapse With Myelopathy, Cervical Spondylosis, Cervical Fusion, Cervical Disc Disorder With Radiculopathy, Cervical Disc Prolapse With Radiculopathy, Fusion of Spine, Disc Prolapse Cervical | 06/26 | 06/28 | | |
| Bosch, Julie Van Den |
| Recruiting | N/A | 10000 | Europe, US | Esophagectomy for esophageal cancer | Universitaire Ziekenhuizen KU Leuven | Esophageal Neoplasms, Esophagectomy, Brain Metastases | 03/25 | 03/25 | | |
| Luijkx, Jasper |
RE-DUAL PCI, NCT04688723: Dual Therapy With Dabigatran/Ticagrelor Versus Dual Therapy With Dabigatran/Clopidogrel in ACS Patients With Indication for NOAC Undergoing PCI |
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| Recruiting | 4 | 1000 | Europe | Dabigatran + Ticagrelor, Dabigatran + clopidogrel | Zuyderland Medisch Centrum, Boehringer Ingelheim | Coronary Artery Disease, Myocardial Ischemia, Myocardial Infarction, Atrial Fibrillation | 12/22 | 07/23 | | |
| Winkler, Patty |
RE-DUAL PCI, NCT04688723: Dual Therapy With Dabigatran/Ticagrelor Versus Dual Therapy With Dabigatran/Clopidogrel in ACS Patients With Indication for NOAC Undergoing PCI |
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| Recruiting | 4 | 1000 | Europe | Dabigatran + Ticagrelor, Dabigatran + clopidogrel | Zuyderland Medisch Centrum, Boehringer Ingelheim | Coronary Artery Disease, Myocardial Ischemia, Myocardial Infarction, Atrial Fibrillation | 12/22 | 07/23 | | |
| Boerma, Evert-Jan |
| Active, not recruiting | 4 | 302 | Europe | Augmentin + Gentamicin, Amoxicillin/clavulanic acid (Augmentin) + Gentamicin, Appendectomy | Ramon Gorter, ZonMw: The Netherlands Organisation for Health Research and Development, Amsterdam UMC, location VUmc | Appendicitis | 12/24 | 12/24 | | |
CAPP, NCT04755179: Identification of the Optimal Treatment Strategy for Complex Appendicitis in the Pediatric Population |
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| Completed | N/A | 1308 | Europe | Laparoscopic appendectomy, Open appendectomy, Non-operative treatment, Direct appendectomy | Ramon Gorter, ZonMw: The Netherlands Organisation for Health Research and Development, Amsterdam UMC, location VUmc | Appendicitis, Appendix Mass, Appendicitis Perforated | 07/24 | 07/24 | | |
| Curfs, Inez |
| Completed | N/A | 30 | Europe | Motion analysis | Zuyderland Medisch Centrum, Zuyd University of Applied Sciences | Sacroiliac Joint Dysfunction | 09/22 | 12/22 | | |
| Hermans, Sem |
| Completed | N/A | 30 | Europe | Motion analysis | Zuyderland Medisch Centrum, Zuyd University of Applied Sciences | Sacroiliac Joint Dysfunction | 09/22 | 12/22 | | |
| Musters, Anne-Claire |
| Recruiting | N/A | 372 | Europe | PICO glasses and controller with BirthVR | Zuyderland Medisch Centrum, Diakonessenhuis, Utrecht | Virtual Reality, Labor Pain, Labor Analgesia | 07/23 | 09/23 | | |
| Wijk, Sandra van |
| Active, not recruiting | N/A | 506 | Europe | Lifestyle advice for liberal fluid intake | Radboud University Medical Center, Maastricht University Medical Center | Heart Failure | 09/24 | 12/24 | | |
| Recruiting | N/A | 466 | Europe | Urine sodium guided diuretic algorithm, Usual care | Zuyderland Medisch Centrum | Heart Failure Acute | 06/25 | 02/26 | | |
| Kinet, Sam |
NCT05396703: TOETVA Feasibility and Complications - Single Center First Experience |
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| Completed | N/A | 18 | Europe | TOETVA | Zuyderland Medisch Centrum | Thyroid Gland Disease, Surgery | 05/22 | 06/23 | | |
| Completed | N/A | 60 | Europe | Endoscopic eTEP, Open Rives-Stoppa | AZ Alma | Hernia, Ventral, Rectus Diastasis | 08/22 | 12/22 | | |
| Hoef, T P van de |
| Recruiting | 3 | 2499 | Europe, Canada, RoW | zalunfiban, RUC-4, Placebo | CeleCor Therapeutics | ST-elevation Myocardial Infarction (STEMI) | 12/24 | 12/24 | | |
| Belgers, Eric |
A1Check, NCT05810207: the External Validation of a Machine Learning Model Predicting Colorectal Anastomotic Leakage |
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| Recruiting | N/A | 1000 | Europe | Colorectal resection | Freek Daams, SAS Institute | Anastomotic Leak, Anastomotic Leak Large Intestine, Anastomotic Complication, Anastomotic Leak Rectum | 07/24 | 12/24 | | |
| Claassen, Lieke |
| Recruiting | N/A | 700 | Europe | No intervention, observational. | Zuyderland Medisch Centrum | Emergency Care, Acute Care Chain | 12/24 | 12/24 | | |
