| Klei, Wilton A van |
| Terminated | N/A | 342 | Europe, Canada | Perioperative withdrawal of angiotensin converting enzyme inhibitors and angiotenin receptor blockers, Blood draw, Diary to register drug adherence, Quality of life questionnaire, WHODAS questionnaire | UMC Utrecht, ZonMw: The Netherlands Organisation for Health Research and Development | Surgery, Angiotensin Hypertension, Perioperative Complication | 02/23 | 09/23 | | |
| Recruiting | N/A | 50 | Canada | Healthy lifestyle behaviors around the time of surgery | University Health Network, Toronto | Cardiovascular Diseases, Risk Reduction Behavior | 04/25 | 10/25 | | |
| Not yet recruiting | N/A | 50 | Canada | Treatment bundle of care, Control Group | University Health Network, Toronto | Kidney Transplant, Kidney Failure, Kidney Injury | 01/26 | 04/26 | | |
| Feld, Jordan |
NCT04017338: Transplantation Using Hepatitis C Positive Donors, A Safety Trial |
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| Recruiting | 3 | 40 | Canada | Glecaprevir 300 MG / Pibrentasvir 120 MG Oral Tablet, Maviret, Ezetimibe 10Mg Oral Tablet, Ex Vivo Lung Perfusion, Normothermic EVLP | Jordan Feld, University Health Network, Toronto | Lung Transplant Infection, Heart Transplant Infection, Kidney Transplant Infection, Kidney Pancreas Infection, Hepatitis C | 12/20 | 12/24 | | |
NCT04967430: TOGETHER - Toronto: Trial to Evaluate the Effect of Peginterferon Lambda for the Treatment of COVID-19 |
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| Active, not recruiting | 3 | 763 | Canada | Peginterferon Lambda-1A, Placebo | University Health Network, Toronto | Sars-CoV2, Covid19 | 03/22 | 06/22 | | |
| Completed | 3 | 407 | Europe, Canada, US, RoW | Lonafarnib, EBP994, Sarasar, LNF, Ritonavir, Norvir, RTV, PEG IFN-alfa-2a, Pegasys, pegylated interferon-alfa, Placebo Lonafarnib, Placebo Ritonavir | Eiger BioPharmaceuticals | Hepatitis Delta Virus | 10/22 | 03/23 | | |
| Completed | 2 | 157 | Canada, RoW | Peginterferon Lambda-1A, placebo | University Health Network, Toronto, Michael Garron Hospital | Sars-CoV2, Covid-19 | 08/22 | 12/22 | | |
B-Fine, NCT04544956: A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B |
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| Completed | 2 | 12 | Europe, Canada, US | GSK3228836, Nucleos(t)ide therapy | GlaxoSmithKline | Hepatitis B | 11/23 | 11/23 | | |
NCT06216470: Vaccinal Effect of HBsAg Monoclonal Ab VIR-3434 in Chronic Hepatitis B Infection [VISION] |
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| Recruiting | 2 | 15 | Canada | VIR-3434 | University Health Network, Toronto | Hepatitis B, Chronic | 12/29 | 12/29 | | |
| Recruiting | 2 | 450 | Europe, Canada, Japan, US, RoW | Bepirovirsen, Placebo | GlaxoSmithKline, GlaxoSmithKline Research & Development Limited | Hepatitis B | 02/29 | 02/29 | | |
| Completed | N/A | 124 | Canada, US | Test and treat plus peer mentors, On-site treatment with peer support HCV treatment implementation strategy, Usual care, Standard of care referral HCV treatment implementation strategy | Johns Hopkins University, AbbVie | Hepatitis C Virus Infection, Response to Therapy of | 02/24 | 09/24 | | |
| Downar, Jonathan |
NCT03674671: Ketamine Versus Electroconvulsive Therapy in Depression |
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| Suspended | 3 | 240 | Canada | Intravenous Ketamine, Ketalar, Electroconvulsive Therapy, ECT | University of Ottawa, McGill University, Queen's University, University Health Network, Toronto, Ontario Shores Centre for Mental Health Sciences | Depressive Disorder, Major, Bipolar Depression | 12/25 | 12/25 | | |
NCT04376697: Repetitive Transcranial Magnetic Stimulation Trajectory of Outcomes Study |
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| Recruiting | N/A | 50 | Canada | Repetitive Transcranial Magnetic Stimulation (rTMS) | University Health Network, Toronto, Centre for Addiction and Mental Health | Depressive Disorder | 12/20 | 12/21 | | |
| Completed | N/A | 68 | Canada | active tDCS + mindfulness meditation, Soterix tDCS mini-Clinical Trials system (mini-CT) - active, sham tDCS + mindfulness meditation, Soterix tDCS mini-Clinical Trials system (mini-CT) - sham | Centre for Addiction and Mental Health, University Health Network, Toronto | Major Depressive Disorder | 08/20 | 08/20 | | |
NCT04257227: Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness |
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| Recruiting | N/A | 15 | Canada | repetitive Transcranial Magnetic Stimulation (rTMS), intermittent theta burst stimulation (iTBS) | Ottawa Hospital Research Institute, Lotte & John Hecht Memorial Foundation, Bruyere Research Institute, Canadian Cancer Society (CCS) | Depressive Symptoms, Depression, Anxiety, Psychological Distress, Terminal Illness | 01/25 | 01/25 | | |
| Enrolling by invitation | N/A | 5000 | US | Ampa One TMS System | Biomedical Discoveries and Neuroscientific Foundations LLC | Major Depressive Disorder, MDD, Generalized Anxiety Disorder, GAD, Depression, Anxiety | 08/28 | 12/29 | | |
| Price, Jennifer AD |
| Completed | N/A | 124 | Canada, US | Test and treat plus peer mentors, On-site treatment with peer support HCV treatment implementation strategy, Usual care, Standard of care referral HCV treatment implementation strategy | Johns Hopkins University, AbbVie | Hepatitis C Virus Infection, Response to Therapy of | 02/24 | 09/24 | | |
NCT03734393: HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients |
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| Active, not recruiting | N/A | 80 | US | HIVD+/R+ | Johns Hopkins University, National Institute of Allergy and Infectious Diseases (NIAID) | Hiv | 04/25 | 06/25 | | |
NCT04795219: Prevalence and Predictors of Hepatic Steatosis in Persons Living With HIV |
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| Recruiting | N/A | 1250 | US | | University of California, San Francisco, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | NAFLD, NAFLD-HIV, Hiv | 01/25 | 01/25 | | |
NCT05023044: Nonalcoholic Fatty Liver Disease in HIV Database |
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| Recruiting | N/A | 400 | US | | Johns Hopkins University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | NAFLD, NASH - Nonalcoholic Steatohepatitis, Hiv | 01/26 | 01/26 | | |
SMaRT, NCT05543720: Evaluation of Nurse-led Integrated Care of Complex Patients Facilitated By Telemonitoring: The Study |
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| Recruiting | N/A | 350 | Canada | Medly | University Health Network, Toronto, Markham Stouffville Hospital, William Osler Health System, Health Sciences North, Women's College Hospital | Heart Failureļ¼Congestive, Mental Health (Depression), Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, Hypertension | 09/25 | 09/25 | | |
| Kwok, Julian |
LIFUS-POT, NCT05547620: Modulating Cerebellar Activity With Low-intensity Focused Ultrasound Stimulation for Primary Orthostatic Tremor |
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| Recruiting | N/A | 15 | Canada | LIFUS Online Real, LIFUS Online Sham, LIFUS Offline | University Health Network, Toronto, National Organization for Rare Disorders | Orthostatic Tremor | 09/24 | 09/24 | | |
| Recruiting | N/A | 25 | Canada | TUS Active, TUS Sham | University Health Network, Toronto | Parkinson Disease, Essential Tremor, Dystonia | 06/24 | 06/24 | | |
tbFUS-FES_PD, NCT06090292: Effects of Peripheral Electrical Stimulation With Focused Ultrasound on Motor Symptoms in Parkinson's Patients |
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| Recruiting | N/A | 15 | Canada | Real TUS, Real FES, Sham TUS, Sham FES | University Health Network, Toronto | Parkinson Disease | 12/24 | 06/25 | | |
