University of Virgini
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 1 Trial 
6 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Slingluff, Craig L
MEL60, NCT02126579: Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists

Completed
1/2
50
US
Peptide Vaccine (LPV7) + Tetanus peptide, PolyICLC, Resiquimod, IFA
Craig L Slingluff, Jr, University of Virginia
Melanoma, Metastatic Melanoma, Mucosal Melanoma
11/19
05/21
Mel-65, NCT03617328: Vaccination With 6MHP, With or Without Systemic CDX-1127, in Patients With Stage II-IV Melanoma

Completed
1/2
33
US
6MHP, 6 melanoma helper peptide vaccine, Montanide ISA-51, polyICLC, CDX-1127, Varlilumab
Craig L Slingluff, Jr, Celldex Therapeutics
Melanoma
01/24
01/24
Mel66, NCT04364230: Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma)

Completed
1/2
22
US
6MHP, 6 melanoma helper peptide vaccine, NeoAg-mBRAF, BRAF 585-614 (V600E), PolyICLC, CDX-1140
Craig L Slingluff, Jr, Celldex Therapeutics
Melanoma, Ocular Melanoma, Uveal Melanoma
03/24
03/24
AM-003, NCT04116320: Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid Tumors

Active, not recruiting
1
5
US
Echopulse, Focused Ultrasound Ablation, FUSA, Poly ICLC, Hiltonol, Standard of Care PD-1 Therapy
Craig L Slingluff, Jr, Theraclion
Melanoma, Breast Cancer, Merkel Cell Carcinoma, Squamous Cell Cancer, Non Small Cell Lung Cancer, Cervical Cancer, Urothelial Carcinoma, Ovarian Cancer, Hepatocellular Carcinoma, Small-cell Lung Cancer, Microsatellite Instability High, Gastric Cancer, Esophageal Cancer
02/24
02/24
Mel61, NCT02382549: A Clinical Trial to Evaluate a Melanoma Helper Peptide Vaccine Plus Dabrafenib and Trametinib

Terminated
1
8
US
BRAF inhibitor, 6MHP, 6 melanoma helper peptide vaccine, MEK inhibitor
Craig L Slingluff, Jr, National Cancer Institute (NCI)
Melanoma
02/22
02/22
EXCILYNT, NCT05839912: Excision of Lymph Node Trial () (Mel69)

Recruiting
N/A
66
US
Excision of clinically detected lymph node metastasis before any systemic therapy, Excision of clinically detected lymph node metastasis after neoadjuvant systemic therapy
Craig L Slingluff, Jr
Melanoma
09/28
09/28

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