Timone University Hospital
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 11 Trials 
17 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
DUFFAUD, Florence
MULTISARC, NCT03784014: Molecular Profiling of Advanced Soft-tissue Sarcomas

Active, not recruiting
3
603
Europe
Nilotinib, TASIGNA, Ceritinib, ZYKADIA, Capmatinib, Lapatinib, TYVERB, Trametinib, MEKINIST, Trametinib and Dabrafenib, MEKINIST and TAFINLAR, Olaparib and Durvalumab, LYNPARZA, MEDI4736, Palbociclib, IBRANCE, PD-0332991, Glasdegib, PF-04449913, TAS-120, Next Generation sequencing exome, RNA Seq, NGS, High throughput sequencing
Institut National de la Santé Et de la Recherche Médicale, France, Commissariat A L'energie Atomique, Institut Bergonié, Plateforme labellisée Inca - Institut Bergonié, Bordeaux, Plateforme labellisée Inca - Hôpital Européen Georges Pompidou, Paris, EUCLID Clinical Trial Platform
Soft Tissue Sarcoma
12/23
10/25
CHIC-STS01, NCT04307277 / 2019-003014-13: Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma

Recruiting
3
600
Europe
Standard of care + chemotherapy, Standard of care
Institut Claudius Regaud, Direction Générale de l’Offre de Soins (DGOS)
Soft Tissue Sarcoma
10/32
10/32
ImadGist, NCT02260505 / 2013-001372-37: Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)

Completed
3
136
Europe
Imatinib maintenance, Glivec, Imatinib mésilate
Centre Leon Berard, INCA
Gastrointestinal Stromal Tumors, Resected Gastrointestinal Stromal Tumors, Non-metastatic, High Risk of Recurrence, KIT Gene Mutation
12/23
12/23
LENVAGIST, NCT04193553: Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure

Completed
2
77
Europe
Lenvatinib, Placebo, Best supportive care
Centre Leon Berard
Gastro Intestinal Stromal Tumour
01/24
04/24
ChonDRAgon, NCT04950075: Study of INBRX-109 in Conventional Chondrosarcoma

Recruiting
2
201
Europe, US, RoW
INBRX-109, Placebo
Inhibrx Biosciences, Inc
Conventional Chondrosarcoma
09/25
12/26
EREMISS, NCT03793361: Phase II Study of Regorafenib as Maintenance Therapy

Completed
2
127
Europe
Regorafenib, stivarga, Placebo
Centre Oscar Lambret
Metastatic Soft Tissue Sarcoma
03/24
09/24
PEMBROCABOSARC, NCT05182164 / 2020-002366-13: Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas

Recruiting
2
119
Europe
Association of pembrolizumab + cabozantinib
Institut Bergonié, Ipsen, MSD France
Soft Tissue Sarcoma Adult, Advanced Soft-tissue Sarcoma, Ewing Sarcoma, Osteosarcoma, Undifferentiated Pleomorphic Sarcoma
04/24
10/25
BFR-ESS, NCT03624244: Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)

Recruiting
2
40
Europe
Aromatase Inhibitors, ANASTRAZOLE, ARIMIDEX, AROMASINE, EXEMESTANE, FEMARA, LETROZOLE
Centre Leon Berard
Low Grade Endometrial Stromal Sarcoma
01/25
01/28
ATEZOGIST, NCT05152472: A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments

Recruiting
2
110
Europe
Atezolizumab 1200 mg, Tecentriq®, Imatinib 400 MG, Glivec®
Centre Leon Berard
Unresectable Gastrointestinal Stromal Tumor (GIST), Locally Advanced Gastrointestinal Stromal Tumor (GIST), Metastatic Gastrointestinal Stromal Tumor
10/27
10/27
L-UteCIN, NCT06524583: Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumour

Not yet recruiting
2
198
Europe
Doxorubicin, Trabectedin, Yondelis
UNICANCER, PharmaMar, Ligue contre le cancer, France, National Research Agency, France, University Hospital, Marseille, Institut Claudius Regaud, Institut Bergonié, Oncopole
Leiomyosarcoma Uterus
12/29
12/30
REGOBONE, NCT02389244 / 2013-003910-42: A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas

Checkmark Data from REGOBONE trial for relapsed advanced or metastatic chordoma at ESMO 2021
Jul 2021 - Jul 2021: Data from REGOBONE trial for relapsed advanced or metastatic chordoma at ESMO 2021
Active, not recruiting
2
163
Europe
Regorafenib, Stivarga, Placebo, Placebo tablet
UNICANCER
Ewing Sarcomas, Chondrosarcomas, Osteosarcomas, Chondroma, CIC-Rearranged Sarcoma
10/24
06/25
AMPHISARC, NCT05180695: HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas

Recruiting
1/2
58
Europe
Pazopanib, Votrient, HDM201, siremadlin
Centre Leon Berard, Novartis, National Cancer Institute, France
Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma
01/26
07/26
COTESARC, NCT04216953: MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma

Active, not recruiting
1/2
320
Europe
Cobimetinib, GDC-0973, Atezolizumab, RO5541267
Centre Leon Berard
Sarcoma,Soft Tissue
02/26
02/27
NEOSarcomics, NCT02789384: CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study.

Recruiting
N/A
205
Europe
Procedure/Surgery
Institut Bergonié, National Cancer Institute, France, Ministry of Health, France
Soft-tissue Sarcomas
01/25
08/27
REGOSTA, NCT04055220 / 2018-004045-16: Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas

Recruiting
N/A
168
Europe
Treatment by Regorafenib, Stivarga, Treatment by Placebo, Standard of care
Centre Leon Berard
Bone Sarcoma, Osteosarcoma, Ewing Sarcoma, Chondrosarcoma, Undifferentiated Pleomorphic Sarcoma, Leiomyosarcoma, Angiosarcoma
10/26
10/26
CRYODESMO-02, NCT06081400: Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting

Recruiting
N/A
150
Europe
Cryoablation, Chemotherapy drug
University Hospital, Strasbourg, France, Direction Générale de l'Offre des Soins (DGOS)
Desmoid Tumor
03/27
06/29
OPTISARC, NCT05272358: Economic Evaluation of Sarcoma Patients Management in France

Recruiting
N/A
2431
Europe
NETSARC network
Centre Leon Berard, École nationale supérieure des Mines Saint-Etienne France, Rennes University Hospital, Assistance Publique - Hôpitaux de Paris
Sarcoma
06/22
02/24

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