Yale University School of Medicine: Yale Stress Center
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 5 Trials 
10 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Sinha, Rajita
NCT03980184: Guanfacine to Improve Substance Use Outcomes in Women

Completed
2
74
US
Guanfacine, Tenex,, Behavioral Counseling, Manualized Drug Counseling
Yale University, National Institute on Drug Abuse (NIDA)
Substance Use Disorders
11/22
11/22
SICA 2, NCT05322941: Effect of AEF0117 on Treatment-seeking Patients With Cannabis Use Disorder (CUD)

Completed
2
333
US
AEF0117, 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one, Placebo oral capsule, Placebo
Aelis Farma, National Institute on Drug Abuse (NIDA)
Marijuana Abuse
04/24
07/24
NCT05781009: Pregnenolone for the Treatment of Alcohol Use Disorder

Recruiting
2
150
US
Pregnenolone, Placebo
Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder
07/28
07/28
NCT04793685: Prazosin for Alcohol Use Disorder With Withdrawal Symptoms

Recruiting
1/2
150
US
Prazosin, Minipress, 12-Step Facilitation with Relapse Prevention and Contingency Management
Yale University
Alcohol Withdrawal
06/26
06/27
NCT04226690: Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products

Completed
1
24
US
Active CBD/THC Dose 1, Medical marijuana medicine, Active CBD/THC Dose 2, matched placebo comparator, Placebo
Yale University, Connecticut Pharmaceutical Solutions
Pain
12/23
12/23
NCT05447286: Safety, Tolerability and Pharmacokinetics of NYX-783 and Oxycodone DDI Study

Active, not recruiting
1
9
US
NYX-783, ((2S, 3R)-3-hydroxy-2-((S)-5-isobutyryl-1-oxo-2,5-diazaspiro[3.4]octan-2-yl)butanamide), Placebo, Oxycodone
Yale University, National Institute on Drug Abuse (NIDA), Aptinyx
Opioid Use Disorder
12/24
12/24
NCT04779697: GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight

Active, not recruiting
1
96
US
GLP-1 analogue - semaglutide, Semaglutide, Placebo
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
01/25
06/25
NCT02616094: Multimodal Neuroimaging of Stress and Reward Cues to Assess Alcoholism Risk and Relapse

Completed
N/A
224
US
Multi-method Neuroendocrine and Neuroimaging Procedure Scan 1, Multi-method Neuroendocrine and Neuroimaging Procedure Scan 2
Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Dependence
06/22
06/22
NCT04419831: Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning and Executive Function

Completed
N/A
81
US
Yale Stress Pain Test (YSPT)
Yale University
Pain Response, Stress, Trauma
12/23
12/23
NCT03950453: Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention

Active, not recruiting
N/A
246
US
Parenting Mindfully for Health Nutrition (PMH), Contact Control Nutrition (C+N), Non-randomized historical control (WLC) assessment only, assessment only group
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Child Obesity
06/23
10/24

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