| Roblin, Xavier |
VEDO-PREDIRESP, NCT02768532: Value of Pharmacokinetic Assays in the Prediction of Induction and Maintenance Therapeutic Response in Crohn's Disease |
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| Terminated | 4 | 47 | Europe | Vedolizumab, Entyvio | Centre Hospitalier Universitaire de Saint Etienne, Theradiag, Takeda | Crohn Disease | 01/22 | 01/23 | | |
ACTIVE, NCT02425852: A Randomized, Multicenter Open Label Study Comparing Early Administration of Azathioprine Plus IFX to Steroids Plus Azathioprine for Acute Severe Colitis |
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| Completed | 4 | 65 | Europe | Azathioprine, Infliximab, Prednisolone, Hydrocortisone | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | Ulcerative Colitis | 06/22 | 01/23 | | |
| Active, not recruiting | 4 | 33 | Europe | Ustekinumab, Stelara, Placebo | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives, Janssen, LP | Crohn's Disease | 06/25 | 12/25 | | |
| Active, not recruiting | 4 | 150 | Europe | Infliximab, Infliximab injection, Vedolizumab Injection, Vedolizumab | Rennes University Hospital | Ulcerative Colitis | 12/24 | 05/25 | | |
VEDIAN, NCT06180382: Comparison of Vedolizumab Treatment to Adalimumab Dose Intensification in Crohn's Disease Patients With Loss of Response or Biomarker Activity to Adalimumab on First Line With Therapeutic Drug Concentration. |
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| Recruiting | 4 | 220 | Europe | Adalimumab, Vedolizumab | Centre Hospitalier Universitaire de Saint Etienne, Takeda France | Crohn's Disease | 01/26 | 01/27 | | |
| Active, not recruiting | 4 | 672 | Europe, Canada, US, RoW | Treatment Algorithm A, vedolizumab, Treatment Algorithm B, Treatment Algorithm C | Alimentiv Inc., Takeda Development Center Americas, Inc. | Colitis, Ulcerative | 03/26 | 03/26 | | |
NCT04183608 / 2018-003490-10: A Trial COmparing staNdard of Care Versus Treat to Target With telemonitoRing and Patient Education in Patients With Ulcerative cOlitis Initiating Adalimumab |
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| Recruiting | 4 | 238 | Europe | Adalimumab, Calprotectin, e-Monitoring, Therapy Education | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives, AbbVie | Ulcerative Colitis | 04/25 | 05/28 | | |
COMET, NCT05040464: Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial |
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| Recruiting | 3 | 166 | Europe | AZA capsules, MTX, blood sample | Centre Hospitalier Universitaire, Amiens | Crohn Disease, Azathioprine, Methotrexate | 08/23 | 03/24 | | |
CYTOVEDO, NCT04064697: Impact of Anti-cytomegalovirus Treatment in the Management of Relapsing Ulcerative Colitis Requiring Vedolizumab Therapy |
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| Terminated | 3 | 6 | Europe | Valganciclovir, antiviral therapy | Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France | Ulcerative Colitis, Unspecified | 11/23 | 02/24 | | |
| Recruiting | 3 | 612 | Europe, Canada, US, RoW | ABX464, Obefazimod, Placebo | Abivax S.A. | Ulcerative Colitis | 03/25 | 04/25 | | |
LUCENT-URGE, NCT05767021: A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis |
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| Active, not recruiting | 3 | 160 | Europe, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis, Ulcerative Colitis Chronic | 08/24 | 09/25 | | |
| Recruiting | 3 | 1050 | Europe, Canada, Japan, US, RoW | ABX464, Obefazimod, Placebo | Abivax S.A. | Ulcerative Colitis | 01/26 | 01/30 | | |
| Recruiting | 3 | 1063 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis | 07/26 | 12/27 | | |
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PneumoMICI, NCT02255227: Anti-pneumococcal Vaccine Strategy in Patients Treated With Immunosuppressants or Biotherapies for CIBD |
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| Terminated | 2b | 104 | Europe | Prevenar 13, Pneumo 23 | Centre Hospitalier Universitaire de Saint Etienne, Pfizer | Infections, Pneumococcal, Bowel Diseases, Inflammatory | 08/19 | 07/22 | | |
NCT06233461: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease |
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| Recruiting | 2 | 268 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Crohn's Disease | 09/26 | 07/27 | | |
| Active, not recruiting | 2 | 357 | Europe, Canada, US | TAK-062, Simulated Inadvertent Gluten Exposure (SIGE) Gluten-Bar, TAK-062 Placebo, Simulated Inadvertent Gluten Exposure (SIGE) Gluten-free Bar | Takeda | Celiac Disease | 05/25 | 05/25 | | |
| Terminated | N/A | 67 | Europe | Blood sample, Rectosigmoidoscopy | Centre Hospitalier Universitaire de Saint Etienne, Takeda, Theradiag | Ulcerative Colitis | 04/22 | 06/22 | | |
RECOHFERRON, NCT04030676: QuantiFERON-CMV Test in a Prediction for Colic Cytomegalovirus Reactivation During Ulcerative Colitis |
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| Recruiting | N/A | 196 | Europe | Biopsies, Blood samples | Centre Hospitalier Universitaire de Saint Etienne | Cytomegalovirus Infections | 01/26 | 04/26 | | |
VIRCH, NCT03172195: Detection of Herpesvirus DNA (CMV, EBV, HHV-6 and HSV) in Colonic Tissue: Impact on Ulcerative Colitis Flare-up |
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| Active, not recruiting | N/A | 80 | Europe | rectosigmoidoscopy, biopsies, blood sample | Centre Hospitalier Universitaire de Saint Etienne | Colitis, Ulcerative | 03/24 | 03/25 | | |
SPACIFIX, NCT03841942: Comparison of Trough Level- and Clinical-based Spacing of Infliximab Infusions in Patients With IBD in Deep Remission |
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| Terminated | N/A | 64 | Europe | clinically-based spacing strategy, Trough level-based strategy | University Hospital, Montpellier | Inflammatory Bowel Diseases | 10/23 | 10/23 | | |
| Recruiting | N/A | 210 | Europe | Magnetic Resonance Enterography (MRE) | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | Crohn Disease | 07/25 | 08/25 | | |
| Not yet recruiting | N/A | 216 | Europe | Sleep activity, Questionnaires | Hospices Civils de Lyon | Disease Bowel, Crohn Disease, Ulcerative Colitis | 01/28 | 01/28 | | |
Deeper, NCT04973423: STUDY OF THE ADDED VALUE OF A TRANSMURAL EVALUATION IN PATIENTS WITH CROHN'S DISEASE UNDER BIOTHERAPY WITH CLOSE FECAL CALPROTECTIN FOLLOW-UP |
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| Recruiting | N/A | 180 | Europe | MRI | University Hospital, Clermont-Ferrand | Crohn Disease, Calprotectin, MRI | 03/27 | 08/27 | | |
| Walczak, Piotr |
| Active, not recruiting | 4 | 672 | Europe, Canada, US, RoW | Treatment Algorithm A, vedolizumab, Treatment Algorithm B, Treatment Algorithm C | Alimentiv Inc., Takeda Development Center Americas, Inc. | Colitis, Ulcerative | 03/26 | 03/26 | | |
| Recruiting | 3 | 1063 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis | 07/26 | 12/27 | | |
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| Ras, Magdalena |
| Active, not recruiting | 4 | 672 | Europe, Canada, US, RoW | Treatment Algorithm A, vedolizumab, Treatment Algorithm B, Treatment Algorithm C | Alimentiv Inc., Takeda Development Center Americas, Inc. | Colitis, Ulcerative | 03/26 | 03/26 | | |
