| Polin, Richard |
| Recruiting | 4 | 802 | Canada, US | Ampicillin, Gentamycin, Normal saline | Michael Morowitz, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal | 09/26 | 06/27 | | |
| Ali, Syed |
NCT01041703: Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia |
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| Recruiting | 3 | 747 | US, RoW | clofarabine, cytarabine, daunorubicin hydrochloride, decitabine | Eastern Cooperative Oncology Group, National Cancer Institute (NCI) | Leukemia | 02/19 | | | |
SCALP2, NCT05914805: A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss |
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| Recruiting | 3 | 726 | Europe, US | Clascoterone 5% solution, CB-03-01 5% solution, Vehicle solution, Vehicle | Cassiopea SpA, Ergomed PLC, Pharmapace Inc, Canfield Scientific Inc., ICON Clinical Research | Alopecia, Androgenetic | 08/24 | 03/25 | | |
NCT03376477: Allogeneic Myeloma GM-CSF Vaccine With Lenalidomide in Multiple Myeloma Patients in Complete or Near Complete Remission |
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| Active, not recruiting | 2 | 54 | US | GM-CSF vaccine, GVAX, Lenalidomide, Revlimid, Prevnar13, pneumococcal vaccine, Placebo Prevnar13, Placebo GM-CSF Vaccine | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Celgene, Aduro Biotech, Inc. | Multiple Myeloma | 01/24 | 12/24 | | |
NCT05772520: The Efficacy and Safety of TLL018 in Moderate-to-severe Plaque Psoriasis |
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| Completed | 2 | 82 | US | TLL018 tablets, TLL018 Placeboes | Hangzhou Highlightll Pharmaceutical Co., Ltd | Plaque Psoriasis | 12/24 | 12/24 | | |
NCT04843241: Translation of Neck Disability Index Into Local Pakistani Languages of Pakistan |
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| Recruiting | N/A | 500 | RoW | | Riphah International University | Neck Pain | 12/21 | 12/21 | | |
nHFOV, NCT04914715: Versus Invasive Conventional Ventilation for Preterm Neonates With Respiratory Distress Syndrome |
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| Withdrawn | N/A | 1200 | RoW | Non-invasive High Frequency Oscillatory Ventilation, Conventional Invasive Ventilation | Indus Hospital and Health Network | Respiratory Distress Syndrome in Premature Infant | 06/23 | 12/23 | | |
CAMEO, NCT04076813: Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry |
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| Recruiting | N/A | 4000 | US | | Chiesi USA, Inc., Duke University | Myocardial Infarction | 10/24 | 10/24 | | |
NCT06267404: Effectiveness of Iliopsoas Positional Release Versus Conventional Exercises in the Management of Sub-acute Back Pain. |
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| Recruiting | N/A | 100 | RoW | Iliopsoas Positional release therapy, Strain Counter-strain therapy, Conventional exercises, conventional physical therapy treatment | University of Karachi, Sindh Institute of Physical Medicine and Rehabilitation | Back Pain | 02/25 | 02/25 | | |
| Kirtane, Ajay |
| Active, not recruiting | N/A | 282 | Europe, US | The Paradise® Renal Denervation Ultrasound System, renal denervation, Sham Procedure, renal angiogram | ReCor Medical, Inc. | Hypertension, Vascular Diseases | 09/20 | 05/25 | | |
RADIANCE-II, NCT03614260: The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension |
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| Active, not recruiting | N/A | 225 | Europe, US | Paradise Renal Denervation System, Renal Angiogram, Renal Denervation | ReCor Medical, Inc. | Hypertension, Vascular Diseases, Cardiovascular Diseases | 12/22 | 07/27 | | |
CAMEO, NCT04076813: Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry |
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| Recruiting | N/A | 4000 | US | | Chiesi USA, Inc., Duke University | Myocardial Infarction | 10/24 | 10/24 | | |
NCT05372679: REDUCED 1 - Renal Denervation Using Ultrasonic Catheter EmitteD Energy Study / |
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| Active, not recruiting | N/A | 25 | US | Renal denervation | SoniVie Inc. | Uncontrolled Stage 2 Hypertension | 12/25 | 12/25 | | |
| Recruiting | N/A | 2000 | Europe, Canada, US, RoW | | Minneapolis Heart Institute Foundation | Coronary Artery Disease | 01/24 | 01/24 | | |
| Active, not recruiting | N/A | 15 | Europe, US | VITALYST System, Percutaneous Mechanical Circulatory Support | Boston Scientific Corporation | High-risk Percutaneous Coronary Intervention, Heart Disease, Coronary | 10/24 | 01/25 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
ECLIPSE, NCT03108456: Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The Trial |
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| Active, not recruiting | N/A | 2005 | US | Orbital Atherectomy, Balloon | Abbott Medical Devices, Cardiovascular Research Foundation, New York | Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction | 06/24 | 06/25 | | |
| Recruiting | N/A | 1000 | US | Paradise Ultrasound Renal Denervation Treatment, Paradise Ultrasound RDN | ReCor Medical, Inc. | Hypertension, Cardiovascular Diseases, Vascular Diseases | 09/26 | 07/31 | | |
THRIVE, NCT06559891: - THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension |
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| Recruiting | N/A | 261 | US | TIVUS™ Renal Denervation System, Renal Denervation, Sham | SoniVie Inc., NAMSA, European Cardiovascular Research Center | Hypertension | 10/25 | 08/28 | | |
| Recruiting | N/A | 1924 | Europe, Japan, US, RoW | FFRangio, FFR or NHPR, FFR, iFR RFR, dPR, Pd/Pa | CathWorks Ltd., Cardiovascular Research Foundation, New York | Percutaneous Coronary Intervention | 12/24 | 12/24 | | |
| Recruiting | N/A | 492 | US | Sirolimus Drug Coated Balloon, Plan balloon Angioplasty (POBA) | Concept Medical Inc., Cardiovascular Research Foundation, New York | In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease | 09/25 | 02/28 | | |
| Active, not recruiting | N/A | 300 | US | Renal Denervation | ReCor Medical, Inc. | Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases | 12/28 | 12/28 | | |
| Askanase, Anca D |
| Completed | 4 | 8 | US | CellCept, Mycophenolate Mofetil, ACTHar gel, ACTHar, H.P. ACTHar Gel, Repository corticotropin | Columbia University | Lupus Nephritis | 01/24 | 01/24 | | |
| Recruiting | 2/3 | 474 | Europe, Canada, Japan, US, RoW | Litifilimab, BIIB059, Placebo | Biogen, Biogen Idec Research Limited | Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus | 10/26 | 12/27 | | |
DIVERT, NCT05306873: Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus |
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| Terminated | 2 | 9 | US | Mycophenolate Mofetil, CellCept, MMF, Placebo for Mycophenolate Mofetil, Voclosporin, Lupkynis, Lupkynis(TM), Placebo for Voclosporin | National Institute of Allergy and Infectious Diseases (NIAID) | Systemic Lupus Erythematosus | 04/24 | 04/24 | | |
| Recruiting | 2 | 74 | US | VIB4920, Placebo for VIB4920 | National Institute of Allergy and Infectious Diseases (NIAID) | Lupus Nephritis | 08/26 | 03/27 | | |
RESET-SLE, NCT06121297: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus |
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| Recruiting | 1/2 | 12 | Europe, US | CABA-201 | Cabaletta Bio | Systemic Lupus Erythematosus, Lupus Nephritis | 12/27 | 12/27 | | |
| Recruiting | 1 | 20 | US | Anifrolumab, Medi 546, Standard of Care, azathioprine, methotrexate, mycophenolate mofetil, corticosteroids, antimalarials | Oklahoma Medical Research Foundation, NYU Langone Health, Yale University, Piedmont Heart Institute, Inc., Atlanta, GA, Columbia University | Systemic Lupus Erythematosus (SLE) | 12/23 | 12/24 | | |
AAAV0505, NCT06518668: A Study of NKX019, a CD19 CAR NK Cell Therapy, in Subjects With Systemic Lupus Erythematosus |
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| Recruiting | 1 | 6 | US | NKX019, NKX019 infusion, Cyclophosphamide LD, Cy | Columbia University | Systemic Lupus Erythematosus | 12/26 | 12/40 | | |
| Musat, Claudia |
| Recruiting | 3 | 198 | US | GIE Medical ProTractX3 TTS DCB, Control | GIE Medical | Esophageal Stricture | 07/25 | 12/29 | | |
| Recruiting | 3 | 171 | US | GIE Medical ProTractX3 TTS DCB, Control | GIE Medical | Bowel; Stricture | 09/24 | 03/29 | | |
| Active, not recruiting | N/A | 30 | US | penetrating atherosclerotic ulcer, aorta branch cardiovascular implant, Relay Branch System, system, endovascular graft, aortic aneurysm treatment | Bolton Medical | Thoracic Aorta Aneurysm, Aneurysm, Ruptured, Aortic Aneurysm | 09/23 | 08/28 | | |
| Active, not recruiting | N/A | 115 | US | AMDS | Artivion Inc., Syneos Health | Acute Aortic Dissection | 12/23 | 12/29 | | |
NCT06029660: AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion |
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| Recruiting | N/A | 180 | Europe, US, RoW | IMPEDE-FX RapidFill Implants, EndoVascular Aneurysm Repair, EVAR | Shape Memory Medical, Inc., NAMSA | Aortic Aneurysm, Abdominal | 06/27 | 06/31 | | |
| Mendez, Juan |
NCT05640401: Holographic Screens as a Replacement of Monitors During GI Endoscopies |
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| Recruiting | N/A | 10 | RoW | Endoscopy guided by mixed reality (HoloLens2TM) (HXtend™ software) | Instituto Ecuatoriano de Enfermedades Digestivas, EndoscopyNet, Quito, Ecuador, mdconsgroup, Guayaquil, Ecuador | Gastrointestinal Diseases | 10/23 | 10/23 | | |
CAMEO, NCT04076813: Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry |
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| Recruiting | N/A | 4000 | US | | Chiesi USA, Inc., Duke University | Myocardial Infarction | 10/24 | 10/24 | | |
| Randis, Tara |
| Recruiting | 4 | 802 | Canada, US | Ampicillin, Gentamycin, Normal saline | Michael Morowitz, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal | 09/26 | 06/27 | | |
| Not yet recruiting | 3 | 802 | Canada, US | Ampicillin, Gentamicin, Placebo | Sharp HealthCare, University of Pittsburgh, Morgan Stanley Children's Hospital, University of Louisville, Sharp Mary Birch Hospital for Women & Newborns, Children's Hospital of Philadelphia, Jefferson Medical College of Thomas Jefferson University, University of South Florida, Westchester Medical Center, Yale University, The University of Texas Health Science Center at San Antonio, Penn State University, State University of New York - Downstate Medical Center, Mount Sinai Hospital, Canada | Premature Birth, Antibiotics, Neurodevelopment | 03/29 | 03/29 | | |
| Beauchemin, Melissa P |
| Completed | 3 | 445 | Canada, US | SPARK Symptom Screening Linked to Feedback to Providers | The Hospital for Sick Children, National Cancer Institute (NCI) | Pediatric Cancer, Quality of Life | 10/23 | 10/23 | | |
| Recruiting | N/A | 60 | US | Needs navigation intervention | Columbia University | Cancer in Adolescence | 02/25 | 05/25 | | |
NCT06072833: Characterizing and Addressing Financial Toxicity in AYAs with Cancer |
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| Recruiting | N/A | 216 | US | Patient Financial Education / Navigation | Columbia University, Patient Advocate Foundation | Cancer in Adolescence | 03/25 | 06/25 | | |
| Recruiting | N/A | 30 | US | BMT4me | Nationwide Children's Hospital, Columbia University | Bone Marrow Transplant | 05/26 | 05/26 | | |
NCT04928599: Financial Distress During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States |
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| Active, not recruiting | N/A | 100 | US | Electronic Health Record Review, Interview, Survey Administration | Children's Oncology Group | Acute Lymphoblastic Leukemia | 03/27 | 03/28 | | |
| Bombacie, Michelle |
| Completed | 3 | 445 | Canada, US | SPARK Symptom Screening Linked to Feedback to Providers | The Hospital for Sick Children, National Cancer Institute (NCI) | Pediatric Cancer, Quality of Life | 10/23 | 10/23 | | |
| Jordan, Brianna |
| Completed | 3 | 445 | Canada, US | SPARK Symptom Screening Linked to Feedback to Providers | The Hospital for Sick Children, National Cancer Institute (NCI) | Pediatric Cancer, Quality of Life | 10/23 | 10/23 | | |
NCT02945800: Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma |
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| Active, not recruiting | 2 | 59 | US | nab-Paclitaxel, Abraxane, Gemcitabine, Gemzar | H. Lee Moffitt Cancer Center and Research Institute, National Pediatric Cancer Foundation | Osteosarcoma, Ewing Sarcoma, Rhabdomyosarcoma, Soft Tissue Sarcoma | 02/25 | 02/26 | | |
NCT04724421: Expanded Access Protocol for Adults and Pediatric Patients With Sickle Cell Disease Who Have No Alternative Treatment Options |
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| Available | N/A | | US, RoW | Voxelotor, GBT440 | Pfizer, Pfizer | Sickle Cell Disease | | | | |
