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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Kawakami, Atsushi
ARRIA, NCT06611696: Avacopan vs Reduced-dose Glucocorticoids in ANCA-associated Vasculitis	Recruiting	4	160	Japan	Avacopan, prednisolone and rituximab, Prednisolone and rituximab	Chiba University, Kissei Pharmaceutical Co., Ltd., International University of Health and Welfare	ANCA Associated Vasculitis (AAV)	03/27	09/28
TRANSFORM, NCT05090410: Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate	Recruiting	3	400	Japan	filgotinib 200mg/day, subcutaneous tocilizumab 162mg/biweekly	Atsushi Kawakami, Gilead Sciences	Rheumatoid Arthritis, JAK Inhibitor, IL-6 Inhibitor, Musculoskeletal Ultrasound, Biomarker	02/23	12/23
DOPPLER, NCT05121298: Discontinuation of Methotrexate in Rheumatoid Arthritis Patients Achieving Clinical Remission by Treatment With Upadacitinib Plus Methotrexate	Recruiting	3	155	Japan	upadacitinib 15mg/day	Atsushi Kawakami, AbbVie GK.	Rheumatoid Arthritis, JAK Inhibitor, Musculoskeletal Ultrasound, Biomarker	11/23	09/24
NCT05814159: A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)	Active, not recruiting	3	15	Japan	Anakinra, Kineret, Placebo	Swedish Orphan Biovitrum, CMIC Co, Ltd. Japan	Still's Disease, Juvenile Onset, Still's Disease, Adult-Onset	12/25	06/26
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Terminated	2	301	Europe, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25
NCT05411016: A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus	Recruiting	1	157	Japan, RoW	Placebo, KK4277	Kyowa Kirin Co., Ltd.	Healthy Volunteers, Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE)	12/24	12/25
Takenaka, Motoi
No trials found

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Kawakami, Atsushi
ARRIA, NCT06611696: Avacopan vs Reduced-dose Glucocorticoids in ANCA-associated Vasculitis	Recruiting	4	160	Japan	Avacopan, prednisolone and rituximab, Prednisolone and rituximab	Chiba University, Kissei Pharmaceutical Co., Ltd., International University of Health and Welfare	ANCA Associated Vasculitis (AAV)	03/27	09/28
TRANSFORM, NCT05090410: Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate	Recruiting	3	400	Japan	filgotinib 200mg/day, subcutaneous tocilizumab 162mg/biweekly	Atsushi Kawakami, Gilead Sciences	Rheumatoid Arthritis, JAK Inhibitor, IL-6 Inhibitor, Musculoskeletal Ultrasound, Biomarker	02/23	12/23
DOPPLER, NCT05121298: Discontinuation of Methotrexate in Rheumatoid Arthritis Patients Achieving Clinical Remission by Treatment With Upadacitinib Plus Methotrexate	Recruiting	3	155	Japan	upadacitinib 15mg/day	Atsushi Kawakami, AbbVie GK.	Rheumatoid Arthritis, JAK Inhibitor, Musculoskeletal Ultrasound, Biomarker	11/23	09/24
NCT05814159: A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)	Active, not recruiting	3	15	Japan	Anakinra, Kineret, Placebo	Swedish Orphan Biovitrum, CMIC Co, Ltd. Japan	Still's Disease, Juvenile Onset, Still's Disease, Adult-Onset	12/25	06/26
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Terminated	2	301	Europe, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25
NCT05411016: A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus	Recruiting	1	157	Japan, RoW	Placebo, KK4277	Kyowa Kirin Co., Ltd.	Healthy Volunteers, Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE)	12/24	12/25
Takenaka, Motoi
No trials found