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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Sperling, Michael
NCT06453213: Open-label Study of Cenobamate Monotherapy in Adult Subjects With Newly Diagnosed or Recurrent Partial-Onset Epilepsy	Recruiting	4	90	US	Cenobamate	SK Life Science, Inc.	Focal Onset Seizure	05/27	07/27
SKYWAY, NCT04938427 / 2021-002481-40: A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome	Completed	3	270	Europe, Canada, Japan, US, RoW	Placebo, Soticlestat, TAK-935	Takeda	Lennox Gastaut Syndrome (LGS)	01/24	01/24
ENDYMION 2, NCT05163314 / 2021-002482-17: A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome	Recruiting	3	400	Europe, Canada, Japan, US, RoW	Soticlestat, TAK-935	Takeda	Dravet Syndrome (DS), Lennox Gastaut Syndrome (LGS)	05/26	05/26
NCT04244175: A Trial of the Efficacy and Safety of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures	Completed	2	154	Europe, US, RoW	CVL-865, Placebo	Cerevel Therapeutics, LLC	Seizures	05/24	05/24
NCT05473442: Study of EQU-001 for Uncontrolled Focal Onset Seizures	Terminated	2	27	US, RoW	EQU-001, Matching Placebo	Equilibre Biopharmaceuticals B.V.	Focal Onset Seizures	07/23	07/23
MTLE, NCT05135091: FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy	Recruiting	1/2	40	US	NRTX-1001, GABA-secreting interneurons, Sham Comparator	Neurona Therapeutics, California Institute for Regenerative Medicine (CIRM)	Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis	05/25	05/26
NCT05738226: EpiCare@Home Validation Study for Focal Onset Seizures	Recruiting	N/A	80	US	EpiCare@Home, wearable multimodal seizure monitoring system	Byteflies, Thomas Jefferson University	Epilepsy, Seizures, Seizures, Focal, Seizure, Refractory	06/23	12/23
NCT02844465: Stereotactic Laser Ablation for Temporal Lobe Epilepsy (Slate)	Completed	N/A	167	US	Visualase MRI-Guided Laser Ablation, Visualase System, Visualase procedure, Laser interstitial thermal therapy, Stereotactic laser ablation	MedtronicNeuro	Temporal Lobe Epilepsy	12/23	12/23
NCT04286776: Memory Retrieval and Encoding Investigated by Neural Stimulation	Active, not recruiting	N/A	800	US	Direct electrical stimulation	University of Pennsylvania, National Institute of Neurological Disorders and Stroke (NINDS), Columbia University	Epilepsy Intractable	12/24	12/24