| Kabour, Ameer |
| Active, not recruiting | N/A | 1720 | Europe, Canada, US | Microport Firehawk stent, MicroPort Firehawk rapamycin target eluting stent, 2nd generation DES (XIENCE family, Promus family, Resolute/Onyx family/Endeavor, and Orsiro stent) | Shanghai MicroPort Medical (Group) Co., Ltd. | Coronary Artery Disease | 06/24 | 06/27 | | |
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy |
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| Recruiting | N/A | 620 | US | OPTIMIZER Smart System | Impulse Dynamics | Heart Failure | 03/26 | 03/26 | | |
| Davis, Jason T |
NCT04432259: Oral Dexamethasone as an Intervention for Postoperative Pain and Nausea Management in Total Knee Arthroplasty |
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| Not yet recruiting | 4 | 300 | NA | Dexamethasone, Placebo | Henry Ford Health System | Arthritis Knee, Postoperative Nausea, Postoperative Pain | 06/22 | 12/22 | | |
NCT04518670: Success in Comaneci-assist Coils Embolization Surveillance Study (SUCCESS) |
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| Active, not recruiting | N/A | 90 | US | Comaneci Embolization Assist Device | Rapid Medical | Intracranial Aneurysm | 05/24 | 07/24 | | |
| Recruiting | N/A | 168 | Europe, US | Tigertriever 13 | Rapid Medical | Ischemic Stroke, Neovascularization | 08/24 | 08/24 | | |
| Chowdhry, Shakeel |
NCT03235271: Pilot Study of Acute Stroke Using the Brainpulse™ |
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| Recruiting | N/A | 220 | US | BrainPulse Device | Jan Medical, Inc. | Stroke, Acute | 12/23 | 04/24 | | |
STAND, NCT04835428: - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients With Vertebral Compression Fractures |
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| Recruiting | N/A | 408 | US | Treatment Group: AGN1 LOEP SV Kit, Control Group: PMMA bone cement | AgNovos Healthcare, LLC | Vertebral Compression Fracture, Compression Fracture, Vertebral Compression | 12/25 | 12/27 | | |
| Recruiting | N/A | 40000 | Europe, Canada, Japan, US, RoW | Stroke/Thrombectomy/Aneurysm-specific surgical procedures | Medical University of South Carolina | Stroke, Thromboses, Intracranial, Aneurysm, Brain | 01/55 | 01/55 | | |
| Zaidat, Osama O |
PICASSO, NCT05611242: Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial |
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| Recruiting | 3 | 404 | US | MT+CAS with IV-AP, Thrombectomy, MT+CAS with PO-AP, MT+CAT with PO-AP | Mercy Health Ohio | Acute Ischemic Stroke | 03/26 | 05/26 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/27 | 05/27 | | |
| Completed | N/A | 298 | US | Next Generation Neuroform Stent System | Stryker Neurovascular | Intracranial Aneurysm | 12/21 | 09/22 | | |
TESLA, NCT03805308: The Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke |
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| Completed | N/A | 300 | US | Intra-arterial Therapy, Thrombectomy | Mercy Health Ohio | Ischemic Stroke | 02/23 | 11/23 | | |
NCT05018650: A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX) |
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| Active, not recruiting | N/A | 250 | US, RoW | Route 92 Medical Reperfusion System | Route 92 Medical, Inc. | Acute Ischemic Stroke | 06/24 | 06/24 | | |
| Recruiting | N/A | 168 | Europe, US | Tigertriever 13 | Rapid Medical | Ischemic Stroke, Neovascularization | 08/24 | 08/24 | | |
STERLING, NCT03642639: A Study to Look at Performance of MICRUSFRAME and GALAXY Coils for the Treatment of Intracranial Aneurysms |
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| Recruiting | N/A | 850 | Europe, US | MICRUSFRAME and GALAXY coils | Cerenovus, Part of DePuy Synthes Products, Inc. | Aneurysms | 12/25 | 06/26 | | |
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial |
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| Recruiting | N/A | 2480 | Europe, Canada, US, RoW | Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS | Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS) | Carotid Stenosis | 02/26 | 02/26 | | |
| Recruiting | N/A | 40000 | Europe, Canada, Japan, US, RoW | Stroke/Thrombectomy/Aneurysm-specific surgical procedures | Medical University of South Carolina | Stroke, Thromboses, Intracranial, Aneurysm, Brain | 01/55 | 01/55 | | |
| Zaidat, Sam |
| Completed | N/A | 90 | US | Thermogard XP3, Recanalization only | ZOLL Circulation, Inc., USA | Ischemic Stroke | 05/24 | 05/24 | | |
| Recruiting | N/A | 225 | Europe, US | Millipede System | Perfuze | Acute Ischemic Stroke | 07/25 | 10/25 | | |
| Singer, Justin |
| Recruiting | N/A | 168 | Europe, US | Tigertriever 13 | Rapid Medical | Ischemic Stroke, Neovascularization | 08/24 | 08/24 | | |
NCT04129125: The Imperative Trial: Treatment of Acute Ischemic Stroke With the Zoom Reperfusion System |
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| Recruiting | N/A | 262 | US | Zoom Reperfusion System | Imperative Care, Inc. | Ischemic Stroke, Acute Stroke | 07/24 | 08/24 | | |
EMBOLISE, NCT04402632: Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma |
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| Recruiting | N/A | 600 | US | Surgical Management, Surgical Management + Treatment, No Treatment, Treatment | Medtronic Neurovascular Clinical Affairs | Subdural Hematoma | 10/24 | 03/25 | | |
| Recruiting | N/A | 150 | US | Citadel Embolization Device | Stryker Neurovascular | Unruptured Wide-neck Aneurysms | 06/26 | 03/27 | | |
| Recruiting | N/A | 500 | US | Aurora Surgiscope System | Integra LifeSciences Corporation, Icahn School of Medicine at Mount Sinai, Oculus Imaging LLC | Supratentorial Hemorrhage | 10/28 | 10/29 | | |
| Hickam, Michelle |
| Active, not recruiting | N/A | 1720 | Europe, Canada, US | Microport Firehawk stent, MicroPort Firehawk rapamycin target eluting stent, 2nd generation DES (XIENCE family, Promus family, Resolute/Onyx family/Endeavor, and Orsiro stent) | Shanghai MicroPort Medical (Group) Co., Ltd. | Coronary Artery Disease | 06/24 | 06/27 | | |
| Recruiting | N/A | 1500 | US | Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, CCM Group (CCM ON), OPTIMIZER™ Smart Mini System, Sham Group (CCM OFF) | Impulse Dynamics | Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Moderately Reduced Ejection Fraction, Diastolic Heart Failure | 02/25 | 02/26 | | |
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy |
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| Recruiting | N/A | 620 | US | OPTIMIZER Smart System | Impulse Dynamics | Heart Failure | 03/26 | 03/26 | | |
| Khaldy, Ahmad |
| Recruiting | N/A | 168 | Europe, US | Tigertriever 13 | Rapid Medical | Ischemic Stroke, Neovascularization | 08/24 | 08/24 | | |
| Lin, Eigine |
| Recruiting | N/A | 168 | Europe, US | Tigertriever 13 | Rapid Medical | Ischemic Stroke, Neovascularization | 08/24 | 08/24 | | |
| Sopko, Anthony |
| Completed | N/A | 90 | US | Thermogard XP3, Recanalization only | ZOLL Circulation, Inc., USA | Ischemic Stroke | 05/24 | 05/24 | | |
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial |
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| Recruiting | N/A | 2480 | Europe, Canada, US, RoW | Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS | Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS) | Carotid Stenosis | 02/26 | 02/26 | | |
| White, Ronda |
| Recruiting | N/A | 168 | Europe, US | Tigertriever 13 | Rapid Medical | Ischemic Stroke, Neovascularization | 08/24 | 08/24 | | |
