| Morgenthaler, Timothy I |
NCT04688125: Evaluation of An Optical Measurement Algorithm Combined With Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy |
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| Recruiting | N/A | 264 | US | | Mayo Clinic | Sleep Apnea, Obstructive, Obesity Hypoventilation Syndrome (OHS), Sleep Apnea Syndromes | 12/24 | 12/24 | | |
NCT06381115: App-Based Optimization of Long-Term CPAP Adherence and Quality of Life |
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| Not yet recruiting | N/A | 40 | US | SleepWell24 Application | Mayo Clinic, Arizona State University (ASU) | Obstructive Sleep Apnea | 11/25 | 11/25 | | |
| Recruiting | N/A | 500 | Europe, US | remede System | Respicardia, Inc. | Central Sleep Apnea | 06/27 | 06/32 | | |
| Crouser, Elliott D |
| Recruiting | 1/2 | 80 | US | Citicoline, Somazina, CDP-choline, Saline/Placebo, Normal saline solution | Ohio State University | COVID-19 | 05/25 | 05/26 | | |
NCT05304728: Sepsis Clinical Decision Support [CDS] Master Enrollment Study Protocol |
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| Enrolling by invitation | N/A | 40000 | US | | Beckman Coulter, Inc., Biomedical Advanced Research and Development Authority | Severe Sepsis, Severe Sepsis Without Septic Shock | 03/25 | 12/26 | | |
| Uribe, Alberto A |
NCT04781387: Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile Infection |
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| Active, not recruiting | 2 | 108 | Canada, US | CRS3123, Active Comparator | Crestone, Inc, National Institute of Allergy and Infectious Diseases (NIAID) | Clostridioides Difficile Infection | 02/24 | 04/24 | | |
NCT03512223: Intravenous and Perineural Dexamethasone for Brachial Plexus Block in Hand Surgery |
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| Completed | 1 | 108 | US | Dexamethasone | Ohio State University | Hand Surgery | 10/24 | 10/24 | | |
NCT03498261: A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty |
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| Active, not recruiting | 1 | 50 | US | Gabapentin, Neurotin, Placebos | Ohio State University | Pain, Postoperative, Opioid Use | 07/24 | 12/24 | | |
NCT06231342: Endotracheal Tube (ETT) 180: Stylet-loaded Endotracheal Tube Rotation Before Insertion |
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| Recruiting | N/A | 357 | US | Direct Laryngoscope (DL), Video laryngoscope (VL), Endotracheal Tube (ETT) 180 | Ohio State University | Anesthesia, Endotracheal | 05/27 | 05/27 | | |
NCT06245005: Preoperative Cognitive Reserve in Older Surgical Patients: A Feasibility Study |
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| Recruiting | N/A | 80 | US | Brain exercise gameplay on a portable electronic device | Ohio State University | Cognitive Decline | 09/25 | 09/25 | | |
| Recruiting | N/A | 84 | US | Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine, Pecto-intercostal Fascial Block with normal saline | Ohio State University | Autonomic Nerve Block | 12/26 | 01/27 | | |
NCT06236126: SKIN WHEAL - Subcutaneous or Intradermal Lidocaine in Epidural for Laboring Pain. |
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| Recruiting | N/A | 50 | US | 1% Lidocaine Injection | Ohio State University | Analgesia, Obstetrical | 11/25 | 11/26 | | |
NCT05804175: Advanced Prediction of Respiratory Depression Episode With the Linshom Continuous Predictive Respiratory Sensor |
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| Recruiting | N/A | 600 | US | Linshom Continuous Predictive Respiratory Monitoring, Pulse Oximetry, Capnography | Linshom Medical, Inc., National Heart, Lung, and Blood Institute (NHLBI), Ohio State University | Post Surgical Respiratory Failure, Respiratory Complication | 09/25 | 09/25 | | |
NCT04934995: Arm and Ankle Blood Pressure Cuffs During C-Section |
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| Completed | N/A | 100 | US | Blood Pressure Cuff | Ohio State University | Supine Hypotensive Syndrome, Cesarean Section Complications, Anesthesia Complication | 10/24 | 10/24 | | |
NCT06370338: Cardiothoracic Critical Care as Subspecialty and Its Core Competencies |
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| Recruiting | N/A | 68 | US | Delphi Questionnaire | Ohio State University | Consensus Development | 04/25 | 04/25 | | |
| Recruiting | N/A | 497 | US | Spinal Cord Stimulator (SCS) | Nevro Corp | Diabetic Neuropathy, Painful | 10/27 | 10/28 | | |
NCT05344417: Low Pressure Pneumoperitoneum and Postoperative Ileus |
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| Not yet recruiting | N/A | 125 | US | Pneumoperitoneum Pressure, Neuromuscular blockade, Pneumoperitoneum insufflation device, Neuromuscular blockade reversal | Ohio State University | Postoperative Ileus, Gastrointestinal Dysfunction | 12/26 | 07/27 | | |
| Krishna, Vibhor |
| Completed | N/A | 456 | US | No intervention, Single Arm Group | Ohio State University | Parkinson Disease, Dystonia, Tremors, Obsessive Compulsive Disorder, Depression | 08/21 | 10/21 | | |
NCT03560622: Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy |
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| Active, not recruiting | N/A | 30 | US | multi-modality neuroimaging | Vibhor Krishna, National Institutes of Health (NIH), Focused Ultrasound Foundation | Essential Tremor | 12/21 | 12/21 | | |
LIBERATE, NCT05383872: Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects with GlioBlastoma Brain Tumors |
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| Recruiting | N/A | 57 | Canada, US | Focused Ultrasound (Exablate Model 4000) | InSightec | Glioblastoma, Glioma, Liquid Biopsy | 12/24 | 03/25 | | |
NCT06331052: 3-D Tractography FUS Ablation for Essential Tremor |
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| Recruiting | N/A | 24 | US | MR-guided Focused Ultrasound Ablation, 3-D Tractography | University of North Carolina, Chapel Hill, Texas Tech University Health Sciences Center, El Paso, University of Pittsburgh, National Institute of Neurological Disorders and Stroke (NINDS) | Essential Tremor | 02/28 | 02/28 | | |
NCT03417297: A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy |
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| Recruiting | N/A | 10 | US | High Intensity Focused Ultrasound, ExAblate Model 4000 Type-1 Focused Ultrasound | University of North Carolina, Chapel Hill, Focused Ultrasound Foundation | Partial Seizures With Secondary Generalization | 05/25 | 05/25 | | |
| Augostini, Ralph |
| Recruiting | N/A | 80 | US | Satera GSN Ablation, Sham Control | Axon Therapies, Inc. | Heart Failure With Preserved Ejection Fraction | 04/22 | 03/23 | | |
NCT03444337: High-resolution MRI of Atrial Fibrillation Patients Prior to Focal Impulse and Rotor Modulation (FIRM) Ablation |
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| Recruiting | N/A | 20 | US | Catheter Ablation | Ohio State University | Atrial Fibrillation | 12/24 | 12/24 | | |
| Recruiting | N/A | 30 | US | Transvenous nerve stimulation | Respicardia, Inc. | Sleep Apnea Syndromes | 03/25 | 06/25 | | |
| Recruiting | N/A | 500 | Europe, US | remede System | Respicardia, Inc. | Central Sleep Apnea | 06/27 | 06/32 | | |
| Woodburn, Erin |
CELLO, NCT04877457: Ocrelizumab for Preventing Clinical Multiple Sclerosis in Individuals With Radiologically Isolated Disease. |
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| Terminated | 4 | 3 | US | Ocrelizumab, Placebo | Yale University, Genentech, Inc. | Radiologically Isolated Syndrome, Multiple Sclerosis | 06/23 | 06/23 | | |
| Recruiting | N/A | 152 | US | Active MeRT Treatment, rTMS Active Stimulator, Sham MeRT Treatment, rTMS Sham Stimulator | Wave Neuroscience, Texas A&M University, GilpinPhillips BIOMED, LLC, Peachtree BioResearch Solutions | PostTraumatic Stress Disorder, Traumatic Brain Injury, Postconcussive Symptoms | 07/24 | 09/24 | | |
NCT03417297: A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy |
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| Recruiting | N/A | 10 | US | High Intensity Focused Ultrasound, ExAblate Model 4000 Type-1 Focused Ultrasound | University of North Carolina, Chapel Hill, Focused Ultrasound Foundation | Partial Seizures With Secondary Generalization | 05/25 | 05/25 | | |
| Brougher, Sarah |
| Recruiting | N/A | 30 | US | Transvenous nerve stimulation | Respicardia, Inc. | Sleep Apnea Syndromes | 03/25 | 06/25 | | |
| Recruiting | N/A | 500 | Europe, US | remede System | Respicardia, Inc. | Central Sleep Apnea | 06/27 | 06/32 | | |
| Sevensma, Matthew |
| Recruiting | N/A | 500 | Europe, US | remede System | Respicardia, Inc. | Central Sleep Apnea | 06/27 | 06/32 | | |
| Karl, Cindy |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | N/A | 600 | US | Pressure applied during RARP | Metro Health, Michigan | Prostate Cancer | 06/24 | 06/25 | | |
| Recruiting | N/A | 1000 | US | MicroVention Mechanical Thrombectomy Devices as first-line treatment | Microvention-Terumo, Inc. | Acute Ischemic Stroke, Vessel Occlusion, Stroke, Ischemic | 12/25 | 12/25 | | |
| Recruiting | N/A | 500 | Europe, US | remede System | Respicardia, Inc. | Central Sleep Apnea | 06/27 | 06/32 | | |
| Karow, Sarah |
BREATHE-easy, NCT05416437: Breathlessness Relieved by Employing Medical Air to be Titrated by Hospitalized Patients to Improve Inpatient Experience |
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| Recruiting | N/A | 80 | US | PneumoCool, Current supportive measures that are used in the hospital for standard of care | Ohio State University | Dyspnea | 01/24 | 06/24 | | |
NCT05923853: Electronic Optimization of Inspired Oxygen During Mechanical Ventilation, a Pragmatic Randomized Trial (OPTI-Oxygen) |
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| Recruiting | N/A | 936 | US | FiO2 titration using electronic alert system | Ohio State University, National Heart, Lung, and Blood Institute (NHLBI) | Hyperoxia | 08/25 | 05/26 | | |
| Adjei-Poku, Yaw |
NCT06292013: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a) |
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| Recruiting | 3 | 12500 | Europe, Canada, Japan, US, RoW | Lepodisiran Sodium, LY3819469, Placebo | Eli Lilly and Company | Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a) | 03/29 | 03/29 | | |
ACHIEVE-4, NCT05803421: A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk |
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| Active, not recruiting | 3 | 2749 | Europe, US, RoW | Orforglipron, LY3502970, Insulin Glargine | Eli Lilly and Company | Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease | 09/25 | 01/26 | | |
ATTAIN-2, NCT05872620: A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes |
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| Active, not recruiting | 3 | 1500 | Europe, US, RoW | Orforglipron, LY3502970, Placebo | Eli Lilly and Company | Obesity, Overweight, Type 2 Diabetes | 08/25 | 08/25 | | |
| Active, not recruiting | 3 | 15374 | Europe, Canada, Japan, US, RoW | Tirzepatide, LY3298176, Placebo | Eli Lilly and Company | Obesity, Overweight | 10/27 | 10/27 | | |
| Recruiting | N/A | 500 | Europe, US | remede System | Respicardia, Inc. | Central Sleep Apnea | 06/27 | 06/32 | | |
| Nascak, Sam |
| Recruiting | N/A | 40 | US | Fermented Food Diet | Mayo Clinic | Critical Illness, COVID-19, PICS, Cognitive Impairment, Mental Health Impairment, Weakness, Muscle, Dysbiosis | 04/25 | 04/25 | | |
| Recruiting | N/A | 500 | Europe, US | remede System | Respicardia, Inc. | Central Sleep Apnea | 06/27 | 06/32 | | |
