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13 Active 4 Inactive 17 All	Not yet recruiting Recruiting Enrolling by invitation Active, not recruiting Available No longer recruiting	Industry lead sponsor Industry collaborator Coop Other	US Canada Japan Europe RoW	N/A 1 2 3 4	Highlight changes:- Show only changed items Enrollment:

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6 Trials

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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Smith, Amanda
REFOCUS-ALZ, NCT05026177: Simufilam 50 mg or 100 mg for Mild-to-Moderate Alzheimer's Disease	Terminated	3	1125	Canada, US, RoW	Simufilam, PTI-125, Placebo	Cassava Sciences, Inc., Premier Research Group plc	Alzheimer Disease	12/24	12/24
ENVISION, NCT05310071 / 2022-001671-14: A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease	Terminated	3	1027	Europe, Canada, Japan, US, RoW	Aducanumab, BIIB037, Aducanumab-avwa, Aduhelm, Placebo	Biogen, Biogen Idec Research Limited	Alzheimer's Disease	08/24	08/24
Spectra, NCT05393284: Phase 2 Study to Evaluate the Safety and Efficacy of OPL-0401 in Patients With Diabetic Retinopathy	Active, not recruiting	2	114	US	OPL-0401 Dose 1, Placebo	Valo Health, Inc.	Non-proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy	08/24	08/24
MAGIC, NCT05681884: Safety and Efficacy of Faricimab in Patients With NPDR	Active, not recruiting	2	179	US	Faricimab	Greater Houston Retina Research, Genentech, Inc.	Non-Proliferative Diabetic Retinopathy	03/26	04/26
NCT05715346: LEV102 Topical Gel in Acquired Blepharoptosis	Completed	1/2	33	US	LEV102 1.0%, LEV102 2.0%, Vehicle	Levation Pharma, Ltd.	Acquired Blepharoptosis	06/23	06/23
i-GAIN, NCT05797896: Investigating Geographic Atrophy Insights () Natural History Study	Recruiting	N/A	250	Europe, US		Complement Therapeutics	Dry Age-related Macular Degeneration, Geographic Atrophy, Retinal Disease, Macular Degeneration, Macular Atrophy, Retinal Degeneration, Eye Diseases	12/26	12/26
Raj, Balebail A
No trials found
Janavs, Juris
No trials found
Flynn, Myrna DeJesus
No trials found
Rodrigo, Kelly
No trials found
Ettelson, David
No trials found
Major, Beth
No trials found