University Hospital Kralovske Vinohrady
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 5 Trials 
22 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Motovska, Zuzana
DAPT-SHOCK-AMI, NCT03551964: Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction

Active, not recruiting
4
605
Europe, RoW
Cangrelor, intravenous P2Y12 inhibitor, Ticagrelor, oral P2Y12 inhibitor
Faculty Hospital Kralovske Vinohrady, Charles University, Czech Republic
Acute Myocardial Infarction, Cardiogenic Shock
02/24
01/25
Cerna, Olga
ROP-ET, NCT06514807: A Study to Evaluate the Efficacy and Safety of Ropeginterferon Alfa-2b in Essential Thrombocythaemia Patients

Active, not recruiting
3
117
Europe, RoW
Ropeginterferon alfa-2b (BESREMi®)
AOP Orphan Pharmaceuticals AG
Essential Thrombocythaemia
03/28
03/28
KER050-MD-201, NCT04419649 / 2021-001838-19: A Study of KER-050 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

Hourglass Dec 2024 - Dec 2024 : Additional data for very low, low, or intermediate risk myelodysplastic syndrome
Hourglass Jul 2023 - Dec 2023 : Enrollment completion of transfusion dependent cohorts of trial for low, or intermediate risk MDS
Recruiting
2
140
Europe, US, RoW
KER-050
Keros Therapeutics, Inc., Keros Therapeutics, Inc.
Myelodysplastic Syndromes, Cytopenia
06/25
11/25
HALF, NCT04147533: Efficacy and Safety of TKIs' Withdrawal After a Two-step Dose Reduction in Patients with Chronic Myeloid Leukemia

Active, not recruiting
2
150
RoW
Imatinib withdrawal, Glivec withdrawal, Dasatinib, Sprycel withdrawal, Nilotinib, Tasigna withdrawal
Masaryk University
Chronic Myeloid Leukemia, Chronic Phase, Withdrawal;Drug
06/26
06/26
Mocikova, Heidi
ECHELON-3, NCT04404283 / 2020-002686-33: Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

Hourglass Jan 2023 - Dec 2023 : From:ECHELON-3 trial in combination with brentuximab vedotin and rituximab for r/r DLBCL
Active, not recruiting
3
240
Europe, Canada, US, RoW
Brentuximab vedotin, Rituximab, Lenalidomide, Placebo
Seagen Inc.
Diffuse Large B-cell Lymphoma
05/25
04/27
BRUIN CLL-322, NCT04965493 / 2021-000043-49: A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Recruiting
3
600
Europe, Canada, Japan, US, RoW
Pirtobrutinib, LOXO-305, LY3527727, Venetoclax, Venclexta, Venclyxto, Rituximab, Rituxan, MabThera, Truxima, Riabni, Ruxience
Loxo Oncology, Inc., Eli Lilly and Company
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
04/26
01/27
SGN35-032, NCT04569032 / 2020-002336-74: A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Active, not recruiting
2
82
Europe, US, RoW
brentuximab vedotin, ADCETRIS, cyclophosphamide, doxorubicin, prednisone
Seagen Inc.
Peripheral T-cell Lymphoma
05/24
12/25
CLSGMCLPOLA, NCT04913103: Study of PV in Combination With Bendamustine and Rituximab for Patients With R/R MCL

Not yet recruiting
2
21
RoW
Polatuzumab vedotin, Polivy, Bendamustine Hydrochloride, Bendamustine Accord, Bendamustine Glenmark, Bendamustine KABI, Rituximab, Mabthera, Rixathon, Truxima
Czech Lymphoma Study Group
Lymphoma, Mantle-Cell
08/26
08/27
NU22-03-00182, NCT06263530: Prognostic Significance of ctDNA in HL

Recruiting
N/A
500
RoW
Interni hematologicka klinika FNKV, Charles University, Czech Republic, General University Hospital, Prague, University Hospital Olomouc, University Hospital Hradec Kralove, University Hospital, Motol
Prognostic Cancer Model
12/23
12/27
Duska, Frantisek
PPE-TEAM, NCT04742426: Personal Protective Equipment Affect Team Performance During Medical Emergencies

Not yet recruiting
N/A
22
NA
WHO recommended PPE, Super-safe setup
Roman Sýkora
Safety Issues, Communication, Cardiopulmonary Arrest
08/21
09/21
NCT06147674: Evaluation of VQm PHM on Pulmonary Health Parameters for ICU

Not yet recruiting
N/A
150
Europe, US, RoW
VQm Pulmonary Health Monitor™
Rostrum Medical Innovations Inc., Medical Initiatives
Ventilators, Mechanical, Stroke, COPD, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Pneumonia
01/25
03/25
FEBATRICE, NCT05430269: Faecal Bacteriotherapy for Postantibiotic Diarrhoea in Critically Ill Patients

Recruiting
N/A
36
RoW
Faecal bacteriotherapy (FBT), standard-of-care protocolised treatment of postantibiotic diarhea
Charles University, Czech Republic, Faculty Hospital Kralovske Vinohrady, Donatio Intensivistam Endowment Fund
Diarrhea Caused by Drug, Clostridium Difficile Infections
12/24
07/25
POS-VAP, NCT05719259: Perpetual Observational Study - Ventilator Associated Pneumonia

Recruiting
N/A
20000
Europe, RoW
VAP
European Clinical Research Alliance for Infectious Diseases (ECRAID), Centre Hospitalier Universitaire Dupuytren de Limoges (CHUL), Université de Genève (UNIGE), University Medical Center Utrecht (UMCU)
Ventilator Associated Pneumonia
12/25
03/26
HONEST-PREPS, NCT05060718: HOspital NEtwork STudy - Preparation for a Randomized Evaluation of Anti-Pneumonia Strategies

Completed
N/A
2165
Europe, RoW
UMC Utrecht, Universiteit Antwerpen, University Hospital, Geneva
Hospital-acquired Pneumonia, Ventilator Associated Pneumonia
05/22
01/23
Malek, Jiri
NCT05288374: Celecoxib in Postoperative Analgesia for Radius Fracture Surgery

Completed
4
42
RoW
Celecoxib 100 mg, Celebrex 100 mg, Placebo, Placebo pill
Charles University, Czech Republic, Faculty Hospital Kralovske Vinohrady
Pain, Postoperative
11/23
12/23
NCT05303805: Topical Sevoflurane for Treatment of Chronic Leg Ulcers

Recruiting
4
50
RoW
Sevoflurane, Sevorane, Cyteal
Charles University, Czech Republic, Faculty Hospital Kralovske Vinohrady
Leg Ulcer
04/26
01/27
Kurzova, Alice
NCT05288374: Celecoxib in Postoperative Analgesia for Radius Fracture Surgery

Completed
4
42
RoW
Celecoxib 100 mg, Celebrex 100 mg, Placebo, Placebo pill
Charles University, Czech Republic, Faculty Hospital Kralovske Vinohrady
Pain, Postoperative
11/23
12/23
NCT05303805: Topical Sevoflurane for Treatment of Chronic Leg Ulcers

Recruiting
4
50
RoW
Sevoflurane, Sevorane, Cyteal
Charles University, Czech Republic, Faculty Hospital Kralovske Vinohrady
Leg Ulcer
04/26
01/27
Rob, Lukas
FLORA-4, NCT04498117 / 2020-002270-26: Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery

Active, not recruiting
3
615
Europe, Canada, US, RoW
Oregovomab, MAb-B43.13, Paclitaxel, Taxol, Carboplatin, Paraplatin, Placebo
CanariaBio Inc., Gynecologic Oncology Group, Iqvia Pty Ltd
Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma, Fallopian Tube Neoplasms, Fallopian Tube Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Peritoneal Cancer, Peritoneal Carcinoma, Peritoneal Neoplasms
09/25
08/27
Curila, Karol
NCT04908033: Ultra-high-frequency ECG for Prediction of Left Ventricular Remodeling

Recruiting
N/A
360
RoW
pacemaker implantation
Faculty Hospital Kralovske Vinohrady, St. Anne's University Hospital Brno, Czech Republic, Regional Hospital Liberec
RV Pacing, Negative Remodeling, Dyssynchrony, UHF-ECG, Physiological Pacing
05/24
05/25
ABACUS, NCT06207383: Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation with Conduction System Pacing in Heart Failure

Recruiting
N/A
220
Europe
Conduction system pacing, Atrioventricular nodal ablation, Atrial fibrillation ablation
University Hospital, Geneva, Swiss National Science Foundation
Atrial Fibrillation, Persistent, Heart Failure
06/28
12/28
LEAP-pilot, NCT04595487: LVSP vs RVP in Patients With AV Conduction Disorders

Recruiting
N/A
470
Europe, RoW
Left ventricular septal pacing, Right ventricular pacing
Maastricht University, ZonMw: The Netherlands Organisation for Health Research and Development, Medtronic
Cardiac Pacing, Pacing-Induced Cardiomyopathy, Conduction System Pacing, Left Ventricular Septal Pacing, Atrioventricular Block
05/25
05/25

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