| Walter, Peter |
| Active, not recruiting | N/A | 38 | Europe | PRIMA Bionic Vision System | Science Corporation | Geographic Atrophy | 02/24 | 02/28 | | |
| Recruiting | N/A | 2000 | Europe | | University Hospital Muenster, University Medicine Greifswald, University Medical Center Mainz, University Hospital, Aachen, Klinikum Chemnitz gGmbH, Technische Universität Dresden, University of Leipzig, University Hospital Tuebingen, Deutsche Ophthalmologische Gesellschaft e.V., Pro Retina Deutschland e.V. | Intravitreal Injections | 02/28 | 02/28 | | |
| Recruiting | N/A | 3000 | Europe, RoW | Registry of preterm born infants with treatment-requiring ROP | University Medicine Greifswald | Retinopathy of Prematurity | 08/38 | 08/39 | | |
| Trautwein, Christian |
NCT03866187 / 2017-001452-55: Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection |
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| Terminated | 1/2 | 135 | Europe, RoW | ChAd155-hIi-HBV low dose formulation, ChAd155-hIi-HBV high dose formulation, HBc-HBs/AS01B-4 low dose formulation, HBc-HBs/AS01B-4 high dose formulation, MVA-HBV low dose formulation, MVA-HBV high dose formulation, Placebo | GlaxoSmithKline, GlaxoSmithKline Biologicals | Hepatitis B, Chronic | 10/24 | 10/24 | | |
ADLH, NCT03897218: Dietary Modulation of Intestinal Microbiota as Trigger of Liver Health: Role of Bile Acids - "A Diet for Liver Health" |
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| Completed | N/A | 84 | Europe | oatmeal flakes with prebiotic food supplements, millet flakes | RWTH Aachen University | NASH - Nonalcoholic Steatohepatitis | 04/22 | 04/22 | | |
| Recruiting | N/A | 1200 | Europe | UDCA, ursodeoxycholic acid, Ocaliva, obeticholic acid | University of Leipzig, RWTH Aachen University, Zentrum für Klinische Studien Leipzig, Intercept Pharma Europe Limited (IPEL), Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), University Hospital Erlangen, Medical care center for Gastroenterology, Berlin, Institute for Interdisciplinary Medicine, Hamburg, Leberhilfe Projekt gUG, Cologne, Hannover Medical School | PBC, Primary Biliary Cholangitis | 03/24 | 03/24 | | |
| Recruiting | N/A | 10000 | Europe | | Newcastle University, Newcastle-upon-Tyne Hospitals NHS Trust, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Institute of Cardiometabolism and Nutrition, France, University of Cambridge, Örebro University, Sweden, University of Bern, University of Oxford, University of Turin, Italy, University of Angers, University Hospital, Antwerp, Linkoeping University, University of Helsinki, UMC Utrecht, National and Kapodistrian University of Athens, University of Lisbon, University of Milan, University of Palermo, Catholic University of the Sacred Heart, Wuerzburg University Hospital, RWTH Aachen University, University of Nottingham, Medical University of Vienna, University of Birmingham, University of Florence, Assistance Publique - Hôpitaux de Paris, University Medical Center Mainz | NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Liver, Steatosis of Liver, Hepatocellular Carcinoma, Cardiovascular Diseases, Type 2 Diabetes, Dyslipidaemia, Hypertension, Obesity, Other Associated Comorbidities | 12/30 | 12/30 | | |
| Dreher, Michael |
NCT04144296: Mathematical Arterialisation of Capillary Blood for Blood Gas Analysis in Critical Ill Patients |
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| Recruiting | N/A | 70 | Europe | Study procedure | RWTH Aachen University, OBI Medical | Lung Diseases | 10/21 | 11/21 | | |
| Active, not recruiting | N/A | 169 | Europe | Non-invasive ventilation | ResMed, CRI-The Clinical Research Institute GmbH | Chronic Obstructive Pulmonary Disease | 12/24 | 06/25 | | |
NCT05582642: Respiratory Muscles After Inspiratory Muscle Training After COVID-19 |
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| Completed | N/A | 18 | Europe | Inspiratory Muscle Training (IMT) | RWTH Aachen University, Philipps University Marburg Medical Center | COVID-19, Diaphragm Injury | 04/23 | 04/23 | | |
| Completed | N/A | 50 | Europe | Comprehensive assessment of respiratory muscle function. | RWTH Aachen University | Covid19, Diaphragm Injury | 07/23 | 11/23 | | |
| Recruiting | N/A | 80 | Europe | Assessments of the sympathetic nerve activity axis, OSA severity, Determination of PH and right HF severity, Comprehensive lung function and inspiratory muscle function testing., Assessment of systemic inflammation | RWTH Aachen University | COPD, Sympathetic Nervous System Diseases, Catecholamine; Overproduction | 04/24 | 08/24 | | |
| Recruiting | N/A | 15 | Europe | Respiratory Muscle Testing | RWTH Aachen University | Diaphragm Issues, Mechanical Ventilation Complication, Respiratory Failure, Intensive Care (ICU) Myopathy | 12/23 | 12/23 | | |
| Not yet recruiting | N/A | 25 | Europe | Comprehensive assessment of respiratory muscle function. | RWTH Aachen University | Covid19, Diaphragm Injury | 12/24 | 12/24 | | |
| Recruiting | N/A | 800 | Europe | Diaphragm Ultrasound, Intercostal Muscle Ultrasound, Borg scale, MRC Breathlessness Scale, Respiratory Questionaire, GINA classification of Asthma, Measurement of respiratory mouth pressure, SNIP, 6-minute walking distance, 60 seconds sit-to-stand test, Electromyography, Lung Function, CAT-Questionnaire, European Society of Cardiology (ESC)/ European Respiratory Society (ERS) risk group | RWTH Aachen University | Dyspnea; Asthmatic, COPD, Fibrosis, Pulmonary Hypertension, Asthma, Dyspnea | 06/25 | 06/25 | | |
| Recruiting | N/A | 30 | Europe | | RWTH Aachen University, ResMed | Asthma | | | | |
| Frodl, Thomas |
CARE, NCT05813080: Computer-assisted Risk Evaluation in the Early Detection of Psychotic Disorders |
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| Recruiting | N/A | 436 | Europe | "pronia.ai" medical device for high risk psychosis prognosis, Treatment-as-usual (TAU) | Heinrich-Heine University, Duesseldorf | Psychotic Disorders, Prevention | 12/24 | 03/25 | | |
| Not yet recruiting | N/A | 140 | Europe | maintenance electroconvulsive therapy (mECT) | Central Institute of Mental Health, Mannheim | Schizophrenia, Treatment Resistant Schizophrenia | 07/27 | 07/28 | | |
| Yazdi, Amir |
| Recruiting | 3 | 183 | Europe | InfectoScab 5 % Creme, Permethrin 10 % Creme, Driponin 3 mg Tabletten | Infectopharm Arzneimittel GmbH, Winicker Norimed GmbH | Scabies | 12/22 | 08/23 | | |
| Recruiting | 2/3 | 474 | Europe, Canada, Japan, US, RoW | Litifilimab, BIIB059, Placebo | Biogen, Biogen Idec Research Limited | Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus | 10/26 | 12/27 | | |
| Tacke, Frank |
NCT06165341: Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis) |
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| Recruiting | 3 | 50 | Europe, Canada, US | Fazirsiran Injection, TAK-999, ARO-AAT, ADS-001, Placebo | Takeda | Alpha1-Antitrypsin Deficiency | 08/28 | 08/28 | | |
NCT05677971: Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein |
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| Recruiting | 3 | 160 | Europe, Canada, US, RoW | Fazirsiran Injection, TAK-999, ARO-AAT, ADS-001, Placebo, Sodium chloride | Takeda, Takeda Development Center Americas, Inc. | Alpha1-Antitrypsin Deficiency | 03/27 | 03/29 | | |
CaPture, NCT04767906: Cabozantinib Treatment in a Phase II Study for Patients With Hepatocellular Carcinoma (HCC) Refractory to PD-1 Inhibitors |
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| Recruiting | 2 | 40 | Europe | Cabozantinib | University of Leipzig | Hepatocellular Carcinoma | 06/24 | 12/24 | | |
NCT04662918: Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding |
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| Recruiting | N/A | 3000 | Europe, US, RoW | | Xingshun Qi | GastroIntestinal Bleeding | 12/24 | 12/24 | | |
NCT05239858: International Wilson's Disease Patient Registry (iWilson Registry) |
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| Recruiting | N/A | 500 | Europe, RoW | | Orphalan, Ergomed | Wilson's Disease | 12/27 | 12/27 | | |
