Kim, Ji Hong |
ADAPT, NCT04782375: Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis B |
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| Active, not recruiting | 4 | 140 | RoW | Stop group, discontinue antiviral treatment | Asan Medical Center | Hepatitis B, Chronic | 08/24 | 12/24 | | |
ATTACH, NCT04780204: Effectiveness of Antiviral Treatment in Cirrhotic Patients with Low-level Hepatitis B Virus DNA Levels |
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| Active, not recruiting | 4 | 600 | RoW | Treatment, Tenofovir alafenamide | Asan Medical Center, National Evidence-Based Healthcare Collaborating Agency | Hepatitis B, Chronic | 01/27 | 12/27 | | |
ATTENTION, NCT03753074: Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines |
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| Active, not recruiting | 4 | 780 | RoW | Tenofovir Alafenamide, Vemlidy | Young-Suk Lim, Samsung Medical Center, Kyunghee University Medical Center, Chung-Ang University Hosptial, Chung-Ang University College of Medicine, Seoul National University Hospital, Ulsan University Hospital, Konkuk University Medical Center, Kyungpook National University Hospital, Korea University Guro Hospital, Seoul St. Mary's Hospital, Kaohsiung Medical University, Chang Gung Memorial Hospital, E-DA Hospital, Taitung Mackay Memorial Hospital, National Cheng-Kung University Hospital, Chi Mei Medical Hospital, Chiayi Christian Hospital, St. Martin De Porress Hospital, Dalin Tzu Chi General Hospital, Taichung Veterans General Hospital, China Medical University Hospital, Seoul National University Bundang Hospital | Chronic Hepatitis b | 12/31 | 12/31 | | |
Aladdin, NCT04618640: To Evaluate the Immunogenicity and Safety of DTaP-IPV Vaccine Administered as a Boosting Dose to Healthy Children of 4-6 Years |
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| Recruiting | 3 | 249 | RoW | DTaP-IPV combination vaccine | Boryung Biopharma Co., Ltd. | Diphtheria, Tetanus, Pertussis, Poliomyelitis | 12/20 | 07/21 | | |
KONCLUDE, NCT02843191: Consolidation Chemotherapy for Locally Advanced Mid or Low Rectal Cancer After Neoadjuvant Concurrent Chemoradiotherapy |
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| Recruiting | 3 | 358 | RoW | Chemotherapy | Kyung Hee University Hospital at Gangdong, Korean Society of ColoProctology | Rectal Cancer | 11/23 | 07/24 | | |
| Active, not recruiting | 3 | 941 | Europe, Canada, Japan, US, RoW | Bepirovirsen, Placebo | GlaxoSmithKline, GlaxoSmithKline Research & Development Limited | Chronic Hepatitis B, Hepatitis B, Chronic | 11/25 | 05/26 | | |
| Recruiting | 3 | 2140 | Canada, US | Radiation, No Radiation | Canadian Cancer Trials Group, Alliance for Clinical Trials in Oncology, Eastern Cooperative Oncology Group, NRG Oncology, SWOG Cancer Research Network | Breast Cancer | 09/27 | 12/27 | | |
| Recruiting | 3 | 1700 | RoW | Aspirin 100mg, Placebo oral tablet | National Cancer Center, Korea, Incheon St.Mary's Hospital/The Catholic University, Kosin University Gospel Hospital, Pusan National University Hospital, SMG-SNU Boramae Medical Center, Chonnam National University Hospital, Chung-Ang University Hosptial, Chung-Ang University College of Medicine, Chilgok Kyungpook National University, Hallym University Medical Center, Seoul National University Hospital, Asan Medical Center | Aspirin, Gastric Cancer | 12/27 | 12/28 | | |
NAVIGATE, NCT04365868: Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis |
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| Active, not recruiting | 2b | 357 | Europe, Canada, US, RoW | belapectin, GR-MD-02, galactoarabino rhamnogalacturonate, Placebo | Galectin Therapeutics Inc. | Prevention of Esophageal Varices, NASH - Nonalcoholic Steatohepatitis, Cirrhosis | 12/24 | 12/24 | | |
NCT05532124: Part A: In Patients With Chronic Liver Diseases, LAENNEC (Human Placenta Hydrolysate) is to Assess Safety and Tolerability After the Doses of Doses. Part B: Part A, it is to Determine the Optimal Dose by Evaluating Two Capacity and Placebo Groups. |
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| Recruiting | 2 | 49 | RoW | LAENNEC (Human Placenta Hydrolysate), normal saline | Green Cross Wellbeing | Chronic Liver Disease | 03/23 | 06/23 | | |
NCT04505436: Study to Evaluate Efficacy, Safety and Tolerability of HM15211 in Subjects |
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| Recruiting | 2 | 240 | US, RoW | HM15211, Placebo of HM15211 | Hanmi Pharmaceutical Company Limited | NASH - Nonalcoholic Steatohepatitis | 05/25 | 11/25 | | |
| Recruiting | 1 | 6 | RoW | umbilical cord-derived mesenchymal stem cell, CordSTEM-ST | CHABiotech CO., Ltd | Premature Ovarian Insufficiency | 05/25 | 05/25 | | |
| Completed | N/A | 72 | RoW | Head on bed, Head on pillow | Ajou University School of Medicine | Gallbladder Diseases | 12/22 | 12/22 | | |
NCT05212038: An Iliopsoas Plane Block After Total Hip Arthroplasty |
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| Completed | N/A | 56 | RoW | iliopsoas plane block group, sham block group | Gangnam Severance Hospital | Total Hip Arthroplasty | 01/23 | 01/23 | | |
NCT04414956: Combining Biomarkers (AFP, AFP-L3, and PIVKA-II) and Image Tools for Early Detection of Hepatocellular Carcinoma |
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| Recruiting | N/A | 1418 | RoW | AFP-L3, Lens culinaris agglutinin-reactive fraction of AFP, AFP, Alpha fetoprotein, PIVKA-II, Protein induced by vitamin K absence or antagonist-II, des-gamma-carboxy prothrombin, Sonography, Ultrasound, US, CT, Computed tomography | Korea University, Korea Unversity Ansan Hospital, Soonchunhyang University Hospital, Korea University Guro Hospital, The Catholic University of Korea, Samsung Medical Center, Asan Medical Center, Korea University Anam Hospital, Keimyung University Dongsan Medical Center, Severance Hospital, Hanyang University, Konkuk University Hospital, Seoul National University Hospital, Inje University, Chung-Ang University Hosptial, Chung-Ang University College of Medicine | Liver Cirrhosis, Hepatocellular Carcinoma, Surveillance | 06/23 | 02/26 | | |
NCT05322902: Remimazolam Total Intravenous Anesthesia Under Analgesia Nociception Index-guidance |
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| Completed | N/A | 84 | RoW | remimazolam group, propofol group | Gangnam Severance Hospital | Knee Osteoarthritis, Total Knee Arthroplasty, Remimazolam | 07/23 | 07/23 | | |
NCT03824522: Post Marketing Surveillance Study for ADYNOVATE in South Korea |
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| Completed | N/A | 341 | RoW | ADYNOVATE, PEGylated rFVIII | Takeda, Takeda Pharma Korea Co. Ltd. | Hemophilia A | 01/24 | 01/24 | | |
NCT05871424: Transdermal Buprenorphine Patch for Laparoscopic Cholecystectomy |
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| Completed | N/A | 66 | RoW | buprenorphine patch group, placebo group | Gangnam Severance Hospital | Laparoscopic Cholecystectomy | 02/24 | 02/24 | | |
NCT05487001: Perineural Dexamethasone for Continuous Femoral Nerve Block |
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| Completed | N/A | 18 | RoW | dexamethasone group, sham group | Gangnam Severance Hospital | Total Knee Arthroplasty | 01/24 | 01/24 | | |
NCT06446193: To Evaluate the Efficacy and Safety of 'NDTx-01' in Patients With ASD or SCD |
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| Recruiting | N/A | 80 | RoW | NDTx-01, TAU | Neudive Inc. | Autism Spectrum Disorder, Social Communication Disorder | 03/25 | 03/25 | | |
| Recruiting | N/A | 56 | RoW | Arm I (mirogabalin group), Arm II (placebo group) | Gangnam Severance Hospital | Hip Osteoarthritis | 06/25 | 06/25 | | |
| Not yet recruiting | N/A | 40 | US | Natural Compound A (masked essential oil A), Natural Compound B (masked essential oil B) | Stanford University | Healthy | 12/25 | 12/25 | | |
Lee, Jiwon |
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis |
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| Active, not recruiting | 2/3 | 301 | Europe, Japan, US, RoW | HZN-825 BID, Placebo, HZN-825 QD | Amgen, Horizon Therapeutics USA, Inc | Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic | 09/25 | 09/25 | | |
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NCT05654311: Performance of EEG During Emergence Agitation in Nasal Surgery. |
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| Recruiting | N/A | 55 | RoW | Nasal surgery | Gangnam Severance Hospital | Nasal Surgery | 10/24 | 10/24 | | |
NCT05669443: Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy |
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| Recruiting | N/A | 42 | RoW | conventional PEEP, optimized PEEP | Gangnam Severance Hospital | Prostate Cancer | 11/24 | 11/24 | | |
KOSMOS-II, NCT05525858: KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II |
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| Recruiting | N/A | 1000 | RoW | Alectinib, Alecensa, Atezolizumab, Tecentriq, Erlotinib, Tarceva, Trastuzumab + Pertuzumab, Herceptin + Perjeta, Trastuzumab emtansine, Kadcyla, Vemurafenib, Zelboraf, Bevacizumab + Erlotinib, Avastin + Tarceva, Entrectinib, Rozlytrek, Pralsetinib, Gavreto | Seoul National University Bundang Hospital, Korean Cancer Study Group, Roche Pharma AG | Solid Tumor, Advanced Solid Tumor, Metastatic Cancer | 09/26 | 03/27 | | |
NCT04174157: Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA) |
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| Recruiting | N/A | 500 | Europe, Japan, US, RoW | Prospective observational registry, Zolgensma | Novartis Pharmaceuticals, United BioSource, LLC | Spinal Muscular Atrophy (SMA) | 06/38 | 06/38 | | |
Han, Dong Soo |
NCT04968054: Comparison of IONM Between Remimazolam and Propofol |
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| Completed | N/A | 66 | RoW | Arm I (Propofol), Arm II (Remimazolam) | Gangnam Severance Hospital | Ossification Posterior Longitudinal Ligament, Cervical Spondylotic Myelopathy | 05/23 | 05/23 | | |
NCT04994704: Comparison of Postoperative QoR-15 Scores Between Propofol and Remimazolam |
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| Completed | N/A | 73 | RoW | Propfol group, Remimazolam group | Gangnam Severance Hospital | Patients Undergoing Spine Surgery | 07/23 | 07/23 | | |
NCT05936671: EEG and ANI Guided Anesthesia and Quality of Recovery |
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| Recruiting | N/A | 126 | RoW | EEG-and-ANI-guided anesthesia, standard anesthesia, Sevoflurane and remifentanil, EEG and ANI | Gangnam Severance Hospital | Laparoscopic Gynecological Surgery | 06/25 | 06/25 | | |
Lee, Ji Hyun |
NCT06113198 / 2023-000764-58: A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of Age |
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| Recruiting | 4 | 50 | RoW | rMenB+OMV NZ | GlaxoSmithKline, GlaxoSmithKline Biologicals SA | Meningitis, Meningococcal | 04/26 | 09/26 | | |
| Active, not recruiting | 3 | 878 | RoW | taxane plus carboplatin, Taxane | Yonsei University | Breast Cancer | 06/25 | 06/25 | | |
NCT05936658: [18F]Florastamin PET/CT Imaging Examination in Patients With Suspected Recurrent or Metastatic Prostate Cancer |
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| Recruiting | 3 | 89 | RoW | [F-18]Florastamin | FutureChem | High Risk Prostate Carcinoma | 12/24 | 12/24 | | |
NCT05004285: Evaluate the Clinical Usefulness of [F-18]Florastamin PET/CT Imaging Diagnosis Compared to MRI Diagnosis |
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| Recruiting | 3 | 398 | RoW | [F-18]Florastamin | FutureChem | High Risk Prostate Carcinoma | 07/24 | 07/24 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
| Recruiting | 3 | 450 | Europe, Canada, Japan, US, RoW | Dordaviprone (ONC201), Dordaviprone (ONC201) + Placebo, Placebo | Chimerix | H3 K27M, Glioma | 08/26 | 08/26 | | |
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EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
OPTIMAL, NCT03315364: Oral Paclitaxel Trial In Recurrent and Metastatic Breast Cancer As 1st Line Therapy |
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| Active, not recruiting | 2/3 | 549 | Europe, RoW | Oral paclitaxel, Liporaxel®, Paclitaxel injection, Taxol® | Daehwa Pharmaceutical Co., Ltd. | Recurrent or Metastatic Breast Cancer | 02/24 | 12/25 | | |
NCT05445128: Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease |
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| Terminated | 2 | 1 | US | MGTA-145, Plerixafor | Ensoma, bluebird bio | Sickle Cell Disease | 12/22 | 02/23 | | |
NCT05733624: Clinical Trial to Evaluate the Safety and Efficacy of SCAI-001 Compared to Restasis |
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| Completed | 2 | 116 | RoW | SCAI-001 0.01% eyedrop, Cyclosporine 0.01%, SCAI-001 0.02% eyedrop, Cyclosporine 0.02%, Restasis 0.05% eyedrop, Cyclosporine 0.05% | SCAI Therapeutics | Dry Eye Syndromes | 08/23 | 02/24 | | |
NCT05819658: GV1001 Subcutaneous(SC) for the Treatment of Progressive Supranuclear Palsy (PSP) |
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| Completed | 2 | 78 | RoW | GV1001 Placebo, Normal saline, GV1001 0.56mg, Tertomotide 0.84mg, GV1001 1.12mg, Tertomotide 1.68mg | GemVax & Kael | Progressive Supranuclear Palsy | 10/24 | 10/24 | | |
DISTINKT, NCT04414163: A Study of IMC-001 in Subjects With Relapsed or Refractory Extranodal NK/T Cell Lymphoma, Nasal Type |
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| Active, not recruiting | 2 | 23 | RoW | IMC-001, Not confirm yet | ImmuneOncia Therapeutics Inc. | Extranodal NK/T-cell Lymphoma, Nasal Type, Extranodal NK/T-cell Lymphoma | 07/24 | 02/26 | | |
LUCIDA_2, NCT05579184: [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application_2 |
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| Active, not recruiting | 2 | 20 | RoW | [177Lu]Ludotadipep | FutureChem | Metastatic Castration-resistant Prostate Cancer, mCRPC | 12/24 | 12/24 | | |
| Recruiting | 2 | 34 | RoW | Busulfan, Busulfex, Fludarabine | Keimyung University Dongsan Medical Center, Otsuka Pharmaceutical Co., Ltd. | T-cell Non-Hodgkin Lymphoma, Lymphoma, Extranodal NK-T-Cell | 12/25 | 12/27 | | |
NCT05599880: The Investigate Efficacy and Safety Evaluation of Bortezomib in Patients With Relapsed/Refractory Immune Thrombocytopenia |
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| Recruiting | 2 | 29 | RoW | Bortezomib | Seoul National University Hospital | Relapsed/Refractory Immune Thrombocytopenia | 05/26 | 12/27 | | |
| Recruiting | 1/2 | 220 | Europe, Canada, US, RoW | BOLD-100 in combination with FOLFOX Chemotherapy (Dose Expansion), BOLD-100 in combination with FOLFOX Chemotherapy (Dose Escalation) | Bold Therapeutics, Inc. | Colorectal Cancer, Pancreatic Cancer, Gastric Cancers, Cholangiocarcinoma | 06/26 | 09/26 | | |
NCT06521567: A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer |
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| Not yet recruiting | 1/2 | 131 | Europe, US, RoW | Cobolimab, Dostarlimab | GlaxoSmithKline | Melanoma | 07/28 | 10/30 | | |
ELEVATE, NCT05563220: Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer |
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| Recruiting | 1/2 | 400 | Europe, US, RoW | Elacestrant, Alpelisib, Piqray, Everolimus, Afinitor, Ribociclib, Kisqali, Palbociclib, Ibrance, Capivasertib, Truqap, Abemaciclib, Verzenio | Stemline Therapeutics, Inc. | Breast Cancer, Metastatic Breast Cancer | 12/24 | 08/26 | | |
NCT04306224: A Study of IMC-002 in Subjects With Metastatic or Locally Advanced Solid Tumors and Relapsed or Refractory Lymphomas |
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| Completed | 1 | 12 | US, RoW | IMC-002 | ImmuneOncia Therapeutics Inc. | Solid Tumor, Lymphoma | 10/22 | 10/22 | | |
NCT05276310: A Study of IMC-002 in Patients with Advanced Cancer Failed to Standard Therapy |
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| Recruiting | 1 | 49 | RoW | IMC-002 | ImmuneOncia Therapeutics Inc. | Advanced Cancer | 06/25 | 12/26 | | |
GARNET, NCT02715284: Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors |
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| Recruiting | 1 | 740 | Europe, Canada, US, RoW | Dostarlimab | Tesaro, Inc. | Neoplasms | 05/26 | 10/27 | | |
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NCT04486664: Effect of Mediterranean Diet in Dyslipidemic Patients |
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| Recruiting | N/A | 100 | RoW | Mediterranean Diet | Gangnam Severance Hospital | Dyslipidemias | 10/20 | 04/21 | | |
NCT03763604: Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer |
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| Available | N/A | | Europe, Canada, RoW | Abemaciclib, LY2835219 | Eli Lilly and Company | Metastatic Breast Cancer | | | | |
NCT05735418: The Effect of GI Biome #7 on Gut Microbiome and Health of the Elderly |
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| Completed | N/A | 60 | RoW | GI Biome #7, Placebo | Seoul National University Hospital, GI Biome | Muscle Weakness | 04/23 | 12/23 | | |
| Recruiting | N/A | 1000 | Europe, Canada, US, RoW | outcome measures for CIPN testing | University of Milano Bicocca | Chemotherapy-induced Peripheral Neuropathy, Quality of Life | 05/24 | 10/25 | | |
Kim, Myung Soo |
| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
| Active, not recruiting | 2 | 103 | Europe, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627 | Chinook Therapeutics, Inc. | IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease, Diabetic Nephropathy Type 2, Immunoglobulin A Nephropathy | 07/24 | 07/26 | | |
NCT05019222: Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam |
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| Completed | N/A | 72 | RoW | Sevoflurane based inhalation anesthesia, Remimazolam based total intravenous anesthesia | Gangnam Severance Hospital | Anterior Cervical Discectomy and Fusion (ACDF) Surgery | 08/22 | 08/22 | | |
NCT04983966: Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery |
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| Completed | N/A | 76 | RoW | Desflurane, Remimazolam | Gangnam Severance Hospital | Lumbar Fusion Surgery | 02/24 | 02/24 | | |
Park, Joon Oh |
PANOVA-3, NCT03377491: Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel |
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| Completed | 3 | 571 | Europe, Canada, US, RoW | NovoTTF-200T, TTFields, Gemcitabine, nab paclitaxel | NovoCure Ltd. | Pancreas Adenocarcinoma | 10/24 | 10/24 | | |
NCT04401709: Gemcitabine+ Capecitabine Vs Capecitabine in Curatively Resected Biliary Tract Cancer |
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| Recruiting | 3 | 490 | RoW | Gemcitabine/Capecitabine, Capecitabine | Samsung Medical Center | Biliary Tract Cancer | 03/25 | 03/25 | | |
FIRST-308, NCT05948475: Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma |
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| Recruiting | 3 | 200 | Europe, US, RoW | Tinengotinib 8 mg, Tinengotinib 10 mg, Physician's Choice | TransThera Sciences (Nanjing), Inc. | Cholangiocarcinoma | 05/26 | 08/26 | | |
| Recruiting | 2 | 250 | Europe, Canada, Japan, US, RoW | zenocutuzumab (MCLA-128), bispecific, MCLA-128 | Merus N.V. | Solid Tumours Harboring NRG1 Fusion, NSCLC Harboring NRG1 Fusion, Pancreatic Cancer Harboring NRG1 Fusion, NRG1 Fusion | 12/26 | 12/26 | | |
| Recruiting | 2 | 148 | RoW | GEN-001, Pembrolizumab, KEYTRUDA®, mFOLFOX | Genome & Company, Merck Sharp & Dohme LLC | Biliary Tract Cancer | 10/26 | 10/26 | | |
NCT04492033: A Study of CTX-009 (ABL001) in Combination With Irinotecan or Paclitaxel in Advanced or Metastatic Solid Tumor Patients |
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| Active, not recruiting | 1/2 | 92 | RoW | CTX-009 (ABL001), Paclitaxel, Irinotecan | Handok Inc., Compass Therapeutics, ABL Bio, Inc. | P1b: Advanced Solid Tumors, P2: Biliary Tract Cancer | 11/23 | 07/25 | | |
SHR-A1904-I-104, NCT05277168: A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS |
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| Recruiting | 1/2 | 83 | US, RoW | SHR-A1904 | Jiangsu HengRui Medicine Co., Ltd. | Advanced Solid Tumors | 03/26 | 05/26 | | |
MP-PDAC-01, NCT03666832: Multi-center, Open-label, Phase 1b Clinical Trial to Evaluate the Safety, Tolerability, and Exploratory Efficacy of TEW-7197 in Combination With FOLFOX in Patients With Metastatic Pancreatic Ductal Adenocarcinoma Who Have Failed First-Line Gemcitabine and Nab-Paclitaxel |
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| Recruiting | 1b | 36 | RoW | TEW-7197, TEW-7197, FOLFOX | Joon Oh Park | Metastatic Pancreatic Cancer | 12/22 | 12/23 | | |
NCT04258072: Vactosertib With Nal-IRI/FL in Metastatic Pancreatic Ductal Adenocarcinoma. |
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| Recruiting | 1b | 24 | RoW | Vactosertib, TEW-7197 | Samsung Medical Center | Pancreas Cancer | 12/22 | 03/23 | | |
NCT05557851: Minnelide Along With Abraxane Plus Gemcitabine in Patients With Metastatic Adenocarcinoma of the Pancreas |
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| Recruiting | 1b | 36 | RoW | Minnelide | Minneamrita Therapeutics LLC | Metastatic Adenocarcinoma of the Pancreas | 06/24 | 12/24 | | |
VISION, NCT04151615: VMP Regimen - Safety, Efficacy, and Optimal Dose Finding Study for Patients With Multiple Myeloma |
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| Completed | N/A | 203 | RoW | | Boryung Pharmaceutical Co., Ltd | Multiple Myeloma | 01/23 | 01/23 | | |
| Recruiting | N/A | 180 | RoW | Hand-sewn, Hemi-double stapling | Gangnam Severance Hospital | Periampullar Disease | 04/24 | 04/24 | | |
Bae, Myung Hwan |
NCT03840291: Resolution of Thrombi in Left Atrial Appendage With Edoxaban |
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| Completed | 4 | 36 | RoW | Edoxaban, Lixiana® | Keimyung University Dongsan Medical Center, Daiichi Sankyo Korea Co., Ltd., a Daiichi Sankyo Company | Atrial Fibrillation, Left Atrial Appendage Thrombosis | 10/23 | 08/24 | | |
BEAT, NCT03590730: Benefits of ICD for the Primary Prevention in Patients With Valvular Cardiomyopathy |
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| Terminated | N/A | 12 | RoW | ICD implantation | Keimyung University Dongsan Medical Center, Medtronic | Valvular Heart Disease, Implantable Cardioverter Defibrillator, Sudden Cardiac Death, Primary Prevention | 07/19 | 07/21 | | |
NCT03932604: Atrial Sensing Capability for Better Detection of Atrial Fibrillation |
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| Recruiting | N/A | 640 | RoW | Atrial sensing On mode | Samsung Medical Center, Biotronik SE & Co. KG | Implantable Cardioverter Defibrillator, Atrial Fibrillation, Cardiac Event, Cardiac Arrhythmia | 12/21 | 05/23 | | |
NCT06435416: Predictive Value of Postoperative Prognostic Nutritional Index Trajectory on 1-year Mortality After Off-pump Coronary Artery Bypass Surgery |
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| Completed | N/A | 983 | RoW | No intervention | Gangnam Severance Hospital | Patients Undergoing Off-pump Coronary Artery by Pass Surgery | 07/24 | 07/24 | | |
NCT05122078: Effects of Analgesia Nociception Index (ANI)-Guided Analgesia on Postoperative Bowel Function. |
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| Recruiting | N/A | 80 | RoW | ANI, Control | Gangnam Severance Hospital | Postoperative Bowel Function Recovery | 10/25 | 10/25 | | |
NCT06342570: Quantitative Analysis of EEG Changes in Response to Nociception |
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| Recruiting | N/A | 109 | RoW | There is no Intervention name to describe. | Gangnam Severance Hospital | Patients Undergoing Laparoscopic Surgery | 12/26 | 12/26 | | |
Park, Sun-Kyung |
ONSD, NCT04095832: The Effect of Epidural Anesthesia on the Optic Nerve Sheath Diameter in Preeclampsia |
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| Completed | N/A | 22 | RoW | Epidural anesthesia | Seoul National University Hospital | Preeclampsia | 05/23 | 05/23 | | |
NCT06165562: Pressure Supporting Ventilation and EEG-guided Emergence for Free of Unwanted Complications |
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| Recruiting | N/A | 120 | RoW | PSV, Intermittent Manual Assistance, EEG-Guidance, Obey Command, Spontaneous Respiration | Gangnam Severance Hospital | Thyroid Surgery | 12/24 | 12/24 | | |
NCT05800639: Frontal Alpha Asymmetry and Pediatric Emergence Delirium |
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| Recruiting | N/A | 80 | RoW | Ophthalmic surgery, General anesthesia | Gangnam Severance Hospital | Emergence Delirium | 03/25 | 04/25 | | |
NCT05936671: EEG and ANI Guided Anesthesia and Quality of Recovery |
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| Recruiting | N/A | 126 | RoW | EEG-and-ANI-guided anesthesia, standard anesthesia, Sevoflurane and remifentanil, EEG and ANI | Gangnam Severance Hospital | Laparoscopic Gynecological Surgery | 06/25 | 06/25 | | |
Park, Joonseong |
NCT05551832: Prevalence of Marginal Ulcer After PPPD and Preventive Effect of Proton Pump Inhibitor in Korea: A Prospective Multicenter Study |
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| Recruiting | 3 | 360 | RoW | Arm I (Placebo),, Arm II (ESMESOL) | Gangnam Severance Hospital | Pancretic Dissease (Benign/Malignancy), BIle Duct Diseae(Benign/Malignancy), Ampulla of Vater Disease (Benign/Malignancy) | 10/23 | 05/25 | | |
NCT04840680: A Study of Real-World Use of Ixazomib Citrate in People With Multiple Myeloma (MM) |
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| Completed | N/A | 191 | RoW | No Intervention | Takeda | Multiple Myeloma | 07/23 | 08/23 | | |
Kim, Jonghoon |
NCT06137755: Safety and Immunogenicity of CVI-VZV-001 for Prevention of Herpes Zoster in Healthy Adults Age 50 Years and Above |
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| Recruiting | 1 | 32 | RoW | CVI-VZV-001, Shingrix | CHA Vaccine Institute Co., Ltd. | Vaccine-Preventable Diseases, Herpes Zoster | 03/25 | 03/25 | | |
NCT04509570: A Prospective & Retrospective Study on Ectopic Lymphoid-like Structures in Chronic Skins of Autoimmune Bullous Diseases |
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| Completed | N/A | 41 | RoW | Biopsy, Steroid injection | Gangnam Severance Hospital | Autoimmune Bullous Disease | 10/22 | 10/22 | | |
Kim, Do-Hyeong |
| Completed | 3 | 60 | RoW | Celebrex, acetaminophen, and dexamethasone, Pharmacological, Saline irrigation, aspiration of pneumoperitoneum, and low pressure penumoperitoneum, Surgical | Gangnam Severance Hospital | Laparoscopic Cholecystectomy | 07/21 | 07/21 | | |
NCT05925439: Comparison of Tuohy Needle and Quincke Needle During S1 Transforaminal Epidural Injection |
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| Recruiting | N/A | 284 | RoW | Tuohy needle group, Quincke needle group | Gangnam Severance Hospital | S1 Transforaminal Epidural Block | 06/25 | 06/25 | | |
DongWoo, DongWoo |
| Completed | N/A | 100 | RoW | Arm I (MEP) | Gangnam Severance Hospital | Brain Tumor | 05/22 | 05/22 | | |
kim, jiyeong |
NCT05141136: Magnetic Resonance Imaging of Injectate in Thoracic 2 Paravertebral Block |
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| Not yet recruiting | N/A | 20 | RoW | Ultrasound probe sagittal group, Ultrasound probe transverse group | Gangnam Severance Hospital | Cervical Spinal Stenosis | 10/23 | 10/23 | | |
NCT05925439: Comparison of Tuohy Needle and Quincke Needle During S1 Transforaminal Epidural Injection |
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| Recruiting | N/A | 284 | RoW | Tuohy needle group, Quincke needle group | Gangnam Severance Hospital | S1 Transforaminal Epidural Block | 06/25 | 06/25 | | |
Kim, EunJoo |
| Recruiting | N/A | 120 | RoW | Arm I (Prepectoral),, Arm II (Subpectoral) | Gangnam Severance Hospital | Eating Disorder in Adolescents and Young Adults | 12/24 | 12/24 | | |
Park, Sunkyung |
NCT05772260: Autonomic Dysfunction and Hemodynamic Instability During Per-oral Endoscopic Myotomy |
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| Recruiting | N/A | 40 | RoW | Per-oral endoscopic myotomy, general anesthesia | Gangnam Severance Hospital | Achalasia | 02/25 | 02/25 | | |
Cho, Byungwoo |
NCT06136039: Effect of Sarcopenia on Clinical Outcome of Total Knee Arthroplasty |
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| Recruiting | N/A | 150 | RoW | Arm I (Sarcopenia), Arm II(Normal) | Gangnam Severance Hospital | Knee Osteoarthritis | 12/24 | 12/24 | | |
Jung, Jieun |
NCT06608381: Comparison Partial Versus Total Omentectomy in Minimal Invasive Distal Gastrectomy for cT3/4a Gastric Cancer (KLASS-10) |
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| Recruiting | 3 | 440 | RoW | Arm I (Total omentectomy),, Arm II (Partial omentectomy) | Gangnam Severance Hospital | Gastric Cancer | 06/31 | 12/31 | | |