GangnamSeverance Hospital
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 54 Trials 
94 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Kim, Ji Hong
ADAPT, NCT04782375: Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis B

Active, not recruiting
4
140
RoW
Stop group, discontinue antiviral treatment
Asan Medical Center
Hepatitis B, Chronic
08/24
12/24
ATTACH, NCT04780204: Effectiveness of Antiviral Treatment in Cirrhotic Patients with Low-level Hepatitis B Virus DNA Levels

Active, not recruiting
4
600
RoW
Treatment, Tenofovir alafenamide
Asan Medical Center, National Evidence-Based Healthcare Collaborating Agency
Hepatitis B, Chronic
01/27
12/27
ATTENTION, NCT03753074: Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines

Active, not recruiting
4
780
RoW
Tenofovir Alafenamide, Vemlidy
Young-Suk Lim, Samsung Medical Center, Kyunghee University Medical Center, Chung-Ang University Hosptial, Chung-Ang University College of Medicine, Seoul National University Hospital, Ulsan University Hospital, Konkuk University Medical Center, Kyungpook National University Hospital, Korea University Guro Hospital, Seoul St. Mary's Hospital, Kaohsiung Medical University, Chang Gung Memorial Hospital, E-DA Hospital, Taitung Mackay Memorial Hospital, National Cheng-Kung University Hospital, Chi Mei Medical Hospital, Chiayi Christian Hospital, St. Martin De Porress Hospital, Dalin Tzu Chi General Hospital, Taichung Veterans General Hospital, China Medical University Hospital, Seoul National University Bundang Hospital
Chronic Hepatitis b
12/31
12/31
Aladdin, NCT04618640: To Evaluate the Immunogenicity and Safety of DTaP-IPV Vaccine Administered as a Boosting Dose to Healthy Children of 4-6 Years

Recruiting
3
249
RoW
DTaP-IPV combination vaccine
Boryung Biopharma Co., Ltd.
Diphtheria, Tetanus, Pertussis, Poliomyelitis
12/20
07/21
KONCLUDE, NCT02843191: Consolidation Chemotherapy for Locally Advanced Mid or Low Rectal Cancer After Neoadjuvant Concurrent Chemoradiotherapy

Recruiting
3
358
RoW
Chemotherapy
Kyung Hee University Hospital at Gangdong, Korean Society of ColoProctology
Rectal Cancer
11/23
07/24
B-Well1, NCT05630807 / 2021-005139-22: Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 1)

Active, not recruiting
3
941
Europe, Canada, Japan, US, RoW
Bepirovirsen, Placebo
GlaxoSmithKline, GlaxoSmithKline Research & Development Limited
Chronic Hepatitis B, Hepatitis B, Chronic
11/25
05/26
TAILOR RT, NCT03488693: Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

Recruiting
3
2140
Canada, US
Radiation, No Radiation
Canadian Cancer Trials Group, Alliance for Clinical Trials in Oncology, Eastern Cooperative Oncology Group, NRG Oncology, SWOG Cancer Research Network
Breast Cancer
09/27
12/27
EASTERN, NCT04214990: Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients

Recruiting
3
1700
RoW
Aspirin 100mg, Placebo oral tablet
National Cancer Center, Korea, Incheon St.Mary's Hospital/The Catholic University, Kosin University Gospel Hospital, Pusan National University Hospital, SMG-SNU Boramae Medical Center, Chonnam National University Hospital, Chung-Ang University Hosptial, Chung-Ang University College of Medicine, Chilgok Kyungpook National University, Hallym University Medical Center, Seoul National University Hospital, Asan Medical Center
Aspirin, Gastric Cancer
12/27
12/28
NAVIGATE, NCT04365868: Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

Active, not recruiting
2b
357
Europe, Canada, US, RoW
belapectin, GR-MD-02, galactoarabino rhamnogalacturonate, Placebo
Galectin Therapeutics Inc.
Prevention of Esophageal Varices, NASH - Nonalcoholic Steatohepatitis, Cirrhosis
12/24
12/24
NCT05532124: Part A: In Patients With Chronic Liver Diseases, LAENNEC (Human Placenta Hydrolysate) is to Assess Safety and Tolerability After the Doses of Doses. Part B: Part A, it is to Determine the Optimal Dose by Evaluating Two Capacity and Placebo Groups.

Recruiting
2
49
RoW
LAENNEC (Human Placenta Hydrolysate), normal saline
Green Cross Wellbeing
Chronic Liver Disease
03/23
06/23
NCT04505436: Study to Evaluate Efficacy, Safety and Tolerability of HM15211 in Subjects

Recruiting
2
240
US, RoW
HM15211, Placebo of HM15211
Hanmi Pharmaceutical Company Limited
NASH - Nonalcoholic Steatohepatitis
05/25
11/25
CBT210-POI_P1, NCT06578039: Phase 1 Clinical Trial of CordSTEM-ST

Recruiting
1
6
RoW
umbilical cord-derived mesenchymal stem cell, CordSTEM-ST
CHABiotech CO., Ltd
Premature Ovarian Insufficiency
05/25
05/25
NCT04409652: Head Position on Preventing Emergence Cough

Completed
N/A
72
RoW
Head on bed, Head on pillow
Ajou University School of Medicine
Gallbladder Diseases
12/22
12/22
NCT05212038: An Iliopsoas Plane Block After Total Hip Arthroplasty

Completed
N/A
56
RoW
iliopsoas plane block group, sham block group
Gangnam Severance Hospital
Total Hip Arthroplasty
01/23
01/23
NCT04414956: Combining Biomarkers (AFP, AFP-L3, and PIVKA-II) and Image Tools for Early Detection of Hepatocellular Carcinoma

Recruiting
N/A
1418
RoW
AFP-L3, Lens culinaris agglutinin-reactive fraction of AFP, AFP, Alpha fetoprotein, PIVKA-II, Protein induced by vitamin K absence or antagonist-II, des-gamma-carboxy prothrombin, Sonography, Ultrasound, US, CT, Computed tomography
Korea University, Korea Unversity Ansan Hospital, Soonchunhyang University Hospital, Korea University Guro Hospital, The Catholic University of Korea, Samsung Medical Center, Asan Medical Center, Korea University Anam Hospital, Keimyung University Dongsan Medical Center, Severance Hospital, Hanyang University, Konkuk University Hospital, Seoul National University Hospital, Inje University, Chung-Ang University Hosptial, Chung-Ang University College of Medicine
Liver Cirrhosis, Hepatocellular Carcinoma, Surveillance
06/23
02/26
NCT05322902: Remimazolam Total Intravenous Anesthesia Under Analgesia Nociception Index-guidance

Completed
N/A
84
RoW
remimazolam group, propofol group
Gangnam Severance Hospital
Knee Osteoarthritis, Total Knee Arthroplasty, Remimazolam
07/23
07/23
NCT03824522: Post Marketing Surveillance Study for ADYNOVATE in South Korea

Completed
N/A
341
RoW
ADYNOVATE, PEGylated rFVIII
Takeda, Takeda Pharma Korea Co. Ltd.
Hemophilia A
01/24
01/24
NCT05871424: Transdermal Buprenorphine Patch for Laparoscopic Cholecystectomy

Completed
N/A
66
RoW
buprenorphine patch group, placebo group
Gangnam Severance Hospital
Laparoscopic Cholecystectomy
02/24
02/24
NCT05487001: Perineural Dexamethasone for Continuous Femoral Nerve Block

Completed
N/A
18
RoW
dexamethasone group, sham group
Gangnam Severance Hospital
Total Knee Arthroplasty
01/24
01/24
NCT06446193: To Evaluate the Efficacy and Safety of 'NDTx-01' in Patients With ASD or SCD

Recruiting
N/A
80
RoW
NDTx-01, TAU
Neudive Inc.
Autism Spectrum Disorder, Social Communication Disorder
03/25
03/25
NCT05938088: Mirogabalin for Total Hip Arthroplasty

Recruiting
N/A
56
RoW
Arm I (mirogabalin group), Arm II (placebo group)
Gangnam Severance Hospital
Hip Osteoarthritis
06/25
06/25
NCT06093464: Beneficial Exposome Study

Not yet recruiting
N/A
40
US
Natural Compound A (masked essential oil A), Natural Compound B (masked essential oil B)
Stanford University
Healthy
12/25
12/25
Lee, Jiwon
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis

Calendar Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis
Active, not recruiting
2/3
301
Europe, Japan, US, RoW
HZN-825 BID, Placebo, HZN-825 QD
Amgen, Horizon Therapeutics USA, Inc
Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic
09/25
09/25
NCT05654311: Performance of EEG During Emergence Agitation in Nasal Surgery.

Recruiting
N/A
55
RoW
Nasal surgery
Gangnam Severance Hospital
Nasal Surgery
10/24
10/24
NCT05669443: Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy

Recruiting
N/A
42
RoW
conventional PEEP, optimized PEEP
Gangnam Severance Hospital
Prostate Cancer
11/24
11/24
KOSMOS-II, NCT05525858: KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II

Recruiting
N/A
1000
RoW
Alectinib, Alecensa, Atezolizumab, Tecentriq, Erlotinib, Tarceva, Trastuzumab + Pertuzumab, Herceptin + Perjeta, Trastuzumab emtansine, Kadcyla, Vemurafenib, Zelboraf, Bevacizumab + Erlotinib, Avastin + Tarceva, Entrectinib, Rozlytrek, Pralsetinib, Gavreto
Seoul National University Bundang Hospital, Korean Cancer Study Group, Roche Pharma AG
Solid Tumor, Advanced Solid Tumor, Metastatic Cancer
09/26
03/27
NCT04174157: Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Recruiting
N/A
500
Europe, Japan, US, RoW
Prospective observational registry, Zolgensma
Novartis Pharmaceuticals, United BioSource, LLC
Spinal Muscular Atrophy (SMA)
06/38
06/38
Han, Dong Soo
NCT04968054: Comparison of IONM Between Remimazolam and Propofol

Completed
N/A
66
RoW
Arm I (Propofol), Arm II (Remimazolam)
Gangnam Severance Hospital
Ossification Posterior Longitudinal Ligament, Cervical Spondylotic Myelopathy
05/23
05/23
NCT04994704: Comparison of Postoperative QoR-15 Scores Between Propofol and Remimazolam

Completed
N/A
73
RoW
Propfol group, Remimazolam group
Gangnam Severance Hospital
Patients Undergoing Spine Surgery
07/23
07/23
NCT05936671: EEG and ANI Guided Anesthesia and Quality of Recovery

Recruiting
N/A
126
RoW
EEG-and-ANI-guided anesthesia, standard anesthesia, Sevoflurane and remifentanil, EEG and ANI
Gangnam Severance Hospital
Laparoscopic Gynecological Surgery
06/25
06/25
Lee, Ji Hyun
NCT06113198 / 2023-000764-58: A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of Age

Recruiting
4
50
RoW
rMenB+OMV NZ
GlaxoSmithKline, GlaxoSmithKline Biologicals SA
Meningitis, Meningococcal
04/26
09/26
PEARLY, NCT02441933: Carboplatin in EARLY Triple Negative Breast Cancer Trial ( Trial)

Active, not recruiting
3
878
RoW
taxane plus carboplatin, Taxane
Yonsei University
Breast Cancer
06/25
06/25
NCT05936658: [18F]Florastamin PET/CT Imaging Examination in Patients With Suspected Recurrent or Metastatic Prostate Cancer

Recruiting
3
89
RoW
[F-18]Florastamin
FutureChem
High Risk Prostate Carcinoma
12/24
12/24
NCT05004285: Evaluate the Clinical Usefulness of [F-18]Florastamin PET/CT Imaging Diagnosis Compared to MRI Diagnosis

Recruiting
3
398
RoW
[F-18]Florastamin
FutureChem
High Risk Prostate Carcinoma
07/24
07/24
HER2CLIMB-05, NCT05132582 / 2021-002491-39: A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer

Active, not recruiting
3
654
Europe, Canada, Japan, US, RoW
Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo
Seagen Inc., Merck Sharp & Dohme LLC
HER2 Positive Breast Cancer
05/25
10/27
ACTION, NCT05580562: ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the Study)

Calendar Jan 2026 - Dec 2026: Final data from ACTION trial for newly diagnosed H3 K27M-mutant diffuse glioma
Calendar Jan 2025 - Mar 2025: Interim data from ACTION trial for newly diagnosed H3 K27M-mutant diffuse glioma
Recruiting
3
450
Europe, Canada, Japan, US, RoW
Dordaviprone (ONC201), Dordaviprone (ONC201) + Placebo, Placebo
Chimerix
H3 K27M, Glioma
08/26
08/26
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

Recruiting
3
6000
Europe, Canada, Japan, US, RoW
Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane
Eli Lilly and Company
Breast Neoplasms
10/27
03/32
OPTIMAL, NCT03315364: Oral Paclitaxel Trial In Recurrent and Metastatic Breast Cancer As 1st Line Therapy

Active, not recruiting
2/3
549
Europe, RoW
Oral paclitaxel, Liporaxel®, Paclitaxel injection, Taxol®
Daehwa Pharmaceutical Co., Ltd.
Recurrent or Metastatic Breast Cancer
02/24
12/25
NCT05445128: Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease

Terminated
2
1
US
MGTA-145, Plerixafor
Ensoma, bluebird bio
Sickle Cell Disease
12/22
02/23
NCT05733624: Clinical Trial to Evaluate the Safety and Efficacy of SCAI-001 Compared to Restasis

Completed
2
116
RoW
SCAI-001 0.01% eyedrop, Cyclosporine 0.01%, SCAI-001 0.02% eyedrop, Cyclosporine 0.02%, Restasis 0.05% eyedrop, Cyclosporine 0.05%
SCAI Therapeutics
Dry Eye Syndromes
08/23
02/24
NCT05819658: GV1001 Subcutaneous(SC) for the Treatment of Progressive Supranuclear Palsy (PSP)

Completed
2
78
RoW
GV1001 Placebo, Normal saline, GV1001 0.56mg, Tertomotide 0.84mg, GV1001 1.12mg, Tertomotide 1.68mg
GemVax & Kael
Progressive Supranuclear Palsy
10/24
10/24
DISTINKT, NCT04414163: A Study of IMC-001 in Subjects With Relapsed or Refractory Extranodal NK/T Cell Lymphoma, Nasal Type

Active, not recruiting
2
23
RoW
IMC-001, Not confirm yet
ImmuneOncia Therapeutics Inc.
Extranodal NK/T-cell Lymphoma, Nasal Type, Extranodal NK/T-cell Lymphoma
07/24
02/26
LUCIDA_2, NCT05579184: [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application_2

Active, not recruiting
2
20
RoW
[177Lu]Ludotadipep
FutureChem
Metastatic Castration-resistant Prostate Cancer, mCRPC
12/24
12/24
RRTCLAlloSCT, NCT02859402: Allogeneic Stem Cell Transplantation in Relapsed/Refractory T-, NK/T-cell Lymphomas

Recruiting
2
34
RoW
Busulfan, Busulfex, Fludarabine
Keimyung University Dongsan Medical Center, Otsuka Pharmaceutical Co., Ltd.
T-cell Non-Hodgkin Lymphoma, Lymphoma, Extranodal NK-T-Cell
12/25
12/27
NCT05599880: The Investigate Efficacy and Safety Evaluation of Bortezomib in Patients With Relapsed/Refractory Immune Thrombocytopenia

Recruiting
2
29
RoW
Bortezomib
Seoul National University Hospital
Relapsed/Refractory Immune Thrombocytopenia
05/26
12/27
BOLD-100-001, NCT04421820: BOLD-100 in Combination with FOLFOX for the Treatment of Advanced Solid Tumours

Recruiting
1/2
220
Europe, Canada, US, RoW
BOLD-100 in combination with FOLFOX Chemotherapy (Dose Expansion), BOLD-100 in combination with FOLFOX Chemotherapy (Dose Escalation)
Bold Therapeutics, Inc.
Colorectal Cancer, Pancreatic Cancer, Gastric Cancers, Cholangiocarcinoma
06/26
09/26
NCT06521567: A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Not yet recruiting
1/2
131
Europe, US, RoW
Cobolimab, Dostarlimab
GlaxoSmithKline
Melanoma
07/28
10/30
ELEVATE, NCT05563220: Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer

Recruiting
1/2
400
Europe, US, RoW
Elacestrant, Alpelisib, Piqray, Everolimus, Afinitor, Ribociclib, Kisqali, Palbociclib, Ibrance, Capivasertib, Truqap, Abemaciclib, Verzenio
Stemline Therapeutics, Inc.
Breast Cancer, Metastatic Breast Cancer
12/24
08/26
NCT04306224: A Study of IMC-002 in Subjects With Metastatic or Locally Advanced Solid Tumors and Relapsed or Refractory Lymphomas

Completed
1
12
US, RoW
IMC-002
ImmuneOncia Therapeutics Inc.
Solid Tumor, Lymphoma
10/22
10/22
NCT05276310: A Study of IMC-002 in Patients with Advanced Cancer Failed to Standard Therapy

Recruiting
1
49
RoW
IMC-002
ImmuneOncia Therapeutics Inc.
Advanced Cancer
06/25
12/26
GARNET, NCT02715284: Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors

Checkmark MFDS approved in Korea in adult patients with recurrent or advanced dMMR/MSI-H 2L endometrial cancer
Dec 2022 - Dec 2022: MFDS approved in Korea in adult patients with recurrent or advanced dMMR/MSI-H 2L endometrial cancer
Checkmark Result from GARNET trial for dMMR endometrial cancer and other solid tumors at ESMO 2022
Sep 2022 - Sep 2022: Result from GARNET trial for dMMR endometrial cancer and other solid tumors at ESMO 2022
Checkmark Approved for recurrent or advanced endometrial cancer
More
Recruiting
1
740
Europe, Canada, US, RoW
Dostarlimab
Tesaro, Inc.
Neoplasms
05/26
10/27
NCT04486664: Effect of Mediterranean Diet in Dyslipidemic Patients

Recruiting
N/A
100
RoW
Mediterranean Diet
Gangnam Severance Hospital
Dyslipidemias
10/20
04/21
NCT03763604: Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer

Available
N/A
Europe, Canada, RoW
Abemaciclib, LY2835219
Eli Lilly and Company
Metastatic Breast Cancer
 
 
NCT05735418: The Effect of GI Biome #7 on Gut Microbiome and Health of the Elderly

Completed
N/A
60
RoW
GI Biome #7, Placebo
Seoul National University Hospital, GI Biome
Muscle Weakness
04/23
12/23
ICAVS, NCT04633655: International CIPN Assessment and Validation Study

Recruiting
N/A
1000
Europe, Canada, US, RoW
outcome measures for CIPN testing
University of Milano Bicocca
Chemotherapy-induced Peripheral Neuropathy, Quality of Life
05/24
10/25
Kim, Myung Soo
ALIGN, NCT04573478: Atrasentan in Patients With IgA Nephropathy

Active, not recruiting
3
404
Europe, Canada, Japan, US, RoW
Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo
Chinook Therapeutics, Inc.
IgA Nephropathy, Immunoglobulin A Nephropathy
12/26
12/26
AFFINITY, NCT04573920: Atrasentan in Patients With Proteinuric Glomerular Diseases

Active, not recruiting
2
103
Europe, US, RoW
Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627
Chinook Therapeutics, Inc.
IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease, Diabetic Nephropathy Type 2, Immunoglobulin A Nephropathy
07/24
07/26
NCT05019222: Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam

Completed
N/A
72
RoW
Sevoflurane based inhalation anesthesia, Remimazolam based total intravenous anesthesia
Gangnam Severance Hospital
Anterior Cervical Discectomy and Fusion (ACDF) Surgery
08/22
08/22
NCT04983966: Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery

Completed
N/A
76
RoW
Desflurane, Remimazolam
Gangnam Severance Hospital
Lumbar Fusion Surgery
02/24
02/24
Park, Joon Oh
PANOVA-3, NCT03377491: Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel

Completed
3
571
Europe, Canada, US, RoW
NovoTTF-200T, TTFields, Gemcitabine, nab paclitaxel
NovoCure Ltd.
Pancreas Adenocarcinoma
10/24
10/24
NCT04401709: Gemcitabine+ Capecitabine Vs Capecitabine in Curatively Resected Biliary Tract Cancer

Recruiting
3
490
RoW
Gemcitabine/Capecitabine, Capecitabine
Samsung Medical Center
Biliary Tract Cancer
03/25
03/25
FIRST-308, NCT05948475: Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma

Recruiting
3
200
Europe, US, RoW
Tinengotinib 8 mg, Tinengotinib 10 mg, Physician's Choice
TransThera Sciences (Nanjing), Inc.
Cholangiocarcinoma
05/26
08/26
NCT02912949 / 2014-003277-42: A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)

Recruiting
2
250
Europe, Canada, Japan, US, RoW
zenocutuzumab (MCLA-128), bispecific, MCLA-128
Merus N.V.
Solid Tumours Harboring NRG1 Fusion, NSCLC Harboring NRG1 Fusion, Pancreatic Cancer Harboring NRG1 Fusion, NRG1 Fusion
12/26
12/26
KEYNOTE-D86, NCT05998447: GEN-001 Plus Pembrolizumab for Patients With Advanced Refractory Biliary Tract Cancer

Recruiting
2
148
RoW
GEN-001, Pembrolizumab, KEYTRUDA®, mFOLFOX
Genome & Company, Merck Sharp & Dohme LLC
Biliary Tract Cancer
10/26
10/26
NCT04492033: A Study of CTX-009 (ABL001) in Combination With Irinotecan or Paclitaxel in Advanced or Metastatic Solid Tumor Patients

Active, not recruiting
1/2
92
RoW
CTX-009 (ABL001), Paclitaxel, Irinotecan
Handok Inc., Compass Therapeutics, ABL Bio, Inc.
P1b: Advanced Solid Tumors, P2: Biliary Tract Cancer
11/23
07/25
SHR-A1904-I-104, NCT05277168: A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS

Recruiting
1/2
83
US, RoW
SHR-A1904
Jiangsu HengRui Medicine Co., Ltd.
Advanced Solid Tumors
03/26
05/26
MP-PDAC-01, NCT03666832: Multi-center, Open-label, Phase 1b Clinical Trial to Evaluate the Safety, Tolerability, and Exploratory Efficacy of TEW-7197 in Combination With FOLFOX in Patients With Metastatic Pancreatic Ductal Adenocarcinoma Who Have Failed First-Line Gemcitabine and Nab-Paclitaxel

Recruiting
1b
36
RoW
TEW-7197, TEW-7197, FOLFOX
Joon Oh Park
Metastatic Pancreatic Cancer
12/22
12/23
NCT04258072: Vactosertib With Nal-IRI/FL in Metastatic Pancreatic Ductal Adenocarcinoma.

Recruiting
1b
24
RoW
Vactosertib, TEW-7197
Samsung Medical Center
Pancreas Cancer
12/22
03/23
NCT05557851: Minnelide Along With Abraxane Plus Gemcitabine in Patients With Metastatic Adenocarcinoma of the Pancreas

Recruiting
1b
36
RoW
Minnelide
Minneamrita Therapeutics LLC
Metastatic Adenocarcinoma of the Pancreas
06/24
12/24
VISION, NCT04151615: VMP Regimen - Safety, Efficacy, and Optimal Dose Finding Study for Patients With Multiple Myeloma

Completed
N/A
203
RoW
Boryung Pharmaceutical Co., Ltd
Multiple Myeloma
01/23
01/23
NCT05088564: Efficacy of Hemi-double-stapling Technique

Recruiting
N/A
180
RoW
Hand-sewn, Hemi-double stapling
Gangnam Severance Hospital
Periampullar Disease
04/24
04/24
Bae, Myung Hwan
NCT03840291: Resolution of Thrombi in Left Atrial Appendage With Edoxaban

Completed
4
36
RoW
Edoxaban, Lixiana®
Keimyung University Dongsan Medical Center, Daiichi Sankyo Korea Co., Ltd., a Daiichi Sankyo Company
Atrial Fibrillation, Left Atrial Appendage Thrombosis
10/23
08/24
BEAT, NCT03590730: Benefits of ICD for the Primary Prevention in Patients With Valvular Cardiomyopathy

Terminated
N/A
12
RoW
ICD implantation
Keimyung University Dongsan Medical Center, Medtronic
Valvular Heart Disease, Implantable Cardioverter Defibrillator, Sudden Cardiac Death, Primary Prevention
07/19
07/21
NCT03932604: Atrial Sensing Capability for Better Detection of Atrial Fibrillation

Recruiting
N/A
640
RoW
Atrial sensing On mode
Samsung Medical Center, Biotronik SE & Co. KG
Implantable Cardioverter Defibrillator, Atrial Fibrillation, Cardiac Event, Cardiac Arrhythmia
12/21
05/23
NCT06435416: Predictive Value of Postoperative Prognostic Nutritional Index Trajectory on 1-year Mortality After Off-pump Coronary Artery Bypass Surgery

Completed
N/A
983
RoW
No intervention
Gangnam Severance Hospital
Patients Undergoing Off-pump Coronary Artery by Pass Surgery
07/24
07/24
NCT05122078: Effects of Analgesia Nociception Index (ANI)-Guided Analgesia on Postoperative Bowel Function.

Recruiting
N/A
80
RoW
ANI, Control
Gangnam Severance Hospital
Postoperative Bowel Function Recovery
10/25
10/25
NCT06342570: Quantitative Analysis of EEG Changes in Response to Nociception

Recruiting
N/A
109
RoW
There is no Intervention name to describe.
Gangnam Severance Hospital
Patients Undergoing Laparoscopic Surgery
12/26
12/26
Park, Sun-Kyung
ONSD, NCT04095832: The Effect of Epidural Anesthesia on the Optic Nerve Sheath Diameter in Preeclampsia

Completed
N/A
22
RoW
Epidural anesthesia
Seoul National University Hospital
Preeclampsia
05/23
05/23
NCT06165562: Pressure Supporting Ventilation and EEG-guided Emergence for Free of Unwanted Complications

Recruiting
N/A
120
RoW
PSV, Intermittent Manual Assistance, EEG-Guidance, Obey Command, Spontaneous Respiration
Gangnam Severance Hospital
Thyroid Surgery
12/24
12/24
NCT05800639: Frontal Alpha Asymmetry and Pediatric Emergence Delirium

Recruiting
N/A
80
RoW
Ophthalmic surgery, General anesthesia
Gangnam Severance Hospital
Emergence Delirium
03/25
04/25
NCT05936671: EEG and ANI Guided Anesthesia and Quality of Recovery

Recruiting
N/A
126
RoW
EEG-and-ANI-guided anesthesia, standard anesthesia, Sevoflurane and remifentanil, EEG and ANI
Gangnam Severance Hospital
Laparoscopic Gynecological Surgery
06/25
06/25
Park, Joonseong
NCT05551832: Prevalence of Marginal Ulcer After PPPD and Preventive Effect of Proton Pump Inhibitor in Korea: A Prospective Multicenter Study

Recruiting
3
360
RoW
Arm I (Placebo),, Arm II (ESMESOL)
Gangnam Severance Hospital
Pancretic Dissease (Benign/Malignancy), BIle Duct Diseae(Benign/Malignancy), Ampulla of Vater Disease (Benign/Malignancy)
10/23
05/25
NCT04840680: A Study of Real-World Use of Ixazomib Citrate in People With Multiple Myeloma (MM)

Completed
N/A
191
RoW
No Intervention
Takeda
Multiple Myeloma
07/23
08/23
Kim, Jonghoon
NCT06137755: Safety and Immunogenicity of CVI-VZV-001 for Prevention of Herpes Zoster in Healthy Adults Age 50 Years and Above

Recruiting
1
32
RoW
CVI-VZV-001, Shingrix
CHA Vaccine Institute Co., Ltd.
Vaccine-Preventable Diseases, Herpes Zoster
03/25
03/25
NCT04509570: A Prospective & Retrospective Study on Ectopic Lymphoid-like Structures in Chronic Skins of Autoimmune Bullous Diseases

Completed
N/A
41
RoW
Biopsy, Steroid injection
Gangnam Severance Hospital
Autoimmune Bullous Disease
10/22
10/22
Kim, Do-Hyeong
NCT04788654: Multimodal Analgesia for Cholecystectomy

Completed
3
60
RoW
Celebrex, acetaminophen, and dexamethasone, Pharmacological, Saline irrigation, aspiration of pneumoperitoneum, and low pressure penumoperitoneum, Surgical
Gangnam Severance Hospital
Laparoscopic Cholecystectomy
07/21
07/21
NCT05925439: Comparison of Tuohy Needle and Quincke Needle During S1 Transforaminal Epidural Injection

Recruiting
N/A
284
RoW
Tuohy needle group, Quincke needle group
Gangnam Severance Hospital
S1 Transforaminal Epidural Block
06/25
06/25
DongWoo, DongWoo
NCT04768400: MEP and Neuromuscular Blocker

Completed
N/A
100
RoW
Arm I (MEP)
Gangnam Severance Hospital
Brain Tumor
05/22
05/22
kim, jiyeong
NCT05141136: Magnetic Resonance Imaging of Injectate in Thoracic 2 Paravertebral Block

Not yet recruiting
N/A
20
RoW
Ultrasound probe sagittal group, Ultrasound probe transverse group
Gangnam Severance Hospital
Cervical Spinal Stenosis
10/23
10/23
NCT05925439: Comparison of Tuohy Needle and Quincke Needle During S1 Transforaminal Epidural Injection

Recruiting
N/A
284
RoW
Tuohy needle group, Quincke needle group
Gangnam Severance Hospital
S1 Transforaminal Epidural Block
06/25
06/25
Kim, EunJoo
NCT05615090: Self-help Application for Eating Disorder

Recruiting
N/A
120
RoW
Arm I (Prepectoral),, Arm II (Subpectoral)
Gangnam Severance Hospital
Eating Disorder in Adolescents and Young Adults
12/24
12/24
Park, Sunkyung
NCT05772260: Autonomic Dysfunction and Hemodynamic Instability During Per-oral Endoscopic Myotomy

Recruiting
N/A
40
RoW
Per-oral endoscopic myotomy, general anesthesia
Gangnam Severance Hospital
Achalasia
02/25
02/25
Cho, Byungwoo
NCT06136039: Effect of Sarcopenia on Clinical Outcome of Total Knee Arthroplasty

Recruiting
N/A
150
RoW
Arm I (Sarcopenia), Arm II(Normal)
Gangnam Severance Hospital
Knee Osteoarthritis
12/24
12/24
Jung, Jieun
NCT06608381: Comparison Partial Versus Total Omentectomy in Minimal Invasive Distal Gastrectomy for cT3/4a Gastric Cancer (KLASS-10)

Recruiting
3
440
RoW
Arm I (Total omentectomy),, Arm II (Partial omentectomy)
Gangnam Severance Hospital
Gastric Cancer
06/31
12/31

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