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9 Active 0 Inactive 9 All	Not yet recruiting Recruiting Enrolling by invitation Active, not recruiting Available No longer recruiting	Industry lead sponsor Industry collaborator Coop Other	US Canada Japan Europe RoW	N/A 1 2 3 4	Highlight changes:- Show only changed items Enrollment:

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9 Trials

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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Desai, Amish
RESONANCE, NCT04687358: REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients	Recruiting	N/A	500	US		Kiniksa Pharmaceuticals International, plc, Kiniksa Pharmaceuticals (UK), Ltd.	Recurrent Pericarditis	02/26	02/26
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function	Recruiting	N/A	1252	Europe, Canada, US	Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump	Abiomed Inc.	Left Ventricular Dysfunction, Coronary Artery Disease	03/26	10/27
Kummer, Karla
NCT05820451: Impella Real-World Surveillance of Patients Using Sodium Bicarbonate	Completed	N/A	312	NA	Impella CP, 2.5, 5.0 and 5.5 with Sodium Bicarbonate used as purge solution, Impella RP with Sodium Bicarbonate used as purge solution	Abiomed Inc.	Cardiogenic Shock, High Risk PCI	02/24	02/24
Patel, Nainesh
ISO-SHOCK, NCT04876040: Incorporating Supersaturated Oxygen in Shock	Withdrawn	N/A	60	US	SSO2 Downstream System, PCI + Impella	TherOx	Cardiogenic Shock, STEMI	01/24	06/25
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function	Recruiting	N/A	1252	Europe, Canada, US	Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump	Abiomed Inc.	Left Ventricular Dysfunction, Coronary Artery Disease	03/26	10/27
Golwala, Harsh
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial	Recruiting	N/A	1247	Europe, Canada, US	Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System	Edwards Lifesciences	Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation	01/25	04/30
NCT05149755: Evolut™ EXPAND TAVR II Pivotal Trial	Recruiting	N/A	650	Europe, Canada, Japan, US, RoW	Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT)	Medtronic Cardiovascular	Moderate Aortic Valve Stenosis	02/26	12/34
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function	Recruiting	N/A	1252	Europe, Canada, US	Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump	Abiomed Inc.	Left Ventricular Dysfunction, Coronary Artery Disease	03/26	10/27
MVSS, NCT04736667: Mitral Valve Screening Survey	Recruiting	N/A	1000	Canada, US		Medstar Health Research Institute	Mitral Valve Disease	02/27	02/27