Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center
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 17 Trials 
19 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Furqan, Muhammad
COSTAR Lung, NCT04655976 / 2020-003433-37: Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-Small Cell Lung Cancer Who Have Progressed on Prior Anti- Programmed Death-ligand 1 (PD-[L]1) Therapy and Chemotherapy

Active, not recruiting
2/3
758
Europe, Canada, Japan, US, RoW
Cobolimab, Dostarlimab, Docetaxel
GlaxoSmithKline
Lung Cancer, Non-Small Cell
10/24
10/25
GEOMETRY mono-1, NCT02414139 / 2014-003850-15: Study of Oral cMET Inhibitor INC280 in Patients With EGFR Wild-type (wt), Advanced Non-small Cell Lung Cancer (NSCLC) (Geometry Mono-1)

Checkmark From GEOMETRY mono-1 study in patients with METex14 mNSCLC
Sep 2020 - Sep 2020: From GEOMETRY mono-1 study in patients with METex14 mNSCLC
Completed
2
373
Europe, Japan, US, RoW
Capmatinib, INC280
Novartis Pharmaceuticals
Carcinoma, Non-Small-Cell Lung
04/23
05/23
NCT04699838: Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Recruiting
2
30
US
Cisplatin, Carboplatin, Etoposide, Durvalumab, Ceralasertib
Muhammad Furqan, AstraZeneca
Extensive Stage Small Cell Lung Cancer
06/24
09/24
MOZART, NCT05903092: MOnaliZumab in Combination With durvAlumab (MEDI4736) Plus Platinum-based chemotheRapy for First-line Treatment of Extensive Stage Small Cell Lung Cancer

Recruiting
2
38
US
Durvalumab, Imfinzi, Monalizumab, Carboplatin or Cisplatin, Etoposide, VP-16
Hirva Mamdani, AstraZeneca, Barbara Ann Karmanos Cancer Institute
Small Cell Lung Cancer, SCLC, Extensive Stage Small Cell Lung Cancer
06/24
06/25
BTCRC LUN20-462, NCT04919382: Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

Recruiting
2
56
US
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG7446, RO5541267, Tecentriq, Temozolomide, CCRG-81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temodal, Temodar, Temomedac, TMZ
Dwight Owen, Genentech, Inc.
Extensive Stage Lung Small Cell Carcinoma, Metastatic Lung Small Cell Carcinoma, Recurrent Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
12/24
12/25
NCT06107374: Imaging Advanced NSCLC Patients Undergoing PD-1/PD-L1 Directed Therapy Using [18F]-FARAG

Not yet recruiting
2
20
NA
[18F]F-AraG
CellSight Technologies, Inc.
Advanced Non Small Cell Lung Cancer
12/24
03/25
BTCRC-LUN18-153, NCT04317534: Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

Recruiting
2
244
US
Pembrolizumab
Greg Durm, MD, Merck Sharp & Dohme LLC
NSCLC, Stage I
04/25
04/26
NCT06084806: Test-retest Evaluation of [18F]F-AraG PET

Not yet recruiting
2
10
US
[18F]F-ARAG PET
CellSight Technologies, Inc., University of Iowa Hospitals & Clinics
Non-small Cell Lung Cancer
10/25
10/25
KEYNOTE A99, NCT04198766: Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Recruiting
1
333
US
INBRX-106 - Hexavalent OX40 agonist antibody, Pembrolizumab 200 mg, Keytruda, Pembrolizumab 400 mg
Inhibrx, Inc., Merck Sharp & Dohme LLC
Solid Tumor, Non-Small Cell Lung Cancer, Melanoma, Head and Neck Cancer, Gastric Cancer, Renal Cell Carcinoma, Urothelial Carcinoma
02/26
05/26
DEEP-Lung-IV, NCT04994795: Predictive Multimodal Signatures Associated With Response to Treatment and Prognosis of Patients With Stage IV Non-small Cell Lung Cancer

Recruiting
N/A
4000
Europe, Canada, US, RoW
Predictive models (data collection)
Sophia Genetics SAS
Non-small Cell Lung Cancer Metastatic
12/24
02/25
NCT05236114: GEMINI-NSCLC: NSCLC Biomarker Study

Recruiting
N/A
813
US
Observation
Tempus AI, AstraZeneca
Non-Small Cell Lung Cancer
06/25
02/27
Dalia, Samir
NCT05234177: Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

Recruiting
N/A
160
US
Observation
Tempus AI
Colorectal Cancer
02/25
02/27
NCT05236114: GEMINI-NSCLC: NSCLC Biomarker Study

Recruiting
N/A
813
US
Observation
Tempus AI, AstraZeneca
Non-Small Cell Lung Cancer
06/25
02/27
NCT01817192: Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer

Recruiting
N/A
1050
Europe, US
Adjuvant Chemotherapy, Radiographic surveillance, 14-Gene Prognostic Assay
Razor Genomics, Encore Clinical
Non-Small Cell Lung Cancer
05/24
05/25
Gundala, Srilata
KontRASt-02, NCT05132075 / 2021-002605-10: Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer

Active, not recruiting
3
95
Europe, Canada, US, RoW
JDQ443, docetaxel
Novartis Pharmaceuticals, Novartis Pharma AG
Non-Small Cell Lung Cancer
09/24
05/25
PRECISION 1, NCT05103358: Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes

Active, not recruiting
2
120
US, RoW
nab-sirolimus, ABI-009
Aadi Bioscience, Inc.
Tumor, Tumor, Solid, Metastasis, Metastatic Cancer, Cancer, Cancer Metastatic, Tumors, Neoplasms, Neoplasm Metastasis, Solid Tumor, Advanced Solid Tumor, Advanced Cancer, Malignant Solid Tumor, Malignant Solid Neoplasm, Malignant Neoplasm, Malignant Tumor, TSC, TSC1, TSC2, Metastatic Solid Tumor, Metastatic Neoplasm
12/24
12/25
ELU-FRα-1, NCT05001282: A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα)

Active, not recruiting
1/2
79
US
ELU001, FA-CDC
Elucida Oncology
Ovarian Cancer, Ovarian Neoplasms, Ovarian Carcinoma, Endometrial Cancer, Ovary Cancer, Ovary Neoplasm, Ovary Disease, Ovary Metastasis, Ovarian Diseases, Ovarian Cancer Stage, Ovarian Epithelial Cancer, Ovarian Adenocarcinoma, Ovarian Serous Adenocarcinoma, Ovarian Neoplasm Epithelial, Ovarian Cancer Recurrent, Endometrial Diseases, Endometrial Adenocarcinoma, Endometrial Carcinosarcoma, Endometrial Clear Cell Adenocarcinoma, Endometrioid Adenocarcinoma, Endometrial Neoplasms, Endometrial Cancer Recurrent, Endometrioid Tumor, Fallopian Tube Cancer, Peritoneal Cancer
06/24
09/24
NCT05236114: GEMINI-NSCLC: NSCLC Biomarker Study

Recruiting
N/A
813
US
Observation
Tempus AI, AstraZeneca
Non-Small Cell Lung Cancer
06/25
02/27
NCT06207032: TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

Recruiting
N/A
500
US
Tempus AI
Cancer
06/29
06/29

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