Cibula, David |
| Active, not recruiting | 3 | 502 | Europe, Canada, Japan, US, RoW | tisotumab vedotin, TIVDAK, topotecan, vinorelbine, gemcitabine, irinotecan, pemetrexed | Seagen Inc., Genmab | Cervical Cancer | 07/23 | 08/25 | | |
| Active, not recruiting | 3 | 550 | Europe, RoW | Vaginal brachytherapy, External beam radiotherapy, Observation | Leiden University Medical Center, Dutch Cancer Society, Comprehensive Cancer Centre The Netherlands | Endometrial Cancer Stage I, Endometrial Cancer Stage II | 12/24 | 12/28 | | |
| Recruiting | 3 | 220 | Europe, Canada, US, RoW | Selinexor, KPT-330, Matching Placebo for selinexor | Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group | Endometrial Cancer | 01/25 | 01/28 | | |
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| Recruiting | 3 | 64 | RoW | Physiological intervention, Psychological intervention, Nutritional intervention | Charles University, Czech Republic, University Hospital Ostrava, University Hospital Olomouc, University Hospital Pilsen, The Faculty Hospital Na Bulovce | Ovarian Cancer, Ovarian Cancer Stage III, Ovarian Cancer Stage IV, Endometrial Cancer, Frailty | 06/25 | 06/26 | | |
| Active, not recruiting | 3 | 615 | Europe, Canada, US, RoW | Oregovomab, MAb-B43.13, Paclitaxel, Taxol, Carboplatin, Paraplatin, Placebo | CanariaBio Inc., Gynecologic Oncology Group, Iqvia Pty Ltd | Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma, Fallopian Tube Neoplasms, Fallopian Tube Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Peritoneal Cancer, Peritoneal Carcinoma, Peritoneal Neoplasms | 09/25 | 08/27 | | |
| Recruiting | 3 | 514 | RoW | No adjuvant therapy, Adjuvant radiotherapy | The Central and Eastern European Gynecologic Oncology Group | Cervical Cancer | 12/29 | 12/32 | | |
| Completed | N/A | 600 | RoW | Sentinel lymph node biopsy, At least unilateral systematic pelvic lymph node dissection | Charles University, Czech Republic | Cervical Cancer | 12/22 | 02/24 | | |
| Recruiting | N/A | 83 | Europe, RoW | SLN side-specific detection rate using radioactive tracer with/without blue dye and ICG tracer. | University Medical Centre Maribor | Endometrial Cancer, Sentinel Lymph Node | 01/23 | 01/24 | | |
| Active, not recruiting | N/A | 989 | Europe, Canada, Japan, RoW | SLN biopsy only, SLN biopsy + PLN dissection | Centre Hospitalier Universitaire de Besancon, ARCAGY/ GINECO GROUP, European Network of Gynaecological Oncological Trial Groups (ENGOT) | Cervical Cancer | 05/27 | 05/29 | | |
Ďuraš, Juraj |
| Not yet recruiting | 2 | 21 | RoW | Polatuzumab vedotin, Polivy, Bendamustine Hydrochloride, Bendamustine Accord, Bendamustine Glenmark, Bendamustine KABI, Rituximab, Mabthera, Rixathon, Truxima | Czech Lymphoma Study Group | Lymphoma, Mantle-Cell | 08/26 | 08/27 | | |
Roubec, Martin |
EMIAS, NCT05153642: Emergent Microsurgical Intervention in Acute Stroke Patients After Mechanical Thrombectomy Failure Trial |
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| Recruiting | N/A | 50 | RoW | Microsurgical intervention | University Hospital Ostrava, České Budějovice Hospital | Acute Stroke, Surgical Procedure | 12/22 | 12/22 | | |
Tension, NCT03094715: Efficacy and Safety of Thrombectomy in Stroke With Extended Lesion and Extended Time Window |
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| Terminated | N/A | 253 | Europe, Canada, RoW | Thrombectomy, Mechanical thrombectomy, Best medical care, Control group | University Hospital Heidelberg, Karolinska University Hospital, Eppdata GmbH Hamburg, Germany, Aarhus University Hospital, Medical University Innsbruck, Groupe Hospitalier Pitie-Salpetriere, Oslo University Hospital, University Hospital, Martin, Charles University, Czech Republic, Hospices Civils de Lyon, CHU de Reims, Epidemiological and Clinical Research Information Network, STROKE ALLIANCE FOR EUROPE, International Consortium for Health Outcome Measurement, Inc., Europan Society for Minimally Invasive Neurological Therapy, Universitätsklinikum Hamburg-Eppendorf | Stroke, Acute, Cerebral Stroke, Cerebrovascular Stroke, Apoplexy; Brain | 05/23 | 11/23 | | |
NCT04910217: Robot-Assisted Gait Therapy in the Subacute Phase of First Ischemic Stroke |
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| Recruiting | N/A | 80 | RoW | Conventional rehabilitation, Leg/lower body exerciser device intervention., Lokomat intervention | University Hospital Ostrava, Masaryk University, VSB - Technical University of Ostrava | Ischemic Stroke | 12/25 | 12/25 | | |
Klat, Jaroslav |
| Recruiting | 3 | 220 | Europe, Canada, US, RoW | Selinexor, KPT-330, Matching Placebo for selinexor | Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group | Endometrial Cancer | 01/25 | 01/28 | | |
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| Recruiting | N/A | 83 | Europe, RoW | SLN side-specific detection rate using radioactive tracer with/without blue dye and ICG tracer. | University Medical Centre Maribor | Endometrial Cancer, Sentinel Lymph Node | 01/23 | 01/24 | | |
| Active, not recruiting | N/A | 989 | Europe, Canada, Japan, RoW | SLN biopsy only, SLN biopsy + PLN dissection | Centre Hospitalier Universitaire de Besancon, ARCAGY/ GINECO GROUP, European Network of Gynaecological Oncological Trial Groups (ENGOT) | Cervical Cancer | 05/27 | 05/29 | | |
Kubala, Otakar |
NCT05161507: Magseed and Magtrace Localization for Breast Cancer |
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| Completed | N/A | 70 | RoW | Magseed, Magtrace, Axillary lymph node metastasis - needle biopsy | University Hospital Ostrava | Breast Carcinoma, Breast Carcinoma Metastatic in Lymph Node | 12/21 | 12/23 | | |
| Completed | N/A | 100 | RoW | Targeted axillary dissection | University Hospital Ostrava, Silesian Hospital in Opava, Masaryk Memorial Cancer Institute, EUC Clinic in Zlín, Institute for the Care of Mother and Child, Prague, Czech Republic, University of Ostrava | Breast Cancer | 01/23 | 05/23 | | |
Prokop, Jiřà |
NCT05161507: Magseed and Magtrace Localization for Breast Cancer |
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| Completed | N/A | 70 | RoW | Magseed, Magtrace, Axillary lymph node metastasis - needle biopsy | University Hospital Ostrava | Breast Carcinoma, Breast Carcinoma Metastatic in Lymph Node | 12/21 | 12/23 | | |
Vávra, Petr |
NCT05161507: Magseed and Magtrace Localization for Breast Cancer |
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| Completed | N/A | 70 | RoW | Magseed, Magtrace, Axillary lymph node metastasis - needle biopsy | University Hospital Ostrava | Breast Carcinoma, Breast Carcinoma Metastatic in Lymph Node | 12/21 | 12/23 | | |
NCT03986736: Markers of Tissue Injury and Rhabdomyolysis in Patients With Major Trauma |
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| Completed | N/A | 150 | RoW | Laboratory analysis - upon admission, Laboratory analysis - 24 hours after injury | University Hospital Ostrava | Tissue Injury, Major Trauma, Rhabdomyolysis | 12/22 | 12/22 | | |
| Completed | N/A | 100 | RoW | Targeted axillary dissection | University Hospital Ostrava, Silesian Hospital in Opava, Masaryk Memorial Cancer Institute, EUC Clinic in Zlín, Institute for the Care of Mother and Child, Prague, Czech Republic, University of Ostrava | Breast Cancer | 01/23 | 05/23 | | |
NCT04444479: Insertion of PICC With Intracavitary ECG Navigation |
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| Completed | N/A | 450 | RoW | ECG verification, X-ray verification | University Hospital Ostrava | Long-term Venous Access | 01/23 | 04/23 | | |
NCT04466579: Influence of Monitoring the Depth of General Anesthesia Upon the Incidence of PONV and Emergence Delirium in Children Undergoing Endoscopic Adenoidectomy in General Anesthesia |
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| Completed | N/A | 100 | RoW | BIS monitor, Standard care | University Hospital Ostrava | Postoperative Nausea, Postoperative Vomiting, Emergence Delirium | 05/23 | 06/23 | | |
Cvek, Jakub |
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
NCT04612140: STereotactic Ablative Radiosurgery of Recurrent Ventricular Tachycardia in Structural Heart Disease |
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| Recruiting | N/A | 100 | RoW | Radiosurgery, Repeated catheter ablation | University Hospital Ostrava, Institute for Clinical and Experimental Medicine, Hospital Podlesi | Ventricular Tachycardia | 12/25 | 12/25 | | |
| Recruiting | N/A | 10 | RoW | Chemotherapy, Radiotherapy (RT) + Stereotactic Body Ratio Therapy (SBRT), Maintenance chemotherapy | University Hospital Ostrava | Non Small Cell Lung Cancer | 12/24 | 12/25 | | |
| Recruiting | N/A | 10 | RoW | Radiosurgery of ganglion stellatum | University Hospital Ostrava, Nemocnice AGEL Trinec-Podlesi a.s. | Coronary Artery Disease, Angina Pectoris, Myocardial Ischemia | 12/24 | 12/24 | | |
| Recruiting | N/A | 120 | RoW | Dose escalation | University Hospital Olomouc, Masaryk Memorial Cancer Institute, University Hospital Ostrava | Head and Neck Cancer, Hypoxia, FMISO, Dose Escalation | 06/25 | 06/30 | | |
Pleva, Leoš |
| Active, not recruiting | N/A | 3326 | Europe, RoW | SELUTION SLR, DES | M.A. Med Alliance S.A. | Coronary Artery Disease | 08/25 | 07/30 | | |
Resova, Kamila |
| Active, not recruiting | 3 | 511 | Europe, US, RoW | HLX10, Serplulimab, carboplatin/cisplatin-etoposide, Thoracic radiotherapy, Placebo, Prophylactic Cranial Irradiation (PCI) | Shanghai Henlius Biotech, Shanghai Henlius Biotech, Inc. | Limited-Stage Small Cell Lung Cancer | 07/25 | 12/26 | | |
Evin, Lukáš |
NCT05726695: The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases |
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| Active, not recruiting | N/A | 200 | RoW | microRNA test, Heart ultrasound examination | University Hospital Ostrava | Heart Failure, Heart Dilation, Left Ventricular Hypertrophy | 12/22 | 12/23 | | |