| Liu, Wen |
| Completed | 3 | 264 | Europe, Japan, US, RoW | Depemokimab (GSK3511294), Placebo | GlaxoSmithKline | Nasal Polyps | 07/24 | 08/24 | | |
| Recruiting | 3 | 2750 | Europe, Canada, RoW | Spironolactone 25Mg Tablet, Placebo Oral Tablet | Population Health Research Institute, Canadian Institutes of Health Research (CIHR) | Endstage Renal Disease | 07/25 | 04/26 | | |
NCT06322394: BXOS110 Injection in the Treatment of Acute Ischaemic Stroke |
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| Recruiting | 2 | 300 | RoW | high-dose BXOS110, BXOS110, low-dose BXOS110, Placebo | Biocells (Beijing) Biotech Co.,Ltd | Acute Ischemic Stroke | 03/25 | 09/25 | | |
NCT05865496: A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps |
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| Active, not recruiting | 2 | 90 | RoW | 611, Placebo | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | Sinusitis, Nasal Polyps, Polyps | 05/24 | 07/24 | | |
NCT06451640: A Extension Clinical Study of TQC2731 Injection in the Treatment of Chronic Sinusitis With Nasal Polyps |
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| Recruiting | 2 | 60 | RoW | 210mg of TQC2731 injection, 420mg of TQC2731 injection | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Chronic Rhinosinusitis With Nasal Polyps | 05/25 | 02/26 | | |
NCT06439381: Long-term Safety and Efficacy of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps |
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| Recruiting | 2 | 120 | RoW | 300mg/600mg of TQH2722 injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Chronic Rhinosinusitis | 10/25 | 11/25 | | |
NCT06089278: A Clinical Study of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps. |
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| Recruiting | 2 | 160 | RoW | 300mg of TQH2722 injection, 600mg of TQH2722 injection, TQH2722 injection matching placebo | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Sinusitis | 05/25 | 05/25 | | |
NCT06036927: A Clinical Study of TQC2731 Injection in the Treatment of Chronic Rhinosinusitis With Nasal Polyps |
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| Recruiting | 2 | 80 | RoW | TQC2731 injection, TQC2731 matching placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Chronic Sinusitis, Nasal Polyps | 07/25 | 09/25 | | |
HEPCP, NCT04423653: The Feasibility of Telehealth HEP for CP (HEP: Home Exercise Program), (CP: Cerebral Palsy) |
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| Not yet recruiting | N/A | 20 | US | Telehealth home exercise program | University of Kansas Medical Center | Cerebral Palsy, Spastic, Telemedicine | 07/21 | 07/22 | | |
NCT03463330: Benefits of Mild Body Exercises in Parkinson's Disease |
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| Active, not recruiting | N/A | 65 | US | Qigong exercise, Mild body exercise | University of Kansas Medical Center | Parkinson Disease | 02/22 | 03/22 | | |
NCT06247553: To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors |
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| Recruiting | N/A | 72 | US | Gait Training, Leg Cycling Exercise | University of Kansas Medical Center | Stroke, Walking, Difficulty, Cardiovascular Injury | 09/25 | 09/25 | | |
| Wang, Jun |
NCT04728516: The Effect of Dual Eradication Therapy vs PPI on Gastrointestinal Bleeding in ACS Patients |
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| Not yet recruiting | 4 | 2600 | RoW | Vonoprazan-based dual eradication therapy for two weeks, amoxicillin, Pantoprazole | Qilu Hospital of Shandong University | Acute Coronary Syndrome, Helicobacter Pylori Infection | 01/23 | 06/23 | | |
| Recruiting | 4 | 40 | RoW | Thymosin Alpha1, thymalfasin, Immunosuppressant, Prednisone, Cortisone, Mycophenolate Mofetil, Tacrolimus | Jun Wang | IrAE | 11/24 | 04/25 | | |
NCT05604859: Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome(SFTS) |
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| Recruiting | 4 | 350 | RoW | Methylprednisolone, intravenous immunoglobulin, Tocilizumab, Low molecular weight heparin, conventional treatment | Qin Ning | Severe Fever With Thrombocytopenia Syndrome | 12/23 | 06/24 | | |
NCT06009042: Efficacy of Intravenous Immunoglobulin in Patients With Hemorrhagic Fever With Renal Syndrome: a Prospective Study |
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| Recruiting | 4 | 100 | RoW | IVIG 20g/d, IVIG 10g/d | Tongji Hospital | HFRS (Hemorrhagic Fever With Renal Syndrome) | 06/24 | 06/24 | | |
NCT04726501: CCCG-HD-2018 for Children and Adolescents With Newly Diagnosed Hodgkin Lymphoma |
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| Recruiting | 4 | 200 | RoW | Combined chemotherapy with or without involved-field radiotherapy | Children's Cancer Group, China, Shanghai Children's Medical Center | Hodgkin Lymphoma | 12/25 | 12/27 | | |
NCT05830500: Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinoma |
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| Recruiting | 4 | 360 | RoW | Anlotinib Hydrochloride Capsule | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Medullary Thyroid Cancer | 06/27 | 12/28 | | |
| Recruiting | 3 | 315 | RoW | TQB2450, Anlotinib, TQB2450(blank), Anlotinib(blank) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Stage III Non-small-cell Lung Cancer | 12/22 | 03/25 | | |
| Active, not recruiting | 3 | 291 | Europe, Canada, Japan, US, RoW | Selpercatinib, LY3527723, LOXO-292, Cabozantinib, Vandetanib | Loxo Oncology, Inc., Eli Lilly and Company | Medullary Thyroid Cancer | 05/23 | 02/26 | | |
NCT05042375: A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer |
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| Recruiting | 3 | 450 | RoW | camrelizumab + famitinib, pembrolizumab, camrelizumab | Jiangsu HengRui Medicine Co., Ltd. | Non-small Cell Lung Cancer | 12/23 | 12/25 | | |
JADE, NCT06256588: A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma |
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| Recruiting | 3 | 864 | Europe, Canada, Japan, US, RoW | Dostarlimab, Placebo | GlaxoSmithKline | Neoplasms, Head and Neck | 05/28 | 07/29 | | |
NCT06333821: A Study of Nimotuzumab Plus Concurrent Chemoradiotherapy Sequential Maintenance Treatment for Cervical Carcinoma |
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| Not yet recruiting | 3 | 460 | NA | Nimotuzumab, Cisplatin, External Beam Radiotherapy (EBRT), Brachytherapy, placebo for Nimotuzumab, placebo | Biotech Pharmaceutical Co., Ltd. | Cervical Cancer | 04/30 | 04/30 | | |
NCT04102982: Microwave Ablation in Combination With Camrelizumab Versus Camrelizumab in Metastatic Non-small-cell Lung Cancer |
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| Recruiting | 2 | 200 | RoW | Camrelizumab, Camrelizumab plus microwave ablation, Camrelizumab plus MWA | Shandong Provincial Hospital | NSCLC Stage IV | 10/21 | 02/22 | | |
NCT03977480: Phase II Study of Hemay007 in Patients With Active Ulcerative Colitis |
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| Terminated | 2 | 70 | RoW | Hemay007, Placebo | Tianjin Hemay Pharmaceutical Co., Ltd | Ulcerative Colitis | 08/22 | 08/22 | | |
NCT05254665: A Study of Docetaxel Polymeric Micelles for Injection in Patients With Advanced Solid Tumors |
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| Not yet recruiting | 2 | 110 | RoW | Docetaxel Polymeric Micelles for Injection | Jiangsu Simcere Pharmaceutical Co., Ltd. | Advanced Solid Tumors | 12/22 | 03/24 | | |
NCT04286958: A Study of Camrelizumab As Consolidation Therapy After Radical Concurrent Chemoradiotherapy In Locally Advanced ESCC |
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| Recruiting | 2 | 40 | RoW | Camrelizumab | Hebei Medical University Fourth Hospital | Esophageal Cancer | 12/22 | 03/23 | | |
| Recruiting | 1/2 | 280 | RoW | SAF-189s, foritinib succinate | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | Advanced Cancer, Advanced Solid Tumor, Lung Cancer, Nonsmall Cell | 12/22 | 03/26 | | |
TQB2618-AK105-Ib-02, NCT05783921: A Clinical Trial of TQB2618 Injection Combined With Penpulimab Injection and Chemotherapy Versus Penpulimab Injection Combined With Chemotherapy in First-line Treatment of Relapsed/Metastatic Head and Neck Squamous Cell Carcinoma |
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| Recruiting | 1/2 | 60 | RoW | TQB2618 injection, Penpulimab injection, Paclitaxel, Cisplatin or Carboplatin, Penpulimab injection, Paclitaxel, Cisplatin or Carboplatin | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Recurrent Squamous Cell Carcinoma of the Head and Neck, Metastatic Squamous Cell Carcinoma | 08/24 | 01/25 | | |
| Recruiting | N/A | 120 | RoW | Acupuncture, Rehabilitation, Rehabilitation treatment | Shanghai University of Traditional Chinese Medicine, Fudan University | Ischemic Stroke, Paralysis | 12/21 | 12/21 | | |
| Recruiting | N/A | 630 | Europe, US, RoW | ROX index algorithm | Hospital Universitari Vall d'Hebron Research Institute | Acute Hypoxemic Respiratory Failure | 12/24 | 06/25 | | |
NCT03921281: Evaluating the Therapeutic Effect of Scalp Acupuncture Treatment for Motor Dysfunction in Children With Cerebral Palsy |
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| Completed | N/A | 100 | RoW | scalp acupuncture treatment, Rehabilitation Treatment | Children's Hospital of Fudan University | Cerebral Palsy, Motor Dysfunction, Acupuncture | 12/22 | 12/22 | | |
NCT04853238: Chronic Obstructive Pulmonary Disease (COPD) Maintenance Treatment Patterns in China |
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| Completed | N/A | 1507 | RoW | Prospective observational cohort study | GlaxoSmithKline | Pulmonary Disease, Chronic Obstructive | 11/22 | 02/23 | | |
NCT05379491: Application of Linaclotide Capsule in Bowel Preparation for Patients at High Risk of Inadequate Bowel Preparation |
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| Completed | N/A | 720 | RoW | 3 L PEG + linaclotide, 3 L PEG + placebo | Zhiguo Liu | Colonoscopy | 06/23 | 07/23 | | |
NCT05654857: The Prevalence of Family-unit Helicobacter Pylori Infection in Jiangsu |
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| Recruiting | N/A | 4000 | RoW | PCR test in the stool | Nanjing First Hospital, Nanjing Medical University | Helicobacter Pylori Infection | 08/23 | 08/23 | | |
PROFOUND, NCT06217900: a PROspective Case Control Study to Develop and Validate a Blood Test FOr mUlti-caNcers Early Detection（） |
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| Recruiting | N/A | 16666 | RoW | | Shanghai Weihe Medical Laboratory Co., Ltd., Peking University People's Hospital | Cancer | 10/26 | 03/27 | | |
| Recruiting | N/A | 500 | RoW | | Tongji Hospital | HFRS | 12/23 | 12/23 | | |
NCT05513040: Clinical Course of Functional Dyspepsia and Factors Predicting Outcome in Patients Receiving Medication-based Treatment |
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| Recruiting | N/A | 300 | RoW | | Air Force Military Medical University, China | Functional Dyspepsia | 03/25 | 06/25 | | |
NCT05503940: Association of Multiple Medications With the Severity of Dyspepsia |
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| Recruiting | N/A | 600 | RoW | | Air Force Military Medical University, China | Dyspepsia | 12/23 | 06/24 | | |
NCT05723731: Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation |
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| Terminated | N/A | 106 | RoW | taVNS, Laxative Agent | Air Force Military Medical University, China | Chronic Constipation | 07/23 | 09/23 | | |
NCT06330727: Effects of Coffee Consumption on Metabolic Markers in Adults With Prediabetes and Obesity |
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| Recruiting | N/A | 100 | RoW | Coffee capsule, 0 sugar 0 fat black coffee, instant black coffee. Product standard code: Q/QC 0001S. Food production license number: SC10644190004159., Corn starch capsule, Edible corn starch. Product standard code: GB 31637. Food production license number: SC10313102300041. | Nanjing First Hospital, Nanjing Medical University | Prediabetes | 10/24 | 10/24 | | |
NCT05947461: Prevention of Post-ERCP Pancreatitis by Indomethacin Vs Diclofenac |
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| Terminated | N/A | 1204 | RoW | 100mg diclofenac, 100mg indomethacin | Air Force Military Medical University, China | Post-ERCP Acute Pancreatitis, NSAIDs, Indomethacin, Diclofenac, Endoscopic Retrograde Cholangiopancreatography | 06/24 | 06/24 | | |
TACS, NCT06375408: Transcranial Alternating Current Stimulation Prevents Delirium in Patients With Subarachnoid Hemorrhage |
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| Recruiting | N/A | 74 | RoW | Real transcranial alternating electrical stimulation, Sham transcranial alternating electrical stimulation | Xuanwu Hospital, Beijing | Subarachnoid Hemorrhage | 02/26 | 03/26 | | |
NCT06323265: A Real-world Study of Adebrelimab Combined With Chemotherapy±Chest Radiotherapy in Patients With Extensive Stage Small Cell Lung Cancer |
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| Recruiting | N/A | 50 | RoW | Adebrelimab + chemotherapy, ±chest radiotherapy | Hebei Medical University Fourth Hospital | Extensive Stage Small Cell Lung Cancer | 04/25 | 04/26 | | |
NCT06063941: High-concentration Small-volume Versus Low-concentration Large-volume Iodine Solution for Esophageal Chromoendoscopy |
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| Completed | N/A | 450 | RoW | 1% Lugol's iodine solution, 5% Lugol's iodine solution | Xijing Hospital of Digestive Diseases, Ankang Central Hospital, The First Affiliated Hospital of ShiheziI University, Xi'an International Medical Center Hospital, Air Force 986 Hospital | Esophageal Squamous Cell Carcinoma | 04/24 | 04/24 | | |
| Not yet recruiting | N/A | 100 | NA | Magnetic resonance imaging scanning, FMT Protocol | LanZhou University | Inflammatory Bowel Diseases | 07/24 | 12/27 | | |
NCT05717790: Concurrent and Adjuvant Nimotuzumab Combined With Induction Chemotherapy Plus Chemoradiation in Nasopharyngeal Carcinoma |
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| Recruiting | N/A | 288 | RoW | Nimotuzumab, h-R3, BIOMAb EGFR, Gemcitabine, GEM, Cisplatin, DDP, Intensity-modulated radiotherapy, IMRT | Fourth Affiliated Hospital of Guangxi Medical University, People's Hospital of Baise, Second Affiliated Hospital of Guangzhou Medical University, Nanxishan Hospital of Guangxi Zhuang Autonomous Region, Guilin Medical University, China, LiuZhou People's Hospital, The First People's Hospital of Qinzhou, Wuzhou Red Cross Hospital, Affiliated Hospital of Youjiang Medical University for Nationalities | Nasopharyngeal Carcinoma by AJCC V8 Stage | 11/24 | 11/27 | | |
NCT04995159: Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVasâ„¢ BRS System |
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| Not yet recruiting | N/A | 2150 | RoW | Single anti-platelet therapy, SAPT strategy, Dual anti-platelet therapy, DAPT strategy | Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Heart Disease | 01/26 | 01/28 | | |
NCT04558255: A Preliminary Study on the Detection of Plasma Markers in Early Diagnosis for Lung Cancer |
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| Recruiting | N/A | 1000 | RoW | A machine-learning method which can robustly discriminate early-stage lung cancer patients from controls | Peking University People's Hospital | Lung Cancer | 12/20 | 12/21 | | |
NCT04326751: Evolution of Multiple Primary Lung Cancer (Evolution) |
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| Not yet recruiting | N/A | 20 | NA | | Peking University People's Hospital, Guangzhou Burning Rock Medical Examination Institute Co., Ltd. | Multiple Primary Lung Cancers, Lung Cancer, Non Small Cell Lung Cancer | 12/23 | 12/23 | | |
NCT05524675: The Effect of Multiple Medications on the Incidence of Organic Dyspepsia |
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| Recruiting | N/A | 500 | RoW | | Air Force Military Medical University, China | Dyspepsia | 12/23 | 06/24 | | |
| Not yet recruiting | N/A | 300 | RoW | | Peking University People's Hospital, Research Unit of Intelligence Diagnosis and treatment of early-stage non-small cell lung cancer, Chinese Academy of Medical Sciences | Non-small Cell Lung Cancer | 09/24 | 09/26 | | |
| Li, Bo |
NCT04741165: Study of HX008 in Combination With Bevacizumab or Lenvatinib for the Treatment of Advanced Hepatocellular Carcinoma (HCC) |
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| Recruiting | 2 | 72 | RoW | HX008, Bevacizumab, AVASTIN®, Lenvatinib, LENVIMA® | Taizhou Hanzhong biomedical co. LTD | Hepatocellular Carcinoma | 04/22 | 10/22 | | |
NCT05241132: Tislelizumab Combined With Chemotherapy in the Treatment of Bone Metastases of Unknown Primary |
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| Recruiting | 2 | 27 | RoW | Tislelizumab plus chemotherapy, Cisplatin, Paclitaxel | Wei Xu | Cancer of Unknown Primary, Bone Cancer Metastatic, Tislelizumab, Gene Mutation-Related Cancer, Immune Evasion, Tumor, Chemotherapy Effect | 06/23 | 10/24 | | |
NCT05124951: The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell Tumors |
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| Recruiting | 2 | 150 | RoW | Whole-ventricle irradiation, Carboplatin/etoposide, Ifosfamide/cisplatin/etoposide, Second-look surgery | Beijing Tiantan Hospital | Intracranial Germ Cell CNS Tumor, Childhood | 10/26 | 10/26 | | |
NCT04423406: The Changes in Carotid Plaque Neovascularization After Elovocumab Therapy |
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| Recruiting | N/A | 150 | RoW | | Zibo Central Hospital | Carotid Artery Diseases | 12/21 | 02/22 | | |
NCT05173467: Robot-assisted Invasion-controlled Surgery Versus Traditional-open Surgery Against Metastatic Spinal Tumor |
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| Not yet recruiting | N/A | 60 | RoW | Robot-assisted Invasion-controlled Surgery, Traditional-open Surgery | Wei Xu | Minimally Invasive Surgery, Spinal Metastases | 12/22 | 12/23 | | |
| Recruiting | N/A | 10254 | RoW | | Limeng Chen | Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder | 12/24 | 12/24 | | |
NCT04416425: Hemodynamic Change of Coronary Atherosclerotic Plaque After Evolocumab Treatment |
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| Not yet recruiting | N/A | 200 | RoW | | Zibo Central Hospital | Atherosclerosis | 12/22 | 02/23 | | |
NCT06455644: Accuracy of LAA Occluder Size Selection: CT vs. DSA During Combined AF Ablation and LAA Occlusion |
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| Recruiting | N/A | 238 | RoW | CT group, DSA group | First Affiliated Hospital of Shantou University Medical College | Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases | 10/26 | 07/31 | | |
NCT05394246: Fluorescent-labeled IgG for Liver Tumor Detection |
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| Recruiting | N/A | 60 | RoW | FluoAB | Chinese Academy of Sciences | Liver Cancer | 12/24 | 06/25 | | |
NCT05661097: Clinical Study of Hernia Ring Closure Method in Laparoscopic Abdominal Wall Hernia Repair |
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| Recruiting | N/A | 100 | RoW | Suture mode | Bo Li | Abdominal Wall Hernia | 01/25 | 01/26 | | |
| Not yet recruiting | N/A | 550 | RoW | lymph node dissection, Fluorescence-guided laparoscopic surgery, Radical operation for rectal cancer and sigmoid Cancer | Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Fudan University, Fujian Province Tumor Hospital, Guangdong Provincial People's Hospital, Shengjing Hospital, Affiliated Hospital of Qinghai University, Hebei Medical University Fourth Hospital, The Second Affiliated Hospital of Harbin Medical University, Jiangxi Provincial Cancer Hospital, The First Hospital of Jilin University, Guangdong Provincial Hospital of Traditional Chinese Medicine, Shanxi Province Cancer Hospital, Nanfang Hospital, Southern Medical University, Second People's Hospital of Yunnan Province, Binzhou Medical University, The First Affiliated Hospital of University of Science and Technology of China, First Affiliated Hospital of Chengdu Medical College, The Second People's Hospital of Yibin, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Colorectal Neoplasms, Fluorescence, Lymph Node Excision | 12/26 | 06/27 | | |
BEST-BAO, NCT05631847: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke |
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| Recruiting | N/A | 336 | RoW | Endovascular treatment, Intravenous thrombolysis (Alteplase) | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion, Thrombosis, Alteplase, Endovascular Treatment | 01/27 | 05/27 | | |
NCT05124964: Prospective Study on Quality of Life in Patients With Intracranial Germ Cell Tumors |
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| Recruiting | N/A | 150 | RoW | PedsQL 4.0 Scale, PedsQL 4.0 Generic Core Scale, Short Form-36, SF-36, Chinese Wechsler Intelligence Scale for Children, C-WISC | Beijing Tiantan Hospital | Quality of Life | 10/26 | 10/26 | | |
| Zhao, Qing |
NCT05431075: Bismuth-containing Quadruple Therapy for Helicobacter Pylori First-line Treatment of Different Tetracycline Doses |
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| Completed | 4 | 406 | RoW | Amoxicillin, Tetracycline tid, Tetracycline qid, Bismuth Potassium Citrate, Colloidal Bismuth Pectin, Esomeprazole 20mg | Shandong University, Peking University Care Luzhong Hospital, Yuncheng Traditional Chinese Medicine Hospital, Taierzhuang District People's Hospital, Zhengzhou Central Hospital, Zibo Central Hospital | Helicobacter Pylori Infection | 02/24 | 02/24 | | |
| Terminated | 3 | 52 | Europe, US, RoW | Enobosarm, VERU-024, Exemestane, Mestane | Veru Inc. | Metastatic Breast Cancer | 01/24 | 01/24 | | |
NCT05079360: Efficacy Evaluation of Sabizabulin Monotherapy Versus Active Control for Treatment of ER+HER2- Metastatic Breast Cancer |
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| Withdrawn | 2 | 200 | US | Sabizabulin, Veru-111, Exemestane monotherapy, exemestane plus everolimus, or selective estrogen receptor modulator, exemestane | Veru Inc. | Metastatic Breast Cancer | 03/24 | 05/24 | | |
NCT06686134: Comprehensive Clinical Evaluation Study of GLP-1RA |
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| Recruiting | N/A | 492 | RoW | | LI YAN | T2DM | 12/25 | 07/26 | | |
| Zhang |
NCT06683651: A Study in Chinese Patients With Acquired Blepharoptosis |
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| Recruiting | 3 | 180 | RoW | STN1013800 ophthalmic solution, STN1013800 ophthalmic solution Liquid Base, without STN1013800 | Santen Pharmaceutical Co., Ltd. | Blepharoptosis | 06/26 | 06/26 | | |
METIS, NCT02831959: Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC). |
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| Active, not recruiting | 3 | 270 | Europe, Canada, US, RoW | NovoTTF-200M device, Best Standard of Care | NovoCure GmbH | Brain Metastases From Non-small Cell Lung Cancer (NSCLC) | 12/24 | 12/24 | | |
NCT05668988: A Study of DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer (WU-KONG28) |
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| Recruiting | 3 | 320 | Europe, Canada, US, RoW | DZD9008, Pemetrexed+carboplatin | Dizal Pharmaceuticals | Non-small Cell Lung Cancer | 02/26 | 10/27 | | |
| Active, not recruiting | 3 | 9541 | Europe, Canada, Japan, US, RoW | Obicetrapib, Placebo | NewAmsterdam Pharma, Monash University | Atherosclerotic Cardiovascular Disease | 11/26 | 11/26 | | |
JACKPOT8, NCT04105010: Assessing An Oral Janus Kinase Inhibitor, AZD4205 as Monotherapy in Patients Who Have PTCL |
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| Completed | 2 | 171 | US, RoW | AZD4205 | Dizal Pharmaceuticals | Relapsed or Refractory Peripheral T Cell Lymphoma | 10/23 | 02/24 | | |
NCT06433869: The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites |
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| Recruiting | 2 | 60 | RoW | serplulimab, PD-1 inhibitor, Bevacizumab, rmhTNF-NC, recombinant human tumor necrosis factor | Sun Yat-sen University | Malignant Ascites | 12/26 | 12/26 | | |
NCT05994456: Neoadjuvant Toripalimab for dMMR/MSI-H Gastric Cancer |
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| Recruiting | 2 | 24 | RoW | PD-1 inhibitor, Toripalimab | Sun Yat-sen University | Gastric or Gastroesophageal Junction Adenocarcinoma | 12/24 | 12/24 | | |
NCT06175351: Study to Evaluate the Pharmacokinetic Characteristics, Safety, Tolerability, and Preliminary Efficacy of 9MW1911 in Patients With Chronic Obstructive Pulmonary Disease (COPD). |
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| Recruiting | 1/2 | 80 | RoW | 9MW1911, Placebo | Mabwell (Shanghai) Bioscience Co., Ltd. | Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) | 09/25 | 09/25 | | |
CCT-ANK-11, NCT06284226: An Exploratory Clinical Study to Evaluate the Safety and Efficacy of NK Cells (Combined With Standard Therapy) in the Treatment of Solid Tumor Patients |
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| Withdrawn | 1 | 20 | NA | Allogeneic NK（CCT-ANK-11) | Beijing Kejing Biotechnology Co., Ltd., Beijing Kejing Biotechnology Corp. | Solid Tumors (Pancreatic Cancer, Esophageal Cancer, Gastric Cancer, Cholangiocarcinoma, Lung Cancer and Ovarian Cancer) | 06/25 | 12/25 | | |
NCT05576415: Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye Disease |
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| Completed | 1 | 9 | RoW | Varenicline Tartrate Nasal Spray, OC-01 (varenicline solution) Nasal Spray | Ji Xing Pharmaceuticals (Shanghai) Co., Ltd., Oyster Point Pharma, Inc. | Dry Eye Disease | 04/23 | 04/23 | | |
NCT05856513: Pharmacokinetics of ZSP1273 in Participants With Hepatic Impairment |
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| Completed | 1 | 24 | RoW | ZSP1273 | Guangdong Raynovent Biotech Co., Ltd | Hepatic Impairment, Pharmacokinetics | 07/23 | 07/23 | | |
JY231、ADs, NCT06243159: JY231(Internal Clinical Drug Code) Injection for the Treatment of Refractory Autoimmune Diseases |
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| Not yet recruiting | 1 | 20 | RoW | JY231, Fludarabine, Cyclophosphamide | Shanxi Bethune Hospital | Autoimmune Diseases | 12/26 | 12/26 | | |
NCT05508100: Dose Confirmation and Dose Expansion Phase 1 Study of IO-108 and IO-108 + Anti-PD-1 in Solid Tumors |
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| Completed | 1 | 38 | RoW | IO-108, IO-108 + pembrolizumab, IO-108 + Keytruda®, IO-108 + tislelizumab | Immune-Onc Therapeutics | Advanced Solid Tumor | 04/24 | 04/24 | | |
NCT03893409: GIRH Chronic Obstructive Pulmonary Disease Observational Study |
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| Recruiting | N/A | 10000 | RoW | | zili zhang | Chronic Obstructive Pulmonary Disease | 12/20 | 12/22 | | |
NCT05761652: An Early Warning Model for Assessing the Onset, Progression and Sequelae of COVID-19 |
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| Recruiting | N/A | 378 | RoW | Observe and record | Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing YouAn Hospital, Kossamak Hospital, Kamuzu University of Health Sciences | COVID-19 | 02/24 | 06/24 | | |
PACER-PJI, NCT05284318: Prospective Cohort Study on Antibiotic Course and Efficacy After Two-stage Revision in PJI. |
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| Recruiting | N/A | 500 | RoW | Antibiotics treatment | First Affiliated Hospital of Fujian Medical University | Periprosthetic Joint Infection, Anti-Bacterial Agents | 12/23 | 12/26 | | |
| Zhao, Xiaodong |
Symphony2, NCT06353347: Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin |
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| Active, not recruiting | 3 | 551 | RoW | HTD1801, berberine ursodeoxycholate, Placebo | HighTide Biopharma Pty Ltd | Type 2 Diabetes Mellitus | 03/25 | 12/25 | | |
NCT06606483: A Study to Evaluate the Efficacy and Safety of MDR-001 in Subjects Who Are Obesity or Overweight |
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| Not yet recruiting | 2 | 300 | RoW | MDR-001, Placebo | MindRank AI Ltd | Obesity, Overweight and Obesity | 07/25 | 09/25 | | |
NCT04286815: Gene Therapy for X Linked Severe Combined Immunodeficiency |
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| Recruiting | N/A | 10 | RoW | Lentiviral Vector Gene Therapy | Children's Hospital of Chongqing Medical University | Gene Therapy | 05/23 | 05/25 | | |
NCT05455099: A Multicenter Study of Ultrafast Pulse Wave Velocity in Obese Chinese Han Adults |
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| Recruiting | N/A | 2400 | RoW | Carotid ultrasound examination 1, Carotid ultrasound examination 2 | First Hospital of China Medical University | Carotid Artery Diseases | 08/23 | 07/24 | | |
NCT05785845: Computed Tomography-Guided Stereotactic Adaptive Radiotherapy (CT-STAR) for the Treatment of Central and Ultra-Central Early-Stage Non-Small Cell Lung Cancer |
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| Recruiting | N/A | 17 | US | Computed tomography-guided stereotactic adaptive radiotherapy, CT-STAR, ETHOS | Washington University School of Medicine, Varian Medical Systems | Early Stage Non-small Cell Lung Cancer, Non-small Cell Lung Cancer | 10/25 | 10/25 | | |
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM). |
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| Not yet recruiting | N/A | 1000 | RoW | Continuous Glucose Monitoring System (GX-01S) | Nanjing First Hospital, Nanjing Medical University | Type1 Diabetes Mellitus | 10/26 | 06/27 | | |
NCT05866029: Study of the Key Techniques of Prevention and Treatment of Osteoporotic Refracture |
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| Recruiting | N/A | 2478 | RoW | Denosumab, Teriparatide | Peking Union Medical College Hospital | Osteoporotic Fractures | 09/26 | 09/26 | | |
| Zhou, Hui |
NCT06285370: A Study to Evaluate the Efficacy and Safety of KW-0761 in Chinese Subjects With Mycosis Fungoides or Sézary Syndrome Previously Treated With Systemic Therapy |
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| Recruiting | 4 | 20 | RoW | Mogamulizumab | Kyowa Kirin China Pharmaceutical Co., Ltd. | Cutaneous T-Cell Lymphoma | 10/25 | 01/26 | | |
BRUIN CLL-321, NCT04666038: Study of LOXO-305 Versus Investigator's Choice (IdelaR or BR) in Patients With Previously Treated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) |
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| Active, not recruiting | 3 | 250 | Europe, Canada, Japan, US, RoW | LOXO-305, Pirtobrutinib, Idelalisib, Zydelig, Bendamustine, Treanda, Treakisym, Ribomustin, Levact, Rituximab, Rituxan, MabThera, Truxima | Loxo Oncology, Inc., Eli Lilly and Company | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 08/23 | 05/27 | | |
BELIEVE-01, NCT05234684: A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With MCD Subtype Diffuse Large B-cell Lymphoma |
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| Recruiting | 3 | 150 | RoW | Orelabrutinib + R-CHOP, ICP-022+ R-CHOP, Placebo + R-CHOP | Beijing InnoCare Pharma Tech Co., Ltd. | Diffuse Large B Cell Lymphoma (DLBCL) | 07/24 | 12/25 | | |
BRUIN CLL-313, NCT05023980: A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) |
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| Active, not recruiting | 3 | 250 | Europe, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Bendamustine, Treanda, Treakisym, Ribomustin, Levact, Rituximab, Rituxan, MabThera, Truxima, Riabni, Ruxience | Loxo Oncology, Inc., Eli Lilly and Company | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 01/25 | 05/26 | | |
NCT05051891: A Randomized, Open-label, Multi-center, Phase III Study of Orelabrutinib in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) vs. R-CHOP Alone in Patients With Treatment-naїve Mantle Cell Lymphoma |
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| Recruiting | 3 | 356 | RoW | Orelabrutinib and R-CHOP, R-CHOP | Beijing InnoCare Pharma Tech Co., Ltd. | Treatment-naїve Mantle Cell Lymphoma | 12/24 | 12/27 | | |
BRUIN-MCL-321, NCT04662255: Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL) |
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| Active, not recruiting | 3 | 500 | Europe, Canada, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Ibrutinib, Imbruvica, Acalabrutinib, Calquence, Zanubrutinib, Brukinsa | Loxo Oncology, Inc., Eli Lilly and Company | Lymphoma, Mantle-Cell | 12/25 | 07/26 | | |
SYMPHONY-1, NCT04224493 / 2019-003333-42: A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma. |
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| Recruiting | 3 | 612 | Europe, Canada, US, RoW | Tazemetostat, EPZ-6438, IPN60200, Placebo oral tablet, Lenalidomide, Rituximab | Epizyme, Inc. | Relapsed/Refractory Follicular Lymphoma, Follicular Lymphoma, Refractory Follicular Lymphoma | 03/26 | 03/29 | | |
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| Active, not recruiting | 3 | 650 | Europe, Canada, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Ibrutinib | Loxo Oncology, Inc., Eli Lilly and Company | Chronic Lymphocytic Leukemia, Leukemia, Lymphocytic, Leukemia, B-cell, Small Lymphocytic Lymphoma | 02/25 | 08/28 | | |
NCT04600947: Study of LP002 for the Treatment of Patients With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma |
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| Not yet recruiting | 2 | 69 | RoW | LP002 | Taizhou HoudeAoke Biomedical Co., Ltd. | Primary Mediastinal Large B-Cell Lymphoma (PMBCL) | 05/22 | 05/23 | | |
