L'Hôpital de l'Enfant-Jésus
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 7 Trials 
11 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Turgeon, Alexis F
CATCO, NCT04330690: Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial

Active, not recruiting
3
2900
Canada
Artesunate, Imatinib, Infliximab, Dexamethasone, LSALT Peptide
Sunnybrook Health Sciences Centre, AbbVie, Apotex Inc., World Health Organization, University of British Columbia, Arch Biopartners Inc.
COVID-19
03/24
05/24
REMAP-CAP, NCT02735707 / 2015-002340-14: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Recruiting
3
20000
Europe, Canada, Japan, US, RoW
Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, IFN-β1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, acetylsalicylic acid, P2Y12 inhibitor, Clopidogrel, Prasugrel, Ticagrelor, No simvastatin, Simvastatin, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Ramipril, Lisinopril, Perindopril, Enalapril, Trandolapril, Captopril, Angiotensin Receptor Blockers, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Paxlovid, Remdesivir, Nirmatrelvir/ritonavir + remdesivir
UMC Utrecht, Australian and New Zealand Intensive Care Research Centre, Medical Research Institute of New Zealand, Unity Health, Berry Consultants, Global Coalition for Adaptive Research, University of Pittsburgh Medical Center, Intensive Care National Audit & Research Centre, St. Marianna University School of Medicine, Nat Intensive Care Surveillance - MORU, National University Hospital, Singapore
Community-acquired Pneumonia, Influenza, COVID-19
02/26
02/28
VICToRY, NCT04138394: VItamin C in Thermal injuRY: The Trial

Recruiting
3
666
Europe, Canada, US, RoW
Ascorbic Acid, vitamin C, placebo, saline, D5W
Clinical Evaluation Research Unit at Kingston General Hospital, Dr. Christian Stoppe, MD, Co-Principal Investigator, Wurzburg University, Wurzburg, Germany
Shock, Thermal Burn
12/26
06/27
ATTACC-CAP, NCT05848713: AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

Recruiting
3
4000
Canada, US, RoW
Heparin
University of Manitoba, Canadian Institutes of Health Research (CIHR), Research Manitoba, Ozmosis Research Inc., Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network, Canadian Critical Care Trials Group, AVANTI
Community-acquired Pneumonia
03/28
03/29
CINERGY, NCT05148715: Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function

Active, not recruiting
2
414
Canada
Tacrolimus, Prograf, Placebo
Université de Sherbrooke, McMaster University
Organ Transplant Failure or Rejection, Brain Death, Ischemic Reperfusion Injury
12/25
01/26
NCT04291235: The NEUROlogically-impaired Extubation Timing Trial (NEURO-ETT)

Not yet recruiting
N/A
332
Canada
Airway Management Pathway, Usual Care
Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR)
Acute Brain Injury
01/23
01/23
HEMOTION, NCT03260478: HEMOglobin Transfusion Threshold in Traumatic Brain Injury OptimizatioN: The Trial

Completed
N/A
742
Europe, Canada, RoW
Red Blood Cells Transfusion
CHU de Quebec-Universite Laval, Canadian Critical Care Trials Group, Canadian Traumatic Brain Injury Research Consortium, Canadian Institutes of Health Research (CIHR), Canadian Perioperative Anesthesia Clinical Trials (PACT) Group
Traumatic Brain Injury, Transfusion
10/23
02/24
LEADS, NCT05506904: Liberation From Mechanical Ventilation Using Extubation Advisor Decision Support

Recruiting
N/A
100
Canada
Extubation Advisor
Ottawa Hospital Research Institute
Airway Extubation
07/25
10/25
NeurO2, NCT04935866: Optimal Brain Oxygenation in Neurologic Intensive Care Unit : The Study

Recruiting
N/A
286
Canada
Near-infrared spectroscopy (NIRS)
CHU de Quebec-Universite Laval, Ottawa Hospital Research Institute, Canadian Critical Care Trials Group, Canadian Traumatic Brain Injury Research Consortium
Traumatic Brain Injury, Subarachnoid Hemorrhage, Brain Injuries, Near-Infrared Spectroscopy, Intensive Care Neurological Disorder, Anemia
07/24
07/25
OLEXT-3, NCT06296173: Open Lung Protective Extubation Following General Anesthesia

Recruiting
N/A
270
Canada
Protective "open-lung" extubation, Conventional extubation
Centre hospitalier de l'Université de Montréal (CHUM), CHU de Quebec-Universite Laval, The Ottawa Hospital, University Health Network, Toronto, Canadian Institutes of Health Research (CIHR)
Intra-abdominal Surgery, Anesthesia, Lung Injury, Ventilator-Induced Lung Injury, Atelectasis
12/25
04/26
OPUS, NCT06884540: Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: the Anesthesia Pilot Trial

Not yet recruiting
N/A
100
Canada
Dexmedetomidine, lidocaine, control group
CHU de Quebec-Universite Laval, Canadian Perioperative Anesthesia Clinical Trials (PACT) Group, Canadian Institutes of Health Research (CIHR), International Anesthesia Research Society (IARS)
Anesthesia, Anesthesia Complication, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity, Feasibility Studies, Patient-centredness
04/27
10/27
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Turgeon, Alexis F
CATCO, NCT04330690: Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial

Active, not recruiting
3
2900
Canada
Artesunate, Imatinib, Infliximab, Dexamethasone, LSALT Peptide
Sunnybrook Health Sciences Centre, AbbVie, Apotex Inc., World Health Organization, University of British Columbia, Arch Biopartners Inc.
COVID-19
03/24
05/24
REMAP-CAP, NCT02735707 / 2015-002340-14: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Recruiting
3
20000
Europe, Canada, Japan, US, RoW
Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, IFN-β1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, acetylsalicylic acid, P2Y12 inhibitor, Clopidogrel, Prasugrel, Ticagrelor, No simvastatin, Simvastatin, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Ramipril, Lisinopril, Perindopril, Enalapril, Trandolapril, Captopril, Angiotensin Receptor Blockers, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Paxlovid, Remdesivir, Nirmatrelvir/ritonavir + remdesivir
UMC Utrecht, Australian and New Zealand Intensive Care Research Centre, Medical Research Institute of New Zealand, Unity Health, Berry Consultants, Global Coalition for Adaptive Research, University of Pittsburgh Medical Center, Intensive Care National Audit & Research Centre, St. Marianna University School of Medicine, Nat Intensive Care Surveillance - MORU, National University Hospital, Singapore
Community-acquired Pneumonia, Influenza, COVID-19
02/26
02/28
VICToRY, NCT04138394: VItamin C in Thermal injuRY: The Trial

Recruiting
3
666
Europe, Canada, US, RoW
Ascorbic Acid, vitamin C, placebo, saline, D5W
Clinical Evaluation Research Unit at Kingston General Hospital, Dr. Christian Stoppe, MD, Co-Principal Investigator, Wurzburg University, Wurzburg, Germany
Shock, Thermal Burn
12/26
06/27
ATTACC-CAP, NCT05848713: AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

Recruiting
3
4000
Canada, US, RoW
Heparin
University of Manitoba, Canadian Institutes of Health Research (CIHR), Research Manitoba, Ozmosis Research Inc., Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network, Canadian Critical Care Trials Group, AVANTI
Community-acquired Pneumonia
03/28
03/29
CINERGY, NCT05148715: Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function

Active, not recruiting
2
414
Canada
Tacrolimus, Prograf, Placebo
Université de Sherbrooke, McMaster University
Organ Transplant Failure or Rejection, Brain Death, Ischemic Reperfusion Injury
12/25
01/26
NCT04291235: The NEUROlogically-impaired Extubation Timing Trial (NEURO-ETT)

Not yet recruiting
N/A
332
Canada
Airway Management Pathway, Usual Care
Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR)
Acute Brain Injury
01/23
01/23
HEMOTION, NCT03260478: HEMOglobin Transfusion Threshold in Traumatic Brain Injury OptimizatioN: The Trial

Completed
N/A
742
Europe, Canada, RoW
Red Blood Cells Transfusion
CHU de Quebec-Universite Laval, Canadian Critical Care Trials Group, Canadian Traumatic Brain Injury Research Consortium, Canadian Institutes of Health Research (CIHR), Canadian Perioperative Anesthesia Clinical Trials (PACT) Group
Traumatic Brain Injury, Transfusion
10/23
02/24
LEADS, NCT05506904: Liberation From Mechanical Ventilation Using Extubation Advisor Decision Support

Recruiting
N/A
100
Canada
Extubation Advisor
Ottawa Hospital Research Institute
Airway Extubation
07/25
10/25
NeurO2, NCT04935866: Optimal Brain Oxygenation in Neurologic Intensive Care Unit : The Study

Recruiting
N/A
286
Canada
Near-infrared spectroscopy (NIRS)
CHU de Quebec-Universite Laval, Ottawa Hospital Research Institute, Canadian Critical Care Trials Group, Canadian Traumatic Brain Injury Research Consortium
Traumatic Brain Injury, Subarachnoid Hemorrhage, Brain Injuries, Near-Infrared Spectroscopy, Intensive Care Neurological Disorder, Anemia
07/24
07/25
OLEXT-3, NCT06296173: Open Lung Protective Extubation Following General Anesthesia

Recruiting
N/A
270
Canada
Protective "open-lung" extubation, Conventional extubation
Centre hospitalier de l'Université de Montréal (CHUM), CHU de Quebec-Universite Laval, The Ottawa Hospital, University Health Network, Toronto, Canadian Institutes of Health Research (CIHR)
Intra-abdominal Surgery, Anesthesia, Lung Injury, Ventilator-Induced Lung Injury, Atelectasis
12/25
04/26
OPUS, NCT06884540: Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: the Anesthesia Pilot Trial

Not yet recruiting
N/A
100
Canada
Dexmedetomidine, lidocaine, control group
CHU de Quebec-Universite Laval, Canadian Perioperative Anesthesia Clinical Trials (PACT) Group, Canadian Institutes of Health Research (CIHR), International Anesthesia Research Society (IARS)
Anesthesia, Anesthesia Complication, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity, Feasibility Studies, Patient-centredness
04/27
10/27

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