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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Ladha, Karim
CARES, NCT05722002: Comparing Analgesic Regimen Effectiveness and Safety for Surgery () Trial	Recruiting	4	900	Canada, US	NSAID, Opioid, Acetaminophen	University of Michigan, Patient-Centered Outcomes Research Institute	Surgery, Pain, Postoperative	04/25	10/25
KAPA, NCT04646694: The Ketamine for Acute Postoperative Analgesia () Trial	Completed	3	40	Canada	Ketamine, Ketamine Group, Placebo, Placebo group	University Health Network, Toronto, MOUNT SINAI HOSPITAL	Postoperative Pain	03/23	06/23
PLAN, NCT04874038: Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery	Recruiting	3	1602	Canada, RoW	Lidocaine 20mg/ml, Lidocaine 2%, Placebo, 0.9% sodium chloride solution	University Health Network, Toronto, Canadian Institutes of Health Research (CIHR)	Post-mastectomy Pain Syndrome, Breast Cancer, Pain, Postoperative, Pain, Chronic	06/25	06/26
NCT03674671: Ketamine Versus Electroconvulsive Therapy in Depression	Suspended	3	240	Canada	Intravenous Ketamine, Ketalar, Electroconvulsive Therapy, ECT	University of Ottawa, McGill University, Queen's University, University Health Network, Toronto, Ontario Shores Centre for Mental Health Sciences	Depressive Disorder, Major, Bipolar Depression	12/25	12/25
PEACE-PAIN, NCT06731335: Psilocybin for Enhanced Analgesia in Chronic NEuropathic PAIN	Not yet recruiting	2	30	Canada	Psilocybin, Psychotherapy, Active Placebo	Unity Health Toronto	Chronic Neuropathic Pain, Pain Management	08/26	12/26
RECOUP, NCT03675386: Reducing Opioid Use for Chronic Pain Patients Following Surgery	Recruiting	N/A	210	Canada	Interventional Group, Transitional Pain Service Program, Control Intervention	University Health Network, Toronto	Chronic Pain, Opioid Use, Postoperative Pain, Opioid Dependence	05/24	05/24
CLEAN Wound, NCT04548661: Clinical Evaluation of Adults Undergoing Elective Surgery Utilizing Intraoperative Incisional Wound Irrigation	Recruiting	N/A	2500	Canada	Intraoperative incisional wound irrigation with povidone-iodine solution, Intraoperative incisional wound irrigation with saline	Sunnybrook Health Sciences Centre	Surgical Site Infection	08/25	08/25
Dinsmore, Michael
KAPA, NCT04646694: The Ketamine for Acute Postoperative Analgesia () Trial	Completed	3	40	Canada	Ketamine, Ketamine Group, Placebo, Placebo group	University Health Network, Toronto, MOUNT SINAI HOSPITAL	Postoperative Pain	03/23	06/23
NCT04646707: Effect of Erector Spinae (ESP) Block on Opioid Reduction and Enhanced Recovery After Posterior Cervical Spine Surgery	Recruiting	N/A	52	Canada	Erector Spinae (ESP) Block with Lidocaine/Bupivacaine, Study group, Erector Spinae (ESP) Block with placebo, Placebo group	University Health Network, Toronto	Postoperative, Pain	12/25	12/25
NCT06540625: Validation of a Novel Handheld Device for Accurate Cricoid Pressure in Healthy Volunteers	Not yet recruiting	N/A	63	NA	the use of CP device application on human subjects.	University Health Network, Toronto	Cricoid Pressure	04/25	05/25
Venkatraghavan, Lakshmikumar
KAPA, NCT04646694: The Ketamine for Acute Postoperative Analgesia () Trial	Completed	3	40	Canada	Ketamine, Ketamine Group, Placebo, Placebo group	University Health Network, Toronto, MOUNT SINAI HOSPITAL	Postoperative Pain	03/23	06/23