University Hospital Motol
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 11 Trials 
32 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Stary, Jan
FORUM, NCT01949129 / 2012-003032-22: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting
2/3
1800
Europe, Canada, RoW
VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin
St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group
Acute Lymphoblastic Leukaemia
06/25
04/30
Kala, Petr
DAPT-SHOCK-AMI, NCT03551964: Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction

Active, not recruiting
4
605
Europe, RoW
Cangrelor, intravenous P2Y12 inhibitor, Ticagrelor, oral P2Y12 inhibitor
Faculty Hospital Kralovske Vinohrady, Charles University, Czech Republic
Acute Myocardial Infarction, Cardiogenic Shock
02/24
01/25
NCT05491200 / 2021-005499-20: Comparison Of Reduced DAPT Followed by P2Y12 Inhibitor Monotherapy With Prasugrel vs stAndard Regimen in STEMI Patients

Recruiting
4
1608
Europe, RoW
Prasugrel based short DAPT, Prasugrel based standard DAPT, OCT guided revascularization, Angio guided revascularization
Research Maatschap Cardiologen Rotterdam Zuid, Abbott Medical Devices
ST Elevated Myocardial Infarction, Dual Antiplatelet Therapy
08/26
08/28
FAME2-10yFU, NCT06159231: FAME II-10-year Follow-Up

Completed
N/A
888
Europe, US, RoW
CoreAalst BV, Abbott Medical Devices
Coronary Artery Disease
05/24
05/24
NCT05305170: Eicosanoids in Human Heart Failure

Recruiting
N/A
100
RoW
Levels of EETs, DHETs and HETEs
University Hospital, Motol
Heart Failure
12/23
12/24
FERSTER, Alina
FORUM, NCT01949129 / 2012-003032-22: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting
2/3
1800
Europe, Canada, RoW
VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin
St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group
Acute Lymphoblastic Leukaemia
06/25
04/30
NCT03590171: International Study for Treatment of High Risk Childhood Relapsed ALL 2010

Recruiting
2
250
Europe, RoW
Bortezomib
Charite University, Berlin, Germany, Australian & New Zealand Children's Haematology/Oncology Group, St. Anna Kinderkrebsforschung, CCRI (co-sponsor, Austria), European Organisation for Research and Treatment of Cancer - EORTC, University Hospital Motol (Co-Sponsor Czech Republic), Copenhagen University Hospital, Rigshospitalet (co-sponsor, Denmark), Turku University Central Hospital (co-sponsor, Finland), Centre Hospitalier Universitaire de Nice, Our Lady's Chilrden's Hospital (Co-Sponsor Ireland), Tel Aviv Sourasky Medical Centre (Co-Sponsor Israel), Ospedale Pediatrico Bambino (co-sponsor, Italy), Prinses Máxima Centrum (Co-Sponsor Netherlands), Oslo University Hospital (co-sponsor, Norway), Medical University of Wroclaw (Co-Sponsor Poland), Instituto Português de Oncologia de Lisboa (co-sponsor, Portugal), Karolinska University Hospital Stockholm (co-sponsor, Sweden), Spanish Society of Pediatric Hematology and Oncology (SEHOP) (Co-Sponsor Spain), University Children's Hospital, Zurich, Central Manchester University Hospitals NHS Foundation Trust (co-sponsor, UK)
Acute Lymphoblastic Leukemia (ALL)
12/27
12/27
CHANCE, NCT02595255: AMH as a Predictor of Infertility Risk in Children With Cancer

Recruiting
N/A
275
Europe
No intervention
Erasme University Hospital, Queen Fabiola Children's University Hospital
Fertility Preservation, Lymphoma, Pediatrics Cancer, Gonadotropin-releasing Hormone Agonist
12/21
12/36
I-CML-Ped, NCT01281735: International Chronic Myeloid Leukemia Pediatric Study

Recruiting
N/A
750
Europe, Japan, RoW
Poitiers University Hospital, CIC Inserm 1402, University of Milano Bicocca, University Medical Center Groningen, University of Liege, Imperial College London, University Hospital Dresden, International BFM Study Group
Chronic Myeloid Leukemia
12/28
12/28
Sumnik, Zdenek
Lowca, NCT05078658: Low-carbohydrate Diet in Children with Type 1 Diabetes

Active, not recruiting
N/A
35
RoW
Low-carbohydrate diet, Recommended-carbohydrate diet
University Hospital, Motol, Czech Academy of Sciences
Type1diabetes
10/24
12/25
XLHRegistry, NCT03193476: Registry for Patients With X-Linked Hypophosphatemia

Recruiting
N/A
1343
Europe, RoW
Kyowa Kirin Pharmaceutical Development Ltd, Iqvia Pty Ltd
X-Linked Hypophosphatemia
02/29
07/29
Sramkova, Lucie
NCT04793919 / 2017-002383-40: Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

Recruiting
2
89
Europe, RoW
Mylotarg, GO, Arsenic Trioxide, ATO, All-trans retinoic acid, ATRA
Associazione Italiana Ematologia Oncologia Pediatrica, AIEOP
Acute Promyelocytic Leukemia
10/25
10/27
NCT03590171: International Study for Treatment of High Risk Childhood Relapsed ALL 2010

Recruiting
2
250
Europe, RoW
Bortezomib
Charite University, Berlin, Germany, Australian & New Zealand Children's Haematology/Oncology Group, St. Anna Kinderkrebsforschung, CCRI (co-sponsor, Austria), European Organisation for Research and Treatment of Cancer - EORTC, University Hospital Motol (Co-Sponsor Czech Republic), Copenhagen University Hospital, Rigshospitalet (co-sponsor, Denmark), Turku University Central Hospital (co-sponsor, Finland), Centre Hospitalier Universitaire de Nice, Our Lady's Chilrden's Hospital (Co-Sponsor Ireland), Tel Aviv Sourasky Medical Centre (Co-Sponsor Israel), Ospedale Pediatrico Bambino (co-sponsor, Italy), Prinses Máxima Centrum (Co-Sponsor Netherlands), Oslo University Hospital (co-sponsor, Norway), Medical University of Wroclaw (Co-Sponsor Poland), Instituto Português de Oncologia de Lisboa (co-sponsor, Portugal), Karolinska University Hospital Stockholm (co-sponsor, Sweden), Spanish Society of Pediatric Hematology and Oncology (SEHOP) (Co-Sponsor Spain), University Children's Hospital, Zurich, Central Manchester University Hospitals NHS Foundation Trust (co-sponsor, UK)
Acute Lymphoblastic Leukemia (ALL)
12/27
12/27
Bilkova, Alena
CAR-CF, NCT05052294: COVID-19 Antibody Responses in Cystic Fibrosis

Recruiting
N/A
50
RoW
University Hospital, Motol, Brno University Hospital
Cystic Fibrosis
09/24
09/24
Jamal, Eva S Al
PHITT, NCT03017326 / 2016-002828-85: Paediatric Hepatic International Tumour Trial

Active, not recruiting
3
450
Europe, RoW
Cisplatin, Doxorubicin, Carboplatin, 5Fluorouracil, Vincristine, Etoposide, Irinotecan, Gemcitabine, Oxaliplatin, Sorafenib
University of Birmingham, Fundació Institut Germans Trias i Pujol, University Hospital Munich, University Hospital, Bonn, University of Kiel, University Hospital Tuebingen, University of Padova, Ludwig-Maximilians - University of Munich, Medical University of Gdansk, Cliniques universitaires Saint-Luc- Université Catholique de Louvain, Motol University Hospital, Prague, Rennes University Hospital, Children's University Hospital, Ireland, University of Oslo, Princess Maxima Center for Pediatric Oncology, Andaluz Health Service, Swiss Pediatric Oncology Group, Gothia Forum - Center for Clinical Trial, The Leeds Teaching Hospitals NHS Trust, Bambino Gesù Hospital and Research Institute, Newcastle University Centre for Cancer, Newcastle, Experimental Cancer Medicine Centres, XenTech, Evry
Hepatoblastoma, Carcinoma, Hepatocellular
08/26
08/27
SAFEDRIVE, NCT06382350: Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems

Recruiting
N/A
120
RoW
MiniMed 780 G
University Hospital, Motol
Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus With Hypoglycemia, Drive
09/25
05/26
Horvath, Rudolf
NCT04527380 / 2018-000681-10: A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis Categories of Enthesitis-related Arthritis (Including Juvenile Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis

Active, not recruiting
3
100
Europe, RoW
Ixekizumab, LY2439821, Adalimumab
Eli Lilly and Company
Juvenile Psoriatic Arthritis, Enthesitis Related Arthritis
02/24
04/28
JUVE-X, NCT03773965 / 2017-004471-31: A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis

Recruiting
3
190
Europe, Japan, RoW
Baricitinib, LY3009104
Eli Lilly and Company
Juvenile Idiopathic Arthritis
07/31
07/31
Kopeckova, Katerina
LOTIS 5, NCT04384484 / 2020-000241-14: Study to Evaluate Loncastuximab Tesirine With Rituximab Versus Immunochemotherapy in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Checkmark Safety run-in data from LOTIS-5 trial in combination with rituximab in r/r DLBCL at SOHO 2022
Sep 2022 - Sep 2022: Safety run-in data from LOTIS-5 trial in combination with rituximab in r/r DLBCL at SOHO 2022
Hourglass Nov 2021 - Dec 2021 : From LOTIS 5 trial in combination with rituximab for DLBCL
Hourglass Sep 2021 - Dec 2021 : Submission for r/r DLBCL
Active, not recruiting
3
440
Europe, Canada, Japan, US, RoW
Loncastuximab Tesirine, Zynlonta, ADCT-402, Rituximab, Gemcitabine, Oxaliplatin
ADC Therapeutics S.A., ADC Therapeutics SA
Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma
06/25
06/28
EPCORE DLBCL-3, NCT05660967 / 2021-005744-29: Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma

Recruiting
2
180
Europe, Japan, US, RoW
Epcoritamab, GEN3013, DuoBody®-CD3×CD20, EPKINLY™, Lenalidomide, Revlimid®
Genmab, AbbVie
Diffuse Large B-Cell Lymphoma
01/26
07/27
SPECTA, NCT02834884: Screening Cancer Patients for Efficient Clinical Trial Access

Recruiting
N/A
4975
Europe, RoW
RP-1828 IMMUcan, RP-1759 AYA/TYA, RP-1843 Arcagen, RP-1920 BioRadon
European Organisation for Research and Treatment of Cancer - EORTC
All Tumor Types
03/26
03/26
Dedeckova, Katerina
NCT03681535: Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma

Active, not recruiting
N/A
241
Europe, Japan, US, RoW
Radiation Therapy
Duke University
Diffuse Large B Cell Lymphoma
08/25
08/28
Stepanova, Monika
NCT03681535: Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma

Active, not recruiting
N/A
241
Europe, Japan, US, RoW
Radiation Therapy
Duke University
Diffuse Large B Cell Lymphoma
08/25
08/28
Neuman, Vit
Lowca, NCT05078658: Low-carbohydrate Diet in Children with Type 1 Diabetes

Active, not recruiting
N/A
35
RoW
Low-carbohydrate diet, Recommended-carbohydrate diet
University Hospital, Motol, Czech Academy of Sciences
Type1diabetes
10/24
12/25
Plzak, Jan
SPECTA, NCT02834884: Screening Cancer Patients for Efficient Clinical Trial Access

Recruiting
N/A
4975
Europe, RoW
RP-1828 IMMUcan, RP-1759 AYA/TYA, RP-1843 Arcagen, RP-1920 BioRadon
European Organisation for Research and Treatment of Cancer - EORTC
All Tumor Types
03/26
03/26
Malis, Josef
PHITT, NCT03017326 / 2016-002828-85: Paediatric Hepatic International Tumour Trial

Active, not recruiting
3
450
Europe, RoW
Cisplatin, Doxorubicin, Carboplatin, 5Fluorouracil, Vincristine, Etoposide, Irinotecan, Gemcitabine, Oxaliplatin, Sorafenib
University of Birmingham, Fundació Institut Germans Trias i Pujol, University Hospital Munich, University Hospital, Bonn, University of Kiel, University Hospital Tuebingen, University of Padova, Ludwig-Maximilians - University of Munich, Medical University of Gdansk, Cliniques universitaires Saint-Luc- Université Catholique de Louvain, Motol University Hospital, Prague, Rennes University Hospital, Children's University Hospital, Ireland, University of Oslo, Princess Maxima Center for Pediatric Oncology, Andaluz Health Service, Swiss Pediatric Oncology Group, Gothia Forum - Center for Clinical Trial, The Leeds Teaching Hospitals NHS Trust, Bambino Gesù Hospital and Research Institute, Newcastle University Centre for Cancer, Newcastle, Experimental Cancer Medicine Centres, XenTech, Evry
Hepatoblastoma, Carcinoma, Hepatocellular
08/26
08/27
HR-NBL2, NCT04221035 / 2019-001068-31: High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

Recruiting
3
800
Europe, RoW
Vincristine, L01CA02, Carboplatin, LO1XA02, Etoposide, L01CB01, Vindesine, L01CA03, Dacarbazine, L01AX04, Ifosfamide, Doxorubicin, L01DB01, Busulfan, L01AB01, Melphalan, L01AA03, Thiotepa, L01AC01, Radiotherapy, Dinutuximab Beta, L01XC16, Cisplatin, L01XA01, Temozolomide 100 MG, Irinotecan, Cyclophosphamid
Gustave Roussy, Cancer Campus, Grand Paris, PHRC, Solving Kids' Cancer Europe, Neuroblastoma UK, , BSPHO, Instituto de Investigación Sanitaria La Fe, Deutsche Krebshilfe
High-Risk Neuroblastoma, Patient With Insufficient Response Chemoimmunotherapy
11/26
11/32
Koubkova, Leona
GALAXIES Lung-301, NCT06472076: A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

Recruiting
3
1000
Europe, Canada, Japan, RoW
Dostarlimab, Belrestotug, Pembrolizumab, Placebo
GlaxoSmithKline, iTeos Therapeutics
Lung Cancer, Non-Small Cell
09/28
09/29
HLX10-020-SCLC302, NCT05353257 / 2022-002226-27: A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer

Active, not recruiting
3
511
Europe, US, RoW
HLX10, Serplulimab, carboplatin/cisplatin-etoposide, Thoracic radiotherapy, Placebo, Prophylactic Cranial Irradiation (PCI)
Shanghai Henlius Biotech, Shanghai Henlius Biotech, Inc.
Limited-Stage Small Cell Lung Cancer
07/25
12/26
Šípek, Jan
Levon, NCT06171295: Pharmacokinetics and Pharmacodynamics of Levobupivacaine During Continuous Caudal Epidural Analgesia in Newborns

Completed
N/A
24
RoW
Blood draw
University Hospital, Motol
Analgesia
07/22
07/22
Slepčanová, Hana
NCT06457438: Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors

Recruiting
N/A
300
RoW
Elecsys Anti-HEV IgG, IgM
University Hospital Ostrava
Hepatitis E
12/24
12/24
NCT06456151: Invasive Candidiasis in Critical Care

Recruiting
N/A
100
RoW
Invasive candidiasis test, Urine sample collection for future research
University Hospital Ostrava, University Hospital, Motol
Invasive Candidiasis
12/25
12/27

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